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1.
J Bodyw Mov Ther ; 39: 454-462, 2024 Jul.
Article in English | MEDLINE | ID: mdl-38876668

ABSTRACT

OBJECTIVES: Anterior cruciate ligament injury is one of the most serious ligamentous injuries. The purpose is to compare the impact of the ankle joint on the knee during landing between athletes with chronic instability and a control group (coper group) and to verify the effects of the kinetic chain from other joints. DESIGN: Prospective study. SETTING: High school basketball. PARTICIPANTS: Participants were 62 female high school basketball players who had participated in team sports for >6 months. MAIN OUTCOME MEASURES: Player joint angles, movements, and moments. RESULTS: The knee valgus moment was significantly higher in the chronic ankle instability group than in the coper group (20%-60% [p < 0.01]; 80%-100% [p < 0.05]) during landing motion. The knee valgus moment was also significantly higher during the change from the maximum knee joint flexion position to the maximum extension (p < 0.05). In addition, the landing motions of the chronic instability group may have utilized suboptimal compensatory motor strategy on the sagittal plane, depending heavily on the knee joint's abduction moment. CONCLUSIONS: Our findings indicate that the chronic ankle instability group uses a different landing strategy pattern than the coper group by changing the joint moment and joint angle during landing, which may increase the risk of anterior cruciate ligament injury.


Subject(s)
Ankle Joint , Basketball , Joint Instability , Knee Joint , Humans , Basketball/physiology , Joint Instability/physiopathology , Female , Adolescent , Ankle Joint/physiopathology , Ankle Joint/physiology , Prospective Studies , Biomechanical Phenomena/physiology , Knee Joint/physiopathology , Knee Joint/physiology , Anterior Cruciate Ligament Injuries/physiopathology , Range of Motion, Articular/physiology , Movement/physiology
2.
Sensors (Basel) ; 24(11)2024 Jun 05.
Article in English | MEDLINE | ID: mdl-38894442

ABSTRACT

Laboratory studies have limitations in screening for anterior cruciate ligament (ACL) injury risk due to their lack of ecological validity. Machine learning (ML) methods coupled with wearable sensors are state-of-art approaches for joint load estimation outside the laboratory in athletic tasks. The aim of this study was to investigate ML approaches in predicting knee joint loading during sport-specific agility tasks. We explored the possibility of predicting high and low knee abduction moments (KAMs) from kinematic data collected in a laboratory setting through wearable sensors and of predicting the actual KAM from kinematics. Xsens MVN Analyze and Vicon motion analysis, together with Bertec force plates, were used. Talented female football (soccer) players (n = 32, age 14.8 ± 1.0 y, height 167.9 ± 5.1 cm, mass 57.5 ± 8.0 kg) performed unanticipated sidestep cutting movements (number of trials analyzed = 1105). According to the findings of this technical note, classification models that aim to identify the players exhibiting high or low KAM are preferable to the ones that aim to predict the actual peak KAM magnitude. The possibility of classifying high versus low KAMs during agility with good approximation (AUC 0.81-0.85) represents a step towards testing in an ecologically valid environment.


Subject(s)
Machine Learning , Soccer , Humans , Female , Biomechanical Phenomena/physiology , Soccer/physiology , Adolescent , Knee Joint/physiology , Anterior Cruciate Ligament Injuries/physiopathology , Movement/physiology , Weight-Bearing/physiology , Wearable Electronic Devices
3.
Scand J Med Sci Sports ; 34(6): e14675, 2024 Jun.
Article in English | MEDLINE | ID: mdl-38864455

ABSTRACT

BACKGROUND: Although individuals with anterior cruciate ligament reconstruction (ACLR) are at high risk for posttraumatic osteoarthritis, mechanisms underlying the relationship between running and knee cartilage health remain unclear. OBJECTIVE: We aimed to investigate how 30 min of running influences femoral cartilage thickness and composition and their relationships with running biomechanics in patients with ACLR and controls. METHODS: Twenty patients with ACLR (time post-ACLR: 14.6 ± 6.1 months) and 20 matched controls participated in the study. A running session required both groups to run for 30 min at a self-selected speed. Before and after running, we measured femoral cartilage thickness via ultrasound imaging. A MRI session consisted of T2 mapping. RESULTS: The ACLR group showed longer T2 relaxation times in the medial femoral condyle at resting compared with the control group (central: 51.2 ± 16.6 vs. 34.9 ± 13.2 ms, p = 0.006; posterior: 50.2 ± 10.1 vs. 39.8 ± 7.4 ms, p = 0.006). Following the run, the ACLR group showed greater deformation in the medial femoral cartilage than the control group (0.03 ± 0.01 vs. 0.01 ± 0.01 cm, p = 0.001). Additionally, the ACLR group showed significant negative correlations between resting T2 relaxation time in the medial femoral condyle and vertical impulse (standardized regression coefficients = -0.99 and p = 0.004) during running. CONCLUSIONS: Our findings suggest that those who are between 6 and 24 months post-ACLR have degraded cartilage composition and their cartilage deforms more due to running vGRF.


Subject(s)
Anterior Cruciate Ligament Reconstruction , Cartilage, Articular , Femur , Magnetic Resonance Imaging , Running , Humans , Cartilage, Articular/diagnostic imaging , Male , Biomechanical Phenomena , Female , Femur/diagnostic imaging , Adult , Running/physiology , Young Adult , Case-Control Studies , Ultrasonography , Anterior Cruciate Ligament Injuries/surgery , Anterior Cruciate Ligament Injuries/physiopathology , Knee Joint/diagnostic imaging , Knee Joint/physiology
4.
PLoS One ; 19(6): e0304511, 2024.
Article in English | MEDLINE | ID: mdl-38848409

ABSTRACT

Change of direction, stops, and pivots are among the most common non-contact movements associated with anterior cruciate ligament (ACL) injuries in soccer. By observing these dynamic movements, clinicians recognize abnormal kinematic patterns that contribute to ACL tears such as increased knee valgus or reduced knee flexion. Different motions and physical demands are observed across playing positions, which may result in varied lower limb kinematic patterns. In the present study, 28 college and sub-elite soccer players performed four dynamic motions (change of direction with and without ball, header, and instep kick) with the goal of examining the effect of on-field positioning, leg dominance, and gender in lower body kinematics. Motion capture software monitored joint angles in the knee, hip, and ankle. A three-way ANOVA showed significant differences in each category. Remarkably, centrally positioned players displayed significantly greater knee adduction (5° difference, p = 0.013), hip flexion (9° difference, p = 0.034), hip adduction (7° difference, p = 0.016), and dorsiflexion (12° difference, p = 0.022) when performing the instep kick in comparison to their laterally positioned counterparts. These findings suggest that central players tend to exhibit a greater range of motion when performing an instep kicking task compared to laterally positioned players. At a competitive level, this discrepancy could potentially lead to differences in lower limb muscle development among on-field positions. Accordingly, it is suggested to implement position-specific prevention programs to address these asymmetries in lower limb kinematics, which can help mitigate dangerous kinematic patterns and consequently reduce the risk of ACL injury in soccer players.


Subject(s)
Lower Extremity , Soccer , Humans , Soccer/physiology , Biomechanical Phenomena , Male , Female , Young Adult , Lower Extremity/physiology , Adult , Anterior Cruciate Ligament Injuries/physiopathology , Range of Motion, Articular/physiology , Knee Joint/physiology , Adolescent , Athletes , Ankle Joint/physiology , Hip Joint/physiology
5.
Clin Biomech (Bristol, Avon) ; 116: 106286, 2024 Jun.
Article in English | MEDLINE | ID: mdl-38850881

ABSTRACT

BACKGROUND: The aim of this study was to test the hypothesis that proinflammatory cytokines correlate with knee loading mechanics during gait following a mechanical walking stimulus in subjects 2 years after anterior cruciate ligament reconstruction. Elevated systemic levels of proinflammatory cytokines can be sustained for years after injury. Considering roughly 50% of these patients progress to Osteoarthritis 10-15 years after injury, a better understanding of the role of proinflammatory cytokines such as tumor necrosis factor-α and Interleukin-1ß on Osteoarthritis risk is needed. METHODS: Serum proinflammatory cytokines concentrations were measured in 21 subjects 2 years after unilateral ACLR from blood drawn at rest and 3.5 h after 30 min of walking. An optoelectronic system and a force plate measured subjects' knee kinetics. Correlations were tested between inflammatory marker response and knee extension and knee adduction moments. FINDINGS: Changes in proinflammatory cytokines due to mechanical stimulus were correlated (R = 0.86) and showed substantial variation between subjects in both cytokines at 3.5 h post-walk. Knee loading correlated with 3.5-h changes in tumor necrosis factor-α concentration (Knee extension moment: R = -0.5, Knee adduction moment: R = -0.5) and Interleukin-1ß concentration (Knee extension moment: R = -0.44). However, no significant changes in concentrations were observed in tumor necrosis factor-α and Interleukin-1ß when comparing baseline and post walking stimulus conditions. INTERPRETATION: The significant associations between changes in serum proinflammatory markers following a mechanical stimulus and gait metrics in subjects at risk for developing Osteoarthritis underscore the importance of investigating the interaction between biomarkers and biomechanical factors in Osteoarthritis development.


Subject(s)
Anterior Cruciate Ligament Reconstruction , Cytokines , Knee Joint , Humans , Male , Female , Cytokines/blood , Adult , Knee Joint/physiopathology , Gait , Anterior Cruciate Ligament Injuries/surgery , Anterior Cruciate Ligament Injuries/physiopathology , Weight-Bearing , Interleukin-1beta/blood , Walking , Tumor Necrosis Factor-alpha/blood , Young Adult , Osteoarthritis, Knee/physiopathology , Osteoarthritis, Knee/blood , Osteoarthritis, Knee/surgery , Biomechanical Phenomena , Biomarkers/blood , Stress, Mechanical , Anterior Cruciate Ligament/surgery
6.
Sensors (Basel) ; 24(12)2024 Jun 13.
Article in English | MEDLINE | ID: mdl-38931598

ABSTRACT

Traditional motion analysis systems are impractical for widespread screening of non-contact anterior cruciate ligament (ACL) injury risk. The Kinect V2 has been identified as a portable and reliable alternative but was replaced by the Azure Kinect. We hypothesize that the Azure Kinect will assess drop vertical jump (DVJ) parameters associated with ACL injury risk with similar accuracy to its predecessor, the Kinect V2. Sixty-nine participants performed DVJs while being recorded by both the Azure Kinect and the Kinect V2 simultaneously. Our software analyzed the data to identify initial coronal, peak coronal, and peak sagittal knee angles. Agreement between the two systems was evaluated using the intraclass correlation coefficient (ICC). There was poor agreement between the Azure Kinect and the Kinect V2 for initial and peak coronal angles (ICC values ranging from 0.135 to 0.446), and moderate agreement for peak sagittal angles (ICC = 0.608, 0.655 for left and right knees, respectively). At this point in time, the Azure Kinect system is not a reliable successor to the Kinect V2 system for assessment of initial coronal, peak coronal, and peak sagittal angles during a DVJ, despite demonstrating superior tracking of continuous knee angles. Alternative motion analysis systems should be explored.


Subject(s)
Anterior Cruciate Ligament Injuries , Humans , Male , Female , Adult , Anterior Cruciate Ligament Injuries/physiopathology , Biomechanical Phenomena/physiology , Young Adult , Movement/physiology , Knee Joint/physiology , Range of Motion, Articular/physiology , Software
7.
Knee ; 48: 243-256, 2024 Jun.
Article in English | MEDLINE | ID: mdl-38781829

ABSTRACT

BACKGROUND: Anterior cruciate ligament reconstruction (ACLR) is a common orthopedic surgery procedure whose incidence has increased over the past few decades. Nevertheless, it is believed that neuromuscular control remains altered from the early stages after ACLR to later years. Therefore, the aim of this study was to systematically evaluate the magnitude of co-contraction during functional tasks in subjects with unilateral ACLR. METHODS: A systematic review design was followed. The search strategy was conducted in PubMed, Scopus, EBSCO, PEDro, Cochrane Library, and Web of Science databases from inception to March 2024. The inclusion criteria involved studies using electromyography (EMG) data to calculate muscle pair activation via the co-contraction index (CCI) in ACLR individuals during functional tasks. The Preferred Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were followed, and study quality was evaluated using National Institutes of Health (NIH) Study Quality Assessment Tools. RESULTS: The search strategy found a total of 792 studies, of which 15 were included in this systematic review after reviewing the eligibility criteria. The magnitude of co-contraction was assessed in a total of 433 ACLR individuals and 206 controls during functional tasks such as hop, drop-land, step-up/step-down, and gait. Overall, approximately 79.6% of individuals who had undergone ACLR exhibited increased levels of co-contraction magnitude in the ACLR limb, while 8.5% showed low co-contraction levels. CONCLUSIONS: The findings of the review suggest that, during functional tasks, most individuals who have undergone ACLR exhibit changes of co-contraction magnitude in the involved limb.


Subject(s)
Anterior Cruciate Ligament Reconstruction , Electromyography , Humans , Anterior Cruciate Ligament Injuries/surgery , Anterior Cruciate Ligament Injuries/physiopathology , Muscle Contraction/physiology , Muscle, Skeletal/physiopathology
8.
Knee ; 48: 226-233, 2024 Jun.
Article in English | MEDLINE | ID: mdl-38763073

ABSTRACT

BACKGROUND: Terminal extension lag (TEL) is common following anterior cruciate ligament reconstruction (ACLR). Clamshell exercises have been suggested as a potential intervention to address TEL, but limited research has been conducted in this area. OBJECTIVE: This study aimed to determine the effects of Clamshell exercises in terminal extension lag after anterior cruciate ligament reconstruction. METHODS: This randomized controlled trial included 40 participants with a history of ACLR between 1 and 3 years prior. Participants were randomly assigned to either the experimental group (Group A) or the control group (Group B). Group A received conventional exercises along with isolated hip strengthening rehabilitation, while Group B received conventional exercises without specific hip strengthening. The primary outcomes were pain levels (Numeric Pain Rating Scale), knee function (International Knee Documentation Committee scores, (IKDC)), range of motions (goniometer) and strength (sphygmomanometer). RESULTS: In between the group comparison shows that all outcome measures (NPRS, IKDC, Goniometer, Sphygmomanometer) show significant results (p < 0.05). Within-group comparisons (paired sample t-test) show that there was a significant difference (p < 0.05) in all outcome measures of both groups. CONCLUSION: The addition of Clamshell exercises to the rehabilitation program resulted in a significantly greater reduction in TEL compared to the control group. These findings suggest that Clamshell exercises were found to be an effective intervention for addressing TEL after ACLR.


Subject(s)
Anterior Cruciate Ligament Reconstruction , Exercise Therapy , Range of Motion, Articular , Humans , Anterior Cruciate Ligament Reconstruction/rehabilitation , Male , Female , Adult , Exercise Therapy/methods , Young Adult , Anterior Cruciate Ligament Injuries/surgery , Anterior Cruciate Ligament Injuries/rehabilitation , Anterior Cruciate Ligament Injuries/physiopathology , Knee Joint/surgery , Knee Joint/physiopathology
9.
Am J Sports Med ; 52(8): 1960-1969, 2024 Jul.
Article in English | MEDLINE | ID: mdl-38819001

ABSTRACT

BACKGROUND: Injuries to the deep medial collateral ligament (dMCL) and partial superficial MCL (psMCL) can cause anteromedial rotatory instability; however, the contribution of each these injuries in restraining anteromedial rotatory instability and the effect on the anterior cruciate ligament (ACL) load remain unknown. PURPOSE: To investigate the contributions of the different MCL structures in restraining tibiofemoral motion and to evaluate the load through the ACL after MCL injury, especially after combined dMCL/psMCL injury. STUDY DESIGN: Controlled laboratory study. METHODS: Sixteen fresh-frozen human cadaveric knees were tested using a 6 degrees of freedom robotic simulator. Tibiofemoral kinematic parameters were recorded at 0°, 30°, 60°, and 90° of knee flexion for the following measurements: 8-N·m valgus rotation, 4-N·m external tibial rotation (ER), 4-N·m internal tibial rotation, and a combined 89-N anterior tibial translation and 4-N·m ER for both anteromedial rotation (AMR) and anteromedial translation (AMT). The kinematic parameters of the 3 different MCL injuries (dMCL; dMCL/psMCL; dMCL/superficial MCL (sMCL)) were recorded and reapplied either in an ACL-deficient joint (load sharing) or before and after cutting the ACL (ACL load). The loads were calculated by applying the principle of superposition. RESULTS: The dMCL had the largest effect on reducing the force/torque during ER, AMR, and AMT in extension and the psMCL injury at 30° to 90° of knee flexion (P < .05). In a comparison of the load through the ACL when the MCL was intact, the ACL load increased by 46% and 127% after dMCL injury and combined dMCL/psMCL injury, respectively, at 30° of knee flexion during ER. In valgus rotation, a significant increase in ACL load was seen only at 90° of knee flexion. CONCLUSION: The psMCL injury made the largest contribution to the reduction of net force/torque during AMR/AMT at 30° to 90° of flexion. Concomitant dMCL/psMCL injury increased the ACL load, mainly during ER. CLINICAL RELEVANCE: If a surgical procedure is being considered to treat anteromedial rotatory instability, then the procedure should focus on restoring sMCL function, as injury to this structure causes a major loss of the knee joint's capacity to restrain AMR/AMT.


Subject(s)
Anterior Cruciate Ligament , Medial Collateral Ligament, Knee , Weight-Bearing , Humans , Medial Collateral Ligament, Knee/injuries , Medial Collateral Ligament, Knee/physiopathology , Biomechanical Phenomena , Weight-Bearing/physiology , Middle Aged , Anterior Cruciate Ligament/physiopathology , Anterior Cruciate Ligament/physiology , Male , Cadaver , Female , Joint Instability/physiopathology , Aged , Anterior Cruciate Ligament Injuries/physiopathology , Anterior Cruciate Ligament Injuries/surgery , Rotation , Knee Joint/physiology , Knee Joint/physiopathology , Knee Injuries/physiopathology , Adult , Range of Motion, Articular/physiology
10.
Motor Control ; 28(3): 341-361, 2024 Jul 01.
Article in English | MEDLINE | ID: mdl-38702047

ABSTRACT

The aim of this study was to examine the effect of attentional focus instructions on the biomechanical variables associated with the risk of anterior cruciate ligament injury of the knee joint during a drop landing task using a time series analysis. Ten female volleyball players (age: 20.4 ± 0.8 years, height: 169.7 ± 7.1 cm, mass: 57.6 ± 3.1 kg, experience: 6.3 ± 0.8 years) performed landings from a 50 cm height under three different attentional focus conditions: (1) external focus (focus on landing as soft as possible), (2) internal focus (focus on bending your knees when you land), and (3) control (no-focus instruction). Statistical parameter mapping in the sagittal plane during the crucial first 30% of landing time showed a significant effect of attentional focus instructions. Despite the similarity in landing performance across foci instructions, adopting an external focus instruction promoted reduced vertical ground reaction force and lower sagittal flexion moment during the first 30% of execution time compared to internal focus, suggesting reduced knee loading. Therefore, adopting an external focus of attention was suggested to reduce most biomechanical risk variables in the sagittal plane associated with anterior cruciate ligament injuries, compared to internal focus and control condition. No significant differences were found in the frontal and horizontal planes between the conditions during this crucial interval.


Subject(s)
Attention , Knee Joint , Volleyball , Humans , Female , Volleyball/physiology , Biomechanical Phenomena/physiology , Knee Joint/physiology , Young Adult , Attention/physiology , Anterior Cruciate Ligament Injuries/physiopathology
11.
J Sports Sci ; 42(7): 599-610, 2024 Apr.
Article in English | MEDLINE | ID: mdl-38734986

ABSTRACT

Unanticipated trunk perturbation is commonly observed when anterior cruciate ligament (ACL) injuries occur during direction-changing manoeuvres. This study aimed to quantify the effect of mid-flight medial-lateral external trunk perturbation directions/locations on ACL loading variables during sidestep cuttings. Thirty-two recreational athletes performed sidestep cuttings under combinations of three perturbation directions (no-perturbation, ipsilateral-perturbation, and contralateral-perturbation relative to the cutting leg) and two perturbation locations (upper-trunk versus lower-trunk). The pushing perturbation was created by customised devices releasing a slam ball to contact participants near maximum jump height prior to cutting. Perturbation generally resulted in greater peak vertical ground reaction force and slower cutting velocity. Upper-trunk contralateral perturbation showed the greatest lateral trunk bending away from the travel direction, greatest peak knee flexion and abduction angles, and greatest peak internal knee adduction moments compared to other conditions. Such increased ACL loading variables were likely due to the increased lateral trunk bending and whole-body horizontal velocity away from the cutting direction caused by the contralateral perturbation act at the upper trunk. The findings may help understand the mechanisms of indirect contact ACL injuries and develop effective cutting techniques for ACL injury prevention.


Subject(s)
Anterior Cruciate Ligament Injuries , Torso , Humans , Torso/physiology , Biomechanical Phenomena , Anterior Cruciate Ligament Injuries/physiopathology , Anterior Cruciate Ligament Injuries/prevention & control , Male , Young Adult , Female , Anterior Cruciate Ligament/physiology , Movement/physiology , Knee/physiology , Adult
12.
Orthop Surg ; 16(6): 1364-1373, 2024 Jun.
Article in English | MEDLINE | ID: mdl-38693612

ABSTRACT

OBJECTIVE: Early articular cartilage lesion (CL) is a vital sign in the onset of posttraumatic knee osteoarthritis (PTOA) in patients with anterior cruciate ligament deficiency (ACLD). Researchers have suggested that altered kinematics could accelerate CLs and, therefore, lead to the onset of PTOA. However, little is known about whether specific knee kinematics exist that lead to early CL in chronic ACLD knees. Level walking is the most frequent and relevant in vivo activity, which greatly impacts knee health. We hypothesized that the knee kinematics during level walking in chronic ACLD knees with early tibiofemoral CL would significantly differ from those of chronic ACLD knees without early tibiofemoral CL. METHODS: Thirty patients with a chronic ACLD history, including 18 subjects with CLs and 12 subjects without CLs, and 35 healthy control subjects were recruited for the study from July 2020 to August 2022. The knee kinematic data during level walking were collected using a three-dimensional motion analysis system. The kinematic differences between groups were compared using statistical parametric mapping with one dimension for One-Way ANOVA. The cartilage statuses of the ACLD knees were assessed via MRI examination. The CLs distribution of subjects was evaluated using a modified Noyes scale and analyzed by chi-square tests. RESULTS: ACLD knees with CLs had significantly greater posterior tibial translation (7.7-8.0mm, 12%-18% gait cycle GC, p = 0.014) compared to ACLD knees without CLs during level walking. ACLD knees with CLs had greater posterior tibial translation (4.6-5.5mm, 0%-23% GC, p < 0.001; 5.8-8.0mm, 86%-100% GC, p < 0.001) than healthy controls during level walking. In the group of ACLD knees with CLs, CL is mainly located in the back of the tibia plateau and front of load bearing area of the medial femoral condyle (p < 0.05). CONCLUSION: Chronic anterior cruciate ligament deficient knees with cartilage lesions have increased posterior tibial translation compared to anterior cruciate ligament deficient knees without cartilage lesions and healthy subjects. The posterior tibial translation may play an important role in knee cartilage degeneration in ACLD knees. The increased posterior tibial translation and cartilage lesion characteristics may improve our understanding of the role of knee kinematics in cartilage degeneration and could be a helpful potential reference for anterior cruciate ligament deficient therapy, such as physical training to improve abnormal kinematic behavior.


Subject(s)
Anterior Cruciate Ligament Injuries , Cartilage, Articular , Walking , Humans , Male , Female , Biomechanical Phenomena , Cartilage, Articular/physiopathology , Walking/physiology , Adult , Anterior Cruciate Ligament Injuries/physiopathology , Young Adult , Case-Control Studies , Chronic Disease , Tibia/physiopathology , Magnetic Resonance Imaging , Osteoarthritis, Knee/physiopathology
13.
Clin Sports Med ; 43(3): 501-512, 2024 Jul.
Article in English | MEDLINE | ID: mdl-38811124

ABSTRACT

Surgical intervention after anterior cruciate ligament (ACL) tears is typically required because of the limited healing capacity of the ACL. However, mechanical factors and the inflammatory response triggered by the injury and surgery can impact patient outcomes. This review explores key aspects of ACL injury and reconstruction biology, including the inflammatory response, limited spontaneous healing, secondary inflammation after reconstruction, and graft healing processes. Understanding these biologic mechanisms is crucial for developing new treatment strategies and enhancing patient well-being. By shedding light on these aspects, clinicians and researchers can work toward improving quality of life for individuals affected by ACL tears.


Subject(s)
Anterior Cruciate Ligament Injuries , Anterior Cruciate Ligament Reconstruction , Wound Healing , Humans , Anterior Cruciate Ligament Injuries/surgery , Anterior Cruciate Ligament Injuries/physiopathology , Wound Healing/physiology , Inflammation , Quality of Life
14.
J Biomech ; 170: 112150, 2024 Jun.
Article in English | MEDLINE | ID: mdl-38797082

ABSTRACT

Hip and knee biomechanics measured during a drop vertical jump (DVJ) can be used to assess patients undergoing rehabilitation after anterior cruciate ligament (ACL) reconstruction. To confidently interpret such data for use as outcome measures, additional information about reliability and validity is required. Therefore, the objective of this study was to estimate the test-retest reliability and longitudinal validity of selected lower limb biomechanics assessed during a DVJ in patients undergoing rehabilitation after ACL reconstruction. Biomechanical analysis of the DVJ in primary unilateral ACL reconstruction patients (22.3 ± 5.5y) were tested twice within 1 week at 6 months post-surgery (n = 46), and again at 12 months post-surgery (n = 36). Peak and initial contact knee angles and moments, hip impulse, vertical ground reaction forces (VGRF), isokinetic knee extension and flexion strength, and global ratings of change (GRC) were assessed. Reliability was evaluated based on the 6-month post-surgery data using intraclass correlation coefficients (ICC2,1), standard errors of measurement and minimum detectable change. Longitudinal validity was evaluated by assessing change from 6 to 12 months, using standardized response means (SRM), and by assessing the correlation (Pearson's r) of change in landing biomechanics with change in strength, and GRC. ICCs ranged from 0.58 to 0.90 for peak knee abduction and flexion moments, 0.44-0.85 for knee flexion and abduction angles, 0.82-0.93 for VGRFs, and 0.42-0.65 for hip impulse. SRMs and correlations of change ranged from 0.00 to 0.50. Reliability and longitudinal validity of DVJ measures varied, ranging from poor-to-excellent; the present results assist in their interpretation when assessed during rehabilitation after ACL reconstruction.


Subject(s)
Anterior Cruciate Ligament Reconstruction , Humans , Anterior Cruciate Ligament Reconstruction/rehabilitation , Male , Female , Biomechanical Phenomena , Adult , Reproducibility of Results , Knee Joint/physiopathology , Knee Joint/physiology , Knee Joint/surgery , Young Adult , Longitudinal Studies , Adolescent , Anterior Cruciate Ligament Injuries/surgery , Anterior Cruciate Ligament Injuries/physiopathology , Anterior Cruciate Ligament Injuries/rehabilitation
15.
BMC Musculoskelet Disord ; 25(1): 382, 2024 May 14.
Article in English | MEDLINE | ID: mdl-38745166

ABSTRACT

BACKGROUND: An isokinetic moment curve (IMC) pattern-damaged structure prediction model may be of considerable value in assisting the diagnosis of knee injuries in clinical scenarios. This study aimed to explore the association between irregular IMC patterns and specific structural damages in the knee, including anterior cruciate ligament (ACL) rupture, meniscus (MS) injury, and patellofemoral joint (PFJ) lesions, and to develop an IMC pattern-damaged structure prediction model. METHODS: A total of 94 subjects were enrolled in this study and underwent isokinetic testing of the knee joint (5 consecutive flexion-extension movements within the range of motion of 90°-10°, 60°/s). Qualitative analysis of the IMCs for all subjects was completed by two blinded examiners. A multinomial logistic regression analysis was used to investigate whether a specific abnormal curve pattern was associated with specific knee structural injuries and to test the predictive effectiveness of IMC patterns for specific structural damage in the knee. RESULTS: The results of the multinomial logistic regression revealed a significant association between the irregular IMC patterns of the knee extensors and specific structural damages ("Valley" - ACL, PFJ, and ACL + MS, "Drop" - ACL, and ACL + MS, "Shaking" - ACL, MS, PFJ, and ACL + MS). The accuracy and Macro-averaged F1 score of the predicting model were 56.1% and 0.426, respectively. CONCLUSION: The associations between irregular IMC patterns and specific knee structural injuries were identified. However, the accuracy and Macro-averaged F1 score of the established predictive model indicated its relatively low predictive efficacy. For the development of a more accurate predictive model, it may be essential to incorporate angle-specific and/or speed-specific analyses of qualitative and quantitative data in isokinetic testing. Furthermore, the utilization of artificial intelligence image recognition technology may prove beneficial for analyzing large datasets in the future.


Subject(s)
Anterior Cruciate Ligament Injuries , Knee Joint , Range of Motion, Articular , Humans , Male , Female , Adult , Range of Motion, Articular/physiology , Knee Joint/physiopathology , Anterior Cruciate Ligament Injuries/physiopathology , Young Adult , Biomechanical Phenomena/physiology , Knee Injuries/physiopathology , Predictive Value of Tests , Tibial Meniscus Injuries/physiopathology , Patellofemoral Joint/physiopathology , Patellofemoral Joint/injuries , Middle Aged
16.
J Bodyw Mov Ther ; 38: 168-174, 2024 Apr.
Article in English | MEDLINE | ID: mdl-38763558

ABSTRACT

INTRODUCTION: After anterior cruciate ligament (ACL) reconstruction, determining readiness to return to participation is challenging. The understanding of which neuromuscular performance parameters are associated with limb symmetry and self-reported symptoms may be useful to improve monitoring the rehabilitation towards adequate decision-making to return. OBJECTIVES: To compare the ACL-operated and injury-free lower limbs regarding functional performance; and to investigate whether lower limb strength and functional performance are associated with self-reported symptoms and functional lower limb symmetry. METHOD: Thirty-four participants were included. Functional performance was assessed by using the Y-Balance test, Single-leg Hop, and Functional Movement Screen. An isokinetic dynamometer was used to evaluate the strength levels in open and closed kinetic chains. The functional lower limb symmetry was calculated considering the single-leg hop test results for each lower limb. RESULTS: There were no differences in dynamic balance (Y-Balance) between the operated and injury-free limbs. The operated limb presented a worst performance in the single-leg hop. Self-reported symptoms prevalence and lower limb symmetry were associated with knee extension strength and functional performance (Y-Balance). CONCLUSION: Individuals submitted to ACL-reconstruction presented worse functional performance in the operated limb compared to the injury-free limb. Both knee strength and dynamic balance were associated with limb symmetry and self-reported symptoms.


Subject(s)
Anterior Cruciate Ligament Injuries , Anterior Cruciate Ligament Reconstruction , Lower Extremity , Muscle Strength , Self Report , Humans , Anterior Cruciate Ligament Reconstruction/rehabilitation , Male , Cross-Sectional Studies , Female , Adult , Brazil , Muscle Strength/physiology , Young Adult , Lower Extremity/physiopathology , Anterior Cruciate Ligament Injuries/physiopathology , Anterior Cruciate Ligament Injuries/surgery , Postural Balance/physiology
18.
J Orthop Surg Res ; 19(1): 280, 2024 May 06.
Article in English | MEDLINE | ID: mdl-38711149

ABSTRACT

INTRODUCTION: The escalating incidence of anterior cruciate ligament (ACL) injuries, particularly among adolescents, is a pressing concern. The study of ACL biomechanics in this demographic presents challenges due to the scarcity of cadaveric specimens. This research endeavors to validate the adolescent porcine stifle joint as a fitting model for ACL studies. METHODS: We conducted experiments on 30 fresh porcine stifle knee joints. (Breed: Yorkshire, Weight: avg 90 lbs, Age Range: 2-4 months). They were stored at - 22 °C and a subsequent 24-h thaw at room temperature before being prepared for the experiment. These joints were randomly assigned to three groups. The first group served as a control and underwent only the load-to-failure test. The remaining two groups were subjected to 100 cycles, with forces of 300N and 520N, respectively. The load values of 300N and 520N correspond to three and five times the body weight (BW) of our juvenile porcine, respectively. RESULT: The 520N force demonstrated a higher strain than the 300N, indicating a direct correlation between ACL strain and augmented loads. A significant difference in load-to-failure (p = 0.014) was observed between non-cyclically loaded ACLs and those subjected to 100 cycles at 520N. Three of the ten samples in the 520N group failed before completing 100 cycles. The ruptured ACLs from these tests closely resembled adolescent ACL injuries in detachment patterns. ACL stiffness was also measured post-cyclical loading by applying force and pulling the ACL at a rate of 1 mm per sec. Moreover, ACL stiffness measurements decreased from 152.46 N/mm in the control group to 129.42 N/mm after 100 cycles at 300N and a more significant drop to 86.90 N/mm after 100 cycles at 520N. A one-way analysis of variance (ANOVA) and t-test were chosen for statistical analysis. CONCLUSIONS: The porcine stifle joint is an appropriate model for understanding ACL biomechanics in the skeletally immature demographic. The results emphasize the ligament's susceptibility to injury under high-impact loads pertinent to sports activities. The study advocates for further research into different loading scenarios and the protective role of muscle co-activation in ACL injury prevention.


Subject(s)
Anterior Cruciate Ligament , Stifle , Weight-Bearing , Animals , Swine , Anterior Cruciate Ligament/physiology , Anterior Cruciate Ligament/physiopathology , Stifle/physiology , Stifle/physiopathology , Weight-Bearing/physiology , Biomechanical Phenomena , Anterior Cruciate Ligament Injuries/physiopathology , Stress, Mechanical , In Vitro Techniques
19.
Sci Rep ; 14(1): 11922, 2024 05 24.
Article in English | MEDLINE | ID: mdl-38789542

ABSTRACT

Stress concentration on the Anterior Cruciate Ligament Reconstruction (ACLr) for femoral drillings is crucial to understanding failures. Therefore, we described the graft stress for transtibial (TT), the anteromedial portal (AM), and hybrid transtibial (HTT) techniques during the anterior tibial translation and medial knee rotation in a finite element model. A healthy participant with a non-medical record of Anterior Cruciate Ligament rupture with regular sports practice underwent finite element analysis. We modeled TT, HTT, AM drillings, and the ACLr as hyperelastic isotropic material. The maximum Von Mises principal stresses and distributions were obtained from anterior tibial translation and medial rotation. During the anterior tibia translation, the HTT, TT, and AM drilling were 31.5 MPa, 34.6 Mpa, and 35.0 MPa, respectively. During the medial knee rotation, the AM, TT, and HTT drilling were 17.3 MPa, 20.3 Mpa, and 21.6 MPa, respectively. The stress was concentrated at the lateral aspect of ACLr,near the femoral tunnel for all techniques independent of the knee movement. Meanwhile, the AM tunnel concentrates the stress at the medial aspect of the ACLr body under medial rotation. The HTT better constrains the anterior tibia translation than AM and TT drillings, while AM does for medial knee rotation.


Subject(s)
Anterior Cruciate Ligament Reconstruction , Femur , Finite Element Analysis , Stress, Mechanical , Tibia , Humans , Anterior Cruciate Ligament Reconstruction/methods , Femur/surgery , Tibia/surgery , Rotation , Male , Biomechanical Phenomena , Adult , Knee Joint/surgery , Knee Joint/physiopathology , Anterior Cruciate Ligament Injuries/surgery , Anterior Cruciate Ligament Injuries/physiopathology , Anterior Cruciate Ligament/surgery
20.
Sci Rep ; 14(1): 11440, 2024 05 20.
Article in English | MEDLINE | ID: mdl-38769088

ABSTRACT

This study aimed to compare functional outcomes sequentially up to 1 year after combined anterior cruciate ligament reconstruction (ACLR) and anterolateral ligament reconstruction (ALLR) and isolated ACLR. Fifty patients who underwent ACLR with versus without ALLR were analyzed at four different time points (preoperatively and 3, 6, and 12 months postoperatively). For the functional outcomes, muscle strength and acceleration time (AT) were measured using an isokinetic dynamometer. Proprioception was evaluated using joint position sense and dynamic postural stability. Patient-reported outcomes were measured using the Tampa Scale for Kinesiophobia (TSK-11) scores. Functional performance was assessed using single-leg hop distance (SLHD) and Limb Symmetry Index. In the operated knees, quadriceps (at 6 months postoperatively, p = 0.003) and hamstring (at 6 and 12 months postoperatively, p < 0.001) strength were significantly higher in the combined ACLR and ALLR group than the isolated ACLR group. The TSK-11 (at 6 and 12 months postoperatively, p < 0.001) was significantly lower in the combined ACLR and ALLR group than the isolated ACLR group. SLHD was significantly higher in the combined ACLR and ALLR group than the isolated ACLR group (at 6 months, p = 0.022 and at 12 months, p = 0.024). The addition of ALLR to primary ACLR yielded better muscle performance, fear of movement, and functional performance than isolated ACLR.


Subject(s)
Anterior Cruciate Ligament Reconstruction , Muscle Strength , Recovery of Function , Humans , Anterior Cruciate Ligament Reconstruction/methods , Male , Female , Adult , Muscle Strength/physiology , Anterior Cruciate Ligament Injuries/surgery , Anterior Cruciate Ligament Injuries/physiopathology , Young Adult , Treatment Outcome , Anterior Cruciate Ligament/surgery , Anterior Cruciate Ligament/physiopathology , Proprioception/physiology , Knee Joint/surgery , Knee Joint/physiopathology , Patient Reported Outcome Measures , Adolescent
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