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Bioorg Med Chem Lett
; 16(24): 6328-33, 2006 Dec 15.
Article
in English
| MEDLINE
| ID: mdl-17005394
ABSTRACT
PPAR ligands with varied subtype selectivity have been synthesized using an achiral aminomethyl dihydrocinnamate template. Several compounds in this series have demonstrated potent plasma glucose and triglyceride lowering capability in rodent models of type 2 diabetes.