ABSTRACT
Lyme neuroborreliosis (LNB) caused by the spirochete bacteria Borrelia burgdorferi sensu lato complex is the most common bacterial neuroinfection in Denmark (180 cases per year). One of the main challenges to LNB is the diagnosis due to its variant manifestations often involving the skin, musculosceletal or nervous system affecting patient morbidity. Recent data shows a diagnostic delay of 21 days in laboratory-confirmed patients in Denmark. The aim of this review is to summarise current state of knowledge concerning clinical manifestations, diagnostic assessment, antibiotic therapy, and prognosis.
Subject(s)
Borrelia burgdorferi , Lyme Neuroborreliosis , Adult , Anti-Bacterial Agents/therapeutic use , Delayed Diagnosis , Humans , Lyme Neuroborreliosis/diagnosis , Lyme Neuroborreliosis/drug therapyABSTRACT
We describe a case of severe community-acquired adenovirus pneumonia in an immunocompetent 66-year-old man. He presented with one-day history of malaise, fever and emesis. Initial laboratory tests showed increased C-reactive protein level, normal white blood cell count and mild anaemia. The chest X-ray was unremarkable. A few days following admission his condition deteriorated to respiratory failure and sepsis. Chest CT-images showed bilateral infiltrates and pleural effusion. Pleural fluid and tracheal aspirates were positive for adenovirus by polymerase chain reaction assay. No other microbial pathogens were identified.
