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1.
Kyobu Geka ; 77(5): 369-372, 2024 May.
Article Ja | MEDLINE | ID: mdl-38720607

An 81-year-old man underwent total arch replacement for thoracic aortic aneurysm 8 years ago and catheter ablation for paroxysmal atrial fibrillation 1 year ago. Transthoracic echocardiography revealed a mass in the right atrium, and the patient was admitted for close examination and treatment. Transesophageal echocardiography revealed a 23×17 mm large well-defined mass above the cavotricuspid isthmus. Two venous drainage cannulas were inserted directly to the superior vena cava and to the inferior vena cava via the right femoral vein, in order to avoid the direct contact with the right atrium prior to institution of cardiopulmonary bypass. The right atrial tumor was found attached to the cavotricuspid isthmus, and was resected together with the right atrial wall. Pathological examination showed myxomatous tissue. Postoperative course was uneventful. He was discharged 23 days after the operation.


Catheter Ablation , Heart Atria , Heart Neoplasms , Myxoma , Humans , Myxoma/surgery , Myxoma/diagnostic imaging , Male , Aged, 80 and over , Heart Neoplasms/surgery , Heart Neoplasms/diagnostic imaging , Heart Atria/surgery
2.
Kyobu Geka ; 77(2): 101-105, 2024 Feb.
Article Ja | MEDLINE | ID: mdl-38459858

A 75-year-old woman was diagnosed with type B acute aortic dissection 14 years ago and 3-channeled aortic dissection 7 years ago. She received total arch replacement 6 years ago and descending aortic replacement with double barrel anastomosis technique for distal anastomosis 5 years ago. Computed tomography( CT) revealed giant thyroid tumor and thoracoabdominal aortic aneurysm( 58 mm in diameter). She suffered from back pain during her follow-up period. CT revealed ruptured thoracoabdominal aortic aneurysm. First, the false lumen of descending aorta was closed by thoracic endovascular aortic repair, and then thoracoabdominal aortic replacement was performed uneventfully.


Aortic Aneurysm, Thoracic , Aortic Aneurysm, Thoracoabdominal , Aortic Dissection , Aortic Rupture , Blood Vessel Prosthesis Implantation , Endovascular Procedures , Humans , Female , Aged , Aortic Aneurysm, Thoracic/diagnostic imaging , Aortic Aneurysm, Thoracic/surgery , Aortic Dissection/diagnostic imaging , Aortic Dissection/surgery , Aorta/surgery , Aortic Rupture/diagnostic imaging , Aortic Rupture/surgery , Blood Vessel Prosthesis Implantation/methods , Anastomosis, Surgical , Treatment Outcome
3.
Kyobu Geka ; 76(13): 1127-1130, 2023 Dec.
Article Ja | MEDLINE | ID: mdl-38088078

An 97-year-old woman was diagnosed with complete atrioventricular block and underwent pacemaker implantation( PMI). Three days after the PMI, computed tomography revealed cardiac perforation and migration of the lead to the abdominal cavity. Surgical procedure through median sternotomy was performed, and the penetrated lead was removed. The holes of the right ventricle and diaphragm were repaired. Abdominal organ was not injured. She was discharged 14 days after the surgical procedure.


Heart Injuries , Pacemaker, Artificial , Female , Humans , Aged, 80 and over , Heart Ventricles/diagnostic imaging , Heart Ventricles/surgery , Diaphragm/diagnostic imaging , Diaphragm/surgery , Pacemaker, Artificial/adverse effects , Thorax , Heart Injuries/diagnostic imaging , Heart Injuries/etiology , Heart Injuries/surgery
4.
Kyobu Geka ; 76(11): 941-944, 2023 Oct.
Article Ja | MEDLINE | ID: mdl-38056952

An 85-year-old woman underwent aortic arch replacement and thoracic endovascular aortic repair (TEVAR) 5 years ago. She suffered from chest and back pain. Computed tomography (CT) demonstrated enlargement of the aortic aneurysm by a type Ⅲb endoleak. TEVAR was performed to close a type Ⅲb endoleak with a relining technique uneventfully. Intraoperative completion aortography and postoperative CT confirmed the disappearance of a type Ⅲb endoleak. She was discharged 27 days after the treatment.


Aortic Aneurysm, Thoracic , Blood Vessel Prosthesis Implantation , Endovascular Procedures , Female , Humans , Aged, 80 and over , Blood Vessel Prosthesis , Endoleak/diagnostic imaging , Endoleak/etiology , Endoleak/surgery , Blood Vessel Prosthesis Implantation/adverse effects , Blood Vessel Prosthesis Implantation/methods , Endovascular Aneurysm Repair , Stents , Aorta, Thoracic/diagnostic imaging , Aorta, Thoracic/surgery , Treatment Outcome , Endovascular Procedures/adverse effects , Endovascular Procedures/methods , Aortic Aneurysm, Thoracic/diagnostic imaging , Aortic Aneurysm, Thoracic/surgery , Retrospective Studies
5.
Kyobu Geka ; 76(12): 1025-1029, 2023 Nov.
Article Ja | MEDLINE | ID: mdl-38057981

An 82-year-old woman suddenly developed chest pain and apoplexy. Computed tomography (CT) showed acute type A aortic dissection, the true lumen in the brachicephalic artery was severely compressed by the faulse lumen. Pulsation in the either leg was not detected during induction of anesthesia. We evaluated the cerebral blood flow and lower extremity blood flow using near infrared spectroscopy (NIRS) during the operation, tissue oxygenation index (TOI) was continuously monitored during the operation. Cardiopulmonary bypass( CPB) was established by puncturing the true lumen in the ascending aorta and bicaval venous drainage. TOI was returned to normal range by CPB. Although the central repair (ascending aorta replacement) was performed, leg ischemia persisted. We performed ascending aorta-bifemoral bypass. After the operation, leg ischemia disappeared and CT revealed patency of the bypass graft. Postoperative course was uneventful without deterioration of neurological function. She was discharged 49 days after the operation.


Aortic Dissection , Leg , Female , Humans , Aged, 80 and over , Leg/blood supply , Aortic Dissection/complications , Aortic Dissection/diagnostic imaging , Aortic Dissection/surgery , Aorta/surgery , Ischemia/diagnostic imaging , Ischemia/etiology , Ischemia/surgery , Lower Extremity/surgery
6.
BMC Cardiovasc Disord ; 23(1): 436, 2023 09 01.
Article En | MEDLINE | ID: mdl-37658328

BACKGROUND: Recent guidelines state that improving the survival rate of patients with ruptured abdominal aortic aneurysm (rAAA) requires a protocol or algorithm for the emergency management of these patients. We aimed to investigate whether introducing a protocol treatment for rAAA improves clinical outcomes compared with the pre-protocol strategy. METHODS: At our institution, 92 patients treated for rAAA between June 2008 and August 2022 were retrospectively analyzed. In 2014, the protocol-based treatment was introduced comprising a transfer algorithm to shorten the time to proximal control, use of an endovascular occlusion balloon, strict indications for endovascular aortic aneurysm repair (EVAR) or open surgical repair, and perioperative care, including for abdominal compartment syndrome (ACS). Clinical outcomes were compared between the protocol and pre-protocol group, including operative status, all-cause mortality, and rAAA-related death at 30-day, in-hospital, and 1-year postoperative follow-ups. RESULTS: Overall, 52 and 40 patients received the protocol-based and pre-protocol treatments, respectively. EVAR was more frequently performed in the protocol group. The rate of achieving time to proximal control was significantly faster, and the transfusion volume was lower in the protocol group. ACS occurred more frequently in the protocol group with a higher EVAR. No difference was found in all-cause mortality between the two groups. The protocol group exhibited fewer rAAA-related deaths than the pre-protocol group during the following time points: 30 days (9.6% vs. 22.5%), during the hospital stay (11.5% vs. 30.0%), and 1 year (14.5% vs. 31.5%). CONCLUSIONS: The protocol-based treatment improved the survival rate of patients with rAAA.


Aortic Aneurysm, Abdominal , Aortic Rupture , Humans , Retrospective Studies , Algorithms , Aorta , Aortic Rupture/diagnostic imaging , Aortic Rupture/surgery , Aortic Aneurysm, Abdominal/diagnostic imaging , Aortic Aneurysm, Abdominal/surgery
7.
Kyobu Geka ; 76(9): 714-718, 2023 Sep.
Article Ja | MEDLINE | ID: mdl-37735732

A 53-year-old man presented to the emergency department with chest and back pain. Contrast-enhanced computed tomography( CT) revealed a Stanford type A acute aortic dissection with a pseudo-lumen occlusion. On the same day, the patient underwent emergent aortic arch replacement with frozen elephant trunk. When introducing cardiopulmonary bypass, arterial cannula was inserted into the right femoral artery. The day after surgery, swelling of the right lower leg appeared with CK and intramuscular compartment pressure elevation. Thus, the patient was diagnosed with compartment syndrome and decompressive fasciotomy was performed. Although there was no preoperative blood flow disturbance in the lower extremities on preoperative CT, lower limbs ischemia happened. Necrotic muscles in his right leg required debridement, but amputation was not needed. The patient was discharged unaided utilising orthotics on the day 120. In muscular, young male patients, care should be taken in the method of blood delivery.


Aortic Dissection , Compartment Syndromes , Humans , Male , Middle Aged , Compartment Syndromes/diagnostic imaging , Compartment Syndromes/etiology , Compartment Syndromes/surgery , Leg , Aortic Dissection/diagnostic imaging , Aortic Dissection/surgery , Cardiopulmonary Bypass , Femoral Artery/diagnostic imaging , Femoral Artery/surgery
8.
Kyobu Geka ; 76(5): 371-374, 2023 May.
Article Ja | MEDLINE | ID: mdl-37150917

A 76-year-old man had been under observation for nephrotic syndrome. He suffered from hypotension and transient loss of consciousness. He was diagnosed with thoracic aortic aneurysm and severe aortic valve stenosis. Ascending aorta replacement concomitant with aortic valve replacement was performed uneventfully. He was diagnosed with light chain amyloidosis by pathological examination of the resected ascending aorta. He was received referral treatment for amyloidosis.


Aortic Aneurysm, Thoracic , Aortic Aneurysm , Aortic Valve Stenosis , Male , Humans , Aged , Aortic Valve/diagnostic imaging , Aortic Valve/surgery , Aortic Aneurysm/surgery , Aorta/surgery , Aortic Aneurysm, Thoracic/diagnostic imaging , Aortic Aneurysm, Thoracic/surgery , Aortic Aneurysm, Thoracic/complications , Aortic Valve Stenosis/diagnostic imaging , Aortic Valve Stenosis/surgery , Aortic Valve Stenosis/complications
9.
Kyobu Geka ; 76(6): 481-485, 2023 Jun.
Article Ja | MEDLINE | ID: mdl-37258030

A 59-year-old woman was transferred to our hospital because of a sudden onset of chest and back pain. Computed tomography (CT) demonstrated Stanford type A acute aortic dissection with cardiac tamponade and right airway bleeding. Hemorrhage from ruptured false lumen extended along the pulmonary artery (PA), compression of the right PA were recognized due to hematoma surrounding the PA. An emergency operation was performed. The primary tear was located at the distal aortic arch, and total arch replacement with frozen elephant trunk was performed. During the operation, she had airway bleeding. The bleeding was thought to be due to the hematoma extending along the pulmonary artery. She was extubated 7th postopratively. She was discharged 44 days after the operation.


Aortic Aneurysm, Thoracic , Aortic Dissection , Blood Vessel Prosthesis Implantation , Female , Humans , Middle Aged , Aortic Aneurysm, Thoracic/complications , Aortic Aneurysm, Thoracic/diagnostic imaging , Aortic Aneurysm, Thoracic/surgery , Blood Vessel Prosthesis Implantation/methods , Aortic Dissection/complications , Aortic Dissection/diagnostic imaging , Aortic Dissection/surgery , Aorta, Thoracic/surgery , Hemorrhage/diagnostic imaging , Hemorrhage/etiology , Hemorrhage/surgery , Hematoma/surgery , Lung/surgery
10.
Kyobu Geka ; 76(3): 216-220, 2023 Mar.
Article Ja | MEDLINE | ID: mdl-36861279

A 73-year-old man underwent drug eluting stent (DES) implantation in the left anterior descending artery (LAD) 11 years ago and in the right coronary artery (RCA) 8 years ago. He suffered from chest tightness and was diagnosed with severe aortic valve stenosis. Perioperative coronary angiography revealed no significant stenosis and thrombotic occlusion of the DES. Five days before operation, antiplatelet therapy was discontinued. Aortic valve replacement was performed uneventfully. But he developed chest pain and transient loss of consciousness, electrocardiographic changes were observed on the 8th postoperative day. Emergency coronary angiography revealed thrombotic occlusion of the drug eluting stent in the RCA, despite the postoperative oral adoministration of warfarin and aspirin. Percutaneous catheter intervention (PCI) restored the stent patency. Dual antiplatelet therapy (DAPT) was initiated immediately after the PCI, and anticoagulation therapy with warfarin was continued. Clinical symptons of stent thrombosis disappeared immediately after the PCI. He was discharged 7 days after the PCI.


Drug-Eluting Stents , Percutaneous Coronary Intervention , Male , Humans , Aged , Aortic Valve/surgery , Drug-Eluting Stents/adverse effects , Percutaneous Coronary Intervention/adverse effects , Warfarin , Perioperative Period
11.
Kyobu Geka ; 76(2): 140-143, 2023 Feb.
Article Ja | MEDLINE | ID: mdl-36731849

An 86-year-old woman who suffered from cardiac tamponade due to acute Stanford type A aortic dissection was admitted to our hospital. An emergency operation was performed uneventfully. She suffered from abdominal pain 13 days after the operation. Computed tomography( CT) scan revealed pericholecystic fluid and unclear gallbladder wall, revealing acalculous necrotizing cholecystitis. We performed open cholecystectomy and abdominal cavity drainage. No gallstones were observed. She underwent intensive treatment. She was discharged without complications 44 days after the cholecystectomy.


Aortic Dissection , Gallbladder , Female , Humans , Aged , Aged, 80 and over , Aortic Dissection/diagnostic imaging , Aortic Dissection/surgery , Tomography, X-Ray Computed , Necrosis
12.
Surg Today ; 53(7): 845-854, 2023 Jul.
Article En | MEDLINE | ID: mdl-36436023

PURPOSE: To compare the characteristics of reimplantation (RI) using grafts with sinuses and remodeling (RM) with/without external suture annuloplasty using a pulsatile flow simulator. METHODS: Porcine aortic roots were obtained from an abattoir, and six models of RM and RI with sinuses were prepared. External suture annuloplasty (ESA) was performed in the RM models to decrease the root diameter to 22 mm (RM-AP22) and 18 mm (RM-AP18). Valve models were tested at mean pulsatile flow and aortic pressure of 5.0 L/min and 120/80 (100) mmHg, respectively, at 70 beats/min. The forward flow, regurgitation, leakage, backflow rates, valve-closing time, and mean and peak pressure gradient (p-PG) were evaluated. Root configurations were examined using micro-computed tomography (micro-CT). RESULTS: The backflow rate was larger in the RM models than in the RI models (RI: 8.56% ± 0.38% vs. RM: 12.64% ± 0.79%; p < 0.01). The RM-AP and RI models were comparable in terms of the forward flow, regurgitation, backflow rates, p-PG, and valve-closing time. The analysis using a micro-CT showed a larger dilatation of the sinus of the Valsalva in the RM groups than in the RI group (Valsalva: RI, 26.55 ± 0.40 mm vs. RM-AP22, 31.22 ± 0.55 mm [p < 0.05]; RM-AP18, 31.05 ± 0.85 mm [p < 0.05]). CONCLUSIONS: RM with ESA and RI with neo-sinuses showed comparable hemodynamics. ESA to RM reduced regurgitation.


Aortic Valve Insufficiency , Aortic Valve , Hemodynamics , Replantation , Animals , Aortic Valve/surgery , Aortic Valve Insufficiency/surgery , Pulsatile Flow , Swine , X-Ray Microtomography
13.
Kyobu Geka ; 75(13): 1103-1107, 2022 Dec.
Article Ja | MEDLINE | ID: mdl-36539227

A 78-years-old woman was referred to our institution for the treatment of right subclavian artery (SCA) aneurysm. She previously underwent total arch replacement via median sternotomy approach. Preoperative computed tomography revealed a 55 mm sized SCA aneurysm. Stent graft was inserted from brachiocephalic artery to right common carotid artery via the graft anastomosed. The orifice of the right SCA was covered with stent graft inserted into the right common carotid artery-brachiocephalic artery and the right SCA was occluded with coils distal to the aneurysm, carotid-SCA bypass was performed with 8 mm ePTFE graft. Postoperative examination confirmed complete exclusion of the aneurysm and patency of the bypass graft. We thought that hybrid treatment for this patient was a less invasive alternative to conventional surgical procedure.


Aneurysm , Blood Vessel Prosthesis Implantation , Female , Humans , Aged , Subclavian Artery/diagnostic imaging , Subclavian Artery/surgery , Aneurysm/diagnostic imaging , Aneurysm/surgery , Carotid Artery, Common/diagnostic imaging , Carotid Artery, Common/surgery , Stents , Tomography, X-Ray Computed , Blood Vessel Prosthesis Implantation/methods
14.
Kyobu Geka ; 75(12): 1014-1017, 2022 Nov.
Article Ja | MEDLINE | ID: mdl-36299155

A 76-year-old man with thoracic aortic aneurysm was admitted to our hospital. Aortic arch replacement was performed uneventfully. He suffered from abdominal pain 17 days after the operation. Computed tomography (CT) scan revealed a strangulated bowel obstruction, and we performed emergent open abdominal surgery. During the operation, we found an adhesion between the greater omentum and the retroperitoneum. The small intestine was intussuscepted into this site, and strangulated with necrosis of a 35-cm length. We performed a partial resection of the small intestine. We encountered rare strangulated bowel obstruction after open heart surgery due to adhesion of the great omentum in a patient without a history of abdominal surgery.


Aorta, Thoracic , Intestinal Obstruction , Male , Humans , Aged , Aorta, Thoracic/diagnostic imaging , Aorta, Thoracic/surgery , Intestinal Obstruction/diagnostic imaging , Intestinal Obstruction/etiology , Intestinal Obstruction/surgery , Internal Hernia , Intestine, Small/diagnostic imaging , Intestine, Small/surgery , Intestine, Small/pathology , Tissue Adhesions , Necrosis/etiology
15.
Kyobu Geka ; 75(11): 955-959, 2022 Oct.
Article Ja | MEDLINE | ID: mdl-36176257

A 84-year-old man was diagnosed with complete atrioventricular block and underwent pacemaker implantation( PMI). Two days after the PMI, chest X-ray revealed left pneumothorax, and a chest tube was inserted. The pneumothorax did not improve, and computed tomography revealed left lung injury by the right ventricular lead. Surgical procedure through median sternotomy was performed, and the penetrated lead was removed. The injured right ventricle and left lung were repaired. Ten days after the surgical procedure, intravenous implantation of new right ventricular lead was performed. He was discharged 38 days after the surgical procedure.


Heart Injuries , Lung Injury , Pacemaker, Artificial , Pneumothorax , Aged, 80 and over , Heart Injuries/diagnostic imaging , Heart Injuries/etiology , Heart Injuries/surgery , Humans , Lung , Lung Injury/diagnostic imaging , Lung Injury/etiology , Lung Injury/surgery , Male
16.
Kyobu Geka ; 75(8): 638-641, 2022 Aug.
Article Ja | MEDLINE | ID: mdl-35892305

A 73-year-old woman suffered from premature ventricular contraction( PVC) which could not be controlled by medications. Holter 24-hour continuous recording electrocardiogram (Holter ECG) revealed 22,706 PVC beats/day. Upon further examination, she was found to have severe aortic stenosis and mild insufficiency. Preoperative electro-physiological study and standard 12-lead electrocardiogram revealed that the PVC originated from myocardium under the left coronary cusp. Aortic valve replacement and intraoperative cryoablation were performed. Her postoperative course was uneventful, Holter ECG revealed 638 PVC beats/day. Clinical symptons of PVC disappeared immediately after surgery. She was discharged 19 days after the operation.


Heart Valve Prosthesis , Ventricular Premature Complexes , Aged , Female , Humans , Aortic Valve/surgery , Heart Ventricles , Ventricular Premature Complexes/surgery
17.
Kyobu Geka ; 75(6): 452-456, 2022 Jun.
Article Ja | MEDLINE | ID: mdl-35618691

A 36-year-old woman with severe aortic valve stenosis was admitted to our hospital. She had been diagnosed with antiphospholipid syndrome complicated with systemic lupus erythematosus (SLE) and had been taking prednisolone( 10 mg/day) for 22 years. As SLE patients with prolonged steroid use are known to be at risk of an aortic dissection and aneurysm, femoral artery was chosen for arterial perfusion to reduce a risk of aortic dissection. Aortic valve replacement was performed uneventfully, because the aorta was treated carefully during the operation. Negative microbial culture and pathological examination of the resected aortic valve demonstrated an atypical vegetation, the findings of which were typically characteristic of Libman-Sacks endocarditis in SLE. She was discharged without complications 23 days after the operation.


Aortic Dissection , Endocarditis , Heart Valve Prosthesis , Lupus Erythematosus, Systemic , Adult , Aortic Dissection/complications , Aortic Valve/diagnostic imaging , Aortic Valve/surgery , Endocarditis/complications , Female , Heart Valve Prosthesis/adverse effects , Humans , Lupus Erythematosus, Systemic/complications
18.
Int J Cardiol Heart Vasc ; 40: 101030, 2022 Jun.
Article En | MEDLINE | ID: mdl-35434259

Background: Limited studies have assessed the factors affecting prognosis in hemodialysis (HD) patients who undergo surgical aortic valve replacement with a bioprostheses (SAVR-BP). This study aimed to evaluate the outcomes of HD patients who had undergone SAVR-BP for aortic stenosis (AS) and identify the risk factors for mortality. Methods: This retrospective study included 57 HD patients who had undergone SAVR-BP for AS between July 2009 and December 2020. Multivariate logistic regression was used to predict factors associated with mid-term outcomes and death or survival. Kaplan - Meier curves were also generated for mid-term survival. Results: The in-hospital mortality rate was 8.8%, and the 5-year mortality rate was 42.1%. The independent predictors of 5-year mortality were preoperative age (hazard ratio [HR], 1.57; 95% confidence interval [CI], 1.175-2.083, p = 0.002), hyperlipidemia (HR, 0.02; 95% CI, 0.002-0.297, p = 0.004), left ventricular diastolic diameter (HR, 1.74; 95% CI, 1.142-2.649, p = 0.010), left ventricular systolic diameter (HR, 0.61; 95% CI, 0.392-0.939, p = 0.025), and Japan SCORE (HR, 1.28; 95% CI, 1.052-1.563, p = 0.014). The postoperative predictors included intensive care unit stay (HR, 1.11; 95% CI, 1.035-1.194, p = 0.004) and albumin level (HR, 0.38; 95% CI, 0.196-0.725, p = 0.003). Conclusions: The 5-year prognosis of HD patients undergoing SAVR may be improved by early diagnosis (before the occurrence of LV hypertrophy/enlargement) and nutritional management with oral intake to alleviate postoperative hypoalbuminemia.Registration number of clinical studies: UMIN000047410.

19.
Kyobu Geka ; 75(5): 387-391, 2022 May.
Article Ja | MEDLINE | ID: mdl-35474205

An 85-year-old man received simultaneous coronary artery bypass grafting (CABG) and the ascending aorta to bifemoral bypass with a Dacron graft 11 years ago. He suffered from intermittent claudication. Angiography demonstrated a localized stenosis in a non-anastomotic site, straight portion of the graft. He received percutaneous transluminal angioplasty. The right ankle-brachial pressure index (ABI) improved from 0.58 to 0.74 and left ABI improved from 0.52 to 0.71. One year later, intermittent claudication appeared again, right ABI decreased to 0.53 and left ABI decreased to 0.52. Computed tomography( CT) demonstrated restenosis at the same portion of the graft. A re-do operation was performed, stenotic portion was removed and replaced by a new ePTFE graft. No restenosis was seen three years after the second operation. We thought that repeated temporary compression of the graft might have led to a clot formation in the non-anastomotic site.


Aorta , Intermittent Claudication , Aged, 80 and over , Angioplasty , Aorta/diagnostic imaging , Aorta/surgery , Constriction, Pathologic/surgery , Coronary Artery Bypass , Humans , Male
20.
J Cardiol ; 80(2): 116-124, 2022 08.
Article En | MEDLINE | ID: mdl-35288000

BACKGROUND: Patients with acute coronary syndrome complicated with cardiogenic shock (ACS-CS) frequently require mechanical circulatory support. In addition to veno-arterial extracorporeal membrane oxygenation (VA-ECMO), use of the Impella® (ECpella) (Abiomed Inc., Danvers, MA, USA) heart pump may improve the prognosis of such patients. In this study, we compared the efficacy of VA-ECMO plus intra-aortic balloon pumping (ECMO-IABP) with that of the ECpella for add-on circulatory support of VA-ECMO. METHODS: Clinical outcomes of 64 patients with ACS-CS treated with ECMO-IABP (n = 41) or ECpella (n = 23) between January 2013 and April 2021 were retrospectively analyzed. The primary outcomes were 30-day and 365-day mortality. In addition, patients resuscitated after cardiopulmonary arrest (CPA) were evaluated separately. RESULTS: The ECpella group showed significantly lower mid-term mortality than the ECMO-IABP group [30-day mortality (39.1% vs 56.1%, respectively; p = 0.193) and 365-day mortality (43.5% vs 75.6%, respectively; p = 0.010)], with significantly higher rates of new hemodialysis and bleeding at the vascular access site. Also, among the limited number of patients resuscitated from CPA, mortality was significantly lower in the ECpella group than the ECMO-IABP group [30-day mortality (28.6% vs 65.4%, respectively; p = 0.026) and 365-day mortality (28.6% vs 84.6%, respectively; p < 0.001)]. Among the resuscitated patients, ECMO weaning period and the incidence of neurological complications were related to 30-day mortality; The incidence of neurological complications was related to 365-day mortality. The use of ECpella was strongly associated with both 30-day and 365-day survival. CONCLUSIONS: The ECpella heart pump may provide a survival advantage over ECMO-IABP in patients with ACS-CS.


Acute Coronary Syndrome , Extracorporeal Membrane Oxygenation , Heart-Assist Devices , Acute Coronary Syndrome/complications , Acute Coronary Syndrome/therapy , Extracorporeal Membrane Oxygenation/adverse effects , Heart-Assist Devices/adverse effects , Humans , Intra-Aortic Balloon Pumping/adverse effects , Retrospective Studies , Shock, Cardiogenic/etiology , Shock, Cardiogenic/therapy , Treatment Outcome
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