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Angew Chem Int Ed Engl ; 38(19): 2949-2951, 1999 Oct 04.
Article in English | MEDLINE | ID: mdl-10540403

ABSTRACT

Both oxidized and reduced glutathione (gamma-L-Glu-L-Cys-Gly) react with the anticancer complex [Pt(en)Cl(2)] to form the bicyclic complex illustrated (en=ethylenediamine). This unprecedented structure, which was determined from extensive NMR experiments, contains a ten-membered macrochelate ring.

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