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1.
J Environ Sci (China) ; 150: 177-187, 2025 Apr.
Article in English | MEDLINE | ID: mdl-39306394

ABSTRACT

Evaluating the pressure of atmospheric pollutant emissions on the atmospheric environment is crucial for effective pollution control and emission reduction policies. This study introduces a novel Atmospheric Environmental Pressure Index (AEPI) and employs a dynamic comprehensive method to evaluate China's Atmospheric Environmental Pressure (AEP) across 31 provinces from 2008 to 2017. The drivers of AEP were analyzed using a spatial panel data model, uncovering the integral role of pollution reduction policies, particularly the Air Pollution Prevention and Control Action Plan, which led to a 25% reduction in AEP during its enforcement. Our findings reveal significant spatial disparities in AEP, with higher levels in the Beijing-Tianjin-Hebei and Yangtze River Delta regions. The regression analysis identifies economic development, industrial structure, energy efficiency, environmental regulations, and urbanization as key influencing factors, though their impacts vary across different regions, suggesting the need for region-specific pollution control policies. Furthermore, the shift in the AEP gravity center from 2008 to 2017 indicated a southeastward movement, suggesting the necessity to focus air pollution control efforts on the southeast provinces. In conclusion, the AEPI developed in this study enables comparative analysis of AEP across different regions and facilitates the monitoring of long-term trends, which is valuable in guiding regional air pollution control in China.


Subject(s)
Air Pollutants , Air Pollution , Environmental Monitoring , China , Air Pollution/statistics & numerical data , Air Pollution/prevention & control , Environmental Monitoring/methods , Air Pollutants/analysis , Atmospheric Pressure , Urbanization/trends
2.
Sci Rep ; 14(1): 21426, 2024 09 13.
Article in English | MEDLINE | ID: mdl-39271708

ABSTRACT

Referring to the intestinal ischemic injury caused by sudden interruption of the blood supply, acute mesenteric ischemia (AMI) is a highly fatal emergency with mortality rates varying from 58 to 80%. The aim of this study was to explore the effect of temperature on AMI admission. This was a retrospective, multicentric study. The medical records of 1477 patients with verified AMI who were consecutively admitted to 3 hospitals anytime between January 2010 and December 2020 were included in the study. Distributed lag non-linear model was applied, the model was adjusted for temperature, atmospheric pressure, relative humidity, year, holiday, day of the week, time and seasonality. AMI exhibited obvious sex preference, AMI patients tended to be male (M/F ratio = 2.3:1) and in their late 50 s. Hospital admissions of acute mesenteric arterial thromboembolism (AMAT) increased significantly with high temperatures on day of exposure and lag 0-14 day. The effect curve of daily average temperature on acute mesenteric venous thromboembolism (AMVT) admission was J-shaped, and the duration of cold effect was longer, while the duration of heat effect was shorter. An increase in hospital admissions of AMVT was found above 20 °C at lag 0-30. For the first time, our study indicated that temperature is significantly associated with the risk of AMI. Although it is not possible to always avoid exposure to extreme temperatures, one should be aware of dramatic temperature fluctuations and take appropriate precautions.


Subject(s)
Atmospheric Pressure , Humidity , Mesenteric Ischemia , Temperature , Humans , Male , Female , Aged , Retrospective Studies , Middle Aged , Hospitalization , Acute Disease , Patient Admission , Seasons , Aged, 80 and over
3.
Diving Hyperb Med ; 54(3): 212-216, 2024 Sep 30.
Article in English | MEDLINE | ID: mdl-39288926

ABSTRACT

Introduction: The stability of a new hyperbaric ventilator (Shangrila590, Beijing Aeonmed Company, Beijing, China) at different clinically relevant pressures in a hyperbaric chamber during pressure-controlled ventilation (PCV) was investigated. Methods: The ventilator was connected to a test lung in the multiplace hyperbaric chamber. The inspiratory pressure (PI) of the ventilator was set to 1.0, 1.5, 2.0, 2.5 and 3.0 kPa (approximately 10, 15, 20, 25 and 30 cmH2O). The compliance and resistance of the test lung were set to 200 mL·kPa⁻¹ and 2 kPa·L⁻¹·s⁻¹, respectively. Experiments were conducted at 101, 203 and 284 kPa ambient pressure (1.0, 2.0 and 2.8 atmospheres absolute respectively). At each of the 5 PI values, the tidal volume (VT), peak inspiratory pressure (Ppeak) and peak inspiratory flow (Fpeak) displayed by the ventilator and the test lung were recorded for 20 cycles. Test lung data were considered the actual ventilation values. The ventilation data were compared among the three groups to evaluate the stability of the ventilator. Results: At every PI, the Ppeak detected by the ventilator decreased slightly with increasing ambient pressure. The Fpeak values measured by the test lung decreased substantially as the ambient pressure increased. Nevertheless, the reduction in VT at 284 kPa and PI 30 cmH2O (compared to performance at 101 kPa) was comparatively small (approximately 60 ml). Conclusions: In PCV mode this ventilator provided relatively stable VT across clinically relevant PI values to ambient pressures as high as 284 kPa. However, because Fpeak decreases at higher ambient pressure, some user adjustment might be necessary for precise VT maintenance during clinical use at higher PIs and ambient pressures.


Subject(s)
Hyperbaric Oxygenation , Tidal Volume , Ventilators, Mechanical , Hyperbaric Oxygenation/methods , Tidal Volume/physiology , Lung Compliance/physiology , Equipment Design , Humans , Atmosphere Exposure Chambers , Pressure , Maximal Respiratory Pressures , Atmospheric Pressure , Positive-Pressure Respiration/methods , Positive-Pressure Respiration/instrumentation , Respiration, Artificial/instrumentation , Respiration, Artificial/methods
4.
J Appl Microbiol ; 135(9)2024 Sep 02.
Article in English | MEDLINE | ID: mdl-39264067

ABSTRACT

AIMS: This study aims to assess the potential bacterial inactivation pathway triggered by argon (Ar) cold atmospheric pressure plasma jet (CAPJ) discharge using spectroscopic and imaging techniques. METHODS AND RESULTS: Electrical and reactive species of the Ar CAPJ discharge was characterized. The chemical composition and morphology of bacteria pre- and post-CAPJ exposure were assessed using Fourier transform infrared (FTIR), Raman micro-spectroscopy, and transmission electron microscopy (TEM). A greater than 6 log reduction of Escherichia coli and Staphylococcus aureus was achieved within 60 and 120 s of CAPJ exposure, respectively. Extremely low D-values (<20 s) were recorded for both the isolates. The alterations in the FTIR spectra and Raman micro-spectra signals of post-CAPJ exposed bacteria revealed the degree of destruction at the molecular level, such as lipid peroxidation, protein oxidation, bond breakages, etc. Further, TEM images of exposed bacteria indicated the incurred damages on cell morphology by CAPJ reactive species. Also, the inactivation process varied for both isolates, as evidenced by the correlation between the inactivation curve and FTIR spectra. It was observed that the identified gas-phase reactive species, such as Ar I, O I, OH•, NO+, OH+, NO2-, NO3-, etc. played a significant role in bacterial inactivation. CONCLUSIONS: This study clearly demonstrated the effect of CAPJ exposure on bacterial cell morphology and molecular composition, illuminating potential bacterial inactivation mechanisms.


Subject(s)
Argon , Atmospheric Pressure , Escherichia coli , Plasma Gases , Staphylococcus aureus , Argon/pharmacology , Plasma Gases/pharmacology , Escherichia coli/drug effects , Spectroscopy, Fourier Transform Infrared , Staphylococcus aureus/drug effects , Staphylococcus aureus/physiology , Microscopy, Electron, Transmission , Spectrum Analysis, Raman , Microbial Viability
5.
J Phys Chem A ; 128(34): 7208-7213, 2024 Aug 29.
Article in English | MEDLINE | ID: mdl-39141611

ABSTRACT

The hydrogen/deuterium (H/D) exchange rate is an optimal measure for studying the structures and dynamics of hydrogen bonding systems, as it reflects the molecular contact environment and the strength of the hydrogen bonds. A method for rapid measurement of the H/D exchange reaction rates is required to examine the intermolecular environments of molecules in solutions. We developed a droplet collision atmospheric pressure infrared laser ablation mass spectrometry technique for this purpose. We obtained the H/D exchange reaction rate of cytochrome c in a methanol/H2O·D2O solution. We revealed that the first hydration shell of the cytochrome c molecule hinders the penetration of D2O to the surface of the molecule from the rates, which provides a novel method to investigate solution structures by a mass-spectrometric method. The droplet-collision mass spectrometry method developed in the present study can be extended to research on the molecular interactions in solutions, such as the mutual interactions of protein molecules, which are of importance in living cells.


Subject(s)
Cytochromes c , Mass Spectrometry , Cytochromes c/chemistry , Cytochromes c/metabolism , Mass Spectrometry/methods , Atmospheric Pressure , Deuterium Exchange Measurement/methods , Lasers , Deuterium/chemistry , Deuterium Oxide/chemistry , Methanol/chemistry
6.
J Hazard Mater ; 479: 135640, 2024 Nov 05.
Article in English | MEDLINE | ID: mdl-39208626

ABSTRACT

Airborne allergens, especially those originating from various types of pollen, significantly compromise the health and well-being of individuals on a global scale. Here, cold atmospheric pressure plasma (CAP) created in ambient air was used to treat highly allergenic and invasive Ambrosia artemisiifolia pollen. Immunoassays were used to evaluate the impact of CAP on the principal A. artemisiifolia allergen Amb a 1, demonstrating that > 90 % reduction in antigenicity could be achieved. Chemical analyses using Fourier Transform infrared revealed that CAP induced significant alterations to proteins on the surface of pollen grains, resulting in a 43 % increase in the amide I peak area and a 57 % increase in the amide II peak area. These findings were corroborated by Raman and X-ray photoelectron spectroscopy, which indicated that the protein modifications induced by CAP were due to carbonylation and nitration/nitrosylation processes. Beyond protein transformations, CAP also induced notable oxidation and modification of lipid-like compounds, polysaccharides and sporopollenin. Evident transformations at the chemical level translated into morphological changes at the grain surface, manifesting as increased roughness via significant outer-layer etching. These findings underscore the potential of CAP technology as a viable approach for mitigating against the allergenicity of pollen, providing a deeper understanding into the underlying chemical mechanisms.


Subject(s)
Ambrosia , Antigens, Plant , Plasma Gases , Plasma Gases/chemistry , Ambrosia/immunology , Ambrosia/chemistry , Antigens, Plant/immunology , Antigens, Plant/chemistry , Allergens/immunology , Pollen/immunology , Pollen/chemistry , Atmospheric Pressure , Plant Proteins/immunology , Plant Proteins/chemistry , Plant Extracts
7.
J Exp Biol ; 227(17)2024 Sep 01.
Article in English | MEDLINE | ID: mdl-39155696

ABSTRACT

Barometric pressure is an environmental factor involved in the modulation of a variety of activities in insects. Generally, a drop in barometric pressure precedes the arrival of weather conditions that can affect insect activities and life expectancy. We simulated different scenarios of pressure drop in a modified hermetic chamber and studied their influence on the host-seeking behaviour of the larvae of the robber fly Mallophora ruficauda using air stationary olfactometers. In addition, we studied whether larval density modulates orientation to the host under the same scenarios of pressure drop. We found that motivation to search for hosts is affected by the same slope of pressure drop in both low- and high-density larvae. However, larval density modulates the onset of the responses to pressure decrease, as low-density larvae stop searching for hosts more quickly than high-density larvae. This result reflects an avoidance strategy according to which low-density larvae would have a reduced host range and higher risk of mortality and fewer chances to find a suitable host under adverse pressure conditions. Low-density larvae, known to prefer healthy hosts, do not search for parasitized hosts under normal pressure conditions nor under a range of pressure drops, strongly suggesting that host selectivity is not modulated by barometric pressure. This study paves the way to a better understanding of the changes in crucial insect behaviours induced by weather conditions, and provides more knowledge about the risk factors likely to affect insect survival in the context of foraging ecology.


Subject(s)
Diptera , Larva , Animals , Larva/physiology , Larva/growth & development , Diptera/physiology , Atmospheric Pressure , Population Density , Host-Parasite Interactions , Feeding Behavior/physiology
8.
BMC Res Notes ; 17(1): 221, 2024 Aug 09.
Article in English | MEDLINE | ID: mdl-39123190

ABSTRACT

OBJECTIVE: This study delves into the impact of urban meteorological elements-specifically, air temperature, relative humidity, and atmospheric pressure-on water consumption in Kamyaran city. Data on urban water consumption, temperature (in Celsius), air pressure (in hectopascals), and relative humidity (in percent) were used for the statistical period 2017-2023. Various models, including the correlation coefficient, generalized additive models (GAM), generalized linear models (GLM), and support vector machines (SVM), were employed to scrutinize the data. RESULTS: Water consumption increases due to the influence of relative humidity and air pressure when the temperature variable is controlled. Under specific air temperature conditions, elevated air pressure coupled with high relative humidity intensifies the response of water consumption to variations in these elements. Water consumption exhibits heightened sensitivity to high relative humidity and air pressure compared to low levels of these factors. During winter, when a western low-pressure air mass arrives and disrupts normal conditions, causing a decrease in pressure and temperature, urban water consumption also diminishes. The output from the models employed in this study holds significance for enhancing the prediction and management of water resource consumption.


Subject(s)
Cities , Humidity , Machine Learning , Temperature , Humans , Meteorological Concepts , Atmospheric Pressure , Seasons , Water Supply , Water
9.
Undersea Hyperb Med ; 51(2): 115-127, 2024.
Article in English | MEDLINE | ID: mdl-38985148

ABSTRACT

For over five decades, many experimental and clinical studies have shown predominantly positive but controversial results on the efficacy of hyperbaric oxygen (HBO2) therapy in burns. The study aimed to define a common denominator or constellations, respectively, linked to the effects of HBO2 in burns with a special focus on dosage parameters. Based on original work since 1965, species, number of individuals, type of study, percentage of total body surface area (TBSA), region, depth of burn, causative agent, interval between burn and first HBO2 session, pressure, duration of individual session, number of HBO2 sessions per day, cumulative number of HBO2 sessions and type of chamber were assessed. Out of 47 publications included, 32 were animal trials, four were trials in human volunteers, and 11 were clinical studies. They contained 94 experiments whose features were processed for statistical evaluation. 64 (67.4%) showed a positive outcome, 16 (17.9%) an ambiguous one, and 14 (14.7%) a negative outcome. The only factor independently influencing the results was pressure with ATA (atmospheres absolute) lower than 3 ATA being significantly associated with better outcomes (p=0.0005). There is a dire need for well-designed clinical studies in burn centers equipped with hyperbaric facilities to establish dedicated treatment protocols.


Subject(s)
Atmospheric Pressure , Burns , Hyperbaric Oxygenation , Hyperbaric Oxygenation/methods , Burns/therapy , Humans , Animals , Treatment Outcome , Clinical Trials as Topic
10.
Undersea Hyperb Med ; 51(2): 159-171, 2024.
Article in English | MEDLINE | ID: mdl-38985152

ABSTRACT

Work in compressed air and diving are both occupational activities that have been around since the mid-19th century, and those undertaking their work under elevated pressure. Meeting the demand to go to "higher pressure for longer" in tunneling has lagged in diving, but both activities have found it necessary to adopt mixed gas breathing and saturation exposure techniques. This paper explains how work in hyperbaric conditions at high pressure is undertaken in tunneling and is illustrated by the hyperbaric activity likely to be involved in constructing a large-diameter road tunnel below a body of water such as an estuary. It also explores the practical differences between work in compressed air and diving.


Subject(s)
Diving , Hyperbaric Oxygenation , Diving/physiology , Humans , Hyperbaric Oxygenation/methods , Compressed Air , Atmospheric Pressure
11.
Anal Chem ; 96(32): 13326-13334, 2024 Aug 13.
Article in English | MEDLINE | ID: mdl-39077860

ABSTRACT

The laser ablation remote atmospheric pressure photoionization/chemical ionization (LARAPPI/CI) platform coupled to an ultrahigh resolution quadrupole-time-of-flight (QToF) mass spectrometer was developed and employed for the first direct three-dimensional (3D) mass spectrometry imaging (MSI) of metabolites in human and plant tissues. Our solution for 3D MSI does not require sample modification or cutting into thin slices. Ablation characteristics of an optical system based on a diffraction optical element are studied and used for voxel stacking to directly remove layers of tissues. Agar gel, red radish, kiwi, human kidney cancer, and normal tissue samples were used for the tests of this new system. The 2D and 3D ion images vividly illustrate differences in the abundances of selected metabolites between cancerous and noncancerous regions of the kidney tissue and also between different parts of plant tissues. The LARAPPI/CI MSI setup is also the first example of the successful use of combined dopant-assisted atmospheric pressure photoionization (DA-APPI) and atmospheric pressure chemical ionization (APCI) ion source for mass spectrometry imaging.


Subject(s)
Atmospheric Pressure , Humans , Mass Spectrometry/methods , Lasers , Imaging, Three-Dimensional , Kidney Neoplasms , Raphanus/chemistry
12.
Sci Rep ; 14(1): 17067, 2024 07 24.
Article in English | MEDLINE | ID: mdl-39048618

ABSTRACT

Breath analysis is an area of significant interest in medical research as it allows for non-invasive sampling with exceptional potential for disease monitoring and diagnosis. Volatile organic compounds (VOCs) found in breath can offer critical insight into a person's lifestyle and/or disease/health state. To this end, the development of a rapid, sensitive, cost-effective and potentially portable method for the detection of key compounds in breath would mark a significant advancement. Herein, we have designed, built and tested a novel reagent-less atmospheric pressure photoionisation (APPI) source, coupled with mass spectrometry (MS), utilising a bespoke bias electrode within a custom 3D printed sampling chamber for direct analysis of VOCs. Optimal APPI-MS conditions were identified, including bias voltage, cone voltage and vaporisation temperature. Calibration curves were produced for ethanol, acetone, 2-butanone, ethyl acetate and eucalyptol, yielding R2 > 0.99 and limits of detection < 10 pg. As a pre-clinical proof of concept, this method was applied to bacterial headspace samples of Escherichia coli (EC), Pseudomonas aeruginosa (PSA) and Staphylococcus aureus (SA) collected in 1 L Tedlar bags. In particular, PSA and SA are commonly associated with lung infection in cystic fibrosis patients. The headspace samples were classified using principal component analysis with 86.9% of the total variance across the first three components and yielding 100% classification in a blind-sample study. All experiments conducted with the novel APPI arrangement were carried out directly in real-time with low-resolution MS, which opens up exciting possibilities in the future for on-site (e.g., in the clinic) analysis with a portable system.


Subject(s)
Atmospheric Pressure , Cystic Fibrosis , Mass Spectrometry , Pseudomonas aeruginosa , Volatile Organic Compounds , Cystic Fibrosis/microbiology , Humans , Volatile Organic Compounds/analysis , Pseudomonas aeruginosa/isolation & purification , Mass Spectrometry/methods , Breath Tests/methods , Escherichia coli/isolation & purification , Staphylococcus aureus/isolation & purification
13.
BMC Res Notes ; 17(1): 203, 2024 Jul 23.
Article in English | MEDLINE | ID: mdl-39044304

ABSTRACT

PURPOSE: The prevalence of migraine headache is higher in women. Low barometric pressure is a factor in headache triggering, but sex-related differences have not been identified. The purpose of this study was to examine sex-related differences in headache triggered by low barometric pressure. METHODS: Study subjects aged 20-49 years were randomly selected from a research company's (Macromill, Inc.) web panel. Those with chronic migraine or tension-type headache invited to complete a web-based self-administered questionnaire. Logistic regression analysis was performed with the objective variable as the Headache Impact Test-6 (HIT-6) high scores (56 or more) or headache triggered by low barometric pressure. RESULTS: Participants were 332 women and 337 men in the headache population. HIT-6 high scores were associated with age at headache occurrence 20 years or younger (OR: odds ratio 1.85, 95% CI: confidence interval 1.15-2.99, p = 0.012) and headache triggered by low barometric pressure (OR 2.11, 95%CI 1.51-2.94, p < 0.001). Headache triggered by low barometric pressure was significantly associated with women (OR 2.92, 95%CI 2.12-4.02, p < 0.001). CONCLUSIONS: Headache triggered by low barometric pressure were related to sex-related differences. It was suggested that a sex-specific treatment approach for headache triggering is needed.


Subject(s)
Migraine Disorders , Humans , Female , Male , Middle Aged , Adult , Japan/epidemiology , Migraine Disorders/epidemiology , Migraine Disorders/physiopathology , Young Adult , Headache/epidemiology , Headache/physiopathology , Surveys and Questionnaires , Sex Factors , Atmospheric Pressure , Tension-Type Headache/epidemiology , Tension-Type Headache/physiopathology , Sex Characteristics , Logistic Models
14.
Diving Hyperb Med ; 54(2): 110-119, 2024 Jun 30.
Article in English | MEDLINE | ID: mdl-38870953

ABSTRACT

Introduction: Inhalation of high concentrations of carbon dioxide (CO2) at atmospheric pressure can be toxic with dose-dependent effects on the cardiorespiratory system or the central nervous system. Exposure to both hyperbaric and hypobaric environments can result in decompression sickness (DCS). The effects of CO2 on DCS are not well documented with conflicting results. The objective was to review the literature to clarify the effects of CO2 inhalation on DCS in the context of hypobaric or hyperbaric exposure. Methods: The systematic review included experimental animal and human studies in hyper- and hypobaric conditions evaluating the effects of CO2 on bubble formation, denitrogenation or the occurrence of DCS. The search was based on MEDLINE and PubMed articles with no language or date restrictions and also included articles from the underwater and aviation medicine literature. Results: Out of 43 articles, only 11 articles were retained and classified according to the criteria of hypo- or hyperbaric exposure, taking into account the duration of CO2 inhalation in relation to exposure and distinguishing experimental work from studies conducted in humans. Conclusions: Before or during a stay in hypobaric conditions, exposure to high concentrations of CO2 favors bubble formation and the occurrence of DCS. In hyperbaric conditions, high CO2 concentrations increase the occurrence of DCS when exposure occurs during the bottom phase at maximum pressure, whereas beneficial effects are observed when exposure occurs during decompression. These opposite effects depending on the timing of exposure could be related to 1) the physical properties of CO2, a highly diffusible gas that can influence bubble formation, 2) vasomotor effects (vasodilation), and 3) anti-inflammatory effects (kinase-nuclear factor and heme oxygenase-1 pathways). The use of O2-CO2 breathing mixtures on the surface after diving may be an avenue worth exploring to prevent DCS.


Subject(s)
Carbon Dioxide , Decompression Sickness , Animals , Humans , Atmospheric Pressure , Diving/adverse effects , Diving/physiology
15.
J Biotechnol ; 392: 103-108, 2024 Sep 10.
Article in English | MEDLINE | ID: mdl-38944385

ABSTRACT

Here we report that non-thermal atmospheric-pressure plasma exposure can improve Brassica juncea (leaf mustard) seed germination rate from 50 % to 98 %. The commercially relevant germination rate was achieved by plasma exposure for only 10 minutes and the effect sustains at least for one month under an appropriate storage condition. Improved germination by plasma exposure was also observed for Brassica rapa subsp. pekinensis (Chinese cabbage) seeds. The plasma device used is simple. No pure gas flow system is necessary and it is easy to handle. A large number of seeds can be treated by simply scaling up the device. Plasma exposure can be a practical method for improving seed germination of crop plants important for agriculture.


Subject(s)
Germination , Mustard Plant , Plasma Gases , Seeds , Mustard Plant/growth & development , Plasma Gases/pharmacology , Seeds/growth & development , Seeds/drug effects , Atmospheric Pressure
16.
PLoS One ; 19(6): e0305345, 2024.
Article in English | MEDLINE | ID: mdl-38889132

ABSTRACT

Conducting this research contributes to a deeper understanding of the correlation between atmospheric environmental quality and lung cancer incidence, and provides the scientific basis for formulating effective environmental protection and lung cancer prevention and control strategies. Lung cancer incidence in China has strong spatial variation. However, few studies have systematically revealed the characteristics of the spatial variation in lung cancer incidence, and have explained the causes of this spatial variation in lung cancer incidence from the perspectives of multiple components of the atmospheric environment to explain this spatial variation in lung cancer incidence. To address research limitations, we first analyze the spatial variation and spatial correlation characteristics of lung cancer incidence in China. Then, we build a spatial regression model using GeoDa software with lung cancer incidence as the dependent variable, five atmospheric environment factors-particulate matter 2.5 (PM2.5) concentration, temperature, atmospheric pressure, and elevation as explanatory variables, and four socio-economic characteristics as control variables to systematically analyze the influence and intensity of these factors on lung cancer incidence. The results show that lung cancer incidence in China has apparent changes in geographical and spatial unevenness, and spatial autocorrelation characteristics. In China, the lung cancer incidence is relatively high in Northeast China, while some areas of high lung cancer incidence still exist in Central China, Southwest China and South China, although the overall lung cancer incidence is relatively low. The atmospheric environment significantly affects lung cancer incidence. Different elements of the atmospheric environment vary in the direction and extent of their influence on the development of lung cancer. A 1% increase in PM2.5 concentration is associated with a level of 0.002975 increase in lung cancer incidence. Atmospheric pressure positively affects lung cancer incidence, and an increase in atmospheric pressure by 1% increases lung cancer incidence by a level of 0.026061. Conversely, a 1% increase in temperature is linked to a level of 0.006443 decreases in lung cancer incidence, and a negative correlation exists between elevation and lung cancer incidence, where an increase in elevation by 1% correlates with a decrease in lung cancer incidence by a level of 0.000934. The core influencing factors of lung cancer incidence in the seven geographical divisions of China exhibit variations. This study facilitates our understanding of the spatial variation characteristics of lung cancer incidence in China on a finer scale, while also offering a more diverse perspective on the impact of the atmospheric environment on lung cancer incidence.


Subject(s)
Lung Neoplasms , Particulate Matter , Lung Neoplasms/epidemiology , Lung Neoplasms/etiology , China/epidemiology , Incidence , Humans , Particulate Matter/analysis , Particulate Matter/adverse effects , Atmosphere/chemistry , Atmospheric Pressure , Temperature , Spatial Analysis , Air Pollution/adverse effects , Air Pollution/analysis
17.
Int J Mol Sci ; 25(11)2024 May 30.
Article in English | MEDLINE | ID: mdl-38892174

ABSTRACT

Foodborne diseases can be attributed not only to contamination with bacterial or fungal pathogens but also their associated toxins. Thus, to maintain food safety, innovative decontamination techniques for toxins are required. We previously demonstrated that an atmospheric-pressure dielectric-barrier discharge (APDBD) plasma generated by a roller conveyer plasma device is effective at inactivating bacteria and fungi in foods. Here, we have further examined whether the roller conveyer plasma device can be used to degrade toxins produced by foodborne bacterial pathogens, including aflatoxin, Shiga toxins (Stx1 and Stx2), enterotoxin B and cereulide. Each toxin was spotted onto an aluminum plate, allowed to dry, and then treated with APDBD plasma applied by the roller conveyer plasma device for different time periods. Assessments were conducted using a competitive enzyme-linked immunosorbent assay (ELISA) and liquid chromatography-tandem mass spectrometry (LC-MS/MS). The results demonstrate a significant time-dependent decrease in the levels of these toxins. ELISA showed that aflatoxin B1 concentrations were reduced from 308.6 µg/mL to 74.4 µg/mL within 1 min. For Shiga toxins, Stx1 decreased from 913.8 µg/mL to 65.1 µg/mL, and Stx2 from 2309.0 µg/mL to 187.6 µg/mL within the same time frame (1 min). Enterotoxin B levels dropped from 62.67 µg/mL to 1.74 µg/mL at 15 min, and 1.43 µg/mL at 30 min, but did not display a significant decrease within 5 min. LC-MS/MS analysis verified that cereulide was reduced to below the detection limit following 30 min of APDBD plasma treatment. Taken together, these findings highlight that a range of foodborne toxins can be degraded by a relatively short exposure to plasma generated by an APDBD using a roller conveyer device. This technology offers promising advancements in food safety, providing a novel method to alleviate toxin contamination in the food processing industry.


Subject(s)
Atmospheric Pressure , Tandem Mass Spectrometry , Enterotoxins , Depsipeptides/chemistry , Food Microbiology/methods , Chromatography, Liquid/methods , Foodborne Diseases/prevention & control , Foodborne Diseases/microbiology , Enzyme-Linked Immunosorbent Assay , Food Contamination/analysis , Plasma Gases/chemistry , Aflatoxin B1
18.
PeerJ ; 12: e17322, 2024.
Article in English | MEDLINE | ID: mdl-38903884

ABSTRACT

Dissolved oxygen is fundamental for chemical and biochemical processes occurring in natural waters and critical for the life of aquatic organisms. Many organisms are responsible for altering organic matter and oxygen transfers across ecosystem or habitat boundaries and, thus, engineering the oxygen balance of the system. Due to such Lemna features as small size, simple structure, vegetative reproduction and rapid growth, as well as frequent mass occurrence in the form of thick mats, they make them very effective in oxygenating water. The research was undertaken to assess the impact of various species of duckweed (L. minor and L. trisulca) on dissolved oxygen content and detritus production in water and the role of ecological factors (light, atmospheric pressure, conductivity, and temperature) in this process. For this purpose, experiments were carried out with combinations of L. minor and L. trisulca. On this basis, the content of oxygen dissolved in water was determined depending on the growth of duckweed. Linear regression models were developed to assess the dynamics of changes in oxygen content and, consequently, organic matter produced by the Lemna. The research showed that the presence of L. trisulca causes an increase in dissolved oxygen content in water. It was also shown that an increase in atmospheric pressure had a positive effect on the ability of duckweed to produce oxygen, regardless of its type. The negative correlation between conductivity and water oxygenation, obtained in conditions of limited light access, allows us to assume that higher water conductivity limits oxygen production by all combinations of duckweeds when the light supply is low. Based on the developed models, it was shown that the highest increase in organic matter would be observed in the case of mixed duckweed and the lowest in the presence of the L. minor species, regardless of light conditions. Moreover, it was shown that pleustophytes have different heat capacities, and L. trisulca has the highest ability to accumulate heat in water for the tested duckweed combinations. The provided knowledge may help determine the good habitat conditions of duckweed, indicating its role in purifying water reservoirs as an effect of producing organic matter and shaping oxygen conditions with the participation of various Lemna species.


Subject(s)
Araceae , Oxygen , Araceae/metabolism , Araceae/growth & development , Oxygen/metabolism , Ecosystem , Temperature , Water/metabolism , Atmospheric Pressure , Light
19.
Funct Plant Biol ; 512024 Jun.
Article in English | MEDLINE | ID: mdl-38902906

ABSTRACT

This study reveals a new acclimation mechanism of the eukaryotic unicellular green alga Chlorella vulgaris in terms of the effect of varying atmospheric pressures on the structure and function of its photosynthetic apparatus using fluorescence induction measurements (JIP-test). The results indicate that low (400mbar) and extreme low (2 atmosphere (simulating the Mars atmosphere), reveals that the impact of extremely low atmospheric pressure on PQ mobility within the photosynthetic membrane, coupled with the low density of an almost 100% CO2 Mars-like atmosphere, results to a similar photosynthetic efficiency to that on Earth. These findings pave the way for the identification of novel functional acclimation mechanisms of microalgae to extreme environments that are vastly distinct from those found on Earth.


Subject(s)
Acclimatization , Atmospheric Pressure , Chlorella vulgaris , Mars , Microalgae , Photosynthesis , Microalgae/physiology , Chlorella vulgaris/physiology , Exobiology , Atmosphere/chemistry , Extraterrestrial Environment
20.
Int J Mol Sci ; 25(12)2024 Jun 17.
Article in English | MEDLINE | ID: mdl-38928343

ABSTRACT

Increasing the number of resistant bacteria resistant to treatment is one of the leading causes of death worldwide. These bacteria are created in wounds and injuries and can be transferred through hospital equipment. Various attempts have been made to treat these bacteria in recent years, such as using different drugs and new sterilization methods. However, some bacteria resist drugs, and other traditional methods cannot destroy them. In the meantime, various studies have shown that cold atmospheric plasma can kill these bacteria through different mechanisms, making cold plasma a promising tool to deactivate bacteria. This new technology can be effectively used in the food industry because it has the potential to inactivate microorganisms such as spores and microbial toxins and increase the wettability and printability of polymers to pack fresh and dried food. It can also increase the shelf life of food without leaving any residue or chemical effluent. This paper investigates cold plasma's potential, advantages, and disadvantages in the food industry and sterilization.


Subject(s)
Food Packaging , Plasma Gases , Food Packaging/methods , Plasma Gases/pharmacology , Sterilization/methods , Atmospheric Pressure , Food Preservation/methods , Bacteria/drug effects
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