[Fleeing nazism: Alejandro Lipschütz and the cases of Alfons Nehring and Käte Pariser]. / Huir del nazismo: Alejandro Lipschütz y los casos de Alfons Nehring y Käte Pariser.

This paper studies a shelter network for Jewish scientists displaced by nazism from the archive of Alexander Lipschütz, a physiologist who lived in Chile since 1926. From the context of the anti-Semitic persecution and the way in which it affected German science and their universities, we have analyzed letters sent to and from Lipschütz between 1935 and 1936, with special attention to people who contacted him to flee Germany and considered Latin America as a possibility to live. We suggest this was a network of personal agencies, charged with subjectivities and intimacy, which had to take into account local anti-Semitism and academic xenophobia.

Este trabajo estudia una red de acogida para científicos judíos desplazados por el nazismo a partir del archivo de Alejandro Lipschütz, fisiólogo que vivió en Chile desde 1926. A partir del contexto de la persecución antisemita y la forma en que afectó a la ciencia y a la universidad alemanas se analizan las cartas remitidas hacia y desde Lipschütz entre 1935 y 1936, con especial atención a personas que lo contactaron para huir de Alemania y que veían en América Latina una posibilidad. Proponemos que se trata de una red de agencias personales, cargada de subjetividades e intimidad, que debía tener en cuenta el antisemitismo y la xenofobia académica local.

From Germany to Venezuela: The two careers of the Jewish-born pathologist Rudolf Jaffé (1885-1975).

The pathologist Rudolf Jaffé (1885-1975) is considered one of the most important specialists of his time - even though he had to flee from the Nazis and attempt a professional restart in South America. The article examines the concrete background of his emigration to South America and the factors that enabled Jaffé to establish pathology as a scientific discipline in Venezuela. Various archival documents and materials from the private archives of Jaffé's descendants serve as sources. These documents are supplemented by relevant secondary literature. Jaffé's career can be divided into four phases: (1) Jaffé's broad education, which qualified him for his later work in Venezuela. (2) Jaffé's professional activity at the Senckenberg Institute of Pathology in Frankfurt. (3) His career peak in Germany as head of the Institute of Pathology in Berlin-Moabit, and finally (4) his forced emigration to Venezuela, where he became the doyen of the field of pathology. It can be shown that Jaffé's great scientific success, even after his emigration, was based on three factors: his exceptional personality, his broad, multifaceted training, and the special conditions in Venezuela.

Challenges, Opportunities, and Coping in the Wake of the COVID-19 Pandemic: The Case of Jewish Communities around the World.

Against the backdrop of the COVID-19 pandemic, which lasted more than two years and included several waves, the present study focused on Jewish communities around the world, in order to understand the role of community during the pandemic. This study focused on the community mechanisms that helped community members to cope with the pandemic. To that end, between October 2021 and July 2022, in-person interviews were conducted with leaders and members of the following communities: Budapest, Hungary; Subotica, Serbia; Vienna, Austria; Bratislava, Slovakia; Vilna, Lithuania; Buenos Aires, Rosario, Salta, and Ushuaia in Argentina; and Mexico City and Cancun in Mexico. Each interview lasted between 45 min and 1.5 h. All of the interviews were audio-recorded and transcripts of those recordings were prepared. Three major themes emerged from the interviews: challenges, coping, and opportunities. Most of these themes were common to the different communities around the world. The findings of this work are discussed in terms of the concept of sense of community and resiliency theories.

[Israel and covid-19: how will the history of the epidemic in this country be written in the future?] / Israel y covid-19: ¿cómo se escribirá en el futuro la historia de la epidemia en este país?

This article attempts to hypothetically reflect on how historians of science will write their research on the development of the covid-19 pandemic in Israel in the future, within a context that includes: the political crisis experienced by the country at that time; the history of the public health institutions established from the time of the first Jewish settlers in Palestine, at the beginning of the twentieth century, and slightly modified by a law of 1994; the conceptual schemes developed during the last decades by historians of public health and pandemics in general.

El presente artículo representa un intento de reflexionar hipotéticamente sobre la manera en que los historiadores de la ciencia escribirán en el futuro sus investigaciones sobre el desarrollo de la pandemia de la covid-19 en Israel, dentro de un contexto que incluye: la crisis política que vivió el país en esos momentos; la historia de las instituciones de salud pública establecidas desde la época de los primeros colonos judíos en Palestina, a principios del siglo XX, y modificadas ligeramente por una ley de 1994; los esquemas conceptuales desarrollados durante las últimas décadas por historiadores de la salud pública y las pandemias en general.

Population-based screening of Uruguayan Ashkenazi Jews for recurrent BRCA1 and BRCA2 pathogenic sequence variants.

In Ashkenazi Jews (AJ) three recurring pathogenic sequence variants (PSVs) are detected in ~2.5% of the general population in the BRCA1 (c.68_69del = 185delAG, c.5266dup = 5382insC), and BRCA2 (c.5946del = 6174delT). Population-based screening for these PSVs in AJ women is part of the health basket in Israel. To assess the feasibility and outcome of BRCA genotyping in the Jewish population of Uruguay, AJ in the greater Montevideo area were recruited using ethically approved protocol and without pretest counseling were genotyped for the three predominant AJ PSVs in the BRCA genes. Independently confirmed PSV carriers were counseled, and genetic testing was offered to additional family members. Overall, 327 participants were enrolled: 312 (95%) female, 261 (80%) had all four grandparents AJ, and 14 (4%) women were breast cancer survivors with a mean age ± standard deviation (SD) 50 ± 11.5 years. The BRCA1 c.68_69del PSV was detected in three cancer free participants (0.92%, CI 95% 0.31-2.6), all with a suggestive family history. No carriers of the other two recurrent PSVs were detected. Online oncogenetic counseling was provided for all carriers. In conclusion, the rate of the BRCA1 c.68_69del PSV was similar with the rate in other AJ communities. AJ population BRCA genotyping screens in Uruguay seem feasible and should be promoted.

Carrier screening in the Mexican Jewish community using a pan-ethnic expanded carrier screening NGS panel.

PURPOSE: The Mexican Jewish community (MJC) is a previously uncharacterized, genetically isolated group composed of Ashkenazi and Sephardi-Mizrahi Jews who migrated in the early 1900s. We aimed to determine the heterozygote frequency of disease-causing variants in 302 genes in this population. METHODS: We conducted a cross-sectional study of the MJC involving individuals representing Ashkenazi Jews, Sephardi-Mizrahi Jews, or mixed-ancestry Jews. We offered saliva-based preconception pan-ethnic expanded carrier screening, which examined 302 genes. We analyzed heterozygote frequencies of pathogenic/likely pathogenic variants and compared them with those in the Genome Aggregation Database (gnomAD). RESULTS: We recruited 208 participants. The carrier screening results showed that 72.1% were heterozygous for at least 1 severe disease-causing variant in 1 of the genes analyzed. The most common genes with severe disease-causing variants were CFTR (16.8% of participants), MEFV (11.5%), WNT10A (6.7%), and GBA (6.7%). The allele frequencies were compared with those in the gnomAD; 85% of variant frequencies were statistically different from those found in gnomAD (P <.05). Finally, 6% of couples were at risk of having a child with a severe disorder. CONCLUSION: The heterozygote frequency of at least 1 severe disease-causing variant in the MJC was 72.1%. The use of carrier screening in the MJC and other understudied populations could help parents make more informed decisions.

Ancestral patterns of recessive dystrophic epidermolysis bullosa mutations in Hispanic populations suggest sephardic ancestry.

Recessive dystrophic epidermolysis bullosa (RDEB) is a rare genodermatosis caused by mutations in the gene coding for type VII collagen (COL7A1). More than 800 different pathogenic mutations in COL7A1 have been described to date; however, the ancestral origins of many of these mutations have not been precisely identified. In this study, 32 RDEB patient samples from the Southwestern United States, Mexico, Chile, and Colombia carrying common mutations in the COL7A1 gene were investigated to determine the origins of these mutations and the extent to which shared ancestry contributes to disease prevalence. The results demonstrate both shared European and American origins of RDEB mutations in distinct populations in the Americas and suggest the influence of Sephardic ancestry in at least some RDEB mutations of European origins. Knowledge of ancestry and relatedness among RDEB patient populations will be crucial for the development of future clinical trials and the advancement of novel therapeutics.

Health-related quality of life among Jewish older persons in Mexico and its determinants.

PURPOSE: Aging research in Mexico has significantly increased in the past decades, however, little is known on health related quality of life (HRQoL) of older adults. The aim of this study was to expand this field by examining HRQL in a representative sample of Jewish older adults in Mexico, and to investigate its association with different factors. METHODS: This was a cross-sectional survey of a random sample of community dwelling Jewish men and women aged 60 years and older. HRQoL was measured using the Short Form Health Survey (SF-36). Bivariate analysis was performed to estimate the association of scores of HRQoL and different characteristics of the study sample and multiple linear regression models were estimated using ordinary least squares (OLS), to explore determinant factors associated to HRQoL in this sample, for the eight domains of the SF-36 sub-scales separately. RESULTS: Two hundred ninety-five older persons were interviewed. Mean age was 72.7 years (SD 7.9), men made up 57% of the sample, 67% were married and 52% reported living with another person, mostly the spouse. Higher HRQoL was associated with higher educational attainment, being married, and having higher social support, while lower HRQoL was associated with being widowed, in worse financial situation, having chronic diseases and being in the oldest age groups. CONCLUSIONS: Findings show that gender, socioeconomic level, educational attainment, marital status as well as social support & community participation are relevant factors influencing HRQoL in our study sample. With respect to the SF-36 subscales, HRQoL of Jewish older adults in Mexico present higher scores than that of adults and older adults previously found in other studies in Mexico. Further studies comparing other characteristics among them could help bring further understanding of these differentiated ageing processes.

The dialectics of universality: The heterodox critical social theory of Robert Fine.

Robert Fine was among the most original social theorists in Britain of the past 30 years, and the aim of this paper is to offer a first systematic assessment of his intellectual contribution. There are sound intellectual reasons to explore Fine's scholarship. He maintained a problematic relation with mainstream sociology and, against the reduction of sociology to questions of method, culture, or class, he argued that sociologists must continue to ask difficult normative questions as part of the social world they ought to explain. And there are also pressing political concerns that justify a reconsideration of his writings. Global politics is currently marked by a populist wave that decries the very ideas and values that were central to Fine's social theory: the need to uphold the rule of law at home and abroad, the politics of cosmopolitan solidarity, and the significance of antisemitism and its relationships with different forms of authoritarian politics. My main argument is that there is a dialectics of universality that drives forward Fine's intellectual project. By this, I mean that a universalistic idea of humanity-an all-inclusive conception of all human beings-is the most important normative intuition of modern times. This idea of humanity moves forward in history through a dual process of emancipation and domination: successful forms of social, legal, and political inclusion help make visible previous dynamics of exclusion but may also create or recreate discriminatory practices. Building on the work of French historian Michael Löwy on heterodox Jewish thinkers, I explain the three main tenets of Fine's work: (a) his reconstruction of critical social theory; (b) the notion of cosmopolitan solidarity; and (c) the significance and main features of modern antisemitism.

Maternal Education Is Inversely Related to Vaccination Delay among Infants and Toddlers.

OBJECTIVE: To determine the association between parents' level of education and delay in vaccination among infants and toddlers. STUDY DESIGN: A case-control study done in 2015-2016. Charts of 2- to 4-year-old children vaccinated in 5 neighborhood Maternal-Child Health Centers (MCHCs) in southern Israel were examined for demographic variables. Five vaccination opportunities between age 7 months and 18 months were selected to test for delays. In each MCHC, children vaccinated at the longest time-period after planned vaccination dose (fifth quintile) were compared with those vaccinated during the middle quintile. Using this relative delay approach rather than absolute delay approach permitted us to adjust the findings to the prevailing environmental and to cultural and programmatic variations between the various neighborhoods. Each of the planned vaccination visits and overall, demographic and health behavior-related variables that were significantly associated to delays by univariate analysis were tested by multivariate analysis and further adjusted by using stepwise logistic regression, using goodness of fit measures. RESULTS: Data for 2072 subjects were collected (398-426 per MCHC). Fathers' education was not associated with delays. In contrast, mothers' education was inversely associated with the probability of vaccination delay by 4%-9% (depending on the vaccination visit) for each year of schooling beyond 10 years. CONCLUSION: Using the relative delay approach, we demonstrated that maternal education, measured by schooling years, was independently inversely associated with risk of vaccination delay. This suggests that education can be regarded as an important positive component of the overall disease prevention planning at national and global levels.

Depression and cancer were independently associated with quality of life in Brazilian older people.

OBJECTIVE: To analyse the factors associated with low health-related quality of life (HRQoL) in older people living in Brazil. METHODS: In this cross-sectional study of the Jewish community residing in Sao Paulo, Brazil, we extensively evaluated the characteristics - including clinical, functional and sociodemographic - of 496 older people. Quality of life was assessed using the World Health Organization Quality of Life-BREF (WHOQOL-BREF), while the Geriatric Depression Scale (GDS) was used to measure depressive symptoms. RESULTS: After adjusting for potential confounders, we found that GDS score (ß = -0.07; P = 0.04) and cancer (ß = -0.47; P = 0.05) were associated with a low WHOQOL-BREF score. CONCLUSION: Depressive symptoms and cancer were independently associated with low HRQoL among older people living in Brazil.

A visão ramazziniana e os discriminados / Ramazzini's views on discriminate-against people

No seu livro Doenças dos trabalhadores, publicado em 1700, Bernardino Ramazzini dedicou um capítulo às doenças que acometiam os judeus. Nessa época, eles eram frequentemente perseguidos e proibidos de exercer a maioria das ocupações, restando-lhes como principal atividade permitida a recuperação e o comércio de roupas a partir de tecidos velhos e usados. Ramazzini observou que problemas respiratórios, cutâneos e oculares eram comuns para esse povo e estavam relacionados a sua atividade ocupacional típica. Concluindo, a fé religiosa foi fator relevante para determinar a morbidade desse grupo populacional.

In his book Diseases of workers, published in 1700, Bernardino Ramazzini devoted a chapter to the diseases affecting Jews. At that time, Jews were often persecuted and forbidden to engage in most occupations, except for recovering and selling clothes made of old and worn cloth. Ramazzini noticed that respiratory, skin and eye problems were common among Jews, and were related to their typical occupations. To conclude, religion has been a relevant determinant of the morbidity of this population group.

Real-Life Glycemic Control in Children with Type 2 Diabetes: A Population-Based Study.

OBJECTIVES: To characterize children and adolescents with type 2 diabetes mellitus (T2DM) insured by a large health maintenance organization, and to identify variables associated with treatment quality and disease outcome. STUDY DESIGN: Children and adolescents diagnosed with T2DM over a 9-year period were identified from the database of Clalit Health Services, a large health maintenance organization in Israel (1 213 362 members aged 0-18 years). Demographic, anthropometric, clinical, and laboratory data were analyzed. RESULTS: A total of 96 patients (47 males) met our inclusion criteria. The mean age at diagnosis of T2DM was 14.25 ± 2.51 years. At the time of diagnosis, the median hemoglobin A1c (HbA1c) level was 7.8%, and additional components of the metabolic syndrome were present in 14.9%-67.4% of the patients. At the end of the follow-up period (3.11 ± 1.75 years), >50% of the patients were being treated with insulin; the median HbA1c value was 7.97%, and 44.6% of the patients achieved the target HbA1c of <7.0%. On multivariate linear regression analysis, the variables found to predict worse glycemic control (ie, higher HbA1c) were a higher HbA1c at diagnosis, a higher body mass index SD score at diagnosis, fewer annual HbA1c tests, and Arabic ethnicity [F(4,81) = 7.139; P < .001; R2 = 0.271]. CONCLUSION: This population-based study of pediatric patients with T2DM demonstrates that reasonable glycemic control can be achieved in both community and outpatient hospital settings. Nevertheless, there is room for improvement in intervention programs to optimize outcomes and decrease the risk of complications.

The origin of the p.E180 growth hormone receptor gene mutation.

Laron syndrome, an autosomal recessive condition of extreme short stature, is caused by the absence or dysfunction of the growth hormone receptor. A recurrent mutation in the GHR gene, p.E180, did not alter the encoded amino acid, but activated a cryptic splice acceptor resulting in a receptor protein with an 8-amino acid deletion in the extracellular domain. This mutation has been observed among Sephardic Jews and among individuals in Ecuador, Brazil and Chile, most notably in a large genetic isolate in Loja, Ecuador. A common origin has been postulated based on a shared genetic background of markers flanking this mutation, suggesting that the Lojanos (and others) may have Sephardic (Converso) Jewish ancestry. Analysis of the population structure of Lojanos based on genome-wide analysis demonstrated European, Sephardic Jewish and Native American ancestry in this group. X-autosomal comparison and monoallelic Y chromosomal and mitochondrial genetic analysis demonstrated gender-biased admixture between Native American women and European and Sephardic Jewish men. These findings are compatible with the co-occurrence of the Inquisition and the colonization of the Americas, including Converso Jews escaping the Inquisition in the Iberian Peninsula. Although not found among Lojanos, Converso Jews also brought founder mutations to contemporary Hispanic and Latino populations in the BRCA1 (c.68_69delAG) and BLM (c.2207_2212delATCTGAinsTAGATTC) genes.

La construcción de identidades judías LGBT a través de prácticas diaspóricas. Estudio sobre organizaciones judías LGBT en América Latina / A construção de identidades judias LGBT através de práticas diaspóricas. Estudo sobre organizações judias LGBT na América Latina / The construction of LGBT jewish identities through diasporic practices. A study on LGBT jewish organizations in Latin America

Resumen La investigación acerca de las identidades judías LGBT ha tendido a dar cuenta de la tensión entre ambas identidades. Esta tensión descansaría en que los propios textos religiosos del judaismo condenan las prácticas homosexuales. Sin embargo, se observa que algunas organizaciones judías LGBT construyen un discurso donde lo judío y la diversidad sexual se amalgaman. Esto ocurre porque, para estas organizaciones, el significado del judaísmo no descansa en lo religioso, sino que se construye a través de prácticas diaspóricas etno-políticas orientadas hacia la legitimación del Estado de Israel. El trabajo tiene como objetivo analizar la construcción de la amalgama entre judaísmo y diversidad sexual indagando en las prácticas diaspóricas de los actores sociales. Toma como caso de estudio las organizaciones JAG y Hod, de Argentina y Chile, respectivamente.

Resumo A investigação a respeito das identidades judias LGBT procurou dar conta da tensão entre ambas as identidades. Esta tensão se apoia nos mesmos textos religiosos que condenam as práticas homossexuais. Entretanto, observa-se que algumas organizações judias LGBT constroem um discurso em que o judeu e a diversidade sexual se amalgamam. Isto ocorre porque, para estas organizações, o significado do judaísmo não se apoia no religioso, mas sim se constrói através de práticas diaspóricas etnopolíticas orientadas para a legitimação do Estado de Israel. O trabalho tem como objetivo analisar a construção do amálgama entre judaísmo e diversidade sexual, indagando sobre as práticas diaspóricas dos atores sociais. Toma como caso de estudo as organizações JAG e Hod, da Argentina e do Chile, respectivamente.

Abstract Research on the construction of LGBT Jewish identities has revealed a conflict between both identities. This tension, is said, rests on the sacred texts of Judaism that condemn homosexuality. Nevertheless, some LGBT Jewish organizations construct a discourse in which Jewishness and sexual diversity are blended with each other. The conditions of possibility of this process rest in the fact that the discourse of these organizations is not based on religion, but on ethno-political diasporic practices aimed at legitimizing the State of Israel. The paper analyzes the merging of Judaism and sexual diversity looking at the diasporic practices of social actors. It looks at the cases of two Jewish LGBT organizationz: JAG, from Argentina, and Hod, from Chile.

Israeli Arabs develop diverticulitis at a younger age and are more likely to require surgery than Jews.

BACKGROUND: Only few studies have examined the impact of racial differences on the age of onset, course and outcomes of diverticulitis. AIM: To provide data about the epidemiology of diverticulitis in northern Israel, and to determine whether ethnicity is a predictor of age of onset, complications, and need for surgery. METHODS: Was conducted a retrospective review of the charts of all patients diagnosed with a first episode of diverticulitis in our hospital between 2005 and 2012. RESULTS: Were found 638 patients with a first episode of acute diverticulitis in the eight year interval. Israeli Arabs developed a first episode of diverticulitis at a younger age compared to Jews (51.2 vs 63.8 years, p<0.01). Arabs living in rural areas developed diverticulitis at a younger age than Arabs living in urban centers (49.4 vs 54.5 years, P=0.03). Jewish and Arabic men developed diverticulitis at younger age compared to their female counterparts (59.9 vs 66.09, p<0.01, and 47.31 vs 56.93, p<0.01, respectively). Arabs were more likely [odds ratio (OR)=1.81 ,95% confidence interval (CI)1.12-2.90, p=0.017] than Jews to require surgical treatment (urgent or elective) for diverticulitis. CONCLUSIONS: Israeli Arabs tend to develop diverticulitis at a younger age and are more likely to require surgical treatment for diverticulitis compared to Jews. Arabs living in rural areas develop diverticulitis at a younger age than Arabs living in urban centers. These findings highlight a need to address the root cause for ethnic differences in onset, course and outcome of acute diverticulitis.

Age-specific penetrance of LRRK2 G2019S in the Michael J. Fox Ashkenazi Jewish LRRK2 Consortium.

OBJECTIVE: Estimates of the penetrance of LRRK2 G2019S vary widely (24%-100%), reflective of differences in ascertainment, age, sex, ethnic group, and genetic and environmental modifiers. METHODS: The kin-cohort method was used to predict penetrance in 2,270 relatives of 474 Ashkenazi Jewish (AJ) Parkinson disease (PD) probands in the Michael J. Fox LRRK2 AJ Consortium in New York and Tel Aviv, Israel. Patients with PD were genotyped for the LRRK2 G2019S mutation and at least 7 founder GBA mutations. GBA mutation carriers were excluded. A validated family history interview, including age at onset of PD and current age or age at death for each first-degree relative, was administered. Neurologic examination and LRRK2 genotype of relatives were included when available. RESULTS: Risk of PD in relatives predicted to carry an LRRK2 G2019S mutation was 0.26 (95% confidence interval [CI] 0.18-0.36) to age 80 years, and was almost 3-fold higher than in relatives predicted to be noncarriers (hazard ratio [HR] 2.89, 95% CI 1.73-4.55, p < 0.001). The risk among predicted G2019S carrier male relatives (0.22, 95% CI 0.10-0.37) was similar to predicted carrier female relatives (0.29, 95% CI 0.18-0.40; HR male to female: 0.74, 95% CI 0.27-1.63, p = 0.44). In contrast, predicted noncarrier male relatives had a higher risk (0.15, 95% CI 0.11-0.20) than predicted noncarrier female relatives (0.07, 95% CI 0.04-0.10; HR male to female: 2.40, 95% CI 1.50-4.15, p < 0.001). CONCLUSION: Penetrance of LRRK2 G2019S in AJ is only 26% and lower than reported in other ethnic groups. Further study of the genetic and environmental risk factors that influence G2019S penetrance is warranted.

Israeli Arabs develop diverticulitis at a younger age and are more likely to require surgery than Jews / Árabes israelitas desenvolvem diverticulite em idade mais jovem e estão mais sujeitos ao tratamento cirúrgico do que os judeus

BACKGROUND: Only few studies have examined the impact of racial differences on the age of onset, course and outcomes of diverticulitis. AIM: To provide data about the epidemiology of diverticulitis in northern Israel, and to determine whether ethnicity is a predictor of age of onset, complications, and need for surgery. METHODS: Was conducted a retrospective review of the charts of all patients diagnosed with a first episode of diverticulitis in our hospital between 2005 and 2012. RESULTS: Were found 638 patients with a first episode of acute diverticulitis in the eight year interval. Israeli Arabs developed a first episode of diverticulitis at a younger age compared to Jews (51.2 vs 63.8 years, p<0.01). Arabs living in rural areas developed diverticulitis at a younger age than Arabs living in urban centers (49.4 vs 54.5 years, P=0.03). Jewish and Arabic men developed diverticulitis at younger age compared to their female counterparts (59.9 vs 66.09, p<0.01, and 47.31 vs 56.93, p<0.01, respectively). Arabs were more likely [odds ratio (OR)=1.81 ,95% confidence interval (CI)1.12-2.90, p=0.017] than Jews to require surgical treatment (urgent or elective) for diverticulitis. CONCLUSIONS: Israeli Arabs tend to develop diverticulitis at a younger age and are more likely to require surgical treatment for diverticulitis compared to Jews. Arabs living in rural areas develop diverticulitis at a younger age than Arabs living in urban centers. These findings highlight a need to address the root cause for ethnic differences in onset, course and outcome of acute diverticulitis. .

RACIONAL: Somente poucos estudos examinaram o impacto das diferenças raciais na idade de início, curso e os resultados da diverticulite. OBJETIVO: Fornecer dados sobre a epidemiologia da diverticulite no norte de Israel, e determinar se a etnia é preditor de idade de início, complicações e necessidade de tratamento cirúrgico. MÉTODOS: Foi realizado estudo retrospectivo dos prontuários de todos os pacientes diagnosticados com um primeiro episódio de diverticulite em nosso hospital entre 2005 e 2012. RESULTADOS: Foram encontrados 638 pacientes com um primeiro episódio de diverticulite aguda no intervalo de oito anos. Os árabes israelenses desenvolveram o primeiro episódio de diverticulite em idade mais jovem em comparação com os judeus (51,2 vs 63,8 anos, p<0,01). Árabes que vivem em áreas rurais a diverticulite foi desenvolvida em idade mais jovem do que os árabes que vivem em centros urbanos (49,4 vs 54,5 anos, p=0,03). Homens judeus e árabes desenvolveram diverticulite em idade mais jovem em comparação com os seus homólogos do sexo feminino (59,9 vs 66,09, p<0,01, e 47,31 vs 56,93, p<0,01, respectivamente). Os árabes eram mais prováveis ​​do que os judeus de necessitar de tratamento cirúrgico (urgência ou eletiva) para a diverticulite [odds ratio (OR)=1,81, intervalo de confiança de 95% (CI) 1,12-2,90, p=0,017]. CONCLUSÕES: Os árabes israelenses tendem a desenvolver diverticulite em idade mais jovem e são mais propensos a necessitar de tratamento cirúrgico para a diverticulite em comparação com os judeus. Árabes que vivem em áreas rurais desenvolvem diverticulite em idade mais jovem do que os árabes que vivem em centros urbanos. Estes resultados destacam a necessidade de abordar a causa raiz para diferenças étnicas em início, o curso e o resultado da diverticulite aguda. .