ABSTRACT
Leptospirosis has been rarely reported in solid organ transplant recipients. We report the first case to our knowledge of leptospirosis in a liver transplant recipient who developed jaundice and renal insufficiency. We describe his favorable clinical progression and discuss the possible mechanisms involved in the more benign disease course. We also review the previously published cases of leptospirosis in solid organ transplant recipients. Although this disease does not appear to present any particularities in this context, we highlight the importance of clinical suspicion in this setting, particularly after liver transplantation.
Subject(s)
Acute Kidney Injury/drug therapy , Anti-Bacterial Agents/therapeutic use , Leptospira/isolation & purification , Leptospirosis/diagnosis , Liver Transplantation/adverse effects , Humans , Jaundice/microbiology , Leptospirosis/microbiology , Male , Middle AgedSubject(s)
Humans , Male , AIDS-Related Opportunistic Infections/pathology , HIV-1 , Histoplasmosis/pathology , Jaundice/pathology , AIDS-Related Opportunistic Infections/microbiology , Autopsy , Adrenal Glands/microbiology , Adrenal Glands/pathology , English Abstract , Histoplasma/isolation & purification , Histoplasmosis/microbiology , Jaundice/microbiology , Middle AgedABSTRACT
The case of a 58-years-old patient with AIDS is discussed. He presented a progressive disease with discomfort, abdominal pain, hiporexia, fever and weight loss. At the time of admittance in our hospital he had hepatosplenomegaly. The patient worsened and presented asthenia, fever, oedema, ascites, pulmonary congestion and finally jaundice and died. Autopsy findings were indicative of disseminated histoplasmosis with pseudotumoral appearance of the adrenal glands.