ABSTRACT
Fahr's disease is a rare clinical neurodegenerative entity, occurring mainly in 4th or 5th decade, showing gradually progressive bilateral symmetric calcifications in basal ganglia, subcortical white matter, thalami or cerebellum, which can lead to movement disorder and/or neuropsychiatric manifestations. We present two cases in the same family; a 68-year-old brother had involuntary jerky movements of hand and dysarthria for 10 years while the 44-year-old sister had right lower limb spasticity and decreased vision for 2 years. The serial MRI scans showed slow progression in the bilateral subcortical white matter and cerebellar dentate nuclei calcifications along with surrounding reactive gliosis.
Subject(s)
Basal Ganglia Diseases , Calcinosis , Neurodegenerative Diseases , Aged , Basal Ganglia Diseases/diagnostic imaging , Calcinosis/diagnosis , Calcinosis/diagnostic imaging , Humans , Magnetic Resonance Imaging , Male , Neurodegenerative Diseases/diagnosis , Neurodegenerative Diseases/diagnostic imagingABSTRACT
Circumportal annular pancreas (CAP) also known as portal annular pancreas (PAP) is an uncommon pancreatic anatomic variant in which normal pancreatic tissue completely surrounds the portal vein and can be mistaken for mass of pancreatic head. We present here a case of a 65 years old woman who was a diagnosed case of endometrial carcinoma, underwent CT scan for further metastatic workup which revealed this rare pancreatic variant.
Subject(s)
Pancreas/abnormalities , Pancreatic Diseases/diagnostic imaging , Aged , Female , Humans , Pancreas/diagnostic imaging , Tomography, X-Ray ComputedABSTRACT
Neurolymphomatosis (NL) is an uncommon clinical condition, characterised by lymphomatous infiltration of the central and/or peripheral nervous system. Most often it is caused by B-cell non-Hodgkin's lymphoma (NHL). Clinically, patients usually present with neuropathy involving the nerve roots, plexuses, peripheral or cranial nerves. NL usually occurs as a complication of prior lymphoma, but it can also present in the form of relapsed lymphoma. It is important to diagnose and start early treatment in all cases of nodal or visceral (including neural) lymphoma with chemo and/or radiation therapy. The PET-CT and MRI can help in making diagnosis. We are presenting a case of 28-year male patient, diagnosed as diffuse large B-cell lymphoma on the background of follicular lymphoma, which initially responded to treatment but then presented with NL, based on clinical history and radiological findings which were confirmed by histopathology.
