Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 20 de 44
Filter
2.
Rev Esp Patol ; 57(2): 128-132, 2024.
Article in English | MEDLINE | ID: mdl-38599733

ABSTRACT

Primary hepatic liposarcoma is an extremely rare malignant tumour derived from adipocytes and is part of the group of mesenchymal tumours. We present the case of a 43-year-old Hispanic male patient with a pleomorphic hepatic liposarcoma and absence of MDM2 gene amplification. Two years and six months after surgery, the patient is asymptomatic. The present case is the first report of this entity with positive immunohistochemical testing for p16, p53, S100, vimentin and absence of MDM2 gene amplification.


Subject(s)
Liposarcoma , Proto-Oncogene Proteins c-mdm2 , Humans , Male , Adult , Proto-Oncogene Proteins c-mdm2/genetics , Liposarcoma/pathology , Adipocytes/pathology
3.
Clin Transl Oncol ; 26(4): 825-835, 2024 Apr.
Article in English | MEDLINE | ID: mdl-37787973

ABSTRACT

Watch-and-wait has emerged as a new strategy for the management of rectal cancer when a complete clinical response is achieved after neoadjuvant therapy. In an attempt to standardize this new clinical approach, initiated by the Spanish Cooperative Group for the Treatment of Digestive Tumors (TTD), and with the participation of the Spanish Association of Coloproctology (AECP), the Spanish Society of Pathology (SEAP), the Spanish Society of Gastrointestinal Endoscopy (SEED), the Spanish Society of Radiation Oncology (SEOR), and the Spanish Society of Medical Radiology (SERAM), we present herein a consensus on a watch-and-wait approach for the management of rectal cancer. We have focused on patient selection, the treatment schemes evaluated, the optimal timing for evaluating the clinical complete response, the oncologic outcomes after the implementation of this strategy, and a protocol for surveillance of these patients.


Subject(s)
Rectal Neoplasms , Watchful Waiting , Humans , Consensus , Neoplasm Recurrence, Local/drug therapy , Rectal Neoplasms/pathology , Neoadjuvant Therapy/methods , Chemoradiotherapy/methods , Pathologic Complete Response , Treatment Outcome
5.
Healthcare (Basel) ; 11(5)2023 Feb 21.
Article in English | MEDLINE | ID: mdl-36900640

ABSTRACT

Due to the Coronavirus-19 (COVID-19) pandemic, most resources of the public health system were allocated to the increasing demand from respiratory patients. From this, it is expected that specialty consultations would decrease drastically. Access to dermatology care in the Chilean public health has been historically limited. To evaluate the impact of the pandemic on dermatology care, the total number of dermatological consultations (DCs) to the Chilean public sector in 2020 is analyzed according to sex and age range and compared with the available databases from 2017 to 2019. From this, 120,095 DCs were performed during 2020, with an incidence of 6.3 consultations per 1000 inhabitants. When compared to 2019 (n = 250,649), there was a 52.1% decrease. The regions most affected were located in the central part of Chile, which correlates with the regions most affected by the pandemic. Age and sex distributions remained similar to previous years but lower in amplitude. The month with the lowest number of consultations was April, with a gradual increase observed thereafter until December 2020. Although DCs decreased drastically in the Chilean public sector during 2020, sex and age range proportions were conserved, thus affecting all groups in a similar manner.

6.
Ann Coloproctol ; 2023 Jan 12.
Article in English | MEDLINE | ID: mdl-36632693

ABSTRACT

Granular cell tumors are predominantly benign soft tissue tumors originating from Schwann cells, whereas melanocytic nevi are benign proliferations of melanocytes. We present the case of a patient with the presence of both entities located in the cecum and anal canal, respectively, constituting an extremely rare coincidental finding. A 43-year-old woman was evaluated by colonoscopy for iron-deficiency microcytic anemia that had lasted for 1 year. Colonoscopy demonstrated a macular lesion of 0.3 cm with a melanocytic appearance in the anal canal; at the cecum level, a subepithelial, yellowish, and partially mobile firm nodular lesion measuring 1.3 cm was observed. A histopathological study showed a melanocytic nevus in the anal canal and a granular cell tumor in the cecum. This is the first reported case of a patient with the extremely rare coincidental-incidental finding of these 2 entities at the same time.

7.
Rev Electron ; 38(9)sept. 2013. ilus, graf
Article in Spanish | CUMED | ID: cum-55355

ABSTRACT

Se realizó una investigación documental sobre el tema de la clasificación de las investigaciones en salud, mediante un muestreo estratificado por tipos de investigaciones. Se analizaron 35 artículos que cumplieron el criterio de autoría reconocida en el tema, publicación en editoriales de impacto y alto nivel de actualidad, tanto nacional, como internacional. Las posibles causas de incoherencias y ambigüedades en las clasificaciones fueron indagadas por el estudio histórico-lógico, en cuya solución se elaboró una propuesta de escala para medir la evidencia científica de las investigaciones según su clasificación, que deviene en una clasificación mutuamente excluyente y exhaustiva (AU)


A documentary investigation about health research classification by means of a stratified sample by types of research was carried out with 35 articles fulfilling the criterion for authorship recognized in the field: publishing in high impact and current editorials, not only nationally, but also internationally. The possible causes of inconsistencies and ambiguities were investigated by the historic-logical study. To solve this situation a proposal to evaluate the scientific evidence of the health research according to its classification. This classification is mutually exclusive and exhaustive (AU)


Subject(s)
Research
8.
Rev. cuba. endocrinol ; 24(2)mayo-ago. 2013.
Article in Spanish | CUMED | ID: cum-53939

ABSTRACT

Introducción: las complicaciones cardiovasculares en los pacientes con diabetes mellitus tipo 1 pueden iniciarse desde edades tempranas. Objetivo: identificar las alteraciones de función ventricular en niños y adolescentes con diabetes mellitus 1. Métodos: se realizó un estudio de corte transversal en 52 niños y adolescentes (28 pacientes del sexo masculino y 24 del sexo femenino) con diagnóstico de diabetes mellitus tipo 1, con edades entre 2 y 18 años, así como 44 sujetos no diabéticos (22 pacientes del sexo masculino y 22 del sexo femenino), con edad similar al grupo de estudio, atendidos en el Servicio de Endocrinología del Hospital Pediátrico Docente William Soler, entre febrero de 2010 y agosto de 2011. A todos los pacientes se les realizó estudio ecocardiográfico utilizando un equipo Aloka 5500 y transductores de 3,5 y 5 MHz. Resultados: se encontraron diferencias significativas en la función diastólica de ambos ventrículos, así como en la función sistólica del ventrículo derecho en los pacientes con diabetes mellitus tipo 1 con respecto a los controles, y también una relación inversamente significativa con la variable de función diastólica del ventrículo derecho, el tiempo de evolución y la edad del diagnóstico de la diabetes mellitus tipo 1. Conclusiones: las alteraciones de la función diastólica y sistólica compatibles con miocardiopatía diabética se hallan presentes en niños y adolescentes con diabetes mellitus tipo 1, significativamente con mayor frecuencia que en los controles, lo que pudiera estar relacionado por el incremento de las hormonas durante la pubertad y la asociación con neuropatía autonómica cardiovascular(AU)


Introduction: cardiovascular complications can emerge at early ages in patients with type 1 diabetes mellitus. Objective: to identify alterations in ventricle function of children and adolescents with type 1 diabetes mellitus. Methods: a cross-sectional study was conducted in 52 children and adolescents (28 males and 24 females) diagnosed with type 1 diabetes mellitus, aged 2 to 8 years and in 44 non-diabetic subjects (22 males and 22 females) with ages similar to those of the study group. They had been all seen at the endocrinology service of William Soler pediatric teaching hospital February 2010 to August 2011 and they were all performed echocardiographic exams using Aloka 5500 equipment and 3,5 and 5 MHz transducers. Results: there were significant differences in the diastolic function of both ventricles as well as in the systolic function of the right ventricle of patients with type 1 diabetes mellitus in comparison with the controls. Likewise, there was a reversely significant relation with the diastolic function variable of the right ventricle, the length of progression and the ages at diagnosis of type 1 diabetes mellitus. Conclusions: the alterations in the diastolic and systolic functions compatible with diabetic myocardiopathy are present in children and adolescents with type 1 diabetes mellitus more frequently than in the control group, all of which could be related to the increase in the number of hormones in puberty and the association with autosomal cardiovascular neuropathy(AU)


Subject(s)
Humans , Child , ADOLENCESTE , Child, Preschool , Male , Female , Diabetes Mellitus, Type 1/complications , Diabetic Cardiomyopathies/etiology , /diagnosis , Echocardiography/methods , Cross-Sectional Studies
9.
Rev Electron ; 38(8)ago. 2013.
Article in Spanish | CUMED | ID: cum-55349

ABSTRACT

Se realizó una investigación documental sobre el tema de la clasificación de las investigaciones en salud, mediante un muestreo estratificado por tipos de investigaciones, se analizaron 35 artículos que cumplieron el criterio de autoría reconocida en el tema, publicación en editoriales de impacto y alto nivel de actualidad, tanto nacional como internacional. Las posibles causas de incoherencias y ambigüedades en las clasificaciones fueron indagadas por el estudio histórico-lógico. Se concluyó que es posible elaborar un modelo de clasificación de investigaciones en salud simple, pero con rigor científico, que permita su gradual introducción en el postgrado académico (AU)


A documentary investigation about health research classification by means of a stratified sample by types of research was carried out with 35 articles fulfilling the criterion for authorship recognized in the field: publishing in high impact and current editorials, not only nationally, but also internationally. The possible causes of inconsistencies and ambiguities were investigated by the historic-logical study. It concludes that it is possible to develop a classification model of simple health research, scientifically rigorous to permit its gradual introduction into the postgraduate academic course (AU)


Subject(s)
Research/classification
10.
Rev. cuba. endocrinol ; 24(2): 176-187, mayo-ago. 2013.
Article in Spanish | LILACS, CUMED | ID: lil-679982

ABSTRACT

Introducción: las complicaciones cardiovasculares en los pacientes con diabetes mellitus tipo 1 pueden iniciarse desde edades tempranas. Objetivo: identificar las alteraciones de función ventricular en niños y adolescentes con diabetes mellitus 1. Métodos: se realizó un estudio de corte transversal en 52 niños y adolescentes (28 pacientes del sexo masculino y 24 del sexo femenino) con diagnóstico de diabetes mellitus tipo 1, con edades entre 2 y 18 años, así como 44 sujetos no diabéticos (22 pacientes del sexo masculino y 22 del sexo femenino), con edad similar al grupo de estudio, atendidos en el Servicio de Endocrinología del Hospital Pediátrico Docente William Soler, entre febrero de 2010 y agosto de 2011. A todos los pacientes se les realizó estudio ecocardiográfico utilizando un equipo Aloka 5500 y transductores de 3,5 y 5 MHz. Resultados: se encontraron diferencias significativas en la función diastólica de ambos ventrículos, así como en la función sistólica del ventrículo derecho en los pacientes con diabetes mellitus tipo 1 con respecto a los controles, y también una relación inversamente significativa con la variable de función diastólica del ventrículo derecho, el tiempo de evolución y la edad del diagnóstico de la diabetes mellitus tipo 1. Conclusiones: las alteraciones de la función diastólica y sistólica compatibles con miocardiopatía diabética se hallan presentes en niños y adolescentes con diabetes mellitus tipo 1, significativamente con mayor frecuencia que en los controles, lo que pudiera estar relacionado por el incremento de las hormonas durante la pubertad y la asociación con neuropatía autonómica cardiovascular(AU)


Introduction: cardiovascular complications can emerge at early ages in patients with type 1 diabetes mellitus. Objective: to identify alterations in ventricle function of children and adolescents with type 1 diabetes mellitus. Methods: a cross-sectional study was conducted in 52 children and adolescents (28 males and 24 females) diagnosed with type 1 diabetes mellitus, aged 2 to 8 years and in 44 non-diabetic subjects (22 males and 22 females) with ages similar to those of the study group. They had been all seen at the endocrinology service of William Soler pediatric teaching hospital February 2010 to August 2011 and they were all performed echocardiographic exams using Aloka 5500 equipment and 3,5 and 5 MHz transducers. Results: there were significant differences in the diastolic function of both ventricles as well as in the systolic function of the right ventricle of patients with type 1 diabetes mellitus in comparison with the controls. Likewise, there was a reversely significant relation with the diastolic function variable of the right ventricle, the length of progression and the ages at diagnosis of type 1 diabetes mellitus. Conclusions: the alterations in the diastolic and systolic functions compatible with diabetic myocardiopathy are present in children and adolescents with type 1 diabetes mellitus more frequently than in the control group, all of which could be related to the increase in the number of hormones in puberty and the association with autosomal cardiovascular neuropathy(AU)


Subject(s)
Humans , Male , Female , Child, Preschool , Child , Adolescent , Diabetes Mellitus, Type 1/diagnosis , Diabetic Cardiomyopathies/diagnosis , Diabetic Cardiomyopathies/etiology , Echocardiography/methods , Cardiovascular Diseases/complications , Cross-Sectional Studies
11.
Rev Electron ; 36(4)oct.-dic. 2011.
Article in Spanish | CUMED | ID: cum-47782

ABSTRACT

Se realiza un análisis crítico de la literatura de Metodología de la Investigación en Salud mas actualizada a la que se puede acceder en nuestra provincia, en busca de elementos metodológicos que expliquen las insuficiencias de nuestros investigadores en el planteamiento de problemas científicos y la coherencia de sus investigaciones. Se demuestra la necesidad de definir los conceptos: problema profesional e investigación profesional, los que permiten la elaboración consciente del planteamiento de problemas científicos y el uso adecuado del método científico, como la manera más eficiente de realizar una investigación científica, evitando la rutina de las investigaciones profesionales(AU)


A critical analysis about the most updated bibliography related to Health Research Methodology in our province was carried out in search of the methodological elements that might clarify the inadequacies of researchers when stating the scientific problems and coherence of their researches. The investigation shows the need of defining concepts like professional problem and professional research, both of which allow the conscious elaboration of the analysis of scientific problems and the adequate use of the scientific method as the most efficient way to conduct a scientific research avoiding the routine of professional researches (AU)


Subject(s)
Scientific Research and Technological Development , Methods
12.
Rev Electron ; 36(4)oct.-dic. 2011.
Article in Spanish | CUMED | ID: cum-47781

ABSTRACT

Se realizó una investigación documental sobre las categorías hipótesis y objetivos en temas relacionados con la metodología de la investigación, buscando en las mismas las coincidencias y divergencias respecto a su definición, requisitos, funciones, importancia y alcance en la investigación científica, con la finalidad de precisar con la mayor claridad posible y el adecuado rigor científico, el lugar de ambas categorías en el glosario de términos de la ciencia. Se concluye que a ambas categorías se le atribuyen similares requisitos, funciones e importancia para la investigación científica, y sólo se diferencian en la forma de redacción, en la estructura y en el papel interpretativo en las ciencias: las hipótesis los tienen definidos y los objetivos no. En este sentido se valora el alcance limitado del objetivo, al privar al investigador de la creatividad característica del proceso de investigación científica ante la disyuntiva de no poderlos alcanzar (AU)


A documentary research on the categories of hypothesis and objectives on issues related to research methodology was conducted, looking for their coincidences and differences according to their definition, requirements, functions, importance and scope in the scientific research in order to specify as clearly as possible and with the appropriate scientific rigor, the place of both categories in the glossary of scientific terms. As a conclusion the investigation states that both categories are assigned similar requirements, functions and importance for the scientific research, and they only differ in the form of writing, the structure and their interpretative role in science, all of which are defined in the hypothesis and not in the objectives. In this sense, the limited scope of aims is taken into account to deprive the researcher of the creative characteristic of the process of scientific research considering the dilemma of not meeting them (AU)


Subject(s)
Humans , Hypothesis-Testing , Organizational Objectives , Materia Medica Study Methods
13.
Cir Cir ; 79(6): 564-9, 2011.
Article in English, Spanish | MEDLINE | ID: mdl-22169377

ABSTRACT

BACKGROUND: Leiomyoma is the most common benign esophageal tumor that originates in the muscular layer, with the most common site located in the distal third of the esophagus. Its growth causes symptoms due to partial obstruction of the esophageal lumen, leading to the diagnosis and subsequent treatment. Today, due to modern minimally invasive surgical techniques, complete removal of these tumors can be accomplished with minimal morbidity and excellent results. CASE REPORT: We report the case of a 49-year-old female with a history of dysphagia, epigastric pain, and halitosis. She was diagnosed with a benign tumor originating from the muscular layer of the distal esophagus. Multiple biopsies had previously been taken, without histological confirmation. The patient underwent surgery where complete tumor enucleation was done laparoscopically. CONCLUSIONS: Preoperative diagnosis of these tumors should be based on clinical history and studies such as esophagoscopy and endoscopic ultrasound. Laparoscopic enucleation is the treatment of choice for leiomyomas of the esophagogastric junction. Biopsy specimens should be avoided because histology is not always possible. Furthermore, they are related to rupture of the esophageal mucosa during surgical treatment. After enucleation in selected patients, anti-reflux procedure should be carried out in order to protect the area of surgical resection and prevent complications from weakening the lower esophageal sphincter, as well as to resolve reflux symptoms.


Subject(s)
Esophageal Neoplasms/surgery , Laparoscopy/methods , Leiomyoma/surgery , Deglutition Disorders/etiology , Endosonography , Esophageal Neoplasms/complications , Esophageal Neoplasms/diagnostic imaging , Esophageal Neoplasms/pathology , Esophagoscopy , Female , Gastroesophageal Reflux/etiology , Halitosis/etiology , Hernia, Hiatal/complications , Humans , Leiomyoma/complications , Leiomyoma/diagnostic imaging , Leiomyoma/pathology , Middle Aged , Tomography, X-Ray Computed
14.
Clin Transl Oncol ; 13(1): 50-6, 2011 Jan.
Article in English | MEDLINE | ID: mdl-21239355

ABSTRACT

INTRODUCTION: The EORTC Quality of Life (QL) Group has developed a questionnaire -the EORTC QLQ-CR29- for evaluating QL in colorectal cancer. The aim of this study is to assess the psychometric properties of the EORTC QLQCR29 when applied to a sample of Spanish patients. MATERIALS AND METHODS: Eighty-four locally advanced rectal cancer patients in the treatment follow-up period after receiving surgery and neoadjuvant chemoradiotherapy were included in the study. Seventy subjects also had adjuvant chemotherapy. Patients completed both the EORTC QLQC30 and the QLQ-CR29 once. The psychometric evaluation of the questionnaire's structure, reliability, and convergent, divergent and known-groups validity was performed. RESULTS: Multitrait scaling analysis showed that three of the multi-item scales met the standards of convergent and discriminant validity. These same scales reached the 0.7 Cronbach's coefficient criterion or were close to it. In both analyses exceptions were observed in the blood and mucus in stool scale. Correlations between the scales of the QLQC30 and the module were low (r<0.02) in most cases. A few areas with more related content had higher correlations (r<0.05). Group comparison analyses showed differences in QL between groups of patients based on age, comorbidity, performance status, receipt of adjuvant chemotherapy and surgery modality. CONCLUSIONS: The EORTC QLQ-CR29 is a reliable and valid instrument when applied to a sample of Spanish rectal cancer patients. These results are in line with those of the EORTC validation study.


Subject(s)
Carcinoma/psychology , Carcinoma/therapy , Colorectal Neoplasms/psychology , Colorectal Neoplasms/therapy , Quality of Life , Surveys and Questionnaires , Adult , Aged , Aged, 80 and over , Carcinoma/rehabilitation , Colorectal Neoplasms/rehabilitation , Combined Modality Therapy , Europe , Female , Humans , Male , Medical Oncology/organization & administration , Middle Aged , Reproducibility of Results , Social Class , Societies, Medical/organization & administration , Spain
15.
Rev Electron ; 35(4)abr.-jun. 2010.
Article in Spanish | CUMED | ID: cum-45783

ABSTRACT

Se realizó una investigación exploratoria, empírica y teórica sobre la situación social que acarrea a las investigaciones médicas en la provincia de Las Tunas, con el objetivo de determinar la forma más eficaz de impulsar el desarrollo de las mismas, tomándose como unidad de observación para la parte empírica los informes de investigación presentados a diferentes niveles, de los cuales se recogen aspectos relacionados con sus autores, sus producciones científicas, el modo y estilo de vida en relación con la actividad científica. Todo lo cual es minuciosamente analizado bajo las concepciones histórico filosóficas del desarrollo del conocimiento científico de la humanidad, mediante consulta de fuentes documentales sobre el tema en cuestión, permitiendo identificar las siguientes características en el contexto estudiado: 1) el personal profesional de la salud en la provincia experimenta enajenación por la ciencia; 2) las Ciencias Médicas en la provincia están en el nivel de ciencia amateur; 3) una arista muy sensible de la problemática descrita, es la moral que sirve de base para la concepción de un modelo teórico para dar solución a la misma. Se propone, como instrumentación del modelo concebido, la aplicación de una estrategia de intervención comunitaria, a través de una investigación acción en la comunidad médica de la provincia Las Tunas (AU)


An exploratory empiric and theoretical research was carried out about the social situations of the medical research in Las Tunas, with the objective to determine the most effective form to develop this investigations; taking as observation unit for the empiric part the investigation reports presented at different levels, of which aspects related with their authors were selected, their scientific productions, the way and lifestyle in connection with the scientific activity; were analyzed in detail under the philosophical historical conceptions of the development of the humanity's scientific knowledge, by means of consultation of documental sources on the topic in question, allowing for the identification of the following characteristics in the context studied: 1) the professional personnel of public health in the county experiences alienation for science. 2) the Medical Sciences in the province are in the level of amateur science. 3) a very sensitive edge of the problem described is the moral that serves as base for the conception of a theoretical model to give its solution. It is proposed as instrumentation of the pattern designed , the application of a strategy of community intervention through action research in the medical community of Las Tunas province(AU)


Subject(s)
Humans , Science , Qualitative Research , Social Problems
16.
Cir Cir ; 78(6): 522-7, 2010.
Article in English, Spanish | MEDLINE | ID: mdl-21214989

ABSTRACT

BACKGROUND: Identifying the level of culture and awareness on patient safety is essential in order to improve the quality of care. The objective of our research was to assess patient safety culture in healthcare professionals. METHODS: Derived from the implementation of a survey on patient safety to 174 health professionals, data related to demographic characteristics were analyzed. Scores were determined on the 12 dimensions of the scale including additional items on perception and degree of overall patient safety, frequency and number of events reported, as well as Cronbach's alpha for the different dimensions. Descriptive statistics were used. RESULTS: Overall perception on safety was 51%. The lowest dimension was communication openness (38%), whereas organizational learning had the highest scores (68%). Analysis showed low Cronbach's alpha for dimensions of overall perception on safety (0.35), non-punitive response to error (0.55) and staff allocation (0.12). CONCLUSIONS: A low overall perception on patient safety indicates the need for increased institutional actions for improvement. Low Cronbach's alpha in some measurements may suggest the need for adjustments to the instrument. Results on the overall perception on patient safety, nonpunitive response to error and staff allocation (staffing) should be interpreted with caution, given the low reliability of such dimensions.


Subject(s)
Attitude of Health Personnel , Safety Management , Cross-Sectional Studies , Culture , Humans
17.
Salud Publica Mex ; 51(5): 361-71, 2009.
Article in Spanish | MEDLINE | ID: mdl-19936549

ABSTRACT

OBJECTIVE: To carry out the epidemiological analysis of 122 influenza A (H1N1) deaths confirmed by laboratory and help to improve the diagnosis and timely managing of cases. MATERIAL AND METHODS: A total of 122 clinical records were analyzed of patients with confirmed influenza A (H1N1) virus infection who died. RESULTS: Fifty-one percent of patients were female and 49% were male. A total of 45.l% who died were between 20 and 39 years old. Overall fatality was 2.2% and ranged between 0.3% for the l0 to l9 year-old group to 6.3% for the 50 to 59 year-old group. Forty-three percent of deaths were concentrated in only two of the thirty-two states and 5l% received medical attention in social security institutions. Only l7% received hospital attention within 72 hours and 42% died within 72 hours of hospital attention. DISCUSSION: Novel Influenza A (H1N1) virus produces higher mortality in young people whereas seasonal influenza has a greater impact on young children and older people. Delay in medical care and the associated morbidity were relevant factors for death.


Subject(s)
Influenza A Virus, H1N1 Subtype , Influenza, Human/mortality , Adolescent , Adult , Child , Child, Preschool , Female , Humans , Infant , Influenza, Human/epidemiology , Male , Mexico/epidemiology , Middle Aged , Young Adult
18.
Salud pública Méx ; 51(5): 361-371, Sept.-Oct. 2009. graf, tab
Article in Spanish | LILACS | ID: lil-531226

ABSTRACT

OBJETIVO: Efectuar el análisis epidemiológico de 122 defunciones por influenza A (H1N1) confirmadas por laboratorio y contribuir a mejorar el diagnóstico y atención oportuna de casos. MATERIAL Y MÉTODOS: Se Analizaron 122 expedientes de pacientes fallecidos por influenza A (H1N1). RESULTADOS: Una proporción de 51 por ciento correspondió a mujeres y 49 por ciento a varones. Hasta 45.1 por ciento ocurrió entre los 20 y 39 años. La letalidad general fue de 2.2 por ciento y varió entre 0.3 por ciento en el grupo de 10 a 19 años y 6.3 por ciento en el de 50 a 59. Una cifra de 43 por ciento de las defunciones se concentró en dos de las 32 entidades federativas y 5l por ciento se atendió en instituciones de seguridad social. Sólo 17 por ciento recibió atención hospitalaria en las primeras 72 horas y 42 por ciento falleció en las primeras 72 horas de hospitalización. En 58.2 por ciento de los fallecidos había algún padecimiento asociado. DISCUSIÓN: El Nuevo virus A (H1N1) produce mayor mortalidad en personas jóvenes, al contrario de lo que sucede con la influenza estacional que muestra un mayor impacto en niños pequeños y personas de edad avanzada. El retraso de la atención médica y la morbilidad asociada fueron factores relevantes del fallecimiento.


OBJECTIVE: To carry out the epidemiological analysis of 122 influenza A (H1N1) deaths confirmed by laboratory and help to improve the diagnosis and timely managing of cases. MATERIAL AND METHODS: A total of 122 clinical records were analyzed of patients with confirmed influenza A (H1N1) virus infection who died. RESULTS: Fifty-one percent of patients were female and 49 percent were male. A total of 45.l percent who died were between 20 and 39 years old. Overall fatality was 2.2 percent and ranged between 0.3 percent for the l0 to l9 year-old group to 6.3 percent for the 50 to 59 year-old group. Forty-three percent of deaths were concentrated in only two of the thirty-two states and 5l percent received medical attention in social security institutions. Only l7 percent received hospital attention within 72 hours and 42 percent died within 72 hours of hospital attention. DISCUSSION: Novel Influenza A (H1N1) virus produces higher mortality in young people whereas seasonal influenza has a greater impact on young children and older people. Delay in medical care and the associated morbidity were relevant factors for death.


Subject(s)
Adolescent , Adult , Child , Child, Preschool , Female , Humans , Infant , Male , Middle Aged , Young Adult , Influenza A Virus, H1N1 Subtype , Influenza, Human/mortality , Influenza, Human/epidemiology , Mexico/epidemiology , Young Adult
19.
Rev. cuba. pediatr ; 80(1)ene.-mar. 2008. graf
Article in Spanish | CUMED | ID: cum-36530

ABSTRACT

Reportamos la evolución de un paciente que podía ser operado mediante el procedimiento Norwood I, pero a quien se realizó un procedimiento paliativo híbrido alternativo. Se trató de un recién nacido de 13 días de edad, que ingresó en nuestro centro con insuficiencia cardíaca congestiva. Se le realizó ecocardiograma, en el que se confirmó atresia aórtica, coartación aórtica y comunicación interventricular. Se le aplicó un procedimiento consistente en atrioseptostomía con balón (Rashkind), cerclaje de las ramas pulmonares y colocación de una endoprótesis vascular ('stent') en el conducto arterioso. El paciente presentó una evolución estable durante la operación. Evaluamos su comportamiento hemodinámico durante las primeras 72 h(AU)


The evolution of a patient that could be operated on by the Norwood I procedure, but underwent an alternative hybrid palliative procedure instead, was reported. The patient, a 13-day-old newborn infant was admitted in our centre with congestive heart failure. An echocardiogram was performed, and aortic atresia, aortic coarctation and intraventricular communication were confirmed. A procedure consisting in balloon atrioseptostomy (Rashkind), cerclage of the pulmonary branches and placement of a vascular endoprosthesis (stent) in the arterious duct was applied. The patient presented a stable evolution during the operation. His hemodynamic behaviour was evaluated during the first 72 hours(AU)


Subject(s)
Humans , Infant, Newborn , Central Venous Pressure/physiology , Cardiovascular Physiological Phenomena , Environmental Monitoring
20.
Mediciego ; 14(supl.1)mar. 2008. ilus
Article in Spanish | CUMED | ID: cum-39464

ABSTRACT

Se presenta el caso de una niña de 13 meses de edad que presenta episodio de insuficiencia cardíaca severa, se diagnostica miocarditis fulminante, y se evoluciona hasta la curación. Se describe el manejo de paciente y se hace un breve comentario del tema (AU)


It is presented a case of a 13 months girl that presents an episode of severe heart insufficiency, it is diagnosed crushing myocarditis and it is evolved until the recovery. It is described the management of the patient and it is done a brief comment on the topic (AU)


Subject(s)
Humans , Female , Infant , Myocarditis/diagnosis , Heart Failure , Case Reports
SELECTION OF CITATIONS
SEARCH DETAIL