Glued intraocular lens implantation: A three-year retrospective analysis at two hospitals in Brussels, Belgium.

PURPOSE: To analyze the outcomes and refraction of cases receiving fibrin glue-assisted posterior chamber intraocular lens implantation (Glued IOL) from December 2014 to December 2017 at Saint-Pierre Hospital and Saint-Anne Hospital in Brussels. METHODS: Multicenter retrospective descriptive observational study of consecutive cases that underwent glued intraocular lens implantation from December 2014 to December 2017 at Saint-Pierre Hospital and Saint-Anne Hospital in Brussels. The purpose is to analyze the results preoperatively and 3months postoperatively, the postoperative intraocular pressure, the reasons that led us to use this surgical technique, the immediate and late complications and finally the astigmatism and refraction before and after the surgery. RESULTS: A total of 33 eyes were evaluated. Among the indications, 42.42% were intraoperative posterior capsular rupture, 33.3% were dislocated IOL and 12% were (sub) luxated cataract. The mean preoperative and postoperative intraocular pressure was 17.1mmHg and 16.3mmHg, respectively. There were no intraoperative complications, but there were 5 postoperative complications, one macular cystoid edema, one hyphema, one retinal detachment and 2 haptic extrusions. The mean corneal astigmatism pre- and postoperatively was 1.43 and 1.49 diopters, respectively. The postoperative spherical equivalent refractions were between -0.75 and +0.75 D.

Vitrectomy in uveitis patients.

PURPOSE: To evaluate the causes and success rates of pars plana vitrectomy (PPV) in uveitis patients. METHODS: Retrospective study of the charts of 26 uveitis patients (28 eyes) who underwent PPV between the years 2008 and 2011. We examined surgical indications and success rates, based on visual outcomes, complications and diagnosis in case of vitreous biopsy. RESULTS: (1) Therapeutic PPV (TV) was performed in 36% of the eyes, (2) TV combined with epiretinal membrane (ERM) peeling in 21% and (3) diagnostic PPV (DiV) was performed in 64% of the eyes. Eight eyes (28,6%) underwent a combined cataract and vitreous surgery. Visual acuity (VA) improved in 16 eyes (57%), with a mean improvement of -0,9 log of the minimum angle of resolution (logMAR), although the effect was transient in 7% of the cases. VA remained stable in 11 eyes (39%) and decreased in 1 (4%). Post-operative complications were cystic macular oedema (CMO) in 3 eyes (11%), cataract in 5 eyes (18%) and retinal detachment in 2 eyes (7%). Diagnostic tests were performed in 18 eyes with a success rate of 55%. CONCLUSIONS: In our series of patients with uveitis, a good andstable improvement of VA was found when PPV was performed with ERM peeling while the effect on VA was more transient in the other cases. A good success rate of diagnosis was also found in DiV. However, considering the possible severe complications, diagnostic vitrectomy should be limited to selected cases.

Herpes zoster ophthalmicus complicated by complete ophthalmoplegia and signs of pilocarpine hypersensitivity. A case report and literature review.

We report a case of zona ophthalmica complicated with a complete ophthalmoplegia. In the literature only 19 cases have been reported the last 30 years, with a variety of possible pathophysiological mechanisms. Our patient's mydriasis reacted to diluted pilocarpine 0.125% which is a sign of Adie's pupil and is not supposed to occur in mydriasis caused by a third nerve palsy. We review the literature on the possible pathogenesis of this hypersensitivity.

Disposable devices for the dispensing of oral drops. Study of photoprotectiveness and compatibility.

Amber-coloured syringes designed for the distribution of unit-doses of oral drops were studied for the efficiency of the photoprotectiveness and the possible binding of eleven phenothiazine neuroleptics: alimemazine, chlorpromazine, cyamemazine, fluphenazine, levomepromazine, periciazine, pipotiazine, prochlorperazine, thioproperazine, thioridazine, and trifluoperazine, all very easily oxidized in solution in daylight. Spectrofluorimetry made it possible, in one operation, to determine the remaining concentrations of drugs after storage and to verify the absence of photo-oxidation. The storage was performed up to 13 days at 25 +/- 3 degrees C and without any precaution from daylight. All the drugs studied were stable and none bound on the syringes. However, the stability appeared to be due to the antioxidants in the drug preparations, and not to the coloured material, since oral drops were also stable in uncoloured syringes designed for injection. Nevertheless, the amber-coloured syringes efficiently protect the active principles in pure aqueous solutions, without preservative, and thus this physical protection reinforces the chemical one of the galenical formulation.