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1.
Intern Med ; 56(19): 2639-2643, 2017 Oct 01.
Article in English | MEDLINE | ID: mdl-28883230

ABSTRACT

We herein report an uncommon case of a life-threatening retroperitoneal hematoma after a bone marrow biopsy. Two hours after iliac crest bone harvesting, the patient experienced syncope and severe hypotension. Urgent contrast-enhanced computed tomography demonstrated extravasation from the superior gluteal artery. Transcatheter coil embolization was performed successfully, without complications. Life-threatening complications caused by retroperitoneal bleeding after bone marrow biopsy are very rare. There are few reports on the use of endovascular treatment in the management of life-threatening hemorrhagic complications after bone marrow biopsy.


Subject(s)
Aorta, Abdominal/injuries , Aortic Rupture/etiology , Biopsy/adverse effects , Bone Marrow/pathology , Embolization, Therapeutic/methods , Hemorrhage/therapy , Iliac Artery/physiopathology , Adult , Aortic Rupture/physiopathology , Endovascular Procedures , Female , Hemorrhage/diagnostic imaging , Humans , Iatrogenic Disease , Iliac Artery/diagnostic imaging , Retroperitoneal Space , Treatment Outcome
2.
Ann Vasc Surg ; 44: 415.e11-415.e16, 2017 Oct.
Article in English | MEDLINE | ID: mdl-28483615

ABSTRACT

The antiphospholipid syndrome (APS), either primary or secondary form, is considered an autoimmune disease with the presence of at least 1 clinical and 1 laboratory abnormalities as defined by the Sydney criteria. Clinical criteria include vascular thrombosis of venous, artery, small vessel in any organ, and recurrent pregnancy pathologies. Mesenteric ischemia is a rare and threatening manifestation of APS. We herein report a case of a 34-year-old pregnant woman referred to our Emergency Room with thoracic and abdominal acute pain. Her past medical history was remarkable for positivity to antiphospholipid antibodies, deep vein thrombosis of the right lower limb, chronic occlusion of celiac trunk, and superior mesenteric artery and recurrent abortions. Imaging revealed acute occlusion of inferior mesenteric artery (IMA). Both a surgical and endovascular thrombectomy were ineffective to obtain durable IMA patency and so the patient underwent antegrade aorta-inferior mesenteric bypass with saphenous vein and resection of an ischemic ileal loop. The medical treatment at discharge was lifelong oral anticoagulant associated with double antiplatelet therapy. To the best of our knowledge, this is the first case reporting a young pregnant woman with APS and mesenteric ischemia submitted to several attempts of revascularization. Aggressive oral anticoagulant and antiplatelet long-term therapy is advised. Moreover, we recommend strict follow-up in those patients in order to early diagnose thrombotic recurrence.


Subject(s)
Antiphospholipid Syndrome/complications , Mesenteric Artery, Superior , Mesenteric Vascular Occlusion/etiology , Pregnancy Complications, Cardiovascular/etiology , Thrombosis/etiology , Adult , Angiography, Digital Subtraction , Anticoagulants/administration & dosage , Antiphospholipid Syndrome/blood , Antiphospholipid Syndrome/diagnosis , Antiphospholipid Syndrome/drug therapy , Computed Tomography Angiography , Female , Humans , Mesenteric Artery, Superior/diagnostic imaging , Mesenteric Artery, Superior/physiopathology , Mesenteric Artery, Superior/surgery , Mesenteric Ischemia/diagnostic imaging , Mesenteric Ischemia/etiology , Mesenteric Ischemia/physiopathology , Mesenteric Ischemia/surgery , Mesenteric Vascular Occlusion/diagnostic imaging , Mesenteric Vascular Occlusion/physiopathology , Mesenteric Vascular Occlusion/surgery , Pregnancy , Pregnancy Complications, Cardiovascular/diagnostic imaging , Pregnancy Complications, Cardiovascular/physiopathology , Pregnancy Complications, Cardiovascular/surgery , Saphenous Vein/transplantation , Severity of Illness Index , Splanchnic Circulation , Thrombosis/diagnostic imaging , Thrombosis/physiopathology , Thrombosis/surgery , Treatment Outcome , Vascular Grafting/methods
3.
Transl Med UniSa ; 6: 11-5, 2013.
Article in English | MEDLINE | ID: mdl-24251239

ABSTRACT

Between 1972 and 2012, 25 patients presenting 32 paragangliomas of the neck were observed. Tumor locations included the carotid body (CBTs) in 21 patients and the vagus nerve in 4. Four patients had bilateral CBT and one a bilateral vagal tumor; a metachronous bilateral jugulare paraganglioma was diagnosed in one patient with bilateral CBT Shamblin type III. Five patients presented CBTs type II and three type III. Preoperative embolization was performed in 5 CBTs, with no significant difference in blood loss. Twenty-nine paragangliomas were resected (with three internal carotid artery resection): there were no cerebrovascular accident or perioperative death. Nine patients (36%) had cranial nerve palsy prior to surgery and a postoperative nerve dysfunction occurred in four other tumors (16%). Persistent nerve deficits occurred in 3 patients (12%). No evidence of malignancy was shown, intraoperatively or during a postoperative follow-up period (9 months to 18 years; mean: 8 years).

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