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1.
Head Neck Pathol ; 14(3): 842-846, 2020 Sep.
Article in English | MEDLINE | ID: mdl-31782116

ABSTRACT

Juvenile mandibular chronic osteomyelitis (JMCO) is a rare, idiopathic disease of chronic bone inflammation without suppuration, sinus tract formation, or sequestration. As the name suggests, this condition predominately affects children. The few cases of JMCO reported in the literature describe different treatments, and thus a standard therapy protocol has not yet been established. The aim of this paper is to report a clinical case in a 9-year-old girl that was misdiagnosed and unsuccessfully treated for 1 year. After experiencing persistent symptoms, a correct diagnosis was subsequently rendered based on the physical and radiographic examination as well as successful treatment with non-steroidal anti-inflammatory drugs (NSAIDs). The patient received drug therapy followed by periods of remission over a 4 year follow-up period. Diagnosis and treatment of JMCO is a challenge given the rarity and nonspecific signs and symptoms of this condition. Treatment with NSAIDs and regular follow-up is a conservative option for these patients.


Subject(s)
Anti-Inflammatory Agents, Non-Steroidal/therapeutic use , Indomethacin/therapeutic use , Mandibular Diseases/diagnosis , Osteomyelitis/diagnosis , Anti-Bacterial Agents/therapeutic use , Child , Cytomegalovirus Infections/diagnosis , Cytomegalovirus Infections/drug therapy , Diagnostic Errors , Female , Humans , Mandibular Diseases/drug therapy , Mumps/diagnosis , Mumps/drug therapy , Osteomyelitis/drug therapy , Parotitis/diagnosis , Parotitis/drug therapy
2.
Rev. costarric. salud pública ; 27(1): 79-86, ene.-jun. 2018.
Article in Spanish | LILACS | ID: biblio-960277

ABSTRACT

Resumen En la presente revisión se ofrecen las pautas éticas que rigen el esquema con que debe ser aplicada la vacuna triple contra Sarampión Rubeola y Paperas. Se hace énfasis en la falta de datos clínicos que hayan asociado esta vacuna con el desarrollo de autismo en niños y se expone con base en evidencia científica los riesgos de la no vacunación en este grupo etario.


Abstract In the present review is offered the ethical guidelines that govern the scheme with which the triple vaccine against Measles Rubella and Mumps must to be applied. It emphasizes the lack of clinical data that have associated this vaccine with the development of autism in children and exposes based on scientific evidence the risks of non-vaccination in this age group.


Subject(s)
Rubella/drug therapy , Autistic Disorder , Vaccination/adverse effects , Measles-Mumps-Rubella Vaccine/analysis , Measles/drug therapy , Mumps/drug therapy , Rubella Syndrome, Congenital , Immunization Programs , Costa Rica
3.
Arq. bras. med ; 60(4): 331-5, jul.-ago. 1986. tab, ilus
Article in Portuguese | LILACS | ID: lil-34677

ABSTRACT

Em estudo clínico duplo-cego, randomizado versus placebo durante 7 dias, o diclofenaco resinato foi utilizado no tratamento sintomatológico da parotidite epidêmica em 60 pacientes. O grupo tratado com diclofenaco resinato (N=30) apresentou melhores resultados que o tratado com placebo (N=30) em relaçäo ao índice de desaparecimento dos sintomas: febre (p<0,0004), dor local (p<0,001) e disfagia (p<0,001), melhora do grau de edema local (p<0,001) e avaliaçäo global da eficácia terapêutica (p<0,001) na opiniäo do investigador. A incidência de efeitos colaterais observados foi bastante reduzida (6,6%) e avaliaçäo global na tolerabilidade foi considerada excelente ou boa nos dois grupos terapêuticos. Conclui-se, portanto, que o diclofenaco resinato contribui significativamente para a boa evoluçäo da sintomatologia dos pacientes portadores de parotidite epidêmica


Subject(s)
Infant , Child, Preschool , Child , Humans , Diclofenac/therapeutic use , Mumps/drug therapy , Placebos/therapeutic use , Clinical Trials as Topic , Double-Blind Method
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