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1.
Med J Malaysia ; 67(1): 81-6, 2012 Feb.
Article in English | MEDLINE | ID: mdl-22582554

ABSTRACT

Sensorineural hearing loss is a common and important source of disability among the workers and often caused by occupational noise exposure. Aims of the study were to determine the prevalence and contributing factors of hearing loss among airport workers. A cross-sectional study was carried out at an airport in Malaysia. This study used stratified sampling method that involved 358 workers who were working in 3 different units between November 2008 and March 2009. Data for this study were collected by using questionnaires eliciting sociodemographic, occupational exposure history (previous and present), life-style including smoking habits and health-related data. Otoscopic and pure-tone audiometric tests were conducted for hearing assessment. Noise exposure status was categorize by using a noise logging dosimeter to obtain 8-hour Time-Weighted Average (TWA). Data was analyzed by using SPSS version 12.0.1 and EpiInfo 6.04. The prevalence of hearing loss was 33.5%. Age >40 years old (aOR 4.3, 95%CI 2.2-8.3) is the main risk factors for hearing loss followed by duration of noise exposure >5 years (aOR 2.5, 95%CI 1.4-4.7), smoking (aOR 2.1, 95%CI 1.2-3.4), duration of service >5 years (aOR 2.1, 95%CI 1.1-3.9), exposure to explosion (aOR 6.1, 95%CI 1.3-29.8), exposure to vibration (aOR 2.2, 95%CI 1.1-4.3) and working in engineering unit (aOR 5.9, 95%CI 1.1-30.9). The prevalence rate ratio of hearing loss for nonsmokers aged 40 years old and younger, smokers aged 40 years old and younger, non-smokers older than 40 years old and smokers older than 40 years old was 1.0, 1.7, 2.8 and 4.6 respectively. This result contributes towards better understanding of risk factors for hearing loss, which is relatively common among Malaysian workers.


Subject(s)
Airports , Hearing Loss, Noise-Induced/etiology , Occupational Diseases/etiology , Adult , Age Factors , Cross-Sectional Studies , Female , Hearing Loss, Noise-Induced/epidemiology , Humans , Logistic Models , Malaysia , Male , Middle Aged , Occupational Diseases/epidemiology , Prevalence , Smoking/adverse effects
2.
Int J Tuberc Lung Dis ; 16(2): 163-8, 2012 Feb.
Article in English | MEDLINE | ID: mdl-22236915

ABSTRACT

BACKGROUND: Serial testing for tuberculosis (TB) exposure has been advocated among health care workers (HCWs) at risk of nosocomial infection. OBJECTIVE: To determine the incidence and factors associated with TB infection among selected HCWs in Malaysia and to determine interferon-gamma response in serial testing. DESIGN: A cohort of 769 HCWs were retested after 1 year using QuantiFERON®-TB Gold In-Tube. Incidence of TB infection was determined among HCWs who previously tested negative. Conversion and reversion rates using several definitions were explored. RESULTS: Incidence of TB infection was 9.9 per 100 workers per year (95%CI 7.9-12.3). Working in the Emergency Department (ED; RR 2.18, 95%CI 1.07-4.43) was significantly associated with risk of TB infection. Reversion and conversion occurred frequently, with 46.7% reversion among HCWs with baseline interferon-gamma (IFN-γ) levels of 0.35-0.70 international units (IU)/ml, and 23.8% conversion among HCWs with baseline IFN-γ levels of 0.20-0.34 IU/ml. CONCLUSIONS: TB infection control measures need to be strengthened, particularly in the ED, as the incidence of TB was high. Conversion and reversion rates in serial testing were high, and further studies are needed to facilitate its interpretation.


Subject(s)
Health Personnel/statistics & numerical data , Interferon-gamma/blood , Mass Screening/methods , Reagent Kits, Diagnostic , Tuberculin Test/instrumentation , Tuberculosis/epidemiology , Adult , Cross Infection/blood , Cross Infection/diagnosis , Cross Infection/epidemiology , Cross-Sectional Studies , Female , Follow-Up Studies , Humans , Incidence , Malaysia/epidemiology , Male , Retrospective Studies , Risk Factors , Time Factors , Tuberculosis/blood , Tuberculosis/diagnosis
3.
Med J Malaysia ; 67(5): 506-17, 2012 Oct.
Article in English | MEDLINE | ID: mdl-23770869

ABSTRACT

INTRODUCTION: This study focuses on sexual harassment, a form of psycological hazard that female registered nurses face throughout their day to day routine. The objective of this study is to find the prevalence of sexual harassment among female registered nurses working in government hospitals in Melaka, Malaysia and factors affecting them. METHODS: This is a cross sectional study conducted on 455 female registered nurses who have worked more than one year in the present 3 government hospitals in Melaka, Malaysia. A validated and pre tested questionnaires were given for the respondents to answer. Before respondents answer the questionaires, they are required to read the definition and the forms of sexual harassment provided. This is to help them to understand the correct definition and forms of sexual harassment that they could have experienced. The researcher is available during the distribution of the questionnaires and the respondents are free to ask the researcher anything that they do not understand about it. RESULTS: The results of this study show that the prevalence of sexual harassment among these nurses was 51.2% with the past one year incidence recorded at 22.8%. The most common forms of sexual harassment were verbal (46.6% ), visual (24.8% ), psycological (20.9%), physical (20.7%) and non -verbal (16.7% ). The study showed that 74.7% of the victims suffered from psychological effects brought upon by their encounter with various types of sexual harrasement at work. The study also found that the victims' self-perception of their physicality was a contributing factor to the prevalance of this situation. Those who were pretty, with attractive body figure, a friendly character and easy going had a higher prevalence of sexual harassment in the workplace. Meanwhile, those who were strict, and those who had a fierce character were not prone to sexual harassment. CONCLUSION: The prevalence of sexual harassment among registered nurses in the workplace found in this study was high and self-perception profile of the victims of sexual harassment was the main contributing factor to the problem. Sexual harassment in the workplace should not be taken lightly because the resulting effects was not only felt by the victims, but also by their family members, colleagues and patients under their care. Hence, steps should be taken by the hospital managements to manage and prevent this problem from occuring again in the future.


Subject(s)
Sexual Harassment , Surveys and Questionnaires , Cross-Sectional Studies , Government , Humans , Malaysia , Prevalence
4.
Med J Malaysia ; 64(3): 197-204, 2009 Sep.
Article in English | MEDLINE | ID: mdl-20527267

ABSTRACT

A cross sectional study was conducted among military armoured vehicle drivers in the two largest mechanized battalions with the objective to determine the prevalence of low back pain (LBP), and its association with whole body vibration (WBV) and other associated factors. A self-administered questionnaire and Human Vibration Meter were used in this study. A total of 159 respondents participated in this study and 102 (64.2%) of them were subjected to WBV measurement. One-hundred-and-seventeen respondents complained of LBP for the past 12 months giving a prevalence of 73.6%. The prevalence of LBP among tracked armoured vehicle drivers was higher (81.7%) as compared to wheeled armoured vehicle drivers (67.0%). The mean acceleration at Z-axis in tracked armoured vehicles (1.09 +/- 0.26 ms(-2)) and wheeled armoured vehicles (0.33 +/- 0.07 ms) were the dominant vibration directions. The mean estimated vibration dose value (eVDV) for eight-hour daily exposure at Z-axis (19.86 +/- 4.72 ms(-1.75)) in tracked armoured vehicles showed the highest estimation. Based on the European Vibration Directive (2002), the mean eVDV at Z-axis in tracked armoured vehicles exceeded exposure action value (EAV) (> 9.1 ms(-1.75), but did not exceed exposure limit value (ELV) (<21.0 ms(-1.75)). Logistic regression analysis revealed that only driving in forward bending sitting posture (OR = 3.63, 95% CI 1.06-12.42) and WBV exposure at X-axis (OR = 1.94, 95% CI 1.02-3.69) were significant risk factors to LBP. Preventive measures should be implemented to minimize risk of WBV and to improve ergonomic postures among drivers.


Subject(s)
Automobile Driving , Low Back Pain/etiology , Military Personnel , Occupational Diseases/etiology , Vibration/adverse effects , Adult , Cross-Sectional Studies , Humans , Logistic Models , Low Back Pain/epidemiology , Malaysia/epidemiology , Male , Middle Aged , Occupational Diseases/epidemiology , Prevalence , Risk Factors , Surveys and Questionnaires
5.
Environ Res ; 102(1): 9-12, 2006 Sep.
Article in English | MEDLINE | ID: mdl-16782088

ABSTRACT

Worldwide prohibitions on lead gasoline additives were a major international public health accomplishment, the results of which are still being documented in parts of the world. Although the need to remove lead from paints has been recognized for over a century, evidence reported in this article indicates that lead-based paints for household use, some containing more than 10% lead, are readily available for purchase in some of the largest countries in the world. Sixty-six percent of new paint samples from China, India, and Malaysia were found to contain 5000 ppm (0.5%) or more of lead, the US definition of lead-based paint in existing housing, and 78% contained 600 ppm (0.06%) or more, the limit for new paints. In contrast, the comparable levels in a nearby developed country, Singapore, were 0% and 9%. In examining lead levels in paints of the same brands purchased in different countries, it was found that some brands had lead-based paints in one of the countries and paints meeting US limits in another; another had lead-free paint available in all countries where samples were obtained. Lead-based paints have already poisoned millions of children and likely will cause similar damage in the future as paint use increases as countries in Asia and elsewhere continue their rapid development. The ready availability of lead-based paints documented in this article provides stark evidence of the urgent need for efforts to accomplish an effective worldwide ban on the use of lead in paint.


Subject(s)
Environmental Exposure , Environmental Pollutants/analysis , Lead Poisoning/prevention & control , Lead/analysis , Paint/analysis , China , Humans , India , Malaysia , Singapore , Spectrophotometry, Atomic
6.
Med J Malaysia ; 61(5): 647-50, 2006 Dec.
Article in English | MEDLINE | ID: mdl-17623973

ABSTRACT

Underwater and Hyperbaric Medicine is a treatment modality gaining recognition in Malaysia. It uses the hyperbaric oxygen therapy (HBOT) approach where patients are placed in recompression chambers and subjected to oxygen therapy under pressure. In Malaysia it was introduced as early as the 1960's by the Royal Malaysian Navy to treat their divers for decompression illness (DCI), arterial gas embolism (AGE) and barotraumas. Other sectors in the armed forces, universities and private health centres began developing this approach too in the late 1990's, for similar purposes. In 1996, Underwater and Hyperbaric Medicine began gaining its popularity when the Institute of Underwater and Hyperbaric Medicine at the Armed Forces Hospital in Lumut started treating specific clinical diseases such as diabetic foot ulcers, osteomyelitis, and carbon monoxide poisoning and other diseases using HBOT. This paper discusses the development of this interesting treatment modality, giving a brief historical overview to its current development, as well as provides some thought for its future development in Malaysia.


Subject(s)
Decompression Sickness/therapy , Decompression , Diving/adverse effects , Hyperbaric Oxygenation , Humans , Malaysia , Naval Medicine
7.
Med J Malaysia ; 59(2): 242-51, 2004 Jun.
Article in English | MEDLINE | ID: mdl-15559176

ABSTRACT

Job dissatisfaction in doctors and teachers is known to have direct consequences on the quality of service and teaching for patients and students respectively. A cross-sectional study to assess dissatisfaction in lecturers of School of Medical Sciences, Universiti Sains Malaysia (USM) and Faculty of Medicine, Universiti Kebangsaan Malaysia (UKM) was undertaken between August 2001 and May 2002. The original English version of the Job Content Questionnaire (CQ) version 1.7 (revised 1997) by Robert Karasek was self-administered to 73 (response rate 58.4%) and 80 (response rate 41.7%) lecturers in the medical faculties of USM and UKM, respectively. The prevalence of job dissatisfaction in USM and UKM lecturers were 42.6% and 42.9%, respectively; the difference was not significant (p>0.05). Risk factors of job dissatisfaction in USM lecturers were decision authority (p<0.001) and psychological job demand (p<0.001). Significant risk factors of job dissatisfaction in UKM lecturers were skill discretion (p<0.01) and psychological job demand (p<0.001). We conclude that psychological job demand was a risk factor of job dissatisfaction in both USM and UKM lecturers; in USM, decision authority was protective, while in UKM, skill discretion was protective against job dissatisfaction.


Subject(s)
Faculty, Medical/statistics & numerical data , Job Satisfaction , Teaching , Adult , Cross-Sectional Studies , Education, Medical, Undergraduate , Female , Humans , Linear Models , Malaysia , Male , Prevalence , Risk Factors , Surveys and Questionnaires
8.
Article in English | MEDLINE | ID: mdl-15272771

ABSTRACT

Job stress has now become one of the most significant health and safety issues in the workplace and one of the least understood areas of organizational cost. A cross-sectional study to assess job strain and dissatisfaction in lecturers of the School of Medical Sciences, Universiti Sains Malaysia (USM) was undertaken between August 2001 and May 2002. The original English version of the Job Content Questionnaire (JCQ) version 1.7 (revised 1997) by Robert Karasek was self-administered to 73 (response rate 58.4%) lecturers in School of Medical Sciences USM. The prevalence of job strain (defined by low decision latitude and high psychological demands) in USM was 23.3%. The risk factors of job strain in the lecturers were psychological stressors (adjusted OR 1.2, 95% CI 1.0, 1.4), created skill (adjusted OR 0.4, 95% CI 0.2, 0.8) and working in clinical-based departments (adjusted OR 18.7, 95% CI 1.6, 22.7). The prevalence of job dissatisfaction was 42.6%. Associated factors of job dissatisfaction in USM lecturers were decision authority (p < 0.001) and psychological job demand (p < 0.001). We conclude that psychological stressors and created skill were non-protective and protective, respectively, against job strain in USM lecturers. Clinical-based lecturers experienced higher job strain compared to non-clinical-based lecturers. Psychological job demand was strongly associated with job dissatisfaction, and decision authority was protective against job dissatisfaction.


Subject(s)
Faculty, Medical/statistics & numerical data , Job Satisfaction , Occupational Health , Stress, Psychological/epidemiology , Workload , Adult , Confidence Intervals , Cross-Sectional Studies , Female , Humans , Incidence , Malaysia/epidemiology , Male , Middle Aged , Odds Ratio , Probability , Risk Assessment , Schools, Medical , Surveys and Questionnaires , Teaching/standards , Teaching/trends
9.
Asia Pac J Public Health ; 16(1): 32-40, 2004.
Article in English | MEDLINE | ID: mdl-18839865

ABSTRACT

A cross-sectional study to assess job strain and its associated factors among lecturers of the School of Medical Sciences, Universiti Sains Malaysia (USM) and Faculty of Medicine, Universiti Kebangsaan Malaysia (UKM) was undertaken between August 2001 and May 2002. The original English version of the Job Content Questionnaire (JCQ) version 1.7 (revised 1997) by Robert Karasek based on the Job Strain Model was self-administered to 73 (response rate 58.4%) and 80 (response rate 41.7%) lecturers in the medical faculties of USM and UKM respectively. The prevalence of job strain (defined by low decision latitude and high psychological demand) in USM and UKM was 23.3% and 17.5%, respectively; the difference was not significant (p 2 0.05). Analysis showed that the associated factors of job strain in USM lecturers were psychological stressors (adjusted OR 1.2, 95% CI: 1.0, 1.4), created skill (adjusted OR 0.4, 95% CI: 0.2, 0.8), working in clinical-based departments (adjusted OR 18.9, 95% CI: 1.6, 22.7). The risk factors of job strain in UKM lecturers were created skill (adjusted OR 0.3, 95% CI: 0.1, 0.9), psychological stressors (adjusted OR 1.2, 95% CI: 1.0, 1.5) and co-worker support (adjusted OR 0.3, 95% CI: 0.1, 0.9). We conclude psychological stressors and created skill were nonprotective and protective, respectively, against job strain in both USM and UKM lecturers.


Subject(s)
Faculty, Medical , Occupational Exposure , Schools, Medical , Stress, Psychological , Adult , Cross-Sectional Studies , Female , Humans , Malaysia/epidemiology , Male , Stress, Psychological/epidemiology , Stress, Psychological/etiology
10.
Occup Environ Med ; 60(4): 262-70, 2003 Apr.
Article in English | MEDLINE | ID: mdl-12660374

ABSTRACT

AIMS: To determine the relation between sick leave and selected exposure variables among women semiconductor workers. METHODS: This was a cross sectional survey of production workers from 18 semiconductor factories. Those selected had to be women, direct production operators up to the level of line leader, and Malaysian citizens. Sick leave and exposure to physical and chemical hazards were determined by self reporting. Three sick leave variables were used; number of sick leave days taken in the past year was the variable of interest in logistic regression models where the effects of age, marital status, work task, work schedule, work section, and duration of work in factory and work section were also explored. RESULTS: Marital status was strongly linked to the taking of sick leave. Age, work schedule, and duration of work in the factory were significant confounders only in certain cases. After adjusting for these confounders, chemical and physical exposures, with the exception of poor ventilation and smelling chemicals, showed no significant relation to the taking of sick leave within the past year. Work section was a good predictor for taking sick leave, as wafer polishing workers faced higher odds of taking sick leave for each of the three cut off points of seven days, three days, and not at all, while parts assembly workers also faced significantly higher odds of taking sick leave. CONCLUSION: In Malaysia, the wafer fabrication factories only carry out a limited portion of the work processes, in particular, wafer polishing and the processes immediately prior to and following it. This study, in showing higher illness rates for workers in wafer polishing compared to semiconductor assembly, has implications for the governmental policy of encouraging the setting up of wafer fabrication plants with the full range of work processes.


Subject(s)
Occupational Diseases/epidemiology , Occupational Exposure , Semiconductors , Sick Leave/statistics & numerical data , Adult , Age Distribution , Cross-Sectional Studies , Female , Humans , Irritants/adverse effects , Logistic Models , Malaysia/epidemiology , Marital Status , Middle Aged , Occupational Diseases/etiology , Occupational Exposure/statistics & numerical data , Odds Ratio , Risk Factors
11.
Med J Malaysia ; 58(5): 653-6, 2003 Dec.
Article in English | MEDLINE | ID: mdl-15190649

ABSTRACT

How people perceive risk influences their behaviour towards these risks. We do not know how workers perceive risk of dying from diseases or accidents. This study was conducted among 198 workers of a security company in Malaysia. The workers were asked to score on a Likert scale of 1 to 5 the perceived risk of death of Malaysians from selected causes of death. The highest perceived risks of death were, in order of ranking, motor vehicle accidents, cancer and diabetes mellitus whereas according to the certified causes of death in Malaysia the highest risks of death among the selected items were cardiovascular disease, cancer and stroke. The difference in perception and mortality data needs be addressed.


Subject(s)
Attitude , Cause of Death , Adolescent , Adult , Aged , Female , Humans , Malaysia , Male , Middle Aged , Risk Factors
12.
Med J Malaysia ; 58(5): 657-66, 2003 Dec.
Article in English | MEDLINE | ID: mdl-15190650

ABSTRACT

A cross-sectional study to determine work-related musculoskeletal problems and ergonomic risk factors was conducted among 529 women semiconductor workers. Overall, 83.4% had musculoskeletal symptoms in the last one year. Pain in the back (57.8%), lower leg (48.4%) and shoulder (44.8%) were the three most common musculoskeletal problems. Significant associations were found between prolonged standing and upper and lower leg pain, between prolonged sitting and neck and shoulder pain and between prolonged bending and shoulder arm, back and upper leg pain. The study therefore showed a clear association between work-related musculoskeletal pain and prolonged hours spent in particular postures and movements.


Subject(s)
Musculoskeletal Diseases/epidemiology , Occupational Diseases/epidemiology , Adolescent , Adult , Ergonomics , Female , Humans , Middle Aged , Movement , Posture , Prevalence , Risk Factors , Semiconductors
13.
Med J Malaysia ; 58(3): 387-98, 2003 Aug.
Article in English | MEDLINE | ID: mdl-14750379

ABSTRACT

A study conducted between 1998-2001 on the semiconductor industry in Penang and Selangor found that irregular menstruation, dysmenorrhea and stress were identified as the three leading health problems by women workers from a checklist of 16 health problems. After adjusting for confounding factors, including age, working duration in current factory, and marital status, in a multiple logistic regression model, wafer polishing workers were found to experience significantly higher odds of experiencing irregular menstruation. Dysmenorrhea was found to be significantly associated with chemical usage and poor ventilation, while stress was found to be related to poor ventilation, noise and low temperatures.


Subject(s)
Occupational Exposure , Occupational Health , Semiconductors , Women, Working , Adult , Female , Humans , Malaysia
14.
Med J Malaysia ; 57(3): 340-7, 2002 Sep.
Article in English | MEDLINE | ID: mdl-12440274

ABSTRACT

A cross-sectional study was conducted to determine the prevalence and type of respiratory conditions including asbestos-related diseases among Malaysian asbestos cement workers. The study population consisted of 1164 workers who had undergone medical surveillance from 1995 to 1997, including full history, physical examination, chest radiography and spirometry. More than half the male workers were smokers or ex-smokers, with smokers having more respiratory symptoms and signs, and reduced FEV1 compared with non smokers. The five most common respiratory conditions diagnosed were bronchial asthma, chronic bronchitis, pulmonary tuberculosis, upper respiratory tract infections and allergic rhinitis. On follow-up, there were also two cases of asbestosis and one case of bronchial carcinoma. The asbestosis cases were probably related to heavy occupational exposure to asbestos fibres in the past, before governmental regulations were gazetted in 1986. Further follow-up is essential for continued monitoring of the health status of asbestos workers.


Subject(s)
Asbestos/adverse effects , Occupational Diseases/epidemiology , Occupational Diseases/etiology , Occupational Exposure/adverse effects , Respiratory Tract Diseases/epidemiology , Respiratory Tract Diseases/etiology , Adolescent , Adult , Female , Humans , Malaysia/epidemiology , Male , Middle Aged
15.
Med J Malaysia ; 56(1): 25-31, 2001 Mar.
Article in English | MEDLINE | ID: mdl-11503292

ABSTRACT

In 1997, the Ministry of Health Malaysia introduced a surveillance programme for occupational and work-related diseases including poisonings for cases seen in government health facilities. Between June 1997 and November 1998, there were 36 cases of respiratory disease and 95 cases of poisoning by chemicals and pesticides notified while skin diseases were 108 cases. Respiratory diseases reported were predominantly occupational asthma (25%), pneumoconiosis (17%) and infections (39%). The commonest reported skin disease was contact dermatitis (87%). The commonest causes of occupational poisonings were paraquat (19%), organo-phosphates (16%), agro-chemicals excluding pesticides (15%) and gases (10%). The number of cases reported is still relatively few compared to data from other countries, suggesting that there is still considerable under reporting.


Subject(s)
Occupational Diseases/epidemiology , Adult , Aged , Female , Humans , Lung Diseases/epidemiology , Malaysia/epidemiology , Male , Middle Aged , Poisoning/epidemiology , Skin Diseases/epidemiology , Time Factors
17.
Malays J Med Sci ; 7(2): 13-7, 2000 Jul.
Article in English | MEDLINE | ID: mdl-22977385

ABSTRACT

A cross sectional study was carried out to evaluate the extent of occupational health problems focusing on some aspects of musculoskeletal symptoms among batik workers in Kelantan, Malaysia. The workers selected must have been in that industry for at least one year. Using cluster sampling, 202 workers were selected from 21 factories. More than half (60.2%) of the workers had been troubled with musculoskeletal symptoms at work. The most common symptoms were pain over the shoulders (41.0%), lower back (34.4%) and ankle (34.4%). Duration of employment, younger age group, prolonged standing and awkward working task were among contributing factors. It is therefore necessary to improve on both ergonomic and psychosocial environments of batik workers in order to prevent these musculoskeletal symptoms.

18.
Med J Malaysia ; 54(3): 364-7, 1999 Sep.
Article in English | MEDLINE | ID: mdl-11045065

ABSTRACT

The first two cases of asbestosis in Malaysia are reported. Both had considerable occupational exposure to asbestos dust in the past, with a long latency period exceeding 30 years. One case presented with distinctive clinical and radiological features, while the other case was only confirmed by histological diagnosis. The usefulness of modern investigation techniques such as CT scan in the diagnosis of asbestosis is also illustrated.


Subject(s)
Asbestosis/epidemiology , Asbestosis/diagnostic imaging , Humans , Incidence , Malaysia , Male , Middle Aged , Radiography, Thoracic , Tomography, X-Ray Computed
19.
Am J Otolaryngol ; 19(4): 240-3, 1998.
Article in English | MEDLINE | ID: mdl-9692632

ABSTRACT

PURPOSE: To determine the combined effect of smoking and age on hearing impairment. MATERIALS AND METHODS: Pure tone audiometry test was conducted on 263 residents of a rural village who were not exposed to noise. The pack-years of smoking were computed from the subjects' smoking history. The association between pack-years and hearing impairment was assessed. The combined effect of smoking and age on hearing impairment was determined based on prevalence rate ratio. RESULTS: There was a statistically significant trend in the number of pack-years of smoking and age as risk factors for hearing impairment. The prevalence rates of hearing impairment for nonsmokers aged 40 years and younger, smokers aged 40 years and younger, nonsmokers older than 40 years of age, and smokers older than 40 years of age were 6.9%, 11.9%, 29.7%, and 51.3%, respectively. The prevalence rate ratio for nonsmokers aged 40 years and younger, smokers aged 40 years and younger, nonsmokers older than 40 years of age, and smokers older than 40 years of age (nonsmokers aged 40 years and younger as a reference group) was 1, 1.7, 4.3, and 7.5, respectively. The prevalence rate ratios showed a multiplicative effect of smoking and age on hearing impairment. CONCLUSION: Age and smoking are risk factors for hearing impairment. It is clear that smoking and age have multiplicative adverse effects on hearing impairment.


Subject(s)
Aging/physiology , Hearing Disorders/etiology , Smoking/adverse effects , Adolescent , Adult , Aged , Audiometry, Pure-Tone , Hearing Disorders/epidemiology , Humans , Linear Models , Malaysia/epidemiology , Male , Middle Aged , Prevalence , Risk Factors , Rural Population , Smoking/epidemiology
20.
Med J Malaysia ; 52(2): 117-23, 1997 Jun.
Article in English | MEDLINE | ID: mdl-10968068

ABSTRACT

This study aims to evaluate the practice of adjuvant chemotherapy in colorectal cancer at the Institute of Radiotherapy and Oncology, Hospital Kuala Lumpur. A retrospective analysis of 320 patients' records from 1986 to 1994 was carried out. Adjuvant chemotherapy was given to 98 patients. Cancers of the rectum and sigmoid colon constituted over 60% of the patients. All the regimes used were 5-fluorouracil-based. The oral route was the most commonly used (55.1%). Toxicity was seldom the reason for stopping treatment (2%). The adjuvant treatment employed has been tolerable while the survival was comparable with other centres.


Subject(s)
Colorectal Neoplasms/drug therapy , Adolescent , Adult , Aged , Chemotherapy, Adjuvant/adverse effects , Colorectal Neoplasms/mortality , Female , Fluorouracil/administration & dosage , Fluorouracil/adverse effects , Humans , Male , Middle Aged , Retrospective Studies
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