1.
Bol Med Hosp Infant Mex
; 47(10): 694-7, 1990 Oct.
Article
in Spanish
| MEDLINE
| ID: mdl-2278646
ABSTRACT
Below is report on our experience using a relatively new benzodiazepine as treatment for refractory epilepsy in 30 children. All of the patients had a severely fixed encephalopathy; 17 presented mixed epilepsy, 9 had Lennox-Gastaut syndrome and 4 others, West Syndrome. The seizures were totally controlled in 20% of the children; in a proportion superior to 75%, seizures were decreased in 46% of the patients. There were positive results in 6% of the cases and side-effects were seen in 13%. The usefulness of the clobazam as a co-adjuvant medication in the control of refractory epileptic seizures was demonstrated since the number of seizures decreased from 15 to 3 per day.
Subject(s)
Anti-Anxiety Agents , Anticonvulsants/therapeutic use , Benzodiazepines , Benzodiazepinones/therapeutic use , Epilepsy/drug therapy , Adolescent , Anticonvulsants/adverse effects , Benzodiazepinones/adverse effects , Chemical Phenomena , Chemistry , Child , Child, Preschool , Clobazam , Epilepsy/etiology , Follow-Up Studies , Humans , Infant , Statistics as Topic
2.
Arq Neuropsiquiatr
; 31(4): 283-9, 1973 Dec.
Article
in Portuguese
| MEDLINE
| ID: mdl-4206383
Subject(s)
Anticonvulsants/adverse effects , Benzodiazepinones/adverse effects , Epilepsy, Absence/chemically induced , Epilepsy/drug therapy , Phenobarbital/adverse effects , Phenytoin/adverse effects , Anticonvulsants/therapeutic use , Benzodiazepinones/therapeutic use , Child , Child, Preschool , Chlorobenzenes/adverse effects , Chlorobenzenes/therapeutic use , Drug Therapy, Combination , Evaluation Studies as Topic , Female , Humans , Male , Nitro Compounds/adverse effects , Nitro Compounds/therapeutic use , Phenobarbital/therapeutic use , Phenytoin/therapeutic use
3.
J Bras Psiquiatr
; 20(3): 237-47, 1971.
Article
in Portuguese
| MEDLINE
| ID: mdl-4950635