ABSTRACT
An autopsy case of high-grade endometrial stromal sarcoma (ESS) is reported. Immunohistochemical study of the ESS was done in comparison with carcinosarcoma (CS), leiomyosarcoma (LMS) and normal endometrium in the uterus in order to trace the origin of ESS, which is a point of some controversy. Co-expression of keratin and vimentin and/or desmin positivity in several elements of CS and LMS, and glandular or stromal tissues in normal endometrium made it difficult immunohistochemically to be certain of the origin of ESS.
Subject(s)
Sarcoma/pathology , Uterine Neoplasms/pathology , Antigens/metabolism , Antigens, Differentiation/metabolism , Autopsy , CD57 Antigens , Carcinosarcoma/metabolism , Carcinosarcoma/pathology , Desmin/immunology , Endometrium/cytology , Endometrium/metabolism , Endometrium/pathology , Female , Humans , Immunohistochemistry , Keratins/immunology , Leiomyosarcoma/metabolism , Leiomyosarcoma/pathology , Middle Aged , Phosphopyruvate Hydratase/immunology , S100 Proteins/immunology , Sarcoma/metabolism , Uterine Neoplasms/metabolism , Vimentin/immunologyABSTRACT
It has been repeatedly stated that home monitoring of the intraocular pressure of glaucomatous patients could be of clinical significance. However, home tonometry has not been implemented due to the lack of an appropriate instrument. We present herein an upgraded version of a home tonometer that can be used by the patient alone. When it was tested on 37 eyes of 22 glaucomatous patients, the reproducibility was 1.7 mm Hg at IOPs of 20 mm Hg. The IOP was also measured with a Goldmann applanation tonometer. The two measurements were well correlated (r = .89) and the accuracy of the home tonometer, namely the variation of the data from the regression curve, was 2.5 mm Hg. This accuracy is compared with that of conventional tonometers. Moreover, the study showed that the home tonometer yielded reliable results in the hands of a substantial portion of the potential population.
Subject(s)
Self Care , Tonometry, Ocular , Adult , Aged , Evaluation Studies as Topic , Female , Humans , Male , Middle Aged , Tonometry, Ocular/instrumentationABSTRACT
Glaucomatous damage develops in certain patients because of elevated episcleral venous pressure (EVP). To measure the EVP in typical clinical settings, a practical and reliable instrument is needed. We have developed such an instrument, the venomanometer, and present tests of its reproducibility. The intraobserver reproducibility was 0.7 mm Hg, and the mean difference between the readings of two observers was 0.7 +/- 1.2 mm Hg. We then used the venomanometer to study the EVP in 122 eyes of 68 normal subjects distributed in seven age groups between 10 and 80 years. The EVP did not vary with age (mean, 7.6 +/- 1.3 mm Hg). This value is compared with those obtained with other instruments.
