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1.
Genet Mol Res ; 13(3): 6878-84, 2014 Aug 29.
Article in English | MEDLINE | ID: mdl-25177967

ABSTRACT

We investigated the ultrasonic imaging characteristics of transplanted kidneys with delayed graft function (DGF). Ultrasonography was performed in 44 patients after kidney transplantation, and a time-intensity analysis was performed to compare the differences between patients with normal graft function (NGF) and those with DGF. Compared with the NGF group, the DGF group had earlier arrival time, shorter time to peak, and higher arrival intensity and peak intensity (P < 0.05). The variation-of-intensity parameters in different renal cortices increased, whereas the variation-of-time parameter decreased, in those with DGF (P < 0.05). In conclusion, compared with the NGF group, the microcirculation perfusion of transplanted kidneys in the DGF group showed higher perfusion with earlier arrival time, shorter time to peak, and higher arrival intensity and peak intensity. In addition, the intensity variations of contrast agent in different renal cortices from patients with DGF were greater, whereas the variations in perfusion time were smaller than those in patients with NGF.


Subject(s)
Delayed Graft Function/diagnostic imaging , Kidney Transplantation , Kidney/diagnostic imaging , Kidney/physiopathology , Adult , Delayed Graft Function/diagnosis , Female , Graft Rejection/diagnosis , Graft Rejection/diagnostic imaging , Humans , Male , Middle Aged , Sensitivity and Specificity , Time Factors , Ultrasonography
2.
Genet Mol Res ; 13(1): 1735-43, 2014 Mar 17.
Article in English | MEDLINE | ID: mdl-24535912

ABSTRACT

Parenchyma vascular malformation (VM) is a common disease in modern society. Here, we investigated the clinical effects and safety of interventional therapy (IT) on the treatment of parenchyma VM. From January 1998 to December 2010, 31 patients with VM who elected IT were investigated, including 11 cases of venous VM and 20 cases of arteriovenous malformation. There were 19 males and 12 females, ranging from 12 to 51 years in age. VM often occurred in the four limbs and other areas, such as the trunk and reproductive organs. Under the guidance of digital subtraction angiography, vascular hardener was injected into the VM spot via percutaneous puncture. Then, embolotherapy was conducted via the transcatheter feeding artery. We found that, in all cases, the malformed vessels were completely or partially blocked. After treatment, the local swelling of vessels was alleviated and the diabrosis and bleeding ceased. The soft tissue lump shrank, then stiffened and became fixed. There was no occurrence of severe intraoperative or postoperative complications in any patient. In summary, IT is an effective method for treating parenchyma VM, causes only a minor operative wound, and should be viewed as the first choice intervention.


Subject(s)
Mesophyll Cells/pathology , Vascular Malformations/therapy , Adult , Angiography, Digital Subtraction , Embolization, Therapeutic , Female , Humans , Male , Mesophyll Cells/diagnostic imaging , Middle Aged , Vascular Malformations/diagnostic imaging , Young Adult
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