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2.
JACC Case Rep ; 29(15): 102440, 2024 Aug 07.
Article in English | MEDLINE | ID: mdl-39157561

ABSTRACT

Mycotic aneurysms and pseudoaneurysms, though rare, present significant diagnostic and therapeutic challenges. The case follows a 74-year-old male with a history of bladder cancer who developed multifocal mycotic aneurysms and pseudoaneurysms following sepsis. Initially misdiagnosed as a Pancoast tumor, imaging revealed an extensive disease involving the right subclavian artery, proximal descending thoracic aorta, infrarenal abdominal aorta, and right common iliac artery. This case highlights the importance of considering mycotic aneurysms in the differential diagnosis of patients with a history of infection and highlights the role of Computed Tomography Angiography in early diagnosis.

3.
Radiol Case Rep ; 19(4): 1413-1418, 2024 Apr.
Article in English | MEDLINE | ID: mdl-38292804

ABSTRACT

Cystic artery pseudoaneurysm (CAP) is a rare entity, with just a few cases reported in the literature. The most common presentation of CAP is described by Quincke's triad of upper gastrointestinal bleeding, jaundice and right upper quadrant abdominal pain. We report the case of an 83-year-old male who presented to the adult emergency with a history of an acute cholecystitis 5 weeks prior for which responded to conservative management. Despite this patient not presenting with Quincke's triad, early suspicion of CAP was considered in light of his history of acute cholecystitis and a computed tomographic CT abdomen ordered promptly which showed a 6 mm cystic artery pseudoaneurysm and a thick-walled gallbladder with surrounding inflammatory changes. Management with an endovascular approach followed by an elective cholecystectomy was done.

4.
J Vasc Bras ; 21: e20210223, 2022.
Article in English | MEDLINE | ID: mdl-35911476

ABSTRACT

Internal thoracic artery aneurysms (ITAAs) are rare with wide variation in clinical presentation and a high risk of rupture. Endovascular techniques are increasingly being used for treatment of such aneurysms over surgical repair in recent times. A 34-year-old male presented with progressive swelling of the right anterior chest wall for 2 weeks and was diagnosed with right internal thoracic artery aneurysm with contained rupture. He underwent successful endovascular repair with coil embolization of ruptured right ITAA. Post intervention computed tomography (CT) angiography confirmed sealing of the ruptured aneurysm with no residual filling of the sac. At six months follow-up he is doing well with complete resolution of hematoma. This case demonstrates that an endovascular approach with coil embolization is a feasible and safe option for treating the rare ruptured ITAAs.


Os aneurismas da artéria torácica interna (ITAAs) são raros, com ampla variação na apresentação clínica e alto risco de ruptura. As técnicas endovasculares têm sido cada vez mais utilizadas para o tratamento desses aneurismas em relação ao reparo cirúrgico. Um homem de 34 anos de idade apresentou edema progressivo da parede torácica anterior direita por 2 semanas e foi diagnosticado com aneurisma da artéria mamária interna direita com ruptura contida. Ele foi submetido a reparo endovascular bem-sucedido, com embolização de ITAA direito roto. A angiotomografia computadorizada (angioTC) pós-intervenção confirmou o selamento do aneurisma rompido, sem enchimento residual do saco. No seguimento de 6 meses, ele estava bem, com resolução completa do hematoma. Este caso demonstra que a abordagem endovascular com embolização com molas é uma opção viável e segura no tratamento dos raros ITAAs rotos.

6.
Rev. Assoc. Med. Bras. (1992, Impr.) ; Rev. Assoc. Med. Bras. (1992, Impr.);68(3): 413-416, Mar. 2022. tab
Article in English | LILACS-Express | LILACS | ID: biblio-1376122

ABSTRACT

SUMMARY OBJECTIVE: The aim of this study was to investigate the frequency of aortic arch anomaly in COVID-19 patients and to determine whether it will be included in the risk classification. METHODS: The study was retrospectively conducted in a third-level hospital by scanning the contrast-enhanced thoracic computed tomography and thoracic computed tomography angiography examinations of patients who received PCR (+), hospitalization, and known COVID pneumonia between March 2020 and July 2021. The study consists of 88 cases and 88 control groups. RESULTS: The study found that the frequency of aortic arch anomaly was higher in patients with COVID-19 pneumonia and in male patients with bovine-type anomaly. CONCLUSIONS: The higher prevalence of bovine arch anomaly in COVID patients may be considered a risk factor for COVID-19 in individuals with this type of vascular anomaly.

7.
Crit Care ; 26(1): 1, 2022 01 03.
Article in English | MEDLINE | ID: mdl-34980198

ABSTRACT

BACKGROUND: SARS-CoV-2 seems to affect the regulation of pulmonary perfusion. Hypoperfusion in areas of well-aerated lung parenchyma results in a ventilation-perfusion mismatch that can be characterized using subtraction computed tomography angiography (sCTA). This study aims to evaluate the efficacy of oral sildenafil in treating COVID-19 inpatients showing perfusion abnormalities in sCTA. METHODS: Triple-blinded, randomized, placebo-controlled trial was conducted in Chile in a tertiary-care hospital able to provide on-site sCTA scans and ventilatory support when needed between August 2020 and March 2021. In total, 82 eligible adults were admitted to the ED with RT-PCR-confirmed or highly probable SARS-COV-2 infection and sCTA performed within 24 h of admission showing perfusion abnormalities in areas of well-aerated lung parenchyma; 42 were excluded and 40 participants were enrolled and randomized (1:1 ratio) once hospitalized. The active intervention group received sildenafil (25 mg orally three times a day for seven days), and the control group received identical placebo capsules in the same way. Primary outcomes were differences in oxygenation parameters measured daily during follow-up (PaO2/FiO2 ratio and A-a gradient). Secondary outcomes included admission to the ICU, requirement of non-invasive ventilation, invasive mechanical ventilation (IMV), and mortality rates. Analysis was performed on an intention-to-treat basis. RESULTS: Totally, 40 participants were enrolled (20 in the placebo group and 20 in the sildenafil group); 33 [82.5%] were male; and median age was 57 [IQR 41-68] years. No significant differences in mean PaO2/FiO2 ratios and A-a gradients were found between groups (repeated-measures ANOVA p = 0.67 and p = 0.69). IMV was required in 4 patients who received placebo and none in the sildenafil arm (logrank p = 0.04). Patients in the sildenafil arm showed a significantly shorter median length of hospital stay than the placebo group (9 IQR 7-12 days vs. 12 IQR 9-21 days, p = 0.04). CONCLUSIONS: No statistically significant differences were found in the oxygenation parameters. Sildenafil treatment could have a potential therapeutic role regarding the need for IMV in COVID-19 patients with specific perfusion patterns in sCTA. A large-scale study is needed to confirm these results. TRIAL REGISTRATION: Sildenafil for treating patients with COVID-19 and perfusion mismatch: a pilot randomized trial, NCT04489446, Registered 28 July 2020, https://clinicaltrials.gov/ct2/show/NCT04489446 .


Subject(s)
COVID-19 Drug Treatment , COVID-19 , Sildenafil Citrate , Vasodilator Agents , Administration, Oral , Adult , Aged , COVID-19/physiopathology , Female , Humans , Male , Middle Aged , Pilot Projects , Sildenafil Citrate/administration & dosage , Treatment Outcome , Vasodilator Agents/administration & dosage , Ventilation-Perfusion Ratio
8.
J. Vasc. Bras. (Online) ; J. vasc. bras;21: e20210223, 2022. graf
Article in English | LILACS | ID: biblio-1386119

ABSTRACT

Abstract Internal thoracic artery aneurysms (ITAAs) are rare with wide variation in clinical presentation and a high risk of rupture. Endovascular techniques are increasingly being used for treatment of such aneurysms over surgical repair in recent times. A 34-year-old male presented with progressive swelling of the right anterior chest wall for 2 weeks and was diagnosed with right internal thoracic artery aneurysm with contained rupture. He underwent successful endovascular repair with coil embolization of ruptured right ITAA. Post intervention computed tomography (CT) angiography confirmed sealing of the ruptured aneurysm with no residual filling of the sac. At six months follow-up he is doing well with complete resolution of hematoma. This case demonstrates that an endovascular approach with coil embolization is a feasible and safe option for treating the rare ruptured ITAAs.


Resumo Os aneurismas da artéria torácica interna (ITAAs) são raros, com ampla variação na apresentação clínica e alto risco de ruptura. As técnicas endovasculares têm sido cada vez mais utilizadas para o tratamento desses aneurismas em relação ao reparo cirúrgico. Um homem de 34 anos de idade apresentou edema progressivo da parede torácica anterior direita por 2 semanas e foi diagnosticado com aneurisma da artéria mamária interna direita com ruptura contida. Ele foi submetido a reparo endovascular bem-sucedido, com embolização de ITAA direito roto. A angiotomografia computadorizada (angioTC) pós-intervenção confirmou o selamento do aneurisma rompido, sem enchimento residual do saco. No seguimento de 6 meses, ele estava bem, com resolução completa do hematoma. Este caso demonstra que a abordagem endovascular com embolização com molas é uma opção viável e segura no tratamento dos raros ITAAs rotos.


Subject(s)
Humans , Male , Adult , Aneurysm, Ruptured/therapy , Embolization, Therapeutic , Endovascular Procedures , Mammary Arteries/diagnostic imaging , Computed Tomography Angiography
10.
Int. j. morphol ; 39(5): 1331-1336, oct. 2021. ilus, tab
Article in English | LILACS | ID: biblio-1385487

ABSTRACT

SUMMARY: The objective of this study was to evaluate the role of the variations of carotid artery course on the relationship between styloid process (SP) and internal carotid artery (ICA). Carotid CT angiography scans of 170 patients were retrospectively evaluated. The variability of the course of ICA were classified. The length and medial angulation of the SP were measured on coronal 3D images. On axial images, the shortest distance between the bone edge of the SP and ICA were measured. The distance between SP and ICA among the course patterns of carotid artery were compared statistically. In the comparison of distances between SP and ICA with respect to the course of ICA, the difference between straight and curving (p <0.001) was statistically significant. Curving caused the separation of ICA and SP. The highest and the shortest distance was at the curving and coiling group, respectively. We found that SP-ICA distance has a positive and negative correlation with SP angle (p<0.001) and SP length (p<0.001), respectively. The course of ICA is one of the major determinants affecting the relationship of ICA and SP. The curving pattern of ICA has a tendency to increase the distance between SP and ICA.


RESUMEN: El objetivo de este estudio fue evaluar el rol de las variaciones que tiene el curso de la arteria carótida en la relación entre el proceso estiloides (PE) y la arteria carótida interna (ACI). Se evaluaron retrospectivamente angiografías por tomografía computarizada carotídea de 170 pacientes. Se clasificó la variabilidad del curso de ACI. Se midieron en imágenes coronales y en 3D la longitud y la angulación medial del PE. En las imágenes axiales, se midió la distancia más corta entre el margen del PE y la ACI. Se comparó estadísticamente la distancia entre PE y la ACI entre los patrones de trayecto de la arteria carótida. La comparación de las distancias entre PE y la ACI respecto al curso de ACI, fue estadísticamente significativa, siendo la diferencia entre arterias recta y curva (p <0,001). La arteria curva provocó la separación de la ACI y del PE. Las mayores y menores distancias estaban en el grupo de arterias curvas y enrolladas, respectivamente. La distancia PE-ACI tiene una correlación positiva y negativa con el ángulo PE (p <0,001) y la longitud del PE (p <0,001), respectivamente. El curso de la arteria carótida interna es uno de los principales determinantes que afectan la relación con el proceso estiloides. El patrón de curva de la ACI tiende a aumentar la distancia entre PE y la propia arteria arteria.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Temporal Bone/anatomy & histology , Temporal Bone/diagnostic imaging , Carotid Artery, Internal/anatomy & histology , Carotid Artery, Internal/diagnostic imaging , Anatomic Variation , Computed Tomography Angiography
11.
Braz J Cardiovasc Surg ; 34(3): 297-304, 2019 06 01.
Article in English | MEDLINE | ID: mdl-31310468

ABSTRACT

OBJECTIVES: To investigate the association between clinical hematologic parameters and saphenous vein graft failure after on-pump coronary artery bypass surgery. METHODS: A total of 1950 consecutive patients underwent isolated on-pump coronary artery surgery between November 2010 and February 2013. Of these, 284 patients met our inclusion criteria; their preoperative clinical hematological parameters were retrospectively obtained for this cohort study. And of them, 109 patients underwent conventional coronary angiography after graft failure was revealed by coronary computed tomography angiography. The primary endpoint was to catch at least one saphenous vein graft stenosis or occlusion following the coronary angiogram. We then analyzed risk factors for graft failure. In sequential or T grafts, each segment was analyzed as a separate graft. RESULTS: In logistic regression analysis, older age, platelet distribution width, and diabetes mellitus were identified as independent predictors of saphenous vein graft failure (P<0.). In contrast, preserved ejection fraction value favored graft patency (P<0.001). CONCLUSION: Increased platelet distribution width is easily measurable and can be used as a simple and valuable marker in the prediction of saphenous vein graft failure.


Subject(s)
Blood Platelets/physiology , Coronary Artery Bypass/adverse effects , Saphenous Vein/transplantation , Vascular Patency/physiology , Adult , Age Factors , Aged , Aged, 80 and over , Coronary Angiography/methods , Coronary Artery Bypass/methods , Coronary Artery Disease/etiology , Echocardiography , Female , Hematologic Tests , Humans , Logistic Models , Male , Middle Aged , Platelet Count , Predictive Value of Tests , ROC Curve , Reference Values , Retrospective Studies , Risk Factors , Saphenous Vein/physiopathology , Statistics, Nonparametric , Treatment Failure
12.
Rev. bras. cir. cardiovasc ; Rev. bras. cir. cardiovasc;34(3): 297-304, Jun. 2019. tab, graf
Article in English | LILACS | ID: biblio-1013476

ABSTRACT

Abstract Objectives: To investigate the association between clinical hematologic parameters and saphenous vein graft failure after on-pump coronary artery bypass surgery. Methods: A total of 1950 consecutive patients underwent isolated on-pump coronary artery surgery between November 2010 and February 2013. Of these, 284 patients met our inclusion criteria; their preoperative clinical hematological parameters were retrospectively obtained for this cohort study. And of them, 109 patients underwent conventional coronary angiography after graft failure was revealed by coronary computed tomography angiography. The primary endpoint was to catch at least one saphenous vein graft stenosis or occlusion following the coronary angiogram. We then analyzed risk factors for graft failure. In sequential or T grafts, each segment was analyzed as a separate graft. Results: In logistic regression analysis, older age, platelet distribution width, and diabetes mellitus were identified as independent predictors of saphenous vein graft failure (P<0.). In contrast, preserved ejection fraction value favored graft patency (P<0.001). Conclusion: Increased platelet distribution width is easily measurable and can be used as a simple and valuable marker in the prediction of saphenous vein graft failure.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Aged, 80 and over , Saphenous Vein/transplantation , Blood Platelets/physiology , Vascular Patency/physiology , Coronary Artery Bypass/adverse effects , Platelet Count , Reference Values , Saphenous Vein/physiopathology , Coronary Artery Disease/etiology , Echocardiography , Logistic Models , Coronary Artery Bypass/methods , Predictive Value of Tests , Retrospective Studies , Risk Factors , ROC Curve , Age Factors , Coronary Angiography/methods , Treatment Failure , Statistics, Nonparametric , Hematologic Tests
13.
Acta Radiol ; 60(4): 459-467, 2019 Apr.
Article in English | MEDLINE | ID: mdl-30060671

ABSTRACT

BACKGROUND: Regional fat density assessed by computed tomography (CT) has been suggested as a marker of perivascular adipose tissue inflammation. Dual energy CT (DECT) allows improved tissue characterization compared to conventional CT. PURPOSE: To explore whether DECT might aid regional fat density discrimination. MATERIAL AND METHODS: We included patients who had completed a non-enhanced cardiac CT scan, CT coronary angiography (CTCA), and a delayed enhancement CT. Attenuation levels (Hounsfield units [HU]) were assessed at the epicardial, paracardial, visceral, and subcutaneous fat. The number of coronary segments with disease (SIS) was calculated. RESULTS: A total of 36 patients were included in the analysis. Twenty-six (72%) patients had evidence of obstructive disease at CCTA and 25 (69%) patients had evidence of previous myocardial infarction. At non-contrast CT, we did not identify significant attenuation differences between epicardial, paracardial, subcutaneous, and visceral fat depots (-110.8 ± 9 HU, vs. -113.7 ± 9 HU, vs. -114.7 ± 8 HU, vs. -113.8 ± 11 HU, P = 0.36). Significant attenuation differences were detected between fat depots at mid and low energy levels, both at CTCA and delayed-enhancement scans ( P < 0.05 for all). Epicardial fat showed the least negative attenuation, irrespective of the acquisition mode; epicardial fat evaluated at 40 keV was related to the SIS (r = 0.37, P = 0.03). CONCLUSIONS: In this study, regional fat depots amenable to examination during thoracic CT scans have distinctive regional attenuation values. Furthermore, such differences were better displayed using contrast-enhanced monochromatic imaging at low energy levels.


Subject(s)
Adipose Tissue/diagnostic imaging , Computed Tomography Angiography/methods , Contrast Media , Coronary Angiography/methods , Coronary Artery Disease/diagnostic imaging , Radiographic Image Enhancement/methods , Female , Humans , Male , Middle Aged , Prospective Studies , Retrospective Studies
14.
Rev. habanera cienc. méd ; 17(5): 720-727, set.-oct. 2018. graf
Article in Spanish | LILACS, CUMED | ID: biblio-985619

ABSTRACT

Introducción: La colitis isquémica es la forma más común de isquemia intestinal. Es más frecuente en pacientes mayores de 65 años y están reconocidos los factores de riesgo de la enfermedad. Objetivo: Considerar el diagnóstico precoz de la enfermedad, mediante la realización de estudios diagnósticos determinados, en un paciente en quien se identifican factores de riesgo para la enfermedad. Presentación del caso: Se presenta un paciente con rectorragia. Al interrogatorio y examen físico se recogen factores de riesgo para la colitis isquémica. El diagnóstico se confirma por colonoscopía y las pruebas radiológicas ayudan a establecer la causa y el lugar de la isquemia. Conclusiones: El reconocimiento de factores de riesgo para la colitis isquémica permitió la sospecha de la enfermedad. Las pruebas diagnósticas, realizadas en un período precoz confirmaron el diagnóstico y permitieron buena respuesta al tratamiento(AU)


Introduction: Ischemic colitis is the most common form of intestinal ischemia. It is frequently observed in patients older than 65 years, and the risk factors of the disease are already known. Objective: To consider the early diagnosis of the disease in a patient in whom risk factors for the disease are identified after performing specific diagnostic tests. Case Presentation: A patient with rectal bleeding is presented. On questioning and physical examination, risk factors for ischemic colitis are identified. The diagnosis is confirmed by colonoscopy, and the radiological tests permitted to identify the cause and location of the ischemia. Conclusions: The identification of risk factors for ischemic colitis allowed to think on the possibility of the disease. Diagnostic tests, performed in an early period, confirmed the diagnosis and made a good response to treatment possible(AU)


Subject(s)
Humans , Male , Aged , Colitis, Ischemic/diagnosis , Early Diagnosis , Computed Tomography Angiography/methods
15.
Rev. chil. radiol ; 24(3): 94-104, jul. 2018. ilus
Article in Spanish | LILACS | ID: biblio-978162

ABSTRACT

La hemorragia subaracnoidea (HSA) no traumática es un subtipo de ictus hemorrágico que representa aproximadamente el 5% de todos los accidentes vasculares encefálicos (AVE). El 85% de los casos de HSA espontánea (no traumática) son secundarios a un aneurisma intracraneano roto, el 10% a hemorragia perimesencefálica no aneurismática y el otro 5% a otras causas. Entre estas se incluyen malformaciones arterio-venosas, fístulas durales, vasculits, trombosis de vena cortical, síndrome de vasoconstricción reversible, angiopatía amiloidea y síndrome de encefalopatía posterior reversible. La aproximación inicial a una HSA no traumática requiere un estudio angiográfico no invasivo con tomografía computada para la toma de decisiones terapéuticas. Si no se detecta un aneurisma sacular intradural que explique el sangrado, las conductas a seguir dependerán del patrón de distribución de la sangre. En esta revisión sugerimos una aproximación basada en 1) revisar el estudio inicial tomando en cuenta los puntos ciegos para la detección de aneurismas, 2) analizar el patrón de distribución de la sangre y 3) analizar los hallazgos en imágenes de acuerdo a las posibles causas según patrón.


Non-traumatic subarachnoid hemorrhage represents approximately 5% of strokes. From these, 85% of nontraumatic subarachnoid hemorrhage are secondary to a ruptured aneurysm, 10% to nonaneurysmal perimesencephalic hemorrhage and the other 5% to other causes. These include but are not limited to arteriovenous malformations, dural fistulae, vasculitis, cortical vein thrombosis, reversible cerebral vasoconstriction syndrome, amyloid angiopathy and posterior reversible encephalopathy syndrome. Initial workup of nontraumatic subarachnoid hemorrhage requires a non-enhanced CT and CT angiography for decision making and management. If there is no aneurysm as a source of hemorrhage, subsequent imaging studies will depend on blood distribution pattern. In this review we suggest an approach: 1) review blind spots for aneurysm detection in the initial CT angiography, 2) analyze blood distribution pattern and 3) evaluate imaging findings and possible causes according to each pattern.


Subject(s)
Humans , Subarachnoid Hemorrhage/etiology , Subarachnoid Hemorrhage/diagnostic imaging , Vasculitis/complications , Intracranial Aneurysm/complications , Cerebral Amyloid Angiopathy/complications , Venous Thrombosis/complications , Computed Tomography Angiography
16.
J Vasc Surg ; 68(6): 1782-1787, 2018 12.
Article in English | MEDLINE | ID: mdl-29914831

ABSTRACT

OBJECTIVE: The increasing use of computed tomography (CT) angiography has led to more frequent diagnoses of celiac artery compression (CAC) by the median arcuate ligament (MAL). The signs of CAC by the MAL have been described as stenosis and a hook or J appearance on sagittal views. The importance of the "hook signal," however, has not been documented by studies of the normal anatomy of the celiac axis. METHODS: CT angiography images of 344 completely asymptomatic, live kidney donors (without history of chronic abdominal pain or weight loss) were reviewed. The angle of emergence (AE) of the celiac axis from the aorta and the angle of upward or downward shifting of the celiac axis before its first branch (fold angle [FA]) were measured. Weight, height, and body mass index were obtained from our electronic database, and correlations with the angles measured were tested. The occurrence of stenosis >50% at the origins of the celiac axis was also determined in the sample. RESULTS: Measurements were possible in 321 cases. The celiac axis was found to leave the aorta at an angle of <90 degrees in all patients (AE range, 7-83 degrees) and <45 degrees in 292 (90%) patients. The FA ranged from 66 to 208 degrees. Before the first branch, the celiac trunk shifted upward in 306 (95%) patients, remained straight in just one of them, and shifted downward in 14 (4%). The AE was positively correlated with weight in women. The FA was negatively correlated with weight in men and women. Body mass index was positively correlated with AE and negatively correlated with FA in both men and women. In 11 cases (3.4%), stenosis >50% was found at the origin of the celiac axis. In only two patients, the celiac axis had an upward slope after the stenosis, which could be interpreted as a hook shape. CONCLUSIONS: The normal anatomy of the celiac axis, when seen on CT angiography images, demonstrates that it exits the aorta downward and then shifts upward. This hook or J shape should not be interpreted as resulting from external compression. CAC by the MAL occurs in 3.42% of the normal asymptomatic population; a hook or J shape is not visible in most cases in that subgroup.


Subject(s)
Aortography/methods , Celiac Artery/diagnostic imaging , Computed Tomography Angiography , Median Arcuate Ligament Syndrome/diagnostic imaging , Adult , Aged , Brazil/epidemiology , Constriction, Pathologic , Female , Humans , Male , Median Arcuate Ligament Syndrome/epidemiology , Middle Aged , Predictive Value of Tests , Prevalence , Retrospective Studies , Young Adult
17.
J Stroke Cerebrovasc Dis ; 25(6): 1417-20, 2016 Jun.
Article in English | MEDLINE | ID: mdl-27021041

ABSTRACT

BACKGROUND: The investigation of ischemic stroke etiology is commonly limited to the heart and extracranial vessels. Nevertheless, the diagnosis of intracranial stenosis may carry important therapeutic implications. The aims of this study were to determine the prevalence and clinical predictors of intracranial atherosclerotic stenosis (ICAS) in a sample of patients with ischemic stroke. METHODS: Consecutive patients admitted to a university-based outpatient stroke clinic underwent CT angiography of the intracranial and extracranial brain vessels. Clinical, demographic, and laboratory characteristics were compared between patients with increasing levels of stenosis. Ankle-brachial index (ABI) was measured to quantify peripheral arterial disease, defined as an ABI less than or equal to .9. Multivariable ordinal logistic regression was constructed to predict increasing stenosis grades (none, 1%-49%-mild, 50%-69%-moderate, 70%-100%-severe). RESULTS: We studied 106 subjects, mean age 62 ± 15 years, 54% female. ICAS was present in 38 (36%) patients: 19 (50%) mild, 7 (18%) moderate, and 12 (32%) severe. Of 74 patients where ABI was measured, low ABI was found more frequently with increasing ICAS severity (26%, 42%, 67%, and 89% of patients with none, mild, moderate, and severe ICAS, respectively). In univariable analysis, higher age, presence of diabetes, abdominal obesity, and low ABI correlated with increasing stenosis grades. In multivariable analysis, only low ABI remained independently associated with increasing stenosis grades. CONCLUSIONS: The ABI is independently associated with increasing severity of ICAS, making it a potentially useful triaging tool for more invasive test selection.


Subject(s)
Ankle Brachial Index , Brain Ischemia/epidemiology , Intracranial Arteriosclerosis/diagnosis , Peripheral Arterial Disease/diagnosis , Stroke/epidemiology , Aged , Brain Ischemia/diagnostic imaging , Brain Ischemia/physiopathology , Brazil/epidemiology , Cerebral Angiography/methods , Cerebrovascular Circulation , Computed Tomography Angiography , Cross-Sectional Studies , Female , Humans , Intracranial Arteriosclerosis/diagnostic imaging , Intracranial Arteriosclerosis/epidemiology , Intracranial Arteriosclerosis/physiopathology , Logistic Models , Male , Middle Aged , Multivariate Analysis , Outpatient Clinics, Hospital , Peripheral Arterial Disease/epidemiology , Peripheral Arterial Disease/physiopathology , Predictive Value of Tests , Prevalence , Risk Assessment , Risk Factors , Severity of Illness Index , Stroke/diagnostic imaging , Stroke/physiopathology
18.
P R Health Sci J ; 35(1): 16-9, 2016 Mar.
Article in English | MEDLINE | ID: mdl-26932279

ABSTRACT

OBJECTIVE: The objective of this study was to determine the diagnostic yield of pulmonary CT angiography (PCTA) in the evaluation of pulmonary embolisms treated at the Puerto Rico Medical Center from 2008 to 2012. METHODS: A total of 1,004 CT angiograms were reviewed in the evaluation of pulmonary embolisms. Patient records covering from 2008 to 2012 were obtained from the picture archiving and communication system (PACS) of the Puerto Rico Medical Center. Follow-up studies and those of pediatric patients were excluded from the study. The results were recorded as either positive or negative for pulmonary embolism, according to the final report rendered by board-certified radiologists. RESULTS: Of the 1,004 patient records reviewed, 964 were included in the study. Forty-six out of the total studies reviewed were positive, while a total of 918 studies were negative. A mean diagnostic yield of 4.8% (SD = 0.63) was obtained. CONCLUSION: At the Puerto Rico Medical Center, the mean diagnostic yield in the evaluation of pulmonary embolism using PCTA was 4.8%, which is in concordance with those of several previous studies, all of which had similar low yields. New diagnostic algorithms for efficiently employing PCTA for the evaluation of pulmonary embolisms are discussed herein.


Subject(s)
Angiography/methods , Multidetector Computed Tomography/methods , Pulmonary Embolism/diagnosis , Humans , Puerto Rico , Retrospective Studies
19.
J Neurotrauma ; 33(11): 1015-22, 2016 06 01.
Article in English | MEDLINE | ID: mdl-26214242

ABSTRACT

Traumatic brain injury (TBI) is the main cause of death in trauma victims and causes high rates of disability and neurological sequelae. Approximately 38-65% of traumatic brain contusions (TBC) demonstrate hemorrhagic expansion on serial computed tomography (CT) scans. Thus far, however, no single variable can accurately predict the hemorrhage expansion of a TBC. Our purpose was to evaluate contrast extravasation (CE) as a predictor of expansion, mortality, and poor outcome in TBC in a Brazilian cohort. After Institutional Review Board approval, we used multidetector CT angiography (MDCTA) to study 121 consecutive patients (106 men, 87.6%) with ages varying from 10 to 85 years. Informed consent was obtained from all subjects. The clinical and imaging findings were correlated with the findings on the initial MDCTA using either the Fisher exact test or Student t test and a multivariate logistic regression model. Of the persons who presented CE in TBC, 21.8% died (in-hospital mortality), whereas in the absence of this sign, the mortality rate was 7.6% (p = 0.014). In addition, expansion of the hemorrhagic component of the TBC was detected in 61.1% of the CE-positive patients, whereas expansion was only observed in 10% of the CE-negative patients (p < 0.001). Poor outcome was observed in 24.2% of the patients in the CE-negative group, but in the presence of CE, 72.7% evolved with poor outcome (p < 0.001). The CE was a strong independent predictor of expansion, poor outcome, and increased risk of in-hospital mortality in our series of patients with TBC.


Subject(s)
Brain Contusion , Cerebral Angiography/methods , Multidetector Computed Tomography/methods , Adolescent , Adult , Aged , Aged, 80 and over , Brain Contusion/diagnostic imaging , Brain Contusion/mortality , Brain Contusion/pathology , Brazil/epidemiology , Child , Female , Hospital Mortality , Humans , Male , Middle Aged , Young Adult
20.
Rev. chil. radiol ; 21(2): 66-69, 2015. ilus
Article in Spanish | LILACS | ID: lil-757194

ABSTRACT

The current treatment for aortic aneurysms is to install an endovascular stent in the aortic lumen. The most common complication of stents is endoleaks. Those defined as a peri-prosthetic vascular leak, in the aneurysm sac, are usually asymptomatic. If not detected early, they can progress with the growth and rupture of the aneurysm. The method of choice for evaluation is angiography by computed tomography (CT). The aim of this pictorial review is to describe and illustrate the imaging findings of the different types of endoleaks in computed tomography angiograms (5 types).


El tratamiento actual de los aneurismas aórticos es la instalación de una endoprótesis en el lumen aórtico por vía endovascular. La complicación más frecuente de las endoprótesis son los endoleaks. Los que se definen como flujo vascular peri-protésico, en el saco aneurismático, generalmente asintomático. De no ser detectados a tiempo, pueden progresar con el crecimiento y rotura del aneurisma. El método de elección para su evaluación es la angiografía mediante tomografía computada (TC). El objetivo de la presente revisión pictográfica es describir e ilustrar los hallazgos imaginológicos de los diferentes tipos de endoleaks en angiografía por tomografía computada (cinco tipos).


Subject(s)
Humans , Aortic Aneurysm , Angiography/methods , Endoleak , Stents/adverse effects , Tomography, X-Ray Computed , Endoleak/classification
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