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1.
Biomolecules ; 14(6)2024 Jun 17.
Article in English | MEDLINE | ID: mdl-38927121

ABSTRACT

Zinc is an important trace element for growth and health at pediatric ages. Zinc is fundamental in inflammatory pathways, oxidative balance, and immune function. Zinc exhibits anti-inflammatory properties by modulating Nuclear Factor-kappa (NF-κB) activity and reducing histamine release from basophils, leukocytes, and mast cells. Furthermore, its antioxidant activity protects against oxidative damage and chronic diseases. Finally, zinc improves the ability to trigger effective immune responses against pathogens by contributing to the maturation of lymphocytes, the production of cytokines, and the regulation of apoptosis. Given these properties, zinc can be considered an adjunctive therapy in treating and preventing respiratory, nephrological, and gastrointestinal diseases, both acute and chronic. This review aims to deepen the role and metabolism of zinc, focusing on the role of supplementation in developed countries in pediatric diseases.


Subject(s)
Zinc , Humans , Zinc/metabolism , Zinc/therapeutic use , Child , Developed Countries , Dietary Supplements , Antioxidants/therapeutic use , Antioxidants/pharmacology , Antioxidants/metabolism , Anti-Inflammatory Agents/therapeutic use , Anti-Inflammatory Agents/pharmacology
2.
Biomedicines ; 12(4)2024 Apr 19.
Article in English | MEDLINE | ID: mdl-38672265

ABSTRACT

Nutrition management is fundamental for children with chronic kidney disease (CKD). Fluid balance and low-protein and low-sodium diets are the more stressed fields from a nutritional point of view. At the same time, the role of micronutrients is often underestimated. Starting from the causes that could lead to potential micronutrient deficiencies in these patients, this review considers all micronutrients that could be administered in CKD to improve the prognosis of this disease.

3.
Children (Basel) ; 10(11)2023 Oct 24.
Article in English | MEDLINE | ID: mdl-38002812

ABSTRACT

Cannabis, a plant known for its recreational use, has gained global attention due to its widespread use and addiction potential. Derived from the Cannabis sativa plant, it contains a rich array of phytochemicals concentrated in resin-rich trichomes. The main cannabinoids, delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD), interact with CB1 and CB2 receptors, influencing various physiological processes. Particularly concerning is its prevalence among adolescents, often driven by the need for social connection and anxiety alleviation. This paper provides a comprehensive overview of cannabis use, its effects, and potential health risks, especially in adolescent consumption. It covers short-term and long-term effects on different body systems and mental health and highlights the need for informed decision making and public health initiatives, particularly regarding adolescent cannabis use.

4.
J Environ Manage ; 248: 109313, 2019 Oct 15.
Article in English | MEDLINE | ID: mdl-31374434

ABSTRACT

End of life photovoltaic panels of different technologies (poly crystalline Si, amorphous Si, and CdTe) were treated mechanically in pilot scale by single shaft shredder minimizing the production of fine fractions below 0.4 mm (<18% weight). Grounded material was sieved giving: an intermediate fraction (0.4-1 mm) of directly recoverable glass (18% weight); a coarse fraction (which should be further treated for encapsulant removal), and fine fractions of low-value glass (18%), which can be treated by leaching for the removal of metal impurities. Encapsulant removal from coarse fraction was successfully performed by solvent treatment using cyclohexane at 50 °C for 1 h giving high-grade glass (52% weight), which can be reused for panel production. Experimental results of solvent treatment were compared with those from thermal treatment by economic analysis and Life Cycle Assessment, denoting in both cases the advantages of solvent treatment in recovering high-value glass.


Subject(s)
Cadmium Compounds , Quantum Dots , Tellurium , Glass , Recycling , Silicon , Solvents
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