[Enterovirus meningitis in a child of one month in source of infection]. / Enterovirusnyi meningit u rebenka v vozraste odnogo mesyatsa v semeinom ochage.

OBJECTIVE: To describe a rare case of enterovirus disease with meningitis in an infant. MATERIAL AND METHODS: Summary of medical records of the child and his mother were used. RESULTS AND CONCLUSION: The medical history, characteristics of the clinical picture, the composition of the cerebrospinal fluid (CSF) for laboratory confirmed Coxsackie B1-6 with meningitis in the infant, aged 1 month, and his mother, 40 years old, the source of which were older children who had the infection in the form of a «minor illness¼, are presented. Enterovirus RNA was detected by PCR in pleocytosis 984/3 on the 4th (in a child) and cytosis 18/3 on the 5th day (in a mother) in the two-wave course of the disease. Data on clinical forms of enterovirus infection in children, aged 0-12 months, the frequency of cases and clinical signs of enterovirus meningitis in infants are considered.

[Features of clinical picture of Herpes zoster in infants]. / Osobennosti kliniki opoyasyvayushchego gerpesa u grudnykh detei.

OBJECTIVE: To study clinical characteristics of Herpes zoster in infants. MATERIAL AND METHODS: Children underwent routine clinical/neurological, and laboratory/instrumental examinations (composition of cerebrospinal fluid (CSF), the level of specific antibodies in the blood and CSF assessed by ELISA, MRI of the brain and cervical spine and spinal cord with contrast enhancement). RESULTS AND CONCLUSION: Two rare cases of disease are reported: 1) a 3-month girl with polymorphic rash appeared on the skin and monoparesis of the left hand, 2) a 5-month girl due to infection with the varicella-zoster (VZ) virus occurred intrauterine. The data on the frequency and interpretation of the genesis of motor disorders in patients with different localization of rashes are presented. The authors draw attention to the latent phase (interval between the primary infection of the fetus and reactivation of VD-viral infection with a picture of HZ), which was 10 months.

[A case of vaccine-associated paralytic poliomyelitis in an infant]. / Sluchai vaktsinoassotsiirovannogo paraliticheskogo poliomielita u rebenka.

AIM: To present the clinical history, vaccination status, features of the clinical picture, composition of the cerebrospinal fluid (CSF), results of laboratory and instrumental examinations of a patient with vaccine-associated paralytic poliomyelitis (VAPP). MATERIAL AND METHODS: In 2017, a child, aged 15 month, mistakenly vaccinated with the first dose of bivalent (types 1 & 3) polioviruses oral vaccine (OPV) was followed up. RESULTS AND CONCLUSION: Clinical parameters of VAPP in the recipient of OPV are considered. Clinical features of disease caused by wild poliovirus and VAPP are compared. The disease was characterized by sudden onset, recurrence, short (2-4 days) period of progression of paresis, persistent residual effects, CSF protein-cell dissociation. It is emphasized that the occurrence of VAPP cases reflects primarily immunization defects.

['Masks' of acute neuroinfections and markers of differencial diagnosis]. / 'Maski' ostrykh neiroinfektsii i markery differentsial'noi diagnostiki.

AIM: To compare thе medical history, clinical features, composition of cerebrospinal fluid (CSF), results of laboratory and instrumental examinations of patients with acute neuroinfections and differentiable diseases including a pseudoinflammatory variant of the acute stage of uncomplicated subarachnoid hemorrhage (SAH), consequences of traumatic brain injury (traumatic SAH, SAN combination with secondary purulent meningitis, posttraumatic nasal liquorrhea, intracerebral hematomas), abscesses and tumors of the brain, lymphoma with proven CNS. These diagnoses were mistakenly made to patients admitted to an infectious department. MATERIAL AND METHODS: Forty-six patients, aged from 18 to 83 years, hospitalized in the Department of neuroinfections and intensive care in 2010-2016 were examined. Conventional clinical neurological, laboratory, instrumental (including MRI) examinations of patients, comprehensive examination of CSF samples, the study of markers of inflammation (C - reactive protein, CSF lactate), immunophenotyping of CSF cells were performed. RESULTS AND CONCLUSION: The misdiagnosis can be explained by the overestimation of such symptoms as the acute (in most cases) onset of the disease with increased body temperature to febrile levels, presence of meningeal syndrome, disorders of consciousness and focal symptoms of varying severity. The authors showed the errors and difficulties in the diagnosis, the role and importance of an integrated, interdisciplinary approach taking into account history, clinical data, results of CSF study, conventional and special methods of laboratory and instrumental examination of patients.

Triboluminescence and crystal structure of the centrosymmetric complex [Tb(NO3 )2 (Acac)(Phen)2 ]·H2 O.

The atomic structure of crystals of the complex [Tb(NO3 )2 (Acac)(Phen)2 ]·H2 O, (AA - acetylacetonate anion, Phen - 1,10-phenanthroline) characterized by an intensive luminescence and triboluminescence has been determined by means of an X-ray structural analysis method. Centrosymmetric crystals have a monoclinic syngony: a = 11.2298(1), b = 9.6492(1), c = 13.2745(1) Å, ß = 101.290(1), space group P2/n, Z = 2, ρcalc = 1.790 g/cm3 . The crystal structure is represented by individual С29 Н25 N6 O9 Tb complexes linked through van der Waals interactions with clearly expressed cleavage planes. The Tb(III) atom coordination polyhedron reflects the state of a distorted square antiprism. The structural aspects of the suggested model of formation of the triboluminescent properties were considered and the role of the cleavage planes discussed. Copyright © 2016 John Wiley & Sons, Ltd.

[Rare forms of segmental exanthema in patients with Herpes zoster].

OBJECTIVE: To describe rare clinical cases of Herpes zoster with a rash appeared simultaneously in different segmental zones (zoster duplex unilateralis and zoster duplex bilateralis). MATERIAL AND METHODS: Brief details of medical histories of 3 patients are presented. RESULTS AND CONCLUSION: A very rare possibility of the complete fusion of bilateral exanthema on the same topographic level with the development of an entire zoster that confirm a historical name of the disease has been demonstrated. A mistaken translation of disease name into Russian as "lishai" is emphasized. Recommendations on the complex, stage-by-stage treatment of patients, including psychotherapeutic treatment of the pain syndrome, are presented.

[Brain and spine cord lesions caused by syphilis].

OBJECTIVE: To analyze clinical features of the nervous system damage in syphilis taking into account the changes in the content of cerebrospinal fluid and clinical/anatomical brain damages of the brain. METHODS: The study was based on the analysis of 47 case histories of patients hospitalized in 1995-2001. The group included 47 patients, aged from 17 to 60 years. RESULTS: Syphilitic meningitis, syphilitic meningoneuritis, syphilitic menongoencephalitis, syphilitic meningovasculitis, cerebral gummas, syphilitic meningomyelitis and mental changes caused by syphilis are reviewed. CONCLUSIONS: The pathogenesis of different clinical forms of syphilitic damages of the brain and terminological issues are discussed.

[A rare form of eczema in a patient with herpes zoster].

A rare clinical condition, herpes Zoster duplex bilateralis, is described. Because the erroneous definition of the disease as a lichen is widespread even in the system of advanced medical training, the importance of differentiation between the notions of herpes and lichen is emphasized.

[Documented case of recurrent herpes zoster]. / Dokumentirovannyi sluchai povtornogo zabolevaniia opoiasyvaiushchim gerpesom.

The paper presents a comparative description of the clinical picture of herpes zoster observed in a patient twice in 1989 and 1997. For its differential diagnosis with herpes simplex, emphasis is laid on a difference between the concepts "relapse" and "recurrence".