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Ocul Immunol Inflamm ; 29(2): 399-402, 2021 Feb 17.
Article in English | MEDLINE | ID: mdl-31710513

ABSTRACT

Purpose: To report a case of cancer-associated retinophaty (CAR) treated with intravenous immunoglobulin (IGIV) and review the use of IGIV in the treatment of CARMethods: Case report: A 68-year-old woman, former smoker, presented with bilateral subacute decreased visual acuity with 1 month of evolution, without other symptoms. Clinical examination revealed retinal atrophy and a mild vitritis component. Treatment with corticosteroid and IGIV was initiated empirically with the stabilization of visual loss. Anti-recoverin antibodies tested positive and a small cell lung carcinoma was diagnosed. In a review of the literature, we found that only 12 cases of patients treated with intravenous immunoglobulins have been reported.Conclusions: the early use of IVIG could contribute to an improvement and/or stabilization of visual symptoms in this patient group due to its rapid effect and lower profile of adverse effects when administered with chemotherapy.


Subject(s)
Carcinoma, Small Cell/drug therapy , Immunoglobulins, Intravenous/therapeutic use , Lung Neoplasms/drug therapy , Paraneoplastic Syndromes, Ocular/drug therapy , Retina/diagnostic imaging , Retinal Diseases/drug therapy , Aged , Female , Fluorescein Angiography/methods , Fundus Oculi , Humans , Immunologic Factors/therapeutic use , Paraneoplastic Syndromes, Ocular/diagnosis , Retinal Diseases/diagnosis , Retinal Diseases/etiology , Tomography, Optical Coherence/methods
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