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Childs Nerv Syst ; 22(3): 234-42, 2006 Mar.
Article in English | MEDLINE | ID: mdl-15937687

ABSTRACT

BACKGROUND: Cystic dysraphic lesions of the cervical and upper thoracic region are rare and only a few series have been published about the topic. These malformations can be divided into categories that include both myelocystoceles and the so-called cervical meningoceles or myelomeningoceles. METHODS: A retrospective study of 18 patients was conducted. RESULTS: In 17 patients a squamous or a cicatricial epithelium of variable thickness covered the dome of the lesions, while the base was covered with full-thickness skin. In one case the skin was entirely normal. Four patients displayed associated CNS malformations and three more had systemic congenital anomalies. All patients underwent surgical exploration and the length of time between birth and surgery ranged from 6 h to 9 months. The most frequent surgical finding, seen in 14 patients, was a stalk connecting the dorsal surface of the spinal cord to the cyst. In three patients the findings were consistent with myelocystocele. Only in one case was a true meningocele found. Hydrocephalus and Chiari II malformation were not as consistently associated as in myelomeningoceles. Neurological signs and symptoms were not so marked as in myelomeningoceles and were found in the follow-up of four patients. In two of them there was a non-progressive deficit, probably expressing an imperceptible involvement of the nervous system in the first year of life. The histopathological findings were of three types: neuroglial stalks, fibrovascular stalks and myelocystoceles. CONCLUSIONS: Cystic dysraphisms of the cervical and upper thoracic region differ clinically and structurally from meningomyelocele and have a more favorable outcome. We believe that these malformations have not been properly labeled and propose a classification based on the structures found inside the cyst.


Subject(s)
Cervical Vertebrae/abnormalities , Spina Bifida Cystica/pathology , Thoracic Vertebrae/abnormalities , Ultrasonography, Prenatal , Abnormalities, Multiple , Cervical Vertebrae/diagnostic imaging , Cervical Vertebrae/surgery , Female , Follow-Up Studies , Humans , Infant , Infant, Newborn , Male , Meningomyelocele/diagnostic imaging , Meningomyelocele/pathology , Meningomyelocele/surgery , Retrospective Studies , Spina Bifida Cystica/classification , Spina Bifida Cystica/diagnostic imaging , Spina Bifida Cystica/surgery , Thoracic Vertebrae/diagnostic imaging , Thoracic Vertebrae/surgery , Treatment Outcome
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