ABSTRACT
Currently, the number of contact lens users in the world is approximately 10% of the total population of developed countries. Despite the undeniable advantages of contact lenses over eyeglasses, complications are an unpleasant aspect of their use. An analysis of the literature showed that purulent-inflammatory complications have not been fully described. PURPOSE: To study the prevalence of keratitis associated with contact lenses, its clinical manifestations, microbial etiology, and sensitivity to antibiotics. MATERIAL AND METHODS: The study analyzes case histories of 171 patients with infectious keratitis treated at the Children's Republican Clinical Hospital of the Ministry of Health of the Republic of Tatarstan in 2016-2018. RESULTS: The retrospective analysis revealed an increase in both the number of infectious keratitis and the keratitis associated with contact correction. All patients had a severe course of keratitis with the formation of gross opacity. The leading pathogens were Pseudomonas aeruginosae and Klebsiella oxytoca. The pathogens were not 100% sensitive to any one of the 7 studied antibiotics. The smallest percentage of resistant strains (12.5%) was determined for fluoroquinolones of the 2nd and 3rd generation (ciprofloxacin and levofloxacin), as well as meropenem. CONCLUSION: Considering the number of contact lens users in the world, keratitis associated with contact lenses poses a serious problem.
Subject(s)
Contact Lenses , Eye Infections, Bacterial , Keratitis , Pseudomonas Infections , Adolescent , Anti-Bacterial Agents/therapeutic use , Child , Contact Lenses/adverse effects , Humans , Keratitis/diagnosis , Keratitis/epidemiology , Keratitis/etiology , Pseudomonas Infections/drug therapy , Retrospective StudiesABSTRACT
Currently, the number of keratomycoses and the interest of ophthalmologists to this type of keratitis have significantly increased due to the severity of the disease and non-satisfactory outcomes in some cases. According to published data, perforation of the cornea develops 6 times more often after keratomycosis than after keratitis of another etiology. The outcomes of keratoplasty in these patients are also not always satisfactory. The article presents a relatively rare clinical case of keratomycosis in a teenager caused by Arthrographis kalrae. The description of diseases caused by this microorganism is rarely found in literature. We have found only 4 cases describing keratomycosis caused by A. kalrae. The case presented here is associated with the use of contact lenses. The microorganism was identified from a container with contact lenses. Fungicidal drugs such as Anidulafungin, Voriconazole, as well as topical and systemical Amphotericin B were used in the treatment. The patient was discharged with a good functional result (best-corrected visual acuity of 0.7). This case indicates the possibility of a positive functional outcome in treating keratomycosis with present-day means.