Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 20 de 9.129
Filter
1.
Langenbecks Arch Surg ; 409(1): 206, 2024 Jul 05.
Article in English | MEDLINE | ID: mdl-38967821

ABSTRACT

BACKGROUND: There is a lack of literature on the length of the terminal ileum to be resected in right hemicolectomy for colon cancer. Therefore, we aimed to determine the mean ileal loop length and the effect of this variation on postoperative complications and long-term oncological outcomes in patients who underwent right hemicolectomy. METHODS: Right hemicolectomy surgeries performed for colon cancer in a tertiary care hospital between January 2011 and December 2018 were retrospectively analyzed from a prospective database. Two patient groups were established based on the mean length of the resected ileum above and below 7 cm. The two groups were compared for clinicopathological data, postoperative complications, mortality, long-term overall survival (OS) and disease-free survival (DFS). The factors contributing to OS and DFS were analyzed. RESULTS: The study included 217 patients. Body mass index (BMI) values were significantly higher in the ileum resection length > 7 cm group (p = 0.009). Pathological N stage, tumor diameter, and number of metastatic lymph nodes were significantly higher in the ileum resection length > 7 cm group (p = 0.001, p = 0.001, and p = 0.026, respectively). There was no significant difference for postoperative complication and mortality rates between the two groups. The mean follow-up period was 61.2 months (2-120) in all patients. The total number of deaths was 29 (11.7%) while the 60-month OS was 83.5% and 50-month DFS was 81.8%. There was no significant difference between the groups in terms of OS and DFS rates (p > 0.05). CONCLUSIONS: Excessive resection of the distal ileum in right hemicolectomy does not provide any benefit in terms of prognosis and complications.The ileum resection length and values close to it in our study appear to be sufficient.


Subject(s)
Colectomy , Colonic Neoplasms , Ileum , Postoperative Complications , Humans , Male , Colonic Neoplasms/surgery , Colonic Neoplasms/pathology , Colonic Neoplasms/mortality , Female , Colectomy/methods , Colectomy/adverse effects , Postoperative Complications/etiology , Postoperative Complications/epidemiology , Middle Aged , Ileum/surgery , Ileum/pathology , Aged , Retrospective Studies , Prognosis , Adult , Survival Rate , Neoplasm Staging , Aged, 80 and over
3.
Obes Res Clin Pract ; 18(3): 232-234, 2024.
Article in English | MEDLINE | ID: mdl-38944551

ABSTRACT

Transit bipartition (TB) emerges as a bariatric surgery alternative to Duodenal Switch (DS), emphasizing complete intestinal access and reduced malabsorption. By directly stimulating the distal ileum, TB promotes weight loss while preserving endoscopic duodenal access. This technique enhances anorexigenic hormones, aiding in satiety and weight loss, with lower malnutrition risks than DS. TB shows favorable short-term outcomes in weight management and comorbidity reduction, serving as a simpler, less malabsorptive option than DS. Nonetheless, long-term studies are essential for comprehensive efficacy assessment.


Subject(s)
Bariatric Surgery , Duodenum , Weight Loss , Humans , Bariatric Surgery/methods , Duodenum/surgery , Obesity, Morbid/surgery , Ileum/surgery , Treatment Outcome
4.
Pediatr Surg Int ; 40(1): 145, 2024 Jun 01.
Article in English | MEDLINE | ID: mdl-38822835

ABSTRACT

PURPOSE: Preserving the ileocecal valve (ICV) has shown significant benefits. We present our experience with 18 infants who underwent ileocecal valve-preservation ileocecostomy (IVPI) with an extremely short distal ileum after primary ileostomy. METHODS: A retrospective analysis was conducted on IVPI cases between 2014 and 2020. Medical records were reviewed, including birth weight, age, primary diseases, length of ileus stump, surgical time and procedure, time to enteral feeding, postoperative hospital stay, and complications. RESULTS: Eighteen patients (male: female = 12:6, median birth weight 1305 (750-4000) g, median gestational age 29 + 5 (27 + 6-39 + 6) weeks) were included in the analysis. Causes of surgery included necrotizing enterocolitis (13), ileocecal intestinal atresia (1), ileum volvulus (2), meconium peritonitis (1), and secondary intestinal fistula (1). The median corrected age of ileostomy closure was 3.2 months (2.0-8.0 months). The distance from the distal ileal stoma to the ICV ranged from 0.5 to 2 cm. The median length of the residual bowel was 90 cm (50-130 cm). ICV-plasty was performed in 3 cases due to secondary ICV occlusion or stenosis. All patients resumed feeding within 6 to 11 days after surgery. The postoperative hospital stay ranged from 12 to 108 days (median: 16.5 days). Complications included incisional infections in 2 cases, anastomotic stricture and adhesive ileus in 1 case, nosocomial sepsis and septic shock in 1 case. All children showed normal growth and development during a 6-65 month follow-up. CONCLUSIONS: IVPI is safe and feasible for infants with an extremely short distal ileal stump. ICV-plasty could be applicable for cases with ileocecal occlusion/stenosis.


Subject(s)
Ileocecal Valve , Ileostomy , Humans , Male , Retrospective Studies , Ileocecal Valve/surgery , Female , Ileostomy/methods , Infant, Newborn , Infant , Ileum/surgery , Postoperative Complications
5.
Isr Med Assoc J ; 26(6): 361-368, 2024 Jun.
Article in English | MEDLINE | ID: mdl-38884309

ABSTRACT

BACKGROUND: Although minimally invasive surgery for Crohn's disease has been validated in previous studies, most of those reports have referred to laparoscopic-assisted procedures with an extra-corporeal anastomosis. OBJECTIVES: To evaluate the short- and long-term outcomes of total laparoscopic ileocolic resection with an intracorporeal anastomosis for Crohn's disease patients. METHODS: We conducted a single-center retrospective review of all patients who underwent primary ileocolic resection for Crohn's disease between 2010 and 2021. Group A included 34 patients who underwent total laparoscopic ileocolic resection with intracorporeal anastomosis. Group B comprised 144 patients who underwent an open or laparoscopic-assisted procedure. RESULTS: No differences were noted in operative time (mean 167 minutes vs. 152 minutes, P = 0.122), length of stay (median 6.4 days vs. 7.5 days, P = 0.135), readmission rates (11.8% vs. 13.2%, P = 1), and microscopic involvement of surgical margins (7.7% vs. 18.5%, P = 0.249). Group A had significantly fewer postoperative surgical site infections (2.9% vs. 22.2% respectively, P = 0.013), with no differences in other complications prevalence. After a median follow-up of 46 months, there were similar rates of endoscopic recurrence (47.1% vs. 51.4%, P = 0.72), clinical recurrence (35.3% vs. 47.9%, P = 0.253), and surgical recurrence (2.9% vs. 4.9%, P = 0.722). CONCLUSIONS: Total laparoscopic ileocolic resection with intracorporeal anastomosis for Crohn's disease is safe and resulted in favorable outcomes in terms of postoperative wound healing. The long-term disease recurrence rates were like those of laparoscopic-assisted and open ileocolic resection.


Subject(s)
Anastomosis, Surgical , Crohn Disease , Ileum , Laparoscopy , Length of Stay , Humans , Crohn Disease/surgery , Laparoscopy/methods , Anastomosis, Surgical/methods , Male , Female , Retrospective Studies , Adult , Ileum/surgery , Length of Stay/statistics & numerical data , Operative Time , Colon/surgery , Treatment Outcome , Middle Aged , Colectomy/methods , Colectomy/adverse effects , Postoperative Complications/epidemiology
6.
Urol Pract ; 11(4): 753-759, 2024 Jul.
Article in English | MEDLINE | ID: mdl-38899673

ABSTRACT

INTRODUCTION: We aimed to investigate the differences in perioperative outcomes, especially ureteroenteric strictures, between patients who underwent a stented ureteroenteric anastomosis at the time of robot-assisted radical cystectomy (RARC) and ileal conduit vs those who did not. METHODS: A retrospective review of our RARC database was performed (2009-2023). Patients were divided into those who received stented ureteroenteric anastomosis vs those who did not. Propensity score matching was performed in the ratio of 3 (stented ureteroenteric anastomosis) to 1 (stent-free) in terms of age, gender, BMI, race, American Society of Anesthesiologists score, neoadjuvant chemotherapy, Charlson Comorbidity Index, prior radiation therapy, previous abdominal surgery history, clinical T3/clinical T4 stage, preoperative metastasis, and preoperative hydronephrosis. A cumulative incidence curve was used to depict ureteroenteric strictures and a Cox regression model was used to identify variables associated with ureteroenteric strictures. RESULTS: Four hundred eighty-eight patients underwent RARC, 366 individuals underwent a stented ureteroenteric anastomosis, and 122 patients underwent a stent-free approach. There was no significant difference in 90-day overall complications, high-grade complications, readmissions, UTIs, leakage, and ileus (P > .05). Ureteroenteric strictures occurred at a rate of 13% and 18% at 1 and 2 years, respectively in the stented group, vs 7% and 10% in the stent-free group (P = .05). Stent placement was significantly associated with ureteroenteric strictures. CONCLUSIONS: Stent-free ureteroenteric anastomosis was associated with fewer strictures following RARC and ileal conduit.


Subject(s)
Anastomosis, Surgical , Cystectomy , Postoperative Complications , Robotic Surgical Procedures , Stents , Urinary Bladder Neoplasms , Urinary Diversion , Humans , Male , Female , Urinary Diversion/adverse effects , Urinary Diversion/methods , Retrospective Studies , Cystectomy/adverse effects , Cystectomy/methods , Anastomosis, Surgical/adverse effects , Anastomosis, Surgical/methods , Aged , Robotic Surgical Procedures/adverse effects , Robotic Surgical Procedures/methods , Stents/adverse effects , Constriction, Pathologic/etiology , Middle Aged , Postoperative Complications/etiology , Postoperative Complications/epidemiology , Urinary Bladder Neoplasms/surgery , Ureter/surgery , Ureteral Obstruction/surgery , Ureteral Obstruction/etiology , Ileum/surgery
7.
Medicine (Baltimore) ; 103(23): e38405, 2024 Jun 07.
Article in English | MEDLINE | ID: mdl-38847709

ABSTRACT

RATIONALE: Ileal perforation caused by the insertion of a drainage tube is a rare complication. Hence, the utilization of surgical drains in abdominal surgery remains controversial. At present, there is a trend to reduce the utilization of drains in abdominal surgery, although certain situations may necessitate their application. PATIENT CONCERNS: A 25-year-old Chinese woman presented with a history of right lower abdominal pain persisting for 10 days. Imaging examinations, including abdominal computed tomography and ultrasound, identified low-density lesions measuring 10 × 8 × 8cm3 in the right lower abdomen, which are consistent with perforated appendicitis complicated by a peri-appendiceal abscess. A laparoscopic appendectomy was carried out. On the 5th postoperative day, the drainage fluid changed to a grass-green color (80mL). Imaging with retrograde contrast through the drainage tube revealed that the 26 Fr silicon rubber drainage tube tip was positioned 50cm away from the ileocecal junction within the ileum. Both the ileal and ileocecal regions appeared well-developed. INTERVENTION AND OUTCOMES: Oral intake was suspended, and the patient received antacids, somatostatin, antibiotics, and total parenteral nutrition. On the 19th postoperative day, a follow-up imaging procedure using retrograde contrast through the drainage tube indicated that the tube tip was sealed. The treatment concluded on day 33 postoperatively, and the patient was discharged. DISCUSSION AND CONCLUSION: Ileal perforation due to an abdominal drainage tube following laparoscopic appendectomy constitutes a rare but serious complication. However, due to the adhesion and inflammatory changes around the abscess, laparoscopic dissection becomes a challenging and risky process, and the surgical skills and experiences are particularly important. Removing the abdominal drainage tube promptly based on the characteristics of the drainage fluid is recommended. The findings provide valuable insights for surgeons navigating similar challenges.


Subject(s)
Appendectomy , Appendicitis , Drainage , Ileum , Laparoscopy , Humans , Female , Adult , Appendectomy/methods , Appendectomy/adverse effects , Drainage/methods , Laparoscopy/methods , Laparoscopy/adverse effects , Appendicitis/surgery , Ileum/surgery , Intestinal Perforation/etiology , Intestinal Perforation/surgery , Postoperative Complications/etiology , Postoperative Complications/surgery
8.
Sci Rep ; 14(1): 13247, 2024 06 10.
Article in English | MEDLINE | ID: mdl-38853155

ABSTRACT

The primary objective of this study was to compare short-term outcomes between Intracorporeal ileocolic anastomosis (IIA) and extracorporeal ileocolic anastomosis (EIA) after laparoscopic right hemicolectomy in patients with visceral obesity. The secondary objective was to identify risk factors associated with prolonged postoperative ileus (PPOI) after laparoscopic right hemicolectomy. This single-center retrospective study analyzed visceral obesity patients who underwent laparoscopic right hemicolectomy for primary bowel cancer between January 2020 and June 2023. Patients were categorized into IIA and EIA groups based on the type of anastomosis, and a 1:1 propensity score-matched analysis was performed. A total of 129 patients were initially included in this study, with 45 patients in each group following propensity score matching. The IIA group had significantly longer anastomosis times (p < 0.001), shorter incision length (p < 0.001), and shorter length of stay (p = 0.003) than the EIA group. Meanwhile, the IIA group showed a shorter time to first flatus (p = 0.044) and quicker tolerance of a solid diet (p = 0.030). On multivariate analysis, postoperative use of opioid analgesics is an independent risk factor for PPOI (OR: 3.590 95% CI 1.033-12.477, p = 0.044), while IIA is an independent protective factor (OR: 0.195 95% CI 0.045-0.843, p = 0.029). IIA remains a safe and feasible option for visceral obesity patients. It is also associated with a quicker recovery of bowel function and shorter length of stay when compared to EIA. Additionally, IIA is an independent protective factor for PPOI.


Subject(s)
Anastomosis, Surgical , Colectomy , Laparoscopy , Obesity, Abdominal , Postoperative Complications , Humans , Male , Female , Middle Aged , Anastomosis, Surgical/methods , Anastomosis, Surgical/adverse effects , Obesity, Abdominal/surgery , Retrospective Studies , Laparoscopy/methods , Laparoscopy/adverse effects , Postoperative Complications/etiology , Postoperative Complications/epidemiology , Treatment Outcome , Aged , Colectomy/adverse effects , Colectomy/methods , Ileum/surgery , Colon/surgery , Risk Factors , Length of Stay , Ileus/etiology
9.
Langenbecks Arch Surg ; 409(1): 195, 2024 Jun 21.
Article in English | MEDLINE | ID: mdl-38904793

ABSTRACT

PURPOSE: SASI (single anastomosis sleeve ileal) bypass can lead to nutritional deficiencies, including disorders of iron metabolism and anemia. This study aims to evaluate the effect of SASI bypass on weight loss, anemia, and iron deficiency in patients with obesity during the follow-up period. METHODS: This study is a retrospective analysis of prospectively collected data from patients who underwent SASI bypass at our hospital between January 2020 and February 2022. RESULTS: The mean age of the patients was 42 years (range 22-58). The average duration of the follow-up period was 26 months. The mean percentage of excess weight loss (%EWL) was 90.1%, and total weight loss (%TWL) was 30.5%. During the postoperative observation period, anemia was identified in ten patients (25%), comprising 70% with normocytic anemia, 10% with microcytic anemia, and two macrocytic anemia cases (20%). Iron deficiency was observed in two patients (5%). CONCLUSION: SASI bypass is an effective bariatric procedure in weight loss outcomes. However, there may be an increased risk of anemia and iron metabolism disruptions associated with this procedure. The common limb length (250 vs. 300 cm) did not significantly impact hemoglobin, iron, TIBC, ferritin levels, or anemia incidence among patients undergoing SASI bypass. The decrease in postoperative ferritin levels signifies a depletion in tissue iron reserves, thereby emphasizing the necessity for surveillance of iron homeostasis parameters following SASI bypass.


Subject(s)
Ileum , Weight Loss , Humans , Adult , Female , Male , Middle Aged , Retrospective Studies , Ileum/surgery , Postoperative Complications/etiology , Obesity, Morbid/surgery , Obesity, Morbid/complications , Anemia , Anastomosis, Surgical , Bariatric Surgery/methods , Bariatric Surgery/adverse effects , Young Adult , Anemia, Iron-Deficiency , Iron/metabolism , Iron/blood
10.
BMC Urol ; 24(1): 118, 2024 Jun 10.
Article in English | MEDLINE | ID: mdl-38858691

ABSTRACT

PURPOSE: To present the experience of ileal ureter with ileocystoplasty (IUC), and compare the outcomes of IUC in minimally invasive procedures to open procedures. PATIENTS AND METHODS: From December 2017 to April 2023, twenty patients underwent IUC in open or minimally invasive (including laparoscopic and robotic) procedures. The baseline characteristics, perioperative data and follow-up outcomes were collected. Success was defined as relief of clinical symptoms, stable postoperative serum creatine and absence of radiographic obstruction. The perioperative and follow-up outcomes of open procedures and minimally invasive procedures were compared. RESULTS: The etiology included pelvic irradiation (14/20), urinary tuberculosis (3/20) and surgical injury (3/20). Bilateral ureter strictures were repaired in 15 cases. The surgeries conducted consisted of open procedures in 9 patients and minimally invasive procedures in 11 patients. Compared to open procedures, minimally invasive surgeries had less median estimated blood loss (EBL) (100 ml vs. 300 min, p = 0.010) and shorter postoperative hospitalization (27 d vs. 13 d, p = 0.004). Two patients in the open group experienced grade 3 complications (sigmoid fistula and acute cholecystitis in one patient, and pulmonary embolism in another patient). Over a median follow-up period of 20.1 months, the median bladder functional capacity was 300 ml, with a 100% success rate of IUC. CONCLUSION: IUC is feasible in both open and minimally invasive procedures, with acceptable complications and a high success rate. Minimally invasive procedures can have less EBL and shorter postoperative hospitalization than open procedure. However, prospective studies with larger groups and longer follow-up are needed.


Subject(s)
Ileum , Minimally Invasive Surgical Procedures , Ureter , Urinary Bladder , Urologic Surgical Procedures , Humans , Male , Female , Ileum/surgery , Adult , Treatment Outcome , Middle Aged , Urinary Bladder/surgery , Urologic Surgical Procedures/methods , Ureter/surgery , Minimally Invasive Surgical Procedures/methods , Retrospective Studies , Time Factors , Laparoscopy/methods , Aged , Robotic Surgical Procedures
12.
Pediatr Surg Int ; 40(1): 131, 2024 May 10.
Article in English | MEDLINE | ID: mdl-38730091

ABSTRACT

PURPOSE: To evaluate the urodynamic changes in patients who have undergone colocystoplasty (CCP), gastrocystoplasty (GCP) and ileocystoplasty (ICP) in a retrospective study. Changes in urinary continence, incidence of pathologic contractions before and after augmentation, alterations of urodynamic parameters were also examined. METHODS: Eighty-four patients were included in the study who underwent bladder augmentation between 1987 and 2017. Group I: 35 patients with CCP. Group II: 18 patients with GCP. Group III: 31 patients with ICP. Cystometry was performed at 3, 6, and every 12 months, then biannually after augmentation. Pre- and postoperative urodynamic changes were analysed statistically. RESULTS: In Group I, two patients and in Group III, one patient remained incontinent after CCP and ICP. Bladder capacity increased significantly, maximal intra-vesical pressure decreased and compliance improved in all groups (p < 0.001). Postoperative studies showed pathologic contractions in the augmented bladder in half of the patients with GCP, in 43% of patients after CCP and 26% of patients with ICP. CONCLUSION: From the urodynamic point of view, ileum is the most adequate option in the long term. Contractions after augmentation might be caused by the remaining peristalsis of the detubularised segment. Further investigations are needed to evaluate pathologic contractions that remained after detubularisation.


Subject(s)
Ileum , Urinary Bladder , Urodynamics , Humans , Retrospective Studies , Female , Male , Urinary Bladder/physiopathology , Urinary Bladder/surgery , Child , Ileum/surgery , Ileum/physiopathology , Adolescent , Colon/surgery , Colon/physiopathology , Child, Preschool , Stomach/surgery , Stomach/physiopathology , Urologic Surgical Procedures/methods , Infant
13.
Asian J Endosc Surg ; 17(3): e13323, 2024 Jul.
Article in English | MEDLINE | ID: mdl-38735654

ABSTRACT

There is no optimal reconstruction after radical distal esophagectomy for cancers of the esophagogastric junction. We designed a novel reconstruction technique using pedicled ileocolic interposition with intrathoracic anastomosis between the esophagus and the elevated ileum. Two patients underwent the surgery. Case 1 was a 70-year-old man with esophagogastric junction adenocarcinoma with 3 cm of esophageal invasion. Case 2 was a 70-year-old man with squamous cell carcinoma of the esophagogastric junction; the epicenter of which was located just at the junction. These two patients underwent radical distal esophagectomy and pedicled ileocolic interposition with intrathoracic anastomosis. They were discharged on postoperative days 17 and 14, respectively, with no major complication. Pedicled ileocolic interposition is characterized by sufficient elevation and perfusion of the ileum, which is fed by the ileocolic artery and vein. As a result, we can generally adapt this reconstruction method to most curable esophagogastric junction cancers.


Subject(s)
Adenocarcinoma , Anastomosis, Surgical , Carcinoma, Squamous Cell , Esophageal Neoplasms , Esophagectomy , Esophagogastric Junction , Ileum , Humans , Male , Esophagogastric Junction/surgery , Aged , Esophagectomy/methods , Esophageal Neoplasms/surgery , Anastomosis, Surgical/methods , Carcinoma, Squamous Cell/surgery , Adenocarcinoma/surgery , Ileum/surgery , Ileum/transplantation , Plastic Surgery Procedures/methods , Colon/surgery , Colon/transplantation , Surgical Flaps
14.
J Gastrointest Surg ; 28(5): 640-650, 2024 May.
Article in English | MEDLINE | ID: mdl-38704201

ABSTRACT

BACKGROUND: Single-anastomosis metabolic/bariatric surgery procedures may lessen the incidence of anastomotic complications. This study aimed to evaluate the feasibility and safety of performing side-to-side duodenoileal (DI) bipartition using magnetic compression anastomosis (MCA). In addition, preliminary efficacy, quality of life (QoL), and distribution of food through the DI bipartition were evaluated. METHODS: Patients with a body mass index (BMI) of ≥35.0 to 50.0 kg/m2 underwent side-to-side DI bipartition with the magnet anastomosis system (MS) with sleeve gastrectomy (SG). By endoscopic positioning, a distal magnet (250 cm proximal to the ileocecal valve) and a proximal magnet (first part of the duodenum) were aligned with laparoscopic assistance to inaugurate MCA. An isotopic study assessed transit through the bipartition. RESULTS: Between March 14, 2022 to June 1, 2022, 10 patients (BMI of 44.2 ± 1.3 kg/m2) underwent side-to-side MS DI. In 9 of 10 patients, an SG was performed concurrently. The median operative time was 161.0 minutes (IQR, 108.0-236.0), and the median hospital stay was 3 days (IQR, 2-40). Paired magnets were expelled at a median of 43 days (IQR, 21-87). There was no device-related serious advanced event within 1 year. All anastomoses were patent with satisfactory diameters after magnet expulsion and at 1 year. Respective BMI, BMI reduction, and total weight loss were 28.9 ± 1.8 kg/m2, 15.2 ± 1.8 kg/m2, and 34.2% ± 4.1%, respectively. Of note, 70.0% of patients reported that they were very satisfied. The isotopic study found a median of 19.0% of the meal transited through the ileal loop. CONCLUSION: Side-to-side MCA DI bipartition with SG in adults with class II to III obesity was feasible, safe, and efficient with good QoL at 1-year follow-up. Moreover, 19% of ingested food passed directly into the ileum.


Subject(s)
Anastomosis, Surgical , Duodenum , Feasibility Studies , Gastrectomy , Magnets , Humans , Gastrectomy/methods , Male , Female , Adult , Middle Aged , Duodenum/surgery , Anastomosis, Surgical/methods , Follow-Up Studies , Obesity, Morbid/surgery , Ileum/surgery , Quality of Life , Laparoscopy/methods , Body Mass Index , Operative Time , Bariatric Surgery/methods , Treatment Outcome , Gastrointestinal Transit
16.
Int J Urol ; 31(7): 813-818, 2024 Jul.
Article in English | MEDLINE | ID: mdl-38644653

ABSTRACT

AIM OF THE STUDY: The aim of our study is to evaluate the difference in stricture rate between matched groups of Bricker and Wallace techniques for ureteroileal anastomosis. PATIENTS AND METHODS: A retrospective analysis of patients undergoing urinary diversion (UD) with Bricker and Wallace ureteroileal anastomosis at two university hospitals. Two groups of Bricker and Wallace patients were matched in a 1:1 ratio based on the age, sex, body mass index (BMI), Charlson comorbidity index (CCI), preoperative hydronephrosis, prior radiation therapy or abdominal surgery, pathologic T and N stages and 30-days-Clavien grade complications≥III. A multivariable Cox regression analysis was conducted to identify predictors of ureteroenteric stricture (UES) in all patients. RESULTS: Overall, 740 patients met the inclusion criteria and 209 patients in each group were propensity matched. At a similar median follow-up of 25 months, UES was detected in 25 (12%) and 30 (14.4%) patients in Bricker and Wallace groups, respectively (p = 0.56). However, only one patient in the Bricker group developed a bilateral stricture compared to 15 patients in the Wallace group, resulting in a significantly higher number of affected renal units in the Wallace group: 45 (10.7%) versus only 26 (6.2%) in the Bricker group (p = 0.00). On multivariable extended Cox analysis, prior radiotherapy, presence of T4 pelvic malignancy and nodal positive disease were independent predictor of UES formation. CONCLUSION: The technique of ureteroileal anastomosis itself does not increase the rate of stricture; however, conversion of two renal units into one is associated with a higher incidence of bilateral upper tract involvement.


Subject(s)
Anastomosis, Surgical , Ileum , Propensity Score , Ureter , Urinary Diversion , Humans , Male , Female , Retrospective Studies , Middle Aged , Anastomosis, Surgical/adverse effects , Aged , Urinary Diversion/adverse effects , Urinary Diversion/methods , Ureter/surgery , Ileum/surgery , Constriction, Pathologic/etiology , Postoperative Complications/etiology , Postoperative Complications/epidemiology , Ureteral Obstruction/surgery , Ureteral Obstruction/etiology , Treatment Outcome , Follow-Up Studies
17.
Trop Doct ; 54(3): 245-247, 2024 Jul.
Article in English | MEDLINE | ID: mdl-38562099

ABSTRACT

Typhoid ileal perforation (TIP) is a common surgical emergency in low-middle income countries (LMICs). Its high surgical morbidity and mortality is due to its often late presentation or diagnosis, the patient's malnutrition, severe peritoneal contamination and unavailability of intensive care in most peripheral hospitals. This prompted the philosophy of minimizing the crisis by avoiding any repair or anastomosis, limiting the surgery in these physiologically compromised patients and performing only a temporary defunctioning ileostomy (DI) which could then be closed 10-12 weeks later.


Subject(s)
Ileostomy , Intestinal Perforation , Typhoid Fever , Humans , Intestinal Perforation/surgery , Intestinal Perforation/etiology , Typhoid Fever/complications , Ileal Diseases/surgery , Ileal Diseases/etiology , Ileal Diseases/microbiology , Ileum/surgery
18.
Histopathology ; 85(1): 182-189, 2024 Jul.
Article in English | MEDLINE | ID: mdl-38566342

ABSTRACT

CONTEXT: Carcinomas found in urinary diversion specimens are uncommon, particularly new primary tumours. New primary tumours primarily occur when the large intestine is utilised, whereas the occurrence is infrequent with the use of the ileum. These tumours include both the recurrence of primary malignancy or the development of a new primary malignancy originating from the small intestine. DESIGN: A search was performed within the pathology laboratory system to identify cases of malignancies involving ileal conduit/reconstruction from 2002 to 2022. Data on demographics, clinical details, pathology and management was recorded. RESULTS: A total of 13 male patients, with a mean age of 67 years (range = 49-81 years) were included in the study. The initial procedure performed included cystoprostatectomy (n = 10, including one case with right nephroureterectomy) and cystectomy (n = 3, including one case for bladder exstrophy) for initial diagnoses including urothelial carcinoma (n = 11; conventional, 6; sarcomatoid, 1; glandular 1; plasmacytoid, 1; micropapillary, 2) and adenocarcinoma (n = 1). The initial management included radical surgery with neoadjuvant chemotherapy/immunotherapy (n = 1), adjuvant chemotherapy (n = 3), intravesical adjuvant BCG (n = 2) and intravesical adjuvant chemotherapy (n = 1). Malignancies in ileal conduit or orthotopic ileal neobladder included recurrent urothelial carcinoma (n = 10) and new secondary adenocarcinomas (n = 3), which developed as early as 3 months (usually recurrence) and up to 13, 33 and 45 years (new primary malignancy) following primary resection. CONCLUSIONS: Utilising the ileum as conduit/neobladder presents a viable alternative for urinary diversion with a reduced malignancy risk compared to using a segment of the large intestine. However, there remains a potential for malignancy, either tumour recurrence or a new primary malignancy. In our study, tumour recurrence occurred up to 4 years following the initial diagnosis and the development of a new primary malignancy occurred up to 45 years after the initial diagnosis. Consequently, it is crucial to prioritise long-term follow-up for these patients undergoing this procedure.


Subject(s)
Urinary Bladder Neoplasms , Urinary Diversion , Humans , Male , Middle Aged , Aged , Urinary Diversion/methods , Urinary Diversion/adverse effects , Urinary Bladder Neoplasms/surgery , Urinary Bladder Neoplasms/pathology , Aged, 80 and over , Cystectomy/methods , Ileum/pathology , Ileum/surgery , Carcinoma, Transitional Cell/pathology , Carcinoma, Transitional Cell/surgery , Prostatectomy
19.
Urology ; 188: 138-143, 2024 Jun.
Article in English | MEDLINE | ID: mdl-38657870

ABSTRACT

OBJECTIVE: To examine long-term ileal ureter replacement results at over 32 years at our institution. Long segment or proximal ureteral strictures pose a challenging reconstructive problem. Ureteroureterostomy, psoas hitch, Boari flap, buccal ureteroplasty, and autotransplantation are common reconstructive techniques. We show that ileal ureter remains a lasting option. METHODS: We performed a retrospective review of patients undergoing open ileal ureter creation from 1989-2021. Patient demographics, operative history, and complications were examined. All patients were followed for changes in renal function. Demographic data were analyzed and Cox proportional hazard models were performed. RESULTS: One hundred and fifty-eight patients were identified with median follow-up time of 40 months. Eighty-one percent had a unilateral ileal ureter creation. Fifty percent were female, median age was 53.3. Twenty-seven percent of patients had radiation-induced strictures. Preoperatively, 56.3% of patients were chronic kidney disease stage 1-2 and 43.7% were stage 3-5. Post-operatively, 54% were stage 1-2 and 46% were stage 3-5. Cox proportional hazard models demonstrated no significant correlation between worsening renal function and stricture cause, bilateral repair, complications, or sex (biologically male or female). Seventy-seven percent had no 30-day complications. Clavien complications included grade 1 (18), grade 2 (4), grade 3 (9), and grade 4 (5). Long-term complications included worsening renal function (3%), incisional hernia (8.2%), and small bowel obstruction (6.9%). Five (3.1%) patients ultimately required dialysis and 5 (3.1%) patients developed metabolic acidosis. CONCLUSION: Ileal ureteral reconstruction is often a last resort for patients with complex ureteral injuries. Clinicians can be reassured by our long-term data that ileal ureteral creation is a safe treatment with good preservation of renal function and low risk of hemodialysis and metabolic acidosis.


Subject(s)
Ileum , Postoperative Complications , Ureter , Ureteral Obstruction , Humans , Female , Male , Retrospective Studies , Middle Aged , Ileum/transplantation , Ileum/surgery , Ureter/surgery , Postoperative Complications/epidemiology , Postoperative Complications/etiology , Ureteral Obstruction/surgery , Ureteral Obstruction/etiology , Adult , Kidney/surgery , Time Factors , Aged , Follow-Up Studies , Urologic Surgical Procedures/methods , Urologic Surgical Procedures/adverse effects , Plastic Surgery Procedures/methods , Plastic Surgery Procedures/adverse effects
20.
Medicine (Baltimore) ; 103(16): e37765, 2024 Apr 19.
Article in English | MEDLINE | ID: mdl-38640312

ABSTRACT

The objective was to evaluate the incidence and degree of double-J ureteral stent (DJUS) migration. Additionally, we aimed to investigate the risk factors associated with stent migration in the orthotopic neobladder group. In this retrospective study, 61 consecutive patients were included; 35 patients (45 DJUS placements) underwent radical cystectomy with orthotopic neobladder and 26 patients (35 DJUS placements) underwent urinary bladder without cystectomy between July 2021 and March 2023. All the patients were treated with a DJUS for ureteric strictures. The technical success rate was 100% in each group. The DJUS migration was significantly higher in the orthotopic neobladder group, with 22 of 45 cases (48.9%), compared to the urinary bladder group, which had 4 of 35 cases (11.4%) (P ≤ .001). Among the patients in the orthotopic neobladder group who experienced DJUS migration, stent dysfunction occurred in 18 cases (81.8%), which was statistically significant (P = .003). Multivariate logistic regression analysis revealed that only the size of the DJUS was significantly and positively associated with migration (odds ratio:10.214, P = .010). DJUS migration can easily occur in patients undergoing radical cystectomy and orthotopic neobladder, and smaller stent sizes are associated with a higher incidence of migration.


Subject(s)
Urinary Bladder Neoplasms , Urinary Diversion , Humans , Cystectomy/adverse effects , Urinary Bladder/surgery , Urinary Diversion/adverse effects , Retrospective Studies , Constriction, Pathologic/surgery , Urinary Bladder Neoplasms/surgery , Urinary Bladder Neoplasms/etiology , Risk Factors , Stents/adverse effects , Anastomosis, Surgical/adverse effects , Ileum/surgery
SELECTION OF CITATIONS
SEARCH DETAIL
...