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Food Chem ; 148: 54-9, 2014 Apr 01.
Article in English | MEDLINE | ID: mdl-24262526

ABSTRACT

Dietary fibre (DF) obtained from Agave tequilana, which is rich in fructans and insoluble DF, and jamaica calyces (Hibiscus sabdariffa), which is rich in DF and phenolic compounds, were assessed as new potential functional ingredients using the hypercholesterolemic animal model. Wistar rats (200-250 g) were divided into 3 groups (n=8) and fed with cholesterol-rich diets supplemented with cellulose (CC, control), agave DF (ADF) or ADF with jamaica calyces (ADF-JC). After consuming the test diets for 5 weeks, weight gain in the ADF-JC group was significantly lower than in the other groups. The ADF and ADF-JC groups had a reduced concentration of cholesterol transporters in the caecum tissue, although no changes were observed in the plasma lipid profile. Both treatments improved the redox status by reducing the malondialdehyde serum levels and protein oxidative damage, compared to the CC group. DF from A. tequilana alone, or in combination with jamaica calyces, shows promising potential as a bioactive ingredient.


Subject(s)
Agave/metabolism , Body Weight , Dietary Fiber/metabolism , Hibiscus/metabolism , Hypercholesterolemia/diet therapy , Plant Preparations/metabolism , Agave/chemistry , Animals , Hibiscus/chemistry , Humans , Hypercholesterolemia/metabolism , Hypercholesterolemia/physiopathology , Male , Oxidation-Reduction , Rats , Rats, Wistar
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