Multicast communication technology is widely applied in wireless environments with a high device density. Traditional wireless network architectures have difficulty flexibly obtaining and maintaining global network state information and cannot quickly respond to network state changes, thus affecting the throughput, delay, and other QoS requirements of existing multicasting solutions. Therefore, this paper proposes a new multicast routing method based on multiagent deep reinforcement learning (MADRL-MR) in a software-defined wireless networking (SDWN) environment. First, SDWN technology is adopted to flexibly configure the network and obtain network state information in the form of traffic matrices representing global network links information, such as link bandwidth, delay, and packet loss rate. Second, the multicast routing problem is divided into multiple subproblems, which are solved through multiagent cooperation. To enable each agent to accurately understand the current network state and the status of multicast tree construction, the state space of each agent is designed based on the traffic and multicast tree status matrices, and the set of AP nodes in the network is used as the action space. A novel single-hop action strategy is designed, along with a reward function based on the four states that may occur during tree construction: progress, invalid, loop, and termination. Finally, a decentralized training approach is combined with transfer learning to enable each agent to quickly adapt to the dynamic changes of network link information and accelerate convergence. Simulation experiments show that MADRL-MR outperforms existing algorithms in terms of throughput, delay, packet loss rate, etc., and can establish more intelligent multicast routes. Code and model are available at https://github.com/GuetYe/MADRL-MR_code.
Although partially hydrogenated oil (PHO) provides foods with outstanding thick tastes and pronounced "creamy" flavor, the high level of artificial trans-fatty acids (TFA; about 30%) limits its usages around the world in the near future. It is necessary to produce trans-free alternatives with similar tastes to PHO. The relationship between sensory attributes and physicochemical characteristics of PHO and four typical specialty fats were therefore analyzed in the present study. PHO exhibited the highest greasiness score (8.19), accompanying by mild creaminess and aftertaste as well as a weak coolness during swallow, which were resulted from the close-packed arrangements of TFA, its cis-counterparts and other long chain fatty acids. None of artificial trans-fats, mainly anhydrous milk fat, cocoa butter, and coconut oil and its fully hydrogenated counterpart, were similar to PHO in terms of these sensory attributes. The unique fatty acid species of PHO and their arrangements contributed to the relatively smooth solid fat content profile and melting-crystallization curve, as well as forming uniform and dense ß' crystal-structures (Db=1.80). The Pearson correlation analyses relevelled that long chain fatty acids, e.g., t-C18:1 and C18:1, and melting final temperatures were generally positive correlated with greasiness, creaminess and aftertaste; whereas these indices were negatively correlated with coolness. The melting enthalpy was highly connected with coolness, which reflected the endothermic effectiveness during the melting process of fats in the mouth. These indices screened by correlation analyses that were strongly correlated with sensory attributes could provide references for producing trans-free alternatives.
Plant Oils , Trans Fatty Acids , Plant Oils/chemistry , Dietary Fats , Fatty Acids/analysis , Fats , Coconut Oil , Trans Fatty Acids/analysis
Idesia polycarpa pulp oil (IPPO) has the potential to become the new high-quality vegetable oil. The chemical parameters, fatty acid composition, bioactive ingredients, and antioxidant capacity of five Chinese regions of IPPO were studied comparatively, with significant differences among the regions. The oils were all abundant in unsaturated fatty acids, including linoleic acid (63.07 ± 0.03%-70.69 ± 0.02%), oleic acid (5.20 ± 0.01%-7.49 ± 0.03%), palmitoleic acid (4.31 ± 0.01%-8.19 ± 0.01%) and linolenic acid (0.84 ± 0.03%-1.34 ± 0.01%). IPPO is also rich in active substances such as tocopherols (595.05 ± 11.81-1490.20 ± 20.84 mg/kg), which are made up of α, ß, γ and δ isomers, ß-sitosterol (1539.83 ± 52.41-2498.17 ± 26.05 mg/kg) and polyphenols (106.77 ± 0.86-266.50 ± 2.04 mg GAE/kg oil). The free radical scavenging capacity of IPPO varies significantly depending on the region. This study may provide important guidance for the selection of Idesia polycarpa and offer insights into the industrial application of IPPO in China.
We aimed to observe changes in angle width and choroidal thickness (CT) before and after phacoemulsification intraocular lens implantation (PEI) combined with goniosynechialysis (GSL) in patients with primary angle-closure glaucoma (PACG) complicated by cataracts. This prospective cohort study included 60 patients with PACG complicated by cataracts from the Department of Ophthalmology of Shaoxing People's Hospital, China. Patients underwent PEI combined with GSL (PEI-GSL group) or laser peripheral iridotomy (LPI) followed by PEI (PEI group). Intraocular pressure (IOP) and endothelial counts were significantly decreased in both groups after surgery, while best-corrected visual acuity and central anterior chamber depth were significantly increased. However, there were no significant differences between the two groups. The opening degrees of room corners at 12, 3, 6, and 9 o'clock were recorded as AA12, AA3, AA6, and AA9, respectively. Anterior chamber depth was significantly increased postoperatively compared to preoperatively in both groups, with no significant between-group differences (all ps > 0.05). At 1, 3, and 6 months postoperatively, the width at AA12, AA3, and AA9 points was higher in the PEI-GSL group than in the PEI group (all ps < 0.05). Significant between-group differences at AA6 were observed preoperatively (p = 0.023) and at 1 (p = 0.027) and 3 (p = 0.033) months postoperatively but not at 6 months postoperatively (p = 0.055). CT was smaller postoperatively than preoperatively (all ps < 0.001). The present study suggests that patients with PACG who underwent PEI with or without GSL had reduced IOP and CT after surgery.
MOOCs have attracted millions of learners worldwide by providing the public with convenient access to learning and quality educational resources, but the high dropout rate in MOOCs is still an urgent problem. Drawing upon Situation-Organism-Behavior-Consequence framework and interpersonal attraction theory, this study investigates the relationship between instructor attractiveness and MOOC course completion and further analyzes the impact of MOOC course completion on their career development. The results reveal that knowledge attractiveness and communication attractiveness significantly influence learners' thirst for knowledge. Communication attractiveness and physical attractiveness significantly influence learners' parasocial relationships. The thirst for knowledge and parasocial relationships are important antecedents of course completion for in-service learners and in-service learners' completion of MOOC courses positively affects their workplace benefits. The findings provide new perspectives for the research domain of online education.
The removal of zearalenone (ZEN) from degummed corn oil (DCO) using hydrolase on a batch-refining unit was studied. According to single-factor and response surface experiments, the optimum technological conditions for reaching the maximum degradation rate were a temperature of 39.01 °C, a pH of 8.08, a time of 3.9 h, and an enzyme dosage of 44.7 mg/kg, whereby the rate of ZEN degradation can reach 94.66%. Different effects on the removal of ZEN were observed at different initial ZEN contents under the optimal technological conditions, of which the decrease was rapid for high ZEN content and slow for low ZEN content.
Aim: This study aimed to provide profiles of microorganisms isolated from bile and antibiotic susceptibility patterns of biliary tract infections (BTIs) in our center. Methods: A total of 277 patients diagnosed with BTIs at the Second Affiliated Hospital of Harbin Medical University from 2011 to 2018 were included in this study. Medical records were reviewed to obtain clinical and demographic data. Bile specimens were prepared through endoscopic retrograde cholangiopancreatography (ERCP), percutaneous transhepatic cholangiodrainage (PTCD), and percutaneous transhepatic gallbladder drainage (PTGD) under aseptic conditions. In those with positive bile culture results, blood cultures were concurrently conducted. The concordance of the results between bile culture and blood culture were also analysed. Results: Two hundred and sixty-seven bile cultures were positive, while 280 strains of micro-organisms were isolated. Among these, 76.8% were Gram-negative, 22.5% were Gram-positive and 0.7% were fungi. The most common microorganisms were Escherichia coli, Klebsiella pneumoniae, and Enterococcus faecalis. Gram-negative bacteria we tested were highly sensitive to ertapenem, imipenem, tigecycline, and amikacin. Gram-positive bacteria we tested were highly sensitive to tigecycline, teicoplanin, linezolid, vancomycin, and chloramphenicol. For the 44 patients with positive bile cultures, a blood culture was also performed. Among them, 29 cases yielded positive blood culture results. Among those cases with positive blood culture, 48.3% showed complete agreement with bile culture, 3.4% showed partial agreement, and 48.3% showed disagreement. The most common microorganisms in blood culture were the same as in bile culture. Additionally, the proportion of Staphylococcus epidermidis was significantly higher in blood culture (P < 0.05). Conclusion: Our study provided a comprehensive analysis of the bacteria distribution and drug resistance profiles in patients with BTIs in northern China. Further studies should be conducted to validate our findings.
The kinetics and thermodynamics of the enzymatic degradation of zearalenone (ZEN) in degummed corn oil were investigated by analyzing the impacts of temperature, pH, ZEN hydrolase dosage and ZEN concentration on the initial reaction rate. The kinetic study found that the maximum reaction rate was 0.97 µmol × kg−1 min−1, the Michaelis constant (Km) was 11,476 µmol × kg−1 and the Michaelis equation was V = 0.97[S]/(11,476 + [S]). The thermodynamic study showed that the activation energy (Ea) was 70.37 kJ·mol−1, the activation enthalpy change of the reaction (ΔH) > 0, the free energy of activation (ΔG) > 0 and the activation entropy change (ΔS) < 0, indicating the reaction could not be spontaneous. The reaction mechanism of ZEN was studied by a hybrid quadrupole orbitrap mass spectrometer. It was found that ZEN first generated the intermediate G/L/D/W-ZEN+H2O, followed by generating the intermediate W-ZEN-H2O under the action of a degrading enzyme. Then, the lactone bond was opened to produce C18H24O6, and finally the decarboxylation product C17H24O4 formed automatically.
Zearalenone , Zearalenone/analysis , Corn Oil , Thermodynamics , Temperature , Kinetics
Comprehensive investigation of hydrological processes associated with landscape ecology and economic development plays a key role in watershed management, and is less developed in watersheds with large-scale cascade dams. With the abundant hydropower resources and its unprecedented advantages, hydropower exploitation in the upper Yangtze River (Jinsha River) is critical to energy structure adjustment in China. Therefore, we integrated hydrological modeling, landscape ecology analysis, and economic analysis in the dammed Jinsha River. With climate variations in the Jinsha River Basin, the average flow near the uppermost dams in the mainstream grew from 796 m3 s-1 (1990s), to 918 m3 s-1 (2000s), and further to 1025 m3 s-1 (2010s). During 1991 to 2017, the source power in the headwater region grew slightly, but varied little in the downstream area. In the lower dammed Jinsha River, analysis of landscape indicators showed that the landscape was enriched, while the landscape type distribution was more uniform. Moreover, hydropower exploitation brought benefits to regional economic development. Principal component analysis further highlighted the landscape ecological and economic variations with high loadings in the first principal component. With the non-significant temporal variations and normal spatial fluctuations in flow discharge, the landscape pattern was basically stable, and the utilization of hydropower can be sustainable in the Jinsha River. In addition, hydropower development drove local economic development. Based on the integrated analysis of hydrological, landscape ecological, and economic assessment at the watershed scale, our results stressed the significance of hydropower exploitation in the Jinsha River. However, more attention should be paid to the warming climate during hydropower exploitation. These findings are valuable for the scientific planning of hydropower bases in watersheds with large-scale cascade dams, and have substantial implications for sustainable hydropower development.
Glycerol core aldehydes (GCAs) are potentially toxic lipid oxidation products characterized by aldehydic acids bonded to glycerol via acyl groups. This study investigated the profile and change of GCAs in rapeseed oil (RO), high-oleic sunflower oil (HOSO) and cottonseed oil (CO) after frying chicken nuggets (CNs), fish nuggets (FNs) and French fries (FFs) for 60 h in real restaurant frying systems. Three GCAs (8-oxo, 9-oxo, and 10-oxo-8) were identified, with the GCAs (9-oxo) accounting for the highest value (60%), followed by GCAs (10-oxo-8) and GCAs (8-oxo). The total GCAs increased from 1.12 to 2.02 mg/g with frying time from 0 to 60 h in RO used for frying FNs. The FN frying systems produced the largest amount of GCAs, whereas the FF frying systems produced the least. RO contained more GCAs than CO and HOSO owing to its higher unsaturated fatty acid content (91.81%). Furthermore, the GCAs showed a high correlation with polymerized and oxidized products, indicating that the formation of GCAs were related to the oxidative stability of oils. These results may provide insight into the formation of GCAs and their control during frying.
Aldehydes , Glycerol , Animals , Cooking , Fatty Acids/analysis , Restaurants
The search for multiple escaping targets is a significant issue of cooperative control in multi-agent systems since targets consciously seek to avoid being captured. Moreover, the assumption of continuous observations in existing works is not always suitable due to the limit of measuring equipment and uncertain movement of targets. Therefore, the problem with searching for escaping targets, which can be more aptly labeled "multiple escaping-targets search with random observation conditions" (MESROC), is difficult to address by conventional methods. Inspired by machine learning and the immune response mechanism of human bodies, a self-learning immune co-evolutionary network (SLICEN) is proposed. The SLICEN consists mainly of an immune cellular network (ICN) and an immune learning algorithm (ILA). The ICN provides feasible solutions to MESROC. Different kinds of network models are introduced to work as an ICN, such as convolutional neural networks, extreme learning machines, and support vector machines. The ILA evaluates the performance of feasible solutions and selects the optimal ones to further strengthen ICN reversely. Solutions are repeatedly improved through the co-evolution of ICN and ILA. An essential distinction to conventional machine learning approaches is that SLICEN works well without training samples. Simulations and comparisons demonstrate that patterns of advanced cooperative behavior among searchers function properly. SLICEN is an efficient method for solving MESROC.
Indices including conductivity, short-chain carboxylic acids, total polar material, acid value, peroxide value and fatty acid composition in water or oil were monitored during Rancimat test of soybean oil from 90⯰C to 120⯰C. Formic, acetic, propionic and butyric acids in water were detected by ion chromatography. The results showed that all indices had two-stage oxidation rates of initiation (ki) and propagation (kp) at each temperature. Induction period (IP) computed from conductivity and other indices were well correlated (R2â¯=â¯0.9980-0.9999). According to the Arrhenius model and empirical equation, ki increased exponentially with temperature (T) while IP decreased exponentially with T. Oxidation degree of oil at induction time point IP*ki was found to be independent of heating time and temperature. The transition between two models was theoretically derived and proved by H NMR. Evaluation of IP*ki may provide a new route to correlate Rancimat data with shelf life of edible oil.
Hot Temperature , Soybean Oil/chemistry , Oxidation-Reduction , Soybean Oil/metabolism , Time
In the present study, profiles of fatty acid, sn-2 fatty acid, triglyceride, phytochemical (including tocopherol/tocotrienol, phytosterol, flavonoid, carotenoid and polyphenol) and antioxidant capacity of extracts from the whole berry, pulp and seed of Hippophae¨ rhamnoides ssp. yunnanensis were investigated and compared. The distributions of fatty acid, sn-2 fatty acid and triglyceride that was identified using ultra-performance liquid chromatography tandem quadrupole time of flight mass spectrometry (UPLC-Q-TOF/MS) showed obvious differences among the different parts of the ssp. yunnanensis. The whole berry and pulp extracts exhibited high flavonoid, carotenoid and polyphenol contents, whereas, the seed portion expressed high tocopherol/tocotrienol and phytosterol concentrations. Results deduced from this study demonstrated that ssp. yunnanensis is a rich source of unsaturated fatty acid and bioactive minor component, which should be further developed and utilized by breeders and planters.
Antioxidants/isolation & purification , Fruit/chemistry , Hippophae/chemistry , Plant Extracts/chemistry , Seeds/chemistry , Antioxidants/chemistry , Carotenoids/analysis , Chromatography, Liquid , Fatty Acids/analysis , Flavonoids/analysis , Phytochemicals/analysis , Tandem Mass Spectrometry , Triglycerides/analysis
Anodic aluminum oxide (AAO) substrates with a self-ordered triangular array of nanopores provide the means to fabricate multiple forms of nano materials, such as nanowires and nanoparticles. This study focuses on nanostructures that emerge in thin films of metals thermally evaporated onto the surface of AAO. Previous work showed that films of different evaporated metals assume dramatically different structures, e.g. an ordered triangular array of nearly monodisperse nanoparticles forms for lead (Pb) while a polycrystalline nanohoneycomb structure forms for silver (Ag). Here, we present investigations of the effects of substrate temperature and deposition angle that reveal the processes controlling the nano particle array formation. Our findings indicate that arrays form provided the grain nucleation density exceeds the pore density and the atomic mobility is high enough to promote grain coalescence. They introduce a method for producing films with anisotropic grain array structure. The results provide insight into the influence of substrate nano-morphology on thin film growth energetics and kinetics that can be harnessed for creating films with other novel nano-structures.
