A new species of Nemophora from Korea (Lepidoptera, Adelidae, Adelinae).

A new species of the genus Nemophora Hoffmannsegg, Nemophora lutea Ko & Hirowatari sp. nov. is described from Korea, which is very similar to N. smaragdaspis (Meyrick) found in India and Nepal but distinguished by its the straight deep orange median band and metallic white lines on the forewing in both sexes. Illustrations of adults and genitalia are provided, with habitat information.

The monotypic genus Nephelobotys Munroe & Mutuura, 1970 (Lepidoptera, Crambidae, Pyraustinae): two new species from Laos and a newly combined species from Korea.

The genus Nephelobotys is newly recorded from Laos and two new species Nephelobotys denticulatus sp. nov. and Nephelobotys forcipatus sp. nov. are newly described. Nephelobotys evenoralis (Walker, 1859) comb. nov., is also newly reported from Korea. Illustrations of adults and genitalia are provided. The differences with related genus Torulisquama Zhang & Li, 2010 are briefly discussed.

Two new species and a new record of the genus Meganola Dyar, 1898 (Lepidoptera, Nolidae, Nolinae) from Laos.

The paper contains the description of two new Meganola Dyar, 1898 species (M. canaliculata Cha Bae, sp. n. and M. phuana Cha Bae, sp. n.) and a new record of M. tetrodon (de Joannis, 1928) from Laos. Color figures of adults and genitalia of the examined species are provided.

A new species of Palpita Hübner from Laos (Lepidoptera, Crambidae, Spilomelinae).

A new species of the genus Palpita Hübner is described from Laos, which is very close to P. inusitata (Butler, 1879) found in Japan.

First report of the genus Neadeloides Klima, 1939 (Lepidoptera, Crambidae, Pyraustinae) in Laos, with description of a new species.

The genus Neadeloides Klima, 1939 is a small genus of the subfamily Pyraustinae (Lepidoptera, Crambidae). It was established for the type species Hoterodes cinerealis Moore, 1867 as the objective replacement name for Adeloides Warren, 1892, a homonym of Adeloides Blanchard, 1845 of Curculionidae in Coleoptera (Singh et al. 2019; Nuss et al. 2003-2020). Recently, this genus was studied by Singh et al. (2019), with the inclusion of three species: N. cinerealis (Moore, 1867) and N. nubilus Singh, Ranjan Singh, 2019 from India, and N. glaucoptera (Hampson, 1896) from Bhutan. Species of Neadeloides can be distinguished by the following characters. In the male, the antenna are very long, about twice the length of the forewing; forewing narrow, with a produced apex; termen extremely oblique; in the female, antenna almost same length of the forewing; forewing wider than male; in the male genitalia, uncus broad, inverted U-shaped, ventrally concave, with a small, sub-apical lateral projection on both sides; valva elongated flap-like, membranous at base and sclerotized from middle to apex; costal margin rather concave, nearly straight; dorsum of valva outwardly angled at middle or roughly straight; sacculus process hook-shaped or broad rectangular, with setose apical flap (Singh et al. 2019).

Development of a Novel ssDNA Sequence for a Glycated Human Serum Albumin and Construction of a Simple Aptasensor System Based on Reduced Graphene Oxide (rGO).

Diabetes is one of the top 10 global causes of death. About one in 11 global adults have diabetes. As the disease progresses, the mortality rate increases, and complications can develop. Thus, early detection and effective management of diabetes are especially important. Herein, we present a novel glycated human serum albumin (GHSA) aptamer, i.e., GABAS-01, which has high affinity and specificity. The aptamer was selected by reduced graphene oxide-based systematic evolution of ligands by exponential enrichement (rGO-based SELEX) against GHSA. After five rounds of selection through gradually harsher conditions, GABAS-01 with high affinity and specificity for the target was obtained. GABAS-01 was labeled by FAM at the 5'-end and characterized by measuring the recovery of a fluorescence signal that is the result of fluorescence quenching effect of rGO. As a result, GABAS-01 had low-nanomolar Kd values of 1.748 ± 0.227 nM and showed a low limit of detection of 16.40 µg/mL against GHSA. This result shows the potential application of GABAS-01 as an effective on-site detection probe of GHSA. In addition, these properties of GABAS-01 are expected to contribute to detection of GHSA in diagnostic fields.

New record of the genus Leucinodella Strand from Laos (Lepidoptera, Crambidae, Spilomelinae), with description of a new species.

The genus Leucinodella Strand (1918) is reported from Laos for the first time, with a new species, Leucinodella banthaensis n. sp., and one newly recorded species, Leucinodella leucostola (Hampson, 1896). A key to Leucinodella species in Laos is provided, with illustrations of adults and genitalia.

Exoasota pursatensis Ko amp; Bae, new genus and species of the Spilomelinae (Lepidoptera: Pyraloidea: Crambidae) from Indochina.

Exoasota pursatensis Ko Bae, gen. nov. sp. nov. (Lepidoptera: Pyraloidea: Crambidae) is described from Indochina (Cambodia, Thailand, Vietnam, Myanmar). The new genus Exoasota is assigned to Spilomelinae on the basis of the morphological evidence, including the tympanal organs and genitalia. In addition, we provide comparisons with genera Epiparbattia Caradja (Crambidae, Pyraustinae) and Asota Hübner (Erebidae, Aganainae). Illustrations of adults, genitalia, and tympanal characters are provided.

A new species of the genus Tatargina (Lepidoptera, Erebidae, Arctiinae) from Cambodia.

A new species of the Tatargina Butler, T. erythromelaena Bayarsaikhan Bae, n. sp., is described from Cambodia, with a recorded species, T. picta (Walker). Illustrations of adults and male genitalia of Cambodia and Thailand species are presented.

Prevalence and associated factors of influenza vaccination coverage in Korean adults with cardiovascular disease.

Infection with influenza virus increases morbidity and mortality in patients with risk factors, including cardiovascular disease (CVD). This study aimed to evaluate factors associated with influenza vaccination coverage in Korean CVD patients.We included 19,599 adults from the 2010 to 2012 Korea National Health and Nutrition Examination Survey. Influenza vaccination rates were compared in subjects with and without CVD. Logistic regression analysis was performed to identify factors associated with influenza vaccination in Korean adults with CVD before and after stratification for age (<65 and ≥65 years).Significantly higher vaccination rates were observed in individuals with CVD than in those without CVD (61.4% vs 31.0%, P < .001). However, young individuals (19-49 years) had decreased influenza vaccination rates, with no difference based on CVD status (20.3% vs 21.6%, P = .859). A lack of private insurance (odds ratio [OR], 0.47; 95% confidence interval [CI], 0.23-0.98) and recent health screening (OR, 4.56; 95% CI, 1.90-10.92) were independent factors for influenza vaccination in CVD patients aged <65 years, whereas female sex (OR, 3.71; 95% CI, 1.24-11.07) and less education (OR, 4.59; 95% CI, 1.27-16.61) were independent factors in CVD patients aged ≥65 years.Improving influenza vaccination coverage for Korean adults with CVD is important, especially in young patients. For young patients with CVD, influenza vaccination status is independently associated with the presence of private insurance and recent health screening. This finding could help establish public health policies to promote influenza vaccination in this population.

Review of the genus Meganola Dyar, 1898 (Lepidoptera: Nolidae, Nolinae) from Korea, with the description of a new species.

The genus Meganola Dyar, 1898 is reviewed for Korea, with 12 species, including the new species, Meganola parki Oh Cha, sp. n. Illustrations of adults and genitalia of all the Korean species are provided, with a key to species of Meganola based on the external morphology and male genitalia. All known host plants are provided, some of them newly recorded.

A new species of the genus Eugoa Walker, 1858 (Lepidoptera, Erebidae, Arctiinae) from Cambodia.

A new Lithosiini species, Eugoa leucomelaena n. sp. is described from Cambodia. A diagnostic comparison is made with Eugoa arida van Eecke, 1920, E. aridoides Holloway, 2001, E. grandipuncta Bucsek, 2008 and E. gracilisa Bucsek, 2008. Moreover, adult, male and female genitalia of E. arida van Eecke are illustrated for the first time. Illustration of adults, male and female genitalia of the new and closely allied species are presented.

Surfactant-free solubilization and systemic delivery of anti-cancer drug using low molecular weight methylcellulose.

Docetaxel, an advanced taxoid, has been widely used as an anti-mitotic agent, but further augmentation of its properties is still required, including improvement in low aqueous solubility. Herein, we report the development of bio-eliminable low molecular weight methylcellulose-based surfactant-free injectable formulation for the delivery of docetaxel. Crude methylcellulose, a hydrophobically modified cellulose derivative, was hydrolyzed by an enzymatic degradation method to obtain low molecular weight methylcellulose (LMwMC). Docetaxel was successfully loaded in micelles with small particle sizes high drug loading and sustained release profile. The in vivo anti-cancer effects of intravenously injected nanoparticle systems in B16F10 melanoma xenograft mice were evaluated and demonstrated a significantly enhanced therapeutic effect with the docetaxel-LMwMC micellar aggregates compared to a commercially available docetaxel, Taxotere®. Surfactant-free solubilization of docetaxel could be a promising delivery method for effective insoluble drug delivery for anti-tumor efficacy.