Physiological sensation word usage in social anxiety disorder with and without comorbid depression.

BACKGROUND & OBJECTIVES: Social anxiety disorder (SAD) is characterized by a fear of showing anxiety symptoms, which may manifest in greater physiological sensation (PS) word usage, especially when describing their anxious experiences. However, the role of comorbid major depressive disorder (MDD) is unknown. Given blunted physiological arousal in MDD, the SAD only group (SAD) may use more PS words than the comorbid (COM) group with SAD and MDD when discussing anxious memories. Due to more severe symptomology, however, the COM group may use more PS words than the SAD group. We examined these competing hypotheses. METHODS: The SAD (n = 30), COM (n = 19), and control (CTL; n = 30) groups recalled their happiest, saddest, and most anxious events. The proportion of PS words was examined. RESULTS: The SAD group used significantly more PS words than the CTL group, whose PS words did not differ significantly from the COM group; the SAD group used marginally more PS words than the COM group. Anxious memories contained significantly more PS words than happiest and saddest memories. Happiest and saddest memories did not significantly differ in PS words. LIMITATIONS: The PS words list was created by the authors, and a LIWC dictionary was not used. CONCLUSIONS: Blunted physiological arousal in MDD may have contributed to lower PS word usage in the COM group than the SAD group. Understanding linguistic differences between these groups may provide clinicians with insight into these individuals' preoccupations with bodily sensations that may maintain or exacerbate symptoms of anxiety.

Treatment of double depression: A meta-analysis.

BACKGROUND: Double depression (DD), the co-existence of DSM-IV major depressive disorder (MDD) and dysthymia, is a poorly known and sparsely studied phenomenon. Nevertheless, it is prevalent in clinical samples of patients with depression. Thus, it is important to understand the efficacy of its treatment. METHODS: We conducted a meta-analysis of studies in which antidepressant medication was used to treat depression. Systematic searches in bibliographical databases resulted in 11 samples, including 775 patients that met inclusion criteria. RESULTS: The overall effect size indicating the differences in depressive symptoms before and after pharmacotherapy was 1.81 (95% CI: 1.47, 2.16), suggesting that individuals with depression exhibited a significant reduction in their depressive symptoms following treatment. Importantly, a moderation analysis indicated that a higher proportion of individuals with DD within a sample was associated with lower effect sizes. Publication bias did not pose a major threat to the stability of the findings. LIMITATIONS: High observed heterogeneity indicated substantial variability in effect sizes and elucidation of the potential moderators of treatment outcome was limited due to a paucity of relevant data. CONCLUSIONS: Pharmacotherapy seems to be effective in treating DD, but DD may be more difficult to treat than either MDD or dysthymia alone. More research specifically focusing on the treatment of DD with larger sample sizes using randomized control trials is needed to make a firm conclusion.