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2.
BMJ Case Rep ; 17(6)2024 Jun 04.
Article En | MEDLINE | ID: mdl-38834313

Congenital subglottic stenosis is a rare but potentially catastrophic condition. In this report, we describe the management of a term neonate who was noted to have biphasic stridor during preassessment for correction of an imperforate anus at 26 hours of life. The neonate was found to have a pinhole trachea secondary to congenital subglottic stenosis. It was impossible to pass an endotracheal tube, so the neonate underwent an emergency surgical tracheostomy with a good outcome. A high index of suspicion led to appropriate steps being taken to safely anaesthetise the neonate.


Laryngostenosis , Respiratory Sounds , Tracheostomy , Humans , Infant, Newborn , Respiratory Sounds/etiology , Laryngostenosis/surgery , Trachea/surgery , Trachea/abnormalities , Male , Intubation, Intratracheal/methods
5.
World J Gastroenterol ; 30(16): 2272-2280, 2024 Apr 28.
Article En | MEDLINE | ID: mdl-38690021

BACKGROUND: The magnetic compression technique has been used to establish an animal model of tracheoesophageal fistula (TEF), but the commonly shaped magnets present limitations of poor homogeneity of TEF and poor model control. We designed a T-shaped magnet system to overcome these problems and verified its effectiveness via animal experiments. AIM: To investigate the effectiveness of a T-shaped magnet system for establishing a TEF model in beagle dogs. METHODS: Twelve beagles were randomly assigned to groups in which magnets of the T-shaped scheme (study group, n = 6) or normal magnets (control group, n = 6) were implanted into the trachea and esophagus separately under gastroscopy. Operation time, operation success rate, and accidental injury were recorded. After operation, the presence and timing of cough and the time of magnet shedding were observed. Dogs in the control group were euthanized after X-ray and gastroscopy to confirm establishment of TEFs after coughing, and gross specimens of TEFs were obtained. Dogs in the study group were euthanized after X-ray and gastroscopy 2 wk after surgery, and gross specimens were obtained. Fistula size was measured in all animals, and then harvested fistula specimens were examined by hematoxylin and eosin (HE) and Masson trichrome staining. RESULTS: The operation success rate was 100% for both groups. Operation time did not differ between the study group (5.25 min ± 1.29 min) and the control group (4.75 min ± 1.70 min; P = 0.331). No bleeding, perforation, or unplanned magnet attraction occurred in any animal during the operation. In the early postoperative period, all dogs ate freely and were generally in good condition. Dogs in the control group had severe cough after drinking water at 6-9 d after surgery. X-ray indicated that the magnets had entered the stomach, and gastroscopy showed TEF formation. Gross specimens of TEFs from the control group showed the formation of fistulas with a diameter of 4.94 mm ± 1.29 mm (range, 3.52-6.56 mm). HE and Masson trichrome staining showed scar tissue formation and hierarchical structural disorder at the fistulas. Dogs in the study group did not exhibit obvious coughing after surgery. X-ray examination 2 wk after surgery indicated fixed magnet positioning, and gastroscopy showed no change in magnet positioning. The magnets were removed using a snare under endoscopy, and TEF was observed. Gross specimens showed well-formed fistulas with a diameter of 6.11 mm ± 0.16 mm (range, 5.92-6.36 mm), which exceeded that in the control group (P < 0.001). Scar formation was observed on the internal surface of fistulas by HE and Masson trichrome staining, and the structure was more regular than that in the control group. CONCLUSION: Use of the modified T-shaped magnet scheme is safe and feasible for establishing TEF and can achieve a more stable and uniform fistula size compared with ordinary magnets. Most importantly, this model offers better controllability, which improves the flexibility of follow-up studies.


Disease Models, Animal , Magnets , Trachea , Tracheoesophageal Fistula , Animals , Dogs , Tracheoesophageal Fistula/surgery , Tracheoesophageal Fistula/pathology , Tracheoesophageal Fistula/etiology , Trachea/surgery , Trachea/pathology , Esophagus/surgery , Esophagus/pathology , Esophagus/diagnostic imaging , Gastroscopy/instrumentation , Gastroscopy/methods , Operative Time , Male , Magnetics/instrumentation , Equipment Design , Humans
7.
Laryngorhinootologie ; 103(S 01): S148-S166, 2024 May.
Article En, De | MEDLINE | ID: mdl-38697146

The laryngotracheal junction is an anatomical region with special pathophysiological features. This review presents clinical pictures and malformations that manifest pre-dilectively at this localisation in children and adolescents as well as in adults. The diagnostic procedure is discussed. The possibilities of surgical reconstruction are presented depending on the pathology and age of the patient.


Larynx , Plastic Surgery Procedures , Trachea , Humans , Trachea/surgery , Trachea/abnormalities , Larynx/surgery , Larynx/abnormalities , Adolescent , Child , Plastic Surgery Procedures/methods , Adult , Laryngostenosis/surgery
8.
BMJ Case Rep ; 17(5)2024 May 13.
Article En | MEDLINE | ID: mdl-38740444

With the advancements in the medical field, many innovations in medical devices have happened. Using a surgical stapler to close the laryngectomy defect without opening the pharynx is particularly advantageous in a total laryngectomy (TL). However, performing the tracheoesophageal puncture (TEP) during stapler closure of the larynx has not been widely advocated, due to the fear of complications related to the procedure.We treated two male patients with advanced glottic malignancy who underwent a TL. To restore their ability to speak, we performed a primary TEP and immediate voice prosthesis placement. After the TEP, we closed the larynx using a stapler. The surgical technique used in this procedure has been thoroughly explained.The use of a surgical stapler for pharyngeal closure during a TL has several advantages, particularly with regard to the duration of surgery. The current techniques appear to be promising in reducing TEP-related complications during stapler-assisted laryngeal closure.


Laryngeal Neoplasms , Laryngectomy , Punctures , Trachea , Humans , Male , Laryngectomy/methods , Laryngectomy/adverse effects , Laryngeal Neoplasms/surgery , Punctures/methods , Trachea/surgery , Esophagus/surgery , Surgical Staplers , Aged , Middle Aged , Larynx/surgery , Surgical Stapling/methods , Larynx, Artificial
9.
BMJ Case Rep ; 17(5)2024 May 28.
Article En | MEDLINE | ID: mdl-38806399

Increasing use of tracheal expandable metallic hybrid stents will lead to common encounters with these devices in emergency airway management. The presence of these stents qualifies any patient as a challenge when an emergency tracheostomy is needed. We report an unorthodox technique of tracheostomy with concomitant removal of tracheal stent, without any major complications. Although the combined approach with bronchoscopy and tracheostomy has been reported in similar cases, we present a safe procedure when rigid bronchoscopy is not available.


Bronchoscopy , Device Removal , Tracheostomy , Humans , Tracheostomy/adverse effects , Tracheostomy/instrumentation , Tracheostomy/methods , Device Removal/methods , Bronchoscopy/methods , Stents/adverse effects , Trachea/surgery , Male , Tracheal Stenosis/surgery , Tracheal Stenosis/therapy , Tracheal Stenosis/etiology , Female
10.
Sci Rep ; 14(1): 11457, 2024 05 20.
Article En | MEDLINE | ID: mdl-38769365

To compare two different wavelengths of the surgical contact diode laser (CDL) for producing a posterior laryngofissure in in-vivo pigs. Anesthetized pigs underwent a tracheostomy and an anterior laryngofissure through a cervicotomy. They were randomly selected for the CDL wavelength and Power, according to the peak of Power set at device (980nm wavelength: Ppeak power of 10 W, 15 W, and 20 W, or 1470 nm wavelength: Ppeak 3 W, 5 W, 7 W, 10 W). At the end of the experiment, the laryngotracheal specimen was extracted and sent for histology and morphometry measurements (incision size, depth, area, and lateral thermal damage). Hemodynamic data and arterial blood gases were recorded during the incisions. Statistical analysis of the comparisons between the parameters and groups had a level of significance of p < 0.05. Twenty-six pigs were divided into CDL 980 nm (n = 11) and 1470 nm (n = 15). There was a greater incision area at the thyroid level in the 980 nm CDL and a wider incision at the trachea level, with a larger distance between mucosa borders. There were no significant differences in the area of lateral thermal damage between the two groups and neither difference among the power levels tested. Both wavelengths tested showed similar results in the various combinations of power levels without significant differences in the lateral thermal damage. The posterior laryngofissure incision can be performed by either of the wavelengths at low and medium power levels without great difference on lateral thermal damage.


Larynx , Lasers, Semiconductor , Animals , Swine , Larynx/surgery , Laser Therapy/methods , Trachea/surgery
11.
J Craniofac Surg ; 35(4): e399-e401, 2024 Jun 01.
Article En | MEDLINE | ID: mdl-38722317

VACTERL association is diagnosed based on the non-random co-occurrence of at least 3 out of 6 congenital malformations. The prevalence is thought to be less than 1 in 10,000 to 1 in 40,000. There is no known link between VACTERL association and metopic synostosis in the literature. There were 122 operated cases of metopic synostosis at our institution from 1999 to 2023, with a 2.3:1 male-to-female ratio. The authors describe the co-occurrence of VACTERL association and metopic synostosis in 3 female patients with no identifiable genetic variants. Given that VACTERL association is a diagnosis of exclusion, other rare syndromes were considered but ultimately excluded. This suggests that the co-occurrence of VACTERL association and metopic synostosis is a potentially rare finding, and underlying pathogenic variants are yet to be identified.


Anal Canal , Craniosynostoses , Esophagus , Heart Defects, Congenital , Limb Deformities, Congenital , Trachea , Humans , Female , Craniosynostoses/genetics , Craniosynostoses/surgery , Craniosynostoses/complications , Limb Deformities, Congenital/genetics , Trachea/abnormalities , Trachea/surgery , Heart Defects, Congenital/surgery , Anal Canal/abnormalities , Anal Canal/surgery , Infant , Esophagus/abnormalities , Esophagus/surgery , Spine/abnormalities , Male , Kidney/abnormalities
12.
Head Neck ; 46(7): 1835-1840, 2024 Jul.
Article En | MEDLINE | ID: mdl-38711230

The internal mammary artery perforator (IMAP) flap is an evolution of the deltopectoral flap that is harvested based upon a single perforator from the internal mammary artery. Its favorable characteristics include pliability as a fasciocutaneous flap, ease of harvest, and minimal donor site morbidity. In this paper, we report our harvest technique and the versatility of the IMAP flap for pharyngoesophageal, cervical tracheal, and cutaneous neck defects. We seek to highlight the IMAP as a useful regional reconstructive option in both the primary and salvage reconstructive setting. As such, this flap is an important option in the head and neck reconstructive surgeon's armamentarium.


Mammary Arteries , Perforator Flap , Plastic Surgery Procedures , Humans , Perforator Flap/blood supply , Mammary Arteries/surgery , Mammary Arteries/transplantation , Plastic Surgery Procedures/methods , Trachea/surgery , Neck/surgery , Male , Middle Aged , Pharynx/surgery , Head and Neck Neoplasms/surgery , Female , Pharyngeal Neoplasms/surgery , Skin Transplantation/methods , Aged
13.
BMC Pulm Med ; 24(1): 238, 2024 May 15.
Article En | MEDLINE | ID: mdl-38750487

BACKGROUND: Biodegradable (BD) stents made from polydioxanone have been used only in human airways. These stents combine the advantages of classical tracheal stents, and fewer side effects are expected due to their biocompatibility and their time-limited presence in airways. However, new clinical consequences have arisen. Here, the authors share their experiences with BD stents for tracheal indications, focusing on their safety and efficacy. METHODS: This was a retrospective review of a collected database of adult patients who underwent implantation of biodegradable tracheal stents between September 2013 and December 2022 at the Department of Respiratory Medicine of the 1st Faculty of Medicine in Prague and Thomayer University Hospital. The indications included functionally significant nonmalignant tracheal stenosis and tracheomalacia. Self-expandable, biodegradable, polydioxanone tracheal stents manufactured by ELLA-CS Ltd. (Hradec Kralove, Czech Republic) were implanted during rigid bronchoscopy under general anaesthesia. All patients were followed up in the department and were provided with the necessary care. The main efficacy and safety parameters and relationships were analysed using descriptive statistics and Fisher´s exact, Wilcoxon and Kruskal‒Wallis tests. RESULTS: A total of 65 stents were implanted in 47 adult patients. During the first two months after implantation, when adequate function was expected, the stent was found to be effective in 26 out of 39 patients who completed this period (66.7%). The clinical effectiveness reached 89.7%, as early restenoses were mostly mild and necessitated treatment in only 4 patients. The frequencies of significant mucostasis, migration and granulation tissue growth were 2.6%, 7.5% and 23.1%, respectively, during this period. Thirty-four participants completed the half-year follow-up period after the first or second stent insertion, and some were followed up beyond this period. Poor control of symptoms, the development of restenosis and the need for interventions were characteristic of this period as the stents degraded. Twenty-two patients who experienced remodelling or stabilization of the tracheal lumen achieved a stent-free state. Seven patients underwent subsequent surgical treatment. CONCLUSIONS: BD stents are safe and provide adequate tracheal support until they begin to degrade. The use of BD stents necessitates close monitoring of patients and accurate treatment of possible restenosis. TRIAL REGISTRATION: Based on project NT14146 - Biodegradable stents in the management of the large airways (2013-2015, MZ0/NT), registered on May 1, 2013, in the Research and Development and Innovation Information System of the Czech Republic and at ClinicalTrials.gov (reg. no. NCT02620319, December 2, 2015).


Absorbable Implants , Bronchoscopy , Stents , Tracheal Stenosis , Humans , Middle Aged , Male , Female , Retrospective Studies , Adult , Tracheal Stenosis/surgery , Aged , Polydioxanone , Tracheomalacia/surgery , Czech Republic , Treatment Outcome , Trachea/surgery , Prosthesis Design , Young Adult
15.
Einstein (Sao Paulo) ; 22: eRC0659, 2024.
Article En | MEDLINE | ID: mdl-38695416

A female newborn presented with respiratory distress at birth and was diagnosed with congenital tracheal stenosis. The stenosis was positioned at the distal trachea and compromised the carina and the right and left bronchi. She underwent surgical treatment using circulatory life support with veno-arterial peripheral extracorporeal membrane oxygenation, and the airway was reconstructed using the slide tracheoplasty technique to build a neocarina. The patient had an excellent postoperative course, was successfully weaned from extracorporeal membrane oxygenation and invasive ventilation, and was discharged.


Bronchi , Extracorporeal Membrane Oxygenation , Plastic Surgery Procedures , Trachea , Tracheal Stenosis , Humans , Female , Tracheal Stenosis/surgery , Tracheal Stenosis/congenital , Tracheal Stenosis/diagnostic imaging , Infant, Newborn , Trachea/surgery , Trachea/abnormalities , Trachea/diagnostic imaging , Extracorporeal Membrane Oxygenation/methods , Bronchi/surgery , Bronchi/abnormalities , Bronchi/diagnostic imaging , Plastic Surgery Procedures/methods , Treatment Outcome
16.
BMJ Case Rep ; 17(4)2024 Apr 09.
Article En | MEDLINE | ID: mdl-38594197

Primary tracheal schwannomas are rare benign tumours. This is a case report, and therefore, no specific methods or results are applicable. We here report a case of a tracheal schwannoma in an early adolescent girl presenting with subcutaneous emphysema and symptoms of airway obstruction. Tracheal resection and reconstruction by primary anastomosis were performed. Pathology confirmed the diagnosis of tracheal schwannoma. This is an unusual life-threatening presentation of a benign rare tracheal tumour with a challenging approach to management.


Mediastinal Emphysema , Neurilemmoma , Subcutaneous Emphysema , Tracheal Neoplasms , Female , Humans , Adolescent , Mediastinal Emphysema/diagnostic imaging , Mediastinal Emphysema/etiology , Mediastinal Emphysema/surgery , Trachea/diagnostic imaging , Trachea/surgery , Trachea/pathology , Tracheal Neoplasms/diagnosis , Tracheal Neoplasms/diagnostic imaging , Neurilemmoma/diagnosis , Neurilemmoma/diagnostic imaging , Subcutaneous Emphysema/diagnostic imaging , Subcutaneous Emphysema/etiology
18.
Eur J Cardiothorac Surg ; 65(5)2024 May 03.
Article En | MEDLINE | ID: mdl-38637945

OBJECTIVES: Surgical treatment for airway stenosis necessitates personalized techniques based on the stenosis location and length, leading to favourable surgical outcomes. However, there is limited literature on functional outcomes following laryngotracheal surgery with an adequate number of patients. METHODS: We conducted a retrospective analysis of patients who underwent laryngotracheal surgery at the Department of Thoracic Surgery, Medical University of Vienna, from January 2017 to June 2021. The study included standardized functional assessments before and after surgery, encompassing spirometry, voice measurements, swallowing evaluation and subjective patient perception. RESULTS: The study comprised 45 patients with an average age of 51.9 ± 15.9 years, of whom 89% were female, with idiopathic being the most common aetiology (67%). Procedures included standard cricotracheal resection in 11%, cricotracheal resection with dorsal mucosal flap in 49%, cricotracheal resection with dorsal mucosal flap and lateral cricoplasty in 24% and single-stage laryngotracheal reconstruction in 16%. There were no in-hospital mortalities or restenosis cases during the mean follow-up period of 20.8 ± 13.2 months. Swallowing function remained intact in all patients. Voice evaluations showed a decrease in fundamental vocal pitch [203 (81-290) Hz vs 150 (73-364) Hz, P < 0.001] and dynamic voice range (23.5 ± 5.8 semitones vs 17.8 ± 6.7 semitones, P < 0.001). However, no differences in voice volume were observed (60.0 ± 4.1 dB vs 60.2 ± 4.8 dB, P = 0.788). The overall predicted voice profile changed from R0B0H0 to R1B0H1. CONCLUSIONS: Laryngotracheal surgery proves effective in fully restoring breathing capacity while preserving vocal function. Even in cases of high-grade and complex airway stenosis necessitating laryngotracheal reconstruction, favourable functional outcomes can be achieved.


Laryngostenosis , Tracheal Stenosis , Humans , Female , Middle Aged , Male , Retrospective Studies , Laryngostenosis/surgery , Tracheal Stenosis/surgery , Adult , Treatment Outcome , Aged , Trachea/surgery , Larynx/surgery , Plastic Surgery Procedures/methods , Deglutition/physiology , Postoperative Period
19.
Artif Organs ; 48(6): 575-576, 2024 Jun.
Article En | MEDLINE | ID: mdl-38646888

South Korean-based team is first to successfully transplant 3D bioprinted artificial trachea. The success arises during scrutiny of artificial tracheal implants stemming from the denounced work of Dr. Paolo Macchiarini.


Trachea , Humans , Trachea/transplantation , Trachea/surgery , Printing, Three-Dimensional , Artificial Organs , Republic of Korea , Tissue Engineering/methods , Bioprinting/methods
20.
Kyobu Geka ; 77(4): 250-255, 2024 Apr.
Article Ja | MEDLINE | ID: mdl-38644170

BACKGROUND: Tracheobronchial injuries resulting from blunt trauma are relatively rare among chest injuries. However, if these injuries are not managed properly, they can be fatal. The prognosis is intricately linked to the precise diagnosis and treatment. We herein report three cases of tracheobronchial trauma that required surgical intervention. Case 1:A 17-year-old male sustained injuries when his torso became entangled in heavy machinery. The diagnosis revealed a tear in the right main bronchus, which required transportation with left single- lung ventilation. The patient was treated by tracheobronchial reconstruction. Case 2:A 71-year-old male experienced trauma when his car collided with a utility pole. He was transported to the hospital after tracheal intubation due to a laceration of the tracheal membranous area. The site of the injury was closed with sutures. Case 3:A 17-year-old female who had been struck by a train suffered acute respiratory failure and was transported to the hospital after intubation. Veno-venous extracorporeal membrane oxgenation (VV-ECMO) was initiated in response to poor oxygenation. Complete rupture of the right middle bronchial trunk and laceration of the right main bronchial membrane were observed, and bronchoplasty was performed. CONCLUSION: A swift and accurate diagnosis, coupled with timely and judicious therapeutic interventions, play a pivotal role in managing tracheal and bronchial injuries.


Bronchi , Trachea , Humans , Male , Adolescent , Trachea/injuries , Trachea/surgery , Bronchi/injuries , Bronchi/surgery , Female , Aged , Wounds, Nonpenetrating/surgery , Wounds, Nonpenetrating/complications , Wounds, Nonpenetrating/therapy , Thoracic Injuries/surgery , Thoracic Injuries/complications
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