Multi-detector computed tomography angiographic evaluation of right ventricular outflow tract obstruction and other associated cardiovascular anomalies in tetralogy of Fallot patients.

PURPOSE: To evaluate various types of right ventricular outflow tract obstruction associated with tetralogy of Fallot (TOF) with emphasis on the abnormality of pulmonary arterial system and other associated cardiovascular anomalies using computed tomography (CT) angiography. MATERIAL AND METHODS: We retrospectively evaluated 184 consecutive previously diagnosed TOF patients who underwent CT angiography in our department. RESULTS: Infundibular with pulmonary valvular stenosis was the most common type of stenosis (47.28%) found, followed by isolated infundibular stenosis (34.23%). Isolated abnormality of both right and left pulmonary arteries was also noted. Right side aortic arch (23.91%) was the most common associated abnormality followed by double superior vena cava (9.78%). CONCLUSIONS: TOF is associated with various types of right ventricular outflow tract obstruction ranging from infundibular narrowing to isolated narrowing of right or left pulmonary arteries and is also associated with various other congenital abnormalities of the cardiovascular system. CT angiography is an excellent imaging modality, which provides comprehensive analysis of various abnormalities associated with TOF.

Contamination, a Major Problem in Nuclear Medicine Imaging: How to Investigate, Handle, and Avoid It.

We present a case study in which artifacts from collimator contamination and patient motion were seen on a bone scan. Any identified artifact must be further investigated and documented so as to detect its source and thus prevent its future occurrence.

Hypothyroidism in McCune-Albright Syndrome and Role of Bone Scan in Management of Fibrous Dysplasia: An Unusual Case Scenario with Review of Literature.

The McCune-Albright syndrome (MAS) is a triad of café-au-lait skin pigmentation, precocious puberty (PP), and polyostotic fibrous dysplasia of bone (FD). In general, FD seems to be the most common component of MAS but very rarely precocious puberty can be found in association with café-au-lait skin pigmentation in the absence of FD (about 1% of the cases). Therefore, a more clinically relevant definition of MAS is fibrous dysplasia of bone (FD) and at least one of the typical hyperfunctioning endocrinopathy and/or café-au-lait spots, with almost any combination possible. Bone scan can be the modality of choice to look for bone disease burden of fibrous dysplasia in most patients of MAS and may change the management accordingly. Most of the cases of MAS reported worldwide are associated with hyperthyroidism, up to best of our knowledge on the basis of literature search in pubmed and Google; no case was reported with hypothyroidism. Herein, we report a 12-year-old girl diagnosed with MAS and associated hypothyroidism. We have also reviewed the MAS related literature.