ABSTRACT
BACKGROUND: Several different crystalloid solutions are available for i.v. fluid administration but there is little information about their specific advantages and disadvantages. METHODS: We performed a systematic search of MEDLINE, EMBASE, and CENTRAL up until May 17, 2012, selecting all prospective human studies that directly compared any near-isotonic crystalloids and reported any outcome. RESULTS: From the 5060 articles retrieved in the search, only 28 met the selection criteria. There was considerable heterogeneity among the studies. Several articles reported an increased incidence of hyperchloraemic acidosis with the use of normal saline, and others an increase in blood lactate levels when large amounts of Ringer's lactate solutions were infused. From the limited data available, normal saline administration appears to be associated with increased blood loss and greater red blood cell transfusion volumes in high-risk populations compared to Ringer's lactate. Possible effects of the different solutions on renal function, inflammatory response, temperature, hepatic function, glucose metabolism, and splanchnic perfusion are also reported. The haemodynamic profiles of all the solutions were similar. CONCLUSIONS: Different solutions have different effects on acid-base status, electrolyte levels, coagulation, renal, and hepatic function. Whether these differences have clinical consequences remains unclear.
Subject(s)
Fluid Therapy/methods , Isotonic Solutions/therapeutic use , Acid-Base Equilibrium/drug effects , Animals , Blood Glucose/drug effects , Body Temperature/drug effects , C-Reactive Protein/drug effects , Crystalloid Solutions , Dogs , Humans , Infusions, Intravenous , Kidney/drug effects , Liver/drug effects , Prospective Studies , Ringer's Lactate , Sodium Chloride/therapeutic useABSTRACT
Resumen La rotura de la aorta, independientemente de su localización y etiología, es unaafección extremadamente grave que conduce a la muerte rápidamente. En el momento actualno hay consenso sobre si el tratamiento endovascular de la rotura de la aorta torácica descendentees superior al tratamiento quirúrgico convencional a medio y largo plazo. En esta serie,de 13 casos, describimos nuestra experiencia y evaluamos los resultados en pacientes tratadosde forma endoprotésica desde enero de 2005 hasta enero de 2009 (AU)
Abstract Aortic rupture, independently of its location and etiology, is an extremely seriouscondition that leads to death rapidly. There is currently no consensus on whether endovasculartreatment of the descending thoracic aortic rupture is superior to conventional surgical repair interms of mid-or long-terms outcome. We describe our experience with 13 patients from January2005 to January 2009 to evaluate the results in patients with descending thoracic aortic ruptureundergoing endoprosthetic management (AU)
Subject(s)
Humans , Aneurysm, Ruptured/surgery , Aortic Rupture/surgery , Angioplasty/methods , Aortic Aneurysm, Thoracic/complicationsABSTRACT
Aortic rupture, independently of its location and etiology, is an extremely serious condition that leads to death rapidly. There is currently no consensus on whether endovascular treatment of the descending thoracic aortic rupture is superior to conventional surgical repair in terms of mid-or long-terms outcome. We describe our experience with 13 patients from January 2005 to January 2009 to evaluate the results in patients with descending thoracic aortic rupture undergoing endoprosthetic management.