Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 18 de 18
Filter
1.
Data Brief ; 55: 110536, 2024 Aug.
Article in English | MEDLINE | ID: mdl-38948406

ABSTRACT

This research on human body dimensions offers data for creating comfortable and efficient workplaces. Focusing on Slovak university students (2003-2023) as a representation of the adult population, the study measured 25 key anthropometric dimensions. 11355 respondents (5219 women and 6136 men) were selected for the analysis. This data, analyzed through descriptive statistics, empowers designers to tailor work environments and their elements to individual needs, minimizing worker fatigue and maximizing productivity. The findings are applicable across various design fields: Informing dimensions and functionalities of tools, workspaces, and controls in industrial design and guiding short- and long-term product development in consumer product design. By analyzing future workforce trends through university students, this research helps ensure workplace designs remain relevant and ergonomically sound.

2.
Int J Sports Physiol Perform ; : 1-9, 2024 Jun 11.
Article in English | MEDLINE | ID: mdl-38862109

ABSTRACT

PURPOSE: This study investigated sex differences in self-reported causes, symptoms, and recovery strategies associated with underperformance in endurance athletes. METHODS: A total of 82 athletes (40 women) meeting the inclusion criteria (performance level ≥tier 3, used training diaries, and experienced 1 or more periods of underperformance during their career) completed an online questionnaire. The questionnaire encompassed inquiries regarding load monitoring and experiences with underperformance, focusing on causes, symptoms, and recovery strategies. RESULTS: The most frequently reported symptoms associated with underperformance included psychological (31%), physiological (23%), and health-related (12%) symptoms. Notably, female athletes were more likely to report psychological symptoms associated with underperformance (38% vs 25%, P = .01) compared with male athletes. The leading causes of underperformance comprised illness (21%), mental/emotional challenges (20%), training errors (12%), lack of recovery (10%), and nutritional challenges (5%). Female athletes reported nutritional challenges more frequently as the cause of underperformance compared with males (9% vs 1%, P = .01), whereas male athletes more often attributed underperformance to training errors (15% vs 9%, P = .03). Overall, 67% of athletes reported recovering from underperformance, with a tendency for more male than female athletes to recover (76% vs 58%, P = .07). Furthermore, a higher proportion of male than female athletes reported implementing changes in the training process as a recovery strategy (62% vs 35%, P = .02). CONCLUSIONS: This study offers valuable insights into sex differences in experiences with underperformance in endurance athletes. The findings could inform coaches and athletes in both the prevention and treatment of such incidents.

4.
Front Physiol ; 14: 1288606, 2023.
Article in English | MEDLINE | ID: mdl-38054044

ABSTRACT

Purpose: To compare training characteristics and aerobic power (VO2max) between the most successful junior and senior seasons of world-class cross-country (XC) skiers and to identify differences between sexes and among sprint and distance skiers. Methods: Retrospective analysis was conducted on self-reported training and VO2max tests of ten male and seven female world-class XC-skiers, collectively holding 38 Olympic medals. Training was categorized by form (endurance, strength, speed, other) and mode (specific, unspecific) and was divided into low- (LIT), moderate- (MIT), and high-intensity training (HIT). Results: Total training increased by 203 ± 130 h (35% ± 31%, p < .001, large effect) and 78 ± 69 sessions (21% ± 24%, p < .001, very large effect). Junior training volume (658 ± 107 h) did not correlate with senior volume (861 ± 74 h) but correlated negatively with changes in volume (r = -.822, p < .001). No sex differences were observed related to total volume, but distance skiers increased their total volume more than sprint skiers (p = .037, large effect). Endurance training increased by 197 ± 117 h (p < .001; large effect) tied to increased low-intensity training (186 ± 115 h, p < .001; large effect) and moderate-intensity training (13 ± 7 h, p < .001; large effect). Training intensity distribution (% LIT/MIT/HIT) was 91/3/6 in junior and 92/4/4 in senior season. Women demonstrated greater increase of unspecific modes (100 ± 58 vs. 37 ± 44 h, p = .022; large effect) and strength training (25 ± 23 vs. -3 ± 17 h, p = .010, large effect). Men improved absolute (8% ± 5%; p = .009; large effect) and relative VO2max (6% ± 4%; p = .016; large effect) from junior to senior, while women only increased relative VO2max (7% ± 5%, p = .012; large effect). Conclusion: This study provides novel information regarding changes in training characteristics and aerobic power from junior to senior age in world-class XC-skiers. Overall, the enhanced training volume during this transition was primarily driven by increased LIT and MIT and the exceptionally high relative VO2max at junior age further increased in both sexes.

5.
J Neural Eng ; 20(5)2023 09 19.
Article in English | MEDLINE | ID: mdl-37678214

ABSTRACT

Objective.The purpose of this study is to investigate whether and how the balance between excitation and inhibition ('E/I balance') influences the spontaneous development of human-derived neuronal networksin vitro. To achieve that goal, we performed a long-term (98 d) characterization of both homogeneous (only excitatory or inhibitory neurons) and heterogeneous (mixed neuronal types) cultures with controlled E/I ratios (i.e. E:I 0:100, 25:75, 50:50, 75:25, 100:0) by recording their electrophysiological activity using micro-electrode arrays.Approach.Excitatory and inhibitory neurons were derived from human induced pluripotent stem cells (hiPSCs). We realized five different configurations by systematically varying the glutamatergic and GABAergic percentages.Main results.We successfully built both homogeneous and heterogeneous neuronal cultures from hiPSCs finely controlling the E/I ratios; we were able to maintain them for up to 3 months. Homogeneity differentially impacted purely inhibitory (no bursts) and purely excitatory (few bursts) networks, deviating from the typical traits of heterogeneous cultures (burst dominated). Increased inhibition in heterogeneous cultures strongly affected the duration and organization of bursting and network bursting activity. Spike-based functional connectivity and image-based deep learning analysis further confirmed all the above.Significance.Healthy neuronal activity is controlled by a well-defined E/I balance whose alteration could lead to the onset of neurodevelopmental disorders like schizophrenia or epilepsy. Most of the commonly usedin vitromodels are animal-derived or too simplified and thus far from thein vivohuman condition. In this work, by performing a long-term study of hiPSCs-derived neuronal networks obtained from healthy human subjects, we demonstrated the feasibility of a robustin vitromodel which can be further exploited for investigating pathological conditions where the E/I balance is impaired.


Subject(s)
Induced Pluripotent Stem Cells , Animals , Humans , Cysteamine , Electrodes , Healthy Volunteers , Neurons
6.
Scand J Med Sci Sports ; 33(12): 2444-2456, 2023 Dec.
Article in English | MEDLINE | ID: mdl-37632141

ABSTRACT

OBJECTIVE: The sports-science literature lacks data on training and performance characteristics of international elite athletes over multiple seasons. The present case study provided general training characteristics and performance data of two male short-distance triathletes in the Junior, U23, and international Elite categories. METHODS: General training and performance data of two male elite triathletes were described in swimming, cycling, and running segments from the 2015 to 2022 season. The training load was presented using the ECO model while the training intensity distribution (TID) was a triphasic model. RESULTS: Both triathletes increased their performance throughout the seasons. Triathlete A increased his VO2max in cycling by 20.6%, in running by 16.7%. His power at VO2max and his speed at VO2max by 18.9% and 11.0%, respectively. Triathlete B improved his VO2max by 17.8% in cycling, by 16.1% in running and his power at VO2max by 24%, and his speed at VO2max by 14.3%. The triathletes trained on average 14-17 h a week. The TID model was polarized. CONCLUSIONS: To achieve the top international level, it is necessary to consider the following measures: training load progression; improvements in physiological variables; and participation in international events starting from youth categories.


Subject(s)
Oxygen Consumption , Physical Endurance , Adolescent , Humans , Male , Oxygen Consumption/physiology , Physical Endurance/physiology , Swimming/physiology , Bicycling/physiology
7.
Int J Sports Physiol Perform ; 18(8): 874-877, 2023 Aug 01.
Article in English | MEDLINE | ID: mdl-37244645

ABSTRACT

PURPOSE: The purpose of the current investigation was to retrospectively assess possible differences in physiological performance characteristics between junior cyclists signing a contract with an under-23 (U23) development team versus those failing to sign such a contract. METHODS: Twenty-five male junior cyclists (age: 18.1 [0.7] y, stature: 181.9 [6.0] cm, body mass: 69.1 [7.9] kg, peak oxygen uptake: 71.3 [6.2] mL·min-1·kg-1) were assigned to this investigation. Between September and October of the last year in the junior category, each cyclist performed a ramp incremental exercise test to determine certain physiological performance characteristics. Subsequently, participants were divided in 2 groups: (1) those signing a contract with a U23 development team (JUNIORU23) and (2) those failing to sign such a contract (JUNIORNON-U23). Unpaired t tests were used to assess possible between-groups differences in physiological performance characteristics. The level of statistical significance was set at P < .05 two tailed. RESULTS: No significant between-groups differences in submaximal (ie, gas exchange threshold, respiratory compensation point) and maximal physiological performance characteristics (ie, peak work rate, peak oxygen uptake) expressed in absolute values (ie, L·min-1, W) were observed (P > .05). However, significant between-groups differences were observed when physiological performance characteristics were expressed relative to the cyclists' body weights (P < .05). CONCLUSIONS: The current investigation showed that junior cyclists stepping up to a U23 development team might be retrospectively differentiated from junior cyclists not stepping up based on certain physiological performance characteristics, which might inform practitioners and/or federations working with young cyclists during the long-term athletic development process.


Subject(s)
Athletic Performance , Oxygen Consumption , Humans , Male , Adolescent , Retrospective Studies , Oxygen Consumption/physiology , Bicycling/physiology , Exercise Test , Athletic Performance/physiology , Oxygen
8.
Biol Sport ; 39(3): 621-628, 2022 Sep.
Article in English | MEDLINE | ID: mdl-35959335

ABSTRACT

In rugby union, physical characteristics may partially contribute to long-term career progression, especially during adolescence. Therefore, the primary purpose of the study was to evaluate Italian regional rugby union academy players' (i.e., under-18) anthropometric and physical characteristics during a competitive season. Body mass, height, upper- and lower-body maximal strength, sprint, and high-intensity running ability were assessed in 29 elite players (backs, n = 13, forwards, n = 16). A mixed-design analysis of variance (ANOVA) for repeated measures showed that backs were shorter (ES = 0.59), lighter (ES = 0.94), stronger relative to body mass (bench press; ES = 0.60; deadlift; ES = 0.63; clean ES = 0.63; rowing ES = 0.67), and fitter (shuttle run max; ES = 0.38; shuttle run tot; ES = 0.79) than forwards. However, the forwards achieved greater sprint momentum (initial sprint momentum; ES = 0.97; maximal sprint momentum; ES = 0.98). During the season, players changed in stature, upper-body maximal strength, jumping, and high intensity running (p < 0.05), but not in body weight or lower-body maximal strength (p > 0.05). Maximal strength improved in the first part of the season, whereas jumping and sprinting performances increased in the last part of the season. Therefore, these findings highlight the importance of regularly monitoring the physical development in a long-term perspective, even suggesting that physiological adaptations are heterochronic between positional roles.

9.
Article in English | MEDLINE | ID: mdl-35162444

ABSTRACT

The aims of this study were to investigate the relative and chronological age among taekwondo world medal winners (by gender, Olympic 4-year period, Olympic weight category; N = 740), and to study the behaviour of multiple medallists (N = 156) to monitor changes in weight categories and wins over time. The observed birth quartile distribution for the heavyweight category was significantly skewed (p = 0.01). Female athletes (22.2 ± 3.5 years) achieve success at a significantly younger age (p = 0.01) than their male counterparts (23.6 ± 3.3 years). In the weight categories, female flyweights were significantly younger than those welterweights (p = 0.03) and heavyweight (p = 0.01); female featherweights were significantly younger than those heavyweights (p = 0.03). Male flyweights and featherweights were significantly younger than those welterweights and heavyweights (p = 0.01). When a taekwondo athlete won a medal several times, he/she did so within the same Olympic weight category group and won two medals in his/her career (p = 0.01). Multiple medallists of the lighter and heavier groups did not differ in the number of medals won but in the time span in which they won medals (p = 0.02). The resources deployed by stakeholders to achieve success in these competitions highlight an extremely competitive environment. In this sense, the information provided by this study can be relevant and translated into key elements.


Subject(s)
Awards and Prizes , Martial Arts , Achievement , Adult , Athletes , Competitive Behavior , Female , Humans , Male , Young Adult
10.
Acta Paediatr ; 111(3): 566-575, 2022 Mar.
Article in English | MEDLINE | ID: mdl-34665877

ABSTRACT

AIM: Little is known about the prevalence of discrete white matter abnormalities (WMA) beyond the first years in children born extremely preterm (EPT) and the relation to neurodevelopmental outcomes. Our aim was to investigate the prevalence of discrete WMA in children born EPT and the relationship to neonatal white matter injuries (WMI), white matter (WM) volume, WM diffusivity and neurodevelopment. METHODS: The study was a part of a longitudinal follow-up study of EPT neonates. All children were scanned at Karolinska University hospital 2004-2007 (neonates) and 2014-2015 (children at 8-11 years). WMA was qualitatively assessed by visual inspection. Developmental assessment was conducted at 12 years. RESULTS: In total, 112 children (median age 10.3 years, 56 girls) underwent MRI of the brain (68 EPT, 45 controls). In the EPT group, a subset had MRI around term equivalent age (n = 61). In the EPT group, the prevalence of discrete WMA at 8-11 years was 52%. There was a positive association between WMI at TEA and 8-11 years. There was no association between WMI and WM volumes or diffusivity at 8-11 years. Discrete WMA was not related to neurodevelopmental outcomes. CONCLUSION: Discrete WMA was prevalent in children born EPT at 8-11 years but were not related to neurodevelopmental outcomes.


Subject(s)
White Matter , Brain/diagnostic imaging , Child , Cognition , Female , Follow-Up Studies , Humans , Infant, Extremely Premature , Infant, Newborn , Magnetic Resonance Imaging , White Matter/diagnostic imaging
11.
Front Physiol ; 13: 1023378, 2022.
Article in English | MEDLINE | ID: mdl-36685210

ABSTRACT

The aim of this study was to quantify and compare various external match load measures in three age groups and leagues in male soccer (U18 in highest league of their age group vs U21 in fourth highest league vs first team in highest league). In this retrospective observational cohort study accelerations, decelerations, absolute and relative high-speed running as well as sprint distance, dynamic stress load, explosive distance, high intensity bursts total distance, high metabolic load (HML) distance, speed intensity, total distance, total time, and total loading were assessed in 416 individual player matches of 59 players. All these external load measures showed large inter-individual variability. At a group level, one-way ANOVAs or Kruskal-Wallis tests revealed statistically significant differences between the three teams for all measures analyzed (all p < 0.05), except accelerations. The first team displayed statistically significant higher dynamic stress load, explosive distance, HML distance, speed intensity, total distance and total loading compared to the two youth teams (all p < 0.05). The U18 featured statistically significant higher number of decelerations, absolute and relative high-speed running distance, high metabolic load distance, speed intensity, relative sprint distance, total distance, and total time than the U21, while for U21 higher dynamic stress load was observed than for U18 (all p < 0.05). Based on our data we conclude a routinely monitoring of match loads of different age groups and competitive settings to be required to 1) provide an indication of what players need to be prepared for, 2) track the athletic and match evolution, and 3) individually tailor training programs allowing players to fulfill the short- and long-term sport-specific requirements.

12.
Article in English | MEDLINE | ID: mdl-34205787

ABSTRACT

Developmental problems in extremely preterm (EP) infants and the associated longitudinal burden for their families are major health issues worldwide. Approaches to social-emotional support such as family-integrating Creative Music Therapy (CMT) are warranted. We aimed: (1) to explore parental perspectives on the use of CMT with EP infants in the neonatal hospitalization period and (2) to examine the possible longitudinal influence of CMT. A qualitative design was used to examine the perspective of six families from various backgrounds. Semi-structured interviews were carried out when the infants reached school age. We used an inductive-deductive thematic analysis to identify three main themes, each with three sub-themes: (1) the positive impact of CMT on the infants, the parents, and bonding; (2) the attitude toward CMT, from being open-minded to recommending it as complementary therapy; and (3) the experience of overall healthy infant development despite unique developmental delay issues. The findings elucidate the positive and formative impact of CMT on both infants and parents in the stressful NICU setting and beyond. CMT may empower positive transformation in the parents through individualized early nurturing musical interactions, capacity building, and positive reinforcement. Further research may help to identify and implement potentially modifiable factors for improving health care in this vulnerable group through early family-integrating, resource-based approaches such as CMT.


Subject(s)
Music Therapy , Music , Child , Child Development , Follow-Up Studies , Humans , Infant , Infant, Extremely Premature , Infant, Newborn , Intensive Care Units, Neonatal , Qualitative Research
13.
Front Psychol ; 10: 1677, 2019.
Article in English | MEDLINE | ID: mdl-31379689

ABSTRACT

Optimizing basketball performance during the stages of long-term athlete development require to identify the trainability and variation of specific technical skills, when adjusting for anthropometric changes. The aim of this study was to describe differences in height, body mass, arm span, and technical-related fitness (movement, dribbling, shooting) along the long-term development of 7-17 years Lithuanian basketball players. This cross-sectional analysis involved a total of 1051 basketball players from the Sabonis Basketball Center in Lithuania. Testing sessions were performed during 1 day of the competition period in an indoor court. The participants performed technical-related fitness tests to assess dribbling (control dribble, 20 m dribble, two balls of 20 m dribble, Illinois agility dribble), shooting (30 free-throw shoots, 1 min shooting, modified medium and long-range shots, close range shots) and defensive movements. The dribbling skills had substantial improvements (7 to 8-years-old: 20 m sprint with dribbling, effect size = 1.86; control dribble effect size = 2.18; 9 to 10-year-old: 20 m sprint with dribbling, effect size = 1.85; Illinois agility test with dribbling effect size = 1.82). Changes in defensive movement occurred mostly at the 14-15-age period. The best periods to develop dribbling and shooting skills were between 7-10 and 12-13 years, whereas defensive movements can be trained in later adolescent years. Current results and consequent normative profiles, presented as percentile tables, allow to accurately follow the players' development.

14.
Acta Obstet Gynecol Scand ; 98(10): 1227-1234, 2019 10.
Article in English | MEDLINE | ID: mdl-31091336

ABSTRACT

INTRODUCTION: Recent recommendations characterize deliveries at 37+0  weeks through 38+6  weeks as early term. We aimed to review the literature systematically on long-term cognition, school performance and behavior in children born early term (37+0 to 38+6 weeks) compared with full term (39+0  to 40+6 weeks). MATERIAL AND METHODS: The review was performed according to the PRISMA Statement. The final literature search was performed on 31 January 2019. We located studies in PubMed, Embase, CINAHL and Cochrane Library. Eligible studies were randomized controlled trials, cohort studies and case-control studies, with outcome assessment performed at 2-19 years. We collected information using a structured data form and evaluated study quality using the Newcastle-Ottawa Scale (NOS). RESULTS: We included 42 observational studies published between 2006 and 2018. No restriction on year of publication was made. The mean NOS score was 5.8 with a range from 3 to 9. Compared with children born full term, children born early term had a lower intelligence score in early adulthood and up to some 30% increased risk of attention-deficit/hyperactivity disorder. Furthermore, we found some 10%-40% increased risk of cognitive problems, some 25% higher risk of language impairments and another 8%-75% with poorer overall school performance. No meta-analysis was conducted due to heterogeneity in the outcome measures. Only 10 studies presented subgroup analyses in spontaneous deliveries or adjusted for type of labor onset/induction. CONCLUSIONS: Children born early term are at increased risk of cognitive deficits, poorer school performance and behavioral problems compared with children born full term.


Subject(s)
Child Behavior Disorders , Cognition Disorders , Educational Status , Gestational Age , Infant, Premature , Adolescent , Child , Child, Preschool , Female , Humans , Infant , Infant, Newborn , Pregnancy , Pregnancy Trimester, Third , Prognosis , Risk Factors
15.
Gait Posture ; 61: 215-219, 2018 03.
Article in English | MEDLINE | ID: mdl-29413787

ABSTRACT

BACKGROUND: Femoral derotation osteotomy (FDO) is the standard treatment for internal rotation gait (IRG) in children with cerebral palsy (CP) although high rates of recurrence have been reported recently. Various factors associated with recurrence could be identified, but no predictor named. RESEARCH QUESTIONS: Does FDO lead to a change of internal transversal hip moments? Are preoperative internal transversal hip moments a predictor for recurrence of IRG? METHODS: 41 children with spastic bilateral CP and 72 limbs that received a FDO (10.4 ±â€¯2.7 years at surgery) were included retrospectively. Kinematic data were analyzed pre- (2 ±â€¯3 months), postoperatively (12 ±â€¯3 months) and at long-term follow-up (at least five years postoperatively; 84 ±â€¯13 months), internal transversal hip moments were analyzed pre- and postoperatively. RESULTS: The maximum peaks of the internal hip rotation moment during loading response decreased significantly (p = 0.003). The minimum during the second half of the stance phase increased significantly (p = 0.004) and the initially internal externally rotating moment changed to an internal internally rotating moment. No correlation between changes in hip rotation from postoperatively to the long-term follow-up and the preoperative internal hip rotation moment could be identified. SIGNIFICANCE: FDO leads to changes in internal hip rotation moments. Preoperative internal hip rotation moments can't be used as predicting factor for recurrence of IRG. The data suggest, that recurrence of IRG depends less on patient specific motion patterns, but more on the time point of surgery and the therapy of all concomitant deformities during SEMLS.


Subject(s)
Cerebral Palsy/surgery , Femur/surgery , Gait Disorders, Neurologic/surgery , Hip Joint/physiopathology , Osteotomy/methods , Adolescent , Biomechanical Phenomena , Cerebral Palsy/complications , Child , Child, Preschool , Female , Follow-Up Studies , Gait/physiology , Gait Disorders, Neurologic/physiopathology , Humans , Male , Osteotomy/adverse effects , Postoperative Period , Range of Motion, Articular/physiology , Recurrence , Retrospective Studies , Treatment Outcome
16.
Early Hum Dev ; 90(12): 851-6, 2014 Dec.
Article in English | MEDLINE | ID: mdl-25463831

ABSTRACT

BACKGROUND: The predictive value of the combination of neurological examination and brain magnetic resonance imaging (MRI) or cranial ultrasound (cUS) in preterm infants is not known. AIMS: To study the prognostic value of the combination of neurological examination and brain MRI at term equivalent age (TEA) or serial neonatal cUS in very preterm infants for neurosensory outcome at 2 years of corrected age. STUDY DESIGN: A prospective follow-up study. SUBJECTS: A total of 216 very preterm infants (birth weight 1132 g [SD 331 g]) born in Turku University Hospital, from 2001 to 2006, were included. OUTCOME MEASURES: The Dubowitz neurologic examination and brain MRI were done at TEA, and serial cUS examinations were performed until TEA. The Hammersmith Infant Neurological Examination (HINE) and neurosensory impairments (NSI) were assessed at 2 years of corrected age. RESULTS: Of all infants, 163 (76%) had one or more deviant neurological items at TEA, and 32 (15%) had the HINE total score below the 10th percentile at 2 years of corrected age. A total of 17 (8%) infants had NSI. Neurological examination at TEA improved the negative and positive predictive values of brain MRI for NSI from 99% to 100%, and from 28% to 35%, respectively, and the negative and positive predictive values of cUS from 97% to 100%, and from 61% to 79%, respectively. CONCLUSIONS: The combination of the Dubowitz neurologic examination and the brain MRI at TEA or serial neonatal cUS provides a valuable clinical tool for predicting long-term neurosensory outcome in preterm infants.


Subject(s)
Echoencephalography , Infant, Very Low Birth Weight/physiology , Nervous System Diseases/diagnosis , Neurologic Examination , Child, Preschool , Finland , Follow-Up Studies , Humans , Infant, Newborn , Infant, Premature , Infant, Premature, Diseases , Infant, Very Low Birth Weight/growth & development , Predictive Value of Tests , Prognosis , Prospective Studies
17.
Scand J Psychol ; 55(4): 319-25, 2014 Aug.
Article in English | MEDLINE | ID: mdl-24828950

ABSTRACT

The aim of this article is to investigate the long-term developmental consequences of being born to a substance-using mother, focusing on cognitive functions, attention, emotional and social development. The longitudinal sample comprised 48 adolescents aged 12-16 at the time of follow-up assessments, which included the Wechsler Intelligence Scale for Children-III, the Test of Everyday Attention for Children, The Tower of London test and the Strengths and Difficulties Questionnaire. The adolescents scored significantly lower than the norms on Wechsler's subtests and Full-Scale IQ, and on The Everyday Attention test. There were few differences on the Strengths and Difficulties Questionnaire. The girls reported significantly more hyperactivity than the British norms, and the teachers reported higher impact scores in boys, compared to the British norms. Thus, the results on cognitive consequences of maternal substance use appear to be very substantial while the emotional and social consequences do not. The results suggest serious negative effects of substance exposure in utero on attention and cognitive functioning in general.


Subject(s)
Attention/physiology , Cognition Disorders/psychology , Cognition/physiology , Emotions/physiology , Intelligence/physiology , Prenatal Exposure Delayed Effects/psychology , Substance-Related Disorders/complications , Adolescent , Adolescent Development/physiology , Child , Child of Impaired Parents/psychology , Female , Humans , Male , Neuropsychological Tests , Pregnancy , Social Behavior
18.
Clin Neurophysiol ; 124(9): 1868-80, 2013 Sep.
Article in English | MEDLINE | ID: mdl-23680008

ABSTRACT

OBJECTIVE: We aimed to determine whether long-term cortical auditory development is altered or delayed in children using cochlear implants relative to their normal hearing peers. We hypothesized that cortical development in children using unilateral cochlear implants follows a normal trajectory with long-term auditory input when the duration of bilateral auditory deprivation in childhood is limited. METHODS: Electrically-evoked cortical responses were recorded in 79 children who received one cochlear implant within 2.03 ± 1.36 years of bilateral deafness and had up to ∼16 years of time-in-sound experience, and in 58 peers with normal hearing. Amplitude differences between the responses from children using cochlear implants and with normal hearing were calculated between 0 and 300 ms. RESULTS: Responses from cochlear implant users remain different from those of their normal hearing peers. These differences decreased over time, but were not eliminated even after 10 years of time-in-sound. Specifically, the P(1)-N(1)-P(2)-N(2) complex, typical of a normally mature response, began to emerge by 10 years of time-in-sound experience, but the amplitudes of peaks P(2) and N(2) became abnormally large. CONCLUSION: Mature-like cortical responses emerge in children after long-term unilateral cochlear implant use, however, differences from normal persist. SIGNIFICANCE: Maturation of cortical responses with long-term cochlear implant use potentially underlies functional improvements in hearing. Persistent differences from normal could reflect an increase in attention or multi-sensory processing during listening.


Subject(s)
Auditory Cortex/growth & development , Auditory Perception/physiology , Cochlear Implants/statistics & numerical data , Deafness/physiopathology , Deafness/rehabilitation , Adolescent , Adult , Age of Onset , Child , Child, Preschool , Deafness/epidemiology , Evoked Potentials, Auditory , Female , Follow-Up Studies , Humans , Male , Reaction Time , Young Adult
SELECTION OF CITATIONS
SEARCH DETAIL
...