An infrequent case of adult nasopharynx rhabdomyosarcoma with bony involvement: A case report.

Rhabdomyosarcoma is a rare and highly aggressive malignancy arising from the striated skeletal muscle fibre. It is commonly a childhood tumour and rarely seen in adults. The most predominant part commonly involved is head and neck. We are reporting a rare case of a 54 year old adult male with Rhabdomyosarcoma of nasopharynx with a non specific presentation of weight loss for past four months, fever, a perianal abscess and backache since 10 days. The haematological and biochemical parameters were within normal limits however C reactive protein and erythrocyte sedimentation rate were raised. An MRI for the pelvis, which was done for the extension of perianal abscess, also displayed some heterogeneous marrow signal, which raised the suspicion of some infiltrative process. Later, a bone scan, PET scan, and a biopsy of the nasopharaynx was done. The biopsy confirmed the findings of Rhabdomyosarcoma by showing marked pleomorphism with strong positive desmin and myogin stain. The patient was then referred to the oncology department for further management.

Effect of drinking high fluoride water on liver enzymes a comparitive cross-sectional study.

Objective: The aim of this study is to determine the effects of drinking water with high fluoride level on liver functions. Method: This is a descriptive comparative cross-sectional study conducted at Sammu rind village where the drinking water has increase fluoride content. The comparative area was Gadap town where the drinking water has normal fluoride level. Sampling was done randomly and sample size was calculated by WHO calculator and found to be 121 each for exposed and unexposed population. Blood samples taken for liver functions included bilirubin, AST, ALT, Alkaline phosphate, Gamma GT, total protein, albumin and globulin. SPSS version 16 was used for analysis. Mean and SD calculated for quantitative variable and the two comparative groups were cross-tabulated. To check the statistical significance t-test was applied. Results: There was no statistically significant difference with consideration to serum bilirubin, ALT, and AST. However, statistically significant difference was established with respect to alkaline phosphatase, Gamma GT total proteins and A/G ratio between two groups. Conclusion: In our study, there was no evidence of impaired liver function tests in subjects drinking water with high fluoride content.

A study on enhancing the quantum yield and antimicrobial activity of Pr(iii) by varying the coordination environment.

Praseodymium forms complexes easily with nitrogen and oxygen donor pyrazolines and also forms mixed ligand complexes with these pyrazolines and sulfur donor thio ligands such as dithiocarbamates and xanthates. These newly synthesized complexes have been characterized using elemental analysis, FTIR, TGA, SEM, TEM, PXRD and UV-visible spectral measurements. The isotopic studies were performed using DART mass spectrometry. The luminescent properties of these types of complexes were studied using a fluorescence spectrophotometer. The antimicrobial behavior of these praseodymium complexes was studied thoroughly during the present research.

Efficacy of dietetics in low resource communities: dietary intake and BMI of type 2 diabetics living in Karachi before and after receiving dietician's guidance.

This study was planned to assess the dietary intake of diabetic subjects and kind of dietary modification they have made after individualised dietary guidance. Information on clinical and dietary profile of 200 subjects was recorded at first visit of BIDE. Dietary guidance was given by dietician. Second visit was done after 3 months. Subjects having adequate intake of fruit and vegetable, milk and meat was 68, 38 and 63% for males and 52, 40 and 35% for females, respectively. Only 20.4% males and 5.9% females had usual adequate consumption of the four food groups. Overall adequacy of diet improved for 11.1% of males and 27% of females. Weight reduction was observed in 54.8% of females and 32.2% of males. Rate of BMI reduction was significantly higher in the group who had reduced their caloric intake. This first of its kind study from Pakistan, has documented the efficacy of dietary guidance and highlighted the need for further attention to assure balanced intake of foods form various food groups.

Mediation as a method of parent intervention in children's disputes.

This study examined the feasibility and short-term effects of mothers' use of mediation to help children (5 to 8 years) resolve disputes. Families in which mothers were trained to use mediation were compared with control families on intervention strategies at home and discussion of a recurring conflict in the laboratory. With training, mothers could use mediation strategies, and these strategies were favored by both mothers and children. Children responded appropriately to mediation (reasoning, discussing emotions, and understanding motivations more often than in control families). Mediation empowered children, particularly younger siblings, to solve conflict issues. Although questions of the long-term implications of mediation remain, this study suggests that mediation may be a powerful parenting tool, promoting social understanding and productive conflict resolution.