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2.
Sci Rep ; 14(1): 5341, 2024 03 04.
Article in English | MEDLINE | ID: mdl-38438514

ABSTRACT

To assess the long-term association between the residual renal volume and the progression of chronic kidney disease (CKD) in kidney donors following open or laparoscopic donor nephrectomy. A retrospective observational study involving 452 individuals who underwent open or laparoscopic donor nephrectomy at Ramathibodi Hospital, Bangkok, Thailand. The study spanned over a comprehensive 60-month monitoring period. Residual renal volume was determined through Computer Tomography. Patient characteristics, surgical techniques, donated kidney side, and estimated glomerular filtration rate (eGFR) were collected and analysed. In a multivariate analysis, a residual renal volume exceeding 50% of original volume is associated with an increased likelihood of developing CKD, with a hazard ratio (HR) of 1.675 (P < 0.05), and male gender has a hazard ratio (HR) of 4.013 (P < 0.001). Additionally, age is identified as a minor risk factor for developing CKD, with hazard ratio (HR) of 1.107 (P < 0.001). Higher residual renal volume, male gender, and older age were identified as independent risk factors for the development of CKD following open or laparoscopic donor nephrectomy during long-term follow-up.


Subject(s)
4-Butyrolactone/analogs & derivatives , Kidney , Renal Insufficiency, Chronic , Male , Humans , Thailand/epidemiology , Kidney/diagnostic imaging , Renal Insufficiency, Chronic/etiology , Risk Factors , Nephrectomy/adverse effects
3.
SAGE Open Med Case Rep ; 12: 2050313X241232278, 2024.
Article in English | MEDLINE | ID: mdl-38352822

ABSTRACT

Employing percutaneous nephrolithotomy to manage a complex renal calculus has always been challenging due to the blood transfusion requirement and the frequent necessity of using multiple access tracts. We report a novel treatment modality in the case of a 65-year-old male with a complex, large-volume renal calculus who was successfully treated by vacuum-assisted miniaturized endoscopic combined intrarenal surgery using the combination of a thulium fiber laser in retrograde fashion with a holmium:YAG laser in antegrade fashion. The kidney stone was entirely cleared, and the patient fully recovered with no adverse event.

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