ABSTRACT
Cytomorphological findings in the cerebrospinal fluid (CSF) of two patients suffering plasma cell leukemia and non Hodgkin's mixed cell lymphoma are reported. In the first were found immature plasma cells, polynucleate giant cells with giant nucleoli and atypical mitoses. In the second one polynucleate giant cells with hypercromatic and polyfissured nuclei and atypical mitoses are prominent. It is emphasized the importance of the early cytomorphological CSF study in patients with myelo or lymphoproliferative diseases.
Subject(s)
Cerebrospinal Fluid/cytology , Leukemia, Plasma Cell/cerebrospinal fluid , Lymphoma/cerebrospinal fluid , Meningeal Neoplasms/cerebrospinal fluid , Meninges/pathology , Cytodiagnosis , Humans , Leukemia, Plasma Cell/pathology , Lymphoma/pathology , Male , Meningeal Neoplasms/pathology , Middle AgedABSTRACT
Son presentadas las caracteristicas citomorfologicas anormales encontradas en el LCR de dos pacientes, uno de ellos sufriendo de leucemia aguda a celulas plasmaticas y otro de linfoma mixto no Hodgkin. Se enfatiza la importancia del estudio del LCR en estas patologias
Subject(s)
Leukemia, Plasma Cell , Lymphoma , MeningesSubject(s)
Blood Cells , Central Nervous System Diseases/cerebrospinal fluid , Cerebrospinal Fluid/cytology , Homeostasis , Adolescent , Adult , Aged , Cell Count , Central Nervous System Diseases/physiopathology , Cerebrospinal Fluid/physiology , Child , Child, Preschool , Humans , Infant , Lymphocytes , Middle Aged , Mitosis , Staining and LabelingABSTRACT
Six cases of meningeal melanomatosis are reported. The cytomorphological analysis of cerebrospinal fluid lead to diagnosis in all of them. Emphasis is given to morphological characteristics of the tumor cells and specially to the melanin dark brown pigment, observed in all cases here reported.