ABSTRACT
Background: Soil water content is one of the critical indicators in agricultural systems. Visible/near-infrared hyperspectral remote sensing is an effective method for soil water estimation. However, noise removal from massive spectral datasets and effective feature extraction are challenges for achieving accurate soil water estimation using this technology. Methods: This study proposes a method for hyperspectral remote sensing soil water content estimation based on a combination of continuous wavelet transform (CWT) and competitive adaptive reweighted sampling (CARS). Hyperspectral data were collected from soil samples with different water contents prepared in the laboratory. CWT, with two wavelet basis functions (mexh and gaus2), was used to pre-process the hyperspectral reflectance to eliminate noise interference. The correlation analysis was conducted between soil water content and wavelet coefficients at ten scales. The feature variables were extracted from these wavelet coefficients using the CARS method and used as input variables to build linear and non-linear models, specifically partial least squares (PLSR) and extreme learning machine (ELM), to estimate soil water content. Results: The results showed that the correlation between wavelet coefficients and soil water content decreased as the decomposition scale increased. The corresponding bands of the extracted wavelet coefficients were mainly distributed in the near-infrared region. The non-linear model (ELM) was superior to the linear method (PLSR). ELM demonstrated satisfactory accuracy based on the feature wavelet coefficients of CWT with the mexh wavelet basis function at a decomposition scale of 1 (CWT(mexh_1)), with R2, RMSE, and RPD values of 0.946, 1.408%, and 3.759 in the validation dataset, respectively. Overall, the CWT(mexh_1)-CARS-ELM systematic modeling method was feasible and reliable for estimating the water content of sandy clay loam.
Subject(s)
Machine Learning , Soil , Water , Wavelet Analysis , Soil/chemistry , Water/analysis , Water/chemistry , Remote Sensing Technology/methods , Remote Sensing Technology/instrumentation , Spectroscopy, Near-Infrared/methods , Spectroscopy, Near-Infrared/instrumentation , Least-Squares Analysis , Environmental Monitoring/methods , Environmental Monitoring/instrumentationABSTRACT
The access of new energy improves the flexibility of distribution network operation, but also leads to more complex mechanism of line loss. Therefore, starting from the nonlinear, fluctuating and multi-scale characteristics of line loss data, and based on the idea of decomposition prediction, this paper proposes a new method of line loss frequency division prediction based on wavelet transform and BIGRU-LSTM (Bidirectional Gated Recurrent Unit-Long Short Term Memory Network).Firstly, the grey relation analysis and the improved NARMA (Nonlinear Autoregressive Moving Average) correlation analysis method are used to extract the non-temporal and temporal influencing factors of line loss, and the corresponding feature data set is constructed. Then, the historical line loss data is decomposed into physical signals of different frequency bands by using wavelet transform, and the multi-dimensional input data of the prediction network is formed with the above characteristic data set. Finally, the BIGRU-LSTM prediction network is built to realize the probabilistic prediction of high-frequency and low-frequency components of line loss. The effectiveness and applicability of the method proposed in this paper were verified through numerical simulation. By dividing the line loss data into different frequency bands for frequency prediction, the mapping relationship between different line loss components and influencing factors was accurately matched, thereby improving the prediction accuracy.
Subject(s)
Neural Networks, Computer , Wavelet Analysis , AlgorithmsABSTRACT
Autism spectrum disorder stands as a multifaceted and heterogeneous neurodevelopmental condition. The utilization of functional magnetic resonance imaging to construct functional brain networks proves instrumental in comprehending the intricate interplay between brain activity and autism spectrum disorder, thereby elucidating the underlying pathogenesis at the cerebral level. Traditional functional brain networks, however, typically confine their examination to connectivity effects within a specific frequency band, disregarding potential connections among brain areas that span different frequency bands. To harness the full potential of interregional connections across diverse frequency bands within the brain, our study endeavors to develop a novel multi-frequency analysis method for constructing a comprehensive functional brain networks that incorporates multiple frequencies. Specifically, our approach involves the initial decomposition of functional magnetic resonance imaging into distinct frequency bands through wavelet transform. Subsequently, Pearson correlation is employed to generate corresponding functional brain networks and kernel for each frequency band. Finally, the classification was performed by a multi-kernel support vector machine, to preserve the connectivity effects within each band and the connectivity patterns shared among the different bands. Our proposed multi-frequency functional brain networks method yielded notable results, achieving an accuracy of 89.1%, a sensitivity of 86.67%, and an area under the curve of 0.942 in a publicly available autism spectrum disorder dataset.
Subject(s)
Autism Spectrum Disorder , Brain , Connectome , Magnetic Resonance Imaging , Humans , Autism Spectrum Disorder/physiopathology , Autism Spectrum Disorder/diagnostic imaging , Connectome/methods , Magnetic Resonance Imaging/methods , Brain/diagnostic imaging , Brain/physiopathology , Male , Support Vector Machine , Female , Neural Pathways/physiopathology , Neural Pathways/diagnostic imaging , Young Adult , Nerve Net/diagnostic imaging , Nerve Net/physiopathology , Wavelet Analysis , Adult , AdolescentABSTRACT
BACKGROUND: Antioxidant proteins are involved in several biological processes and can protect DNA and cells from the damage of free radicals. These proteins regulate the body's oxidative stress and perform a significant role in many antioxidant-based drugs. The current invitro-based medications are costly, time-consuming, and unable to efficiently screen and identify the targeted motif of antioxidant proteins. METHODS: In this model, we proposed an accurate prediction method to discriminate antioxidant proteins namely StackedEnC-AOP. The training sequences are formulation encoded via incorporating a discrete wavelet transform (DWT) into the evolutionary matrix to decompose the PSSM-based images via two levels of DWT to form a Pseudo position-specific scoring matrix (PsePSSM-DWT) based embedded vector. Additionally, the Evolutionary difference formula and composite physiochemical properties methods are also employed to collect the structural and sequential descriptors. Then the combined vector of sequential features, evolutionary descriptors, and physiochemical properties is produced to cover the flaws of individual encoding schemes. To reduce the computational cost of the combined features vector, the optimal features are chosen using Minimum redundancy and maximum relevance (mRMR). The optimal feature vector is trained using a stacking-based ensemble meta-model. RESULTS: Our developed StackedEnC-AOP method reported a prediction accuracy of 98.40% and an AUC of 0.99 via training sequences. To evaluate model validation, the StackedEnC-AOP training model using an independent set achieved an accuracy of 96.92% and an AUC of 0.98. CONCLUSION: Our proposed StackedEnC-AOP strategy performed significantly better than current computational models with a ~ 5% and ~ 3% improved accuracy via training and independent sets, respectively. The efficacy and consistency of our proposed StackedEnC-AOP make it a valuable tool for data scientists and can execute a key role in research academia and drug design.
Subject(s)
Antioxidants , Proteins , Antioxidants/chemistry , Proteins/chemistry , Proteins/metabolism , Computational Biology/methods , Machine Learning , Algorithms , Wavelet Analysis , Support Vector Machine , Databases, Protein , Position-Specific Scoring MatricesABSTRACT
Atrial fibrillation (AF) is the most prevalent form of arrhythmia, with a rising incidence and prevalence worldwide, posing significant implications for public health. In this paper, we introduce an approach that combines the Recurrence Plot (RP) technique and the ResNet architecture to predict AF. Our method involves three main steps: using wavelet filtering to remove noise interference; generating RPs through phase space reconstruction; and employing a multi-level chained residual network for AF prediction. To validate our approach, we established a comprehensive database consisting of electrocardiogram (ECG) recordings from 1008 AF patients and 48,292 Non-AF patients, with a total of 2067 and 93,129 ECGs, respectively. The experimental results demonstrated high levels of prediction precision (90.5%), recall (89.1%), F1 score (89.8%), accuracy (93.4%), and AUC (96%) on our dataset. Moreover, when tested on a publicly available AF dataset (AFPDB), our method achieved even higher prediction precision (94.8%), recall (99.4%), F1 score (97.0%), accuracy (97.0%), and AUC (99.7%). These findings suggest that our proposed method can effectively extract subtle information from ECG signals, leading to highly accurate AF predictions.
Subject(s)
Atrial Fibrillation , Electrocardiography , Atrial Fibrillation/physiopathology , Atrial Fibrillation/diagnosis , Humans , Electrocardiography/methods , Algorithms , Neural Networks, Computer , Databases, Factual , Signal Processing, Computer-Assisted , Wavelet AnalysisABSTRACT
This paper presents the results of a study of the characteristics of phase synchronization between electrocardiography(ECG) and electroencephalography (EEG) signals during night sleep. Polysomnographic recordings of eight generally healthy subjects and eight patients with obstructive sleep apnea syndrome were selected as experimental data. A feature of this study was the introduction of an instantaneous phase for EEG and ECG signals using a continuous wavelet transform at the heart rate frequency using the concept of time scale synchronization, which eliminated the emergence of asynchronous areas of behavior associated with the "leaving" of the fundamental frequency of the cardiovascular system. Instantaneous phase differences were examined for various pairs of EEG and ECG signals during night sleep, and it was shown that in all cases the phase difference exhibited intermittency. Laminar areas of behavior are intervals of phase synchronization, i.e., phase capture. Turbulent intervals are phase jumps of 2π. Statistical studies of the observed intermittent behavior were carried out, namely, distributions of the duration of laminar sections of behavior were estimated. For all pairs of channels, the duration of laminar phases obeyed an exponential law. Based on the analysis of the movement of the phase trajectory on a rotating plane at the moment of detection of the turbulent phase, it was established that in this case the eyelet intermittency was observed. There was no connection between the statistical characteristics of laminar phase distributions for intermittent behavior and the characteristics of night breathing disorders (apnea syndrome). It was found that changes in statistical characteristics in the phase synchronization of EEG and ECG signals were correlated with blood pressure at the time of signal recording in the subjects, which is an interesting effect that requires further research.
Subject(s)
Electrocardiography , Electroencephalography , Wavelet Analysis , Humans , Electroencephalography/methods , Electrocardiography/methods , Male , Adult , Heart Rate/physiology , Sleep Apnea, Obstructive/physiopathology , Sleep Apnea, Obstructive/diagnosis , Polysomnography/methods , Female , Sleep/physiology , Signal Processing, Computer-Assisted , Middle AgedABSTRACT
Medical image fusion (MIF) techniques are proficient in combining medical images in distinct morphologies to obtain a reliable medical analysis. A single modality image could not offer adequate data for an accurate analysis. Therefore, a novel multimodal MIF-based artificial intelligence (AI) method has been presented. MIF approaches fuse multimodal medical images for exact and reliable medical recognition. Multimodal MIF improves diagnostic accuracy and clinical decision-making by combining complementary data in different imaging modalities. This article presents a new multimodal medical image fusion model utilizing Modified DWT with an Arithmetic Optimization Algorithm (MMIF-MDWTAOA) approach. The MMIF-MDWTAOA approach aims to generate a fused image with the significant details and features from each modality, leading to an elaborated depiction for precise interpretation by medical experts. The bilateral filtering (BF) approach is primarily employed for noise elimination. Next, the image decomposition process uses a modified discrete wavelet transform (MDWT) approach. However, the approximation coefficient of modality_1 and the detailed coefficient of modality_2 can be fused interchangeably. Furthermore, a fusion rule is derived from combining the multimodality data, and the AOA model is enforced to ensure the optimum selection of the fusion rule parameters. A sequence of simulations is accomplished to validate the enhanced output of the MMIF-MDWTAOA technique. The investigational validation of the MMIF-MDWTAOA technique showed the highest entropy values of 7.568 and 7.741 bits/pixel over other approaches.
Subject(s)
Algorithms , Multimodal Imaging , Wavelet Analysis , Humans , Multimodal Imaging/methods , Image Processing, Computer-Assisted/methods , Image Interpretation, Computer-Assisted/methods , Artificial Intelligence , Tomography, X-Ray Computed/methodsABSTRACT
In response to the vulnerability of image encryption techniques to chosen plaintext attacks, this paper proposes a secure image communication scheme based on two-layer dynamic feedback encryption and discrete wavelet transform (DWT) information hiding. The proposed scheme employs a plaintext correlation and intermediate ciphertext feedback mechanism, and combines chaotic systems, bit-level permutation, bilateral diffusion, and dynamic confusion to ensure the security and confidentiality of transmitted images. Firstly, a dynamically chaotic encryption sequence associated with a secure plaintext hash value is generated and utilized for the first round of bit-level permutation, bilateral diffusion, and dynamic confusion, resulting in an intermediate ciphertext image. Similarly, the characteristic values of the intermediate ciphertext image are used to generate dynamically chaotic encryption sequences associated with them. These sequences are then employed for the second round of bit-level permutation, bilateral diffusion, and dynamic confusion to gain the final ciphertext image. The ciphertext image hidden by DWT also provides efficient encryption, higher level of security and robustness to attacks. This technology offers indiscernible secret data insertion, rendering it challenging for assailants to spot or extract concealed information. By combining the proposed dynamic closed-loop feedback secure image encryption scheme based on the 2D-SLMM chaotic system with DWT-based hiding, a comprehensive and robust image encryption approach can be achieved. According to the results of theoretical research and experimental simulation, our encryption scheme has dynamic encryption effect and reliable security performance. The scheme is highly sensitive to key and plaintext, and can effectively resist various common encryption attacks and maintain good robustness. Therefore, our proposed encryption algorithm is an ideal digital image privacy protection technology, which has a wide range of practical application prospects.
Subject(s)
Algorithms , Computer Security , Wavelet Analysis , Feedback , ConfidentialityABSTRACT
Objective.Due to the difficulty in acquiring motor imagery electroencephalography (MI-EEG) data and ensuring its quality, insufficient training data often leads to overfitting and inadequate generalization capabilities of deep learning-based classification networks. Therefore, we propose a novel data augmentation method and deep learning classification model to enhance the decoding performance of MI-EEG further.Approach.The raw EEG signals were transformed into the time-frequency maps as the input to the model by continuous wavelet transform. An improved Wasserstein generative adversarial network with gradient penalty data augmentation method was proposed, effectively expanding the dataset used for model training. Additionally, a concise and efficient deep learning model was designed to improve decoding performance further.Main results.It has been demonstrated through validation by multiple data evaluation methods that the proposed generative network can generate more realistic data. Experimental results on the BCI Competition IV 2a and 2b datasets and the actual collected dataset show that classification accuracies are 83.4%, 89.1% and 73.3%, and Kappa values are 0.779, 0.782 and 0.644, respectively. The results indicate that the proposed model outperforms state-of-the-art methods.Significance.Experimental results demonstrate that this method effectively enhances MI-EEG data, mitigates overfitting in classification networks, improves MI classification accuracy, and holds positive implications for MI tasks.
Subject(s)
Brain-Computer Interfaces , Electroencephalography , Imagination , Neural Networks, Computer , Electroencephalography/methods , Electroencephalography/classification , Humans , Imagination/physiology , Deep Learning , Wavelet AnalysisABSTRACT
Sarcopenia is a comprehensive degenerative disease with the progressive loss of skeletal muscle mass with age, accompanied by the loss of muscle strength and muscle dysfunction. Individuals with unmanaged sarcopenia may experience adverse outcomes. Periodically monitoring muscle function to detect muscle degeneration caused by sarcopenia and treating degenerated muscles is essential. We proposed a digital biomarker measurement technique using surface electromyography (sEMG) with electrical stimulation and wearable device to conveniently monitor muscle function at home. When motor neurons and muscle fibers are electrically stimulated, stimulated muscle contraction signals (SMCSs) can be obtained using an sEMG sensor. As motor neuron activation is important for muscle contraction and strength, their action potentials for electrical stimulation represent the muscle function. Thus, the SMCSs are closely related to muscle function, presumptively. Using the SMCSs data, a feature vector concatenating spectrogram-based features and deep learning features extracted from a convolutional neural network model using continuous wavelet transform images was used as the input to train a regression model for measuring the digital biomarker. To verify muscle function measurement technique, we recruited 98 healthy participants aged 20-60 years including 48 [49%] men who volunteered for this study. The Pearson correlation coefficient between the label and model estimates was 0.89, suggesting that the proposed model can robustly estimate the label using SMCSs, with mean error and standard deviation of -0.06 and 0.68, respectively. In conclusion, measuring muscle function using the proposed system that involves SMCSs is feasible.
Subject(s)
Biomarkers , Electric Stimulation , Electromyography , Muscle Contraction , Muscle, Skeletal , Neural Networks, Computer , Wearable Electronic Devices , Humans , Electromyography/methods , Male , Muscle, Skeletal/physiology , Muscle Contraction/physiology , Adult , Female , Algorithms , Sarcopenia/physiopathology , Sarcopenia/diagnosis , Wavelet Analysis , Middle Aged , Deep Learning , Motor Neurons/physiology , Young Adult , Action Potentials/physiology , Healthy VolunteersABSTRACT
Sleep is an integral and vital component of human life, contributing significantly to overall health and well-being, but a considerable number of people worldwide experience sleep disorders. Sleep disorder diagnosis heavily depends on accurately classifying sleep stages. Traditionally, this classification has been performed manually by trained sleep technologists that visually inspect polysomnography records. However, in order to mitigate the labor-intensive nature of this process, automated approaches have been developed. These automated methods aim to streamline and facilitate sleep stage classification. This study aims to classify sleep stages in a dataset comprising subjects with insomnia, PLM, and sleep apnea. The dataset consists of PSG recordings from the multi-ethnic study of atherosclerosis (MESA) cohort of the national sleep research resource (NSRR), including 2056 subjects. Among these subjects, 130 have insomnia, 39 suffer from PLM, 156 have sleep apnea, and the remaining 1731 are classified as good sleepers. This study proposes an automated computerized technique to classify sleep stages, developing a machine-learning model with explainable artificial intelligence (XAI) capabilities using wavelet-based Hjorth parameters. An optimal biorthogonal wavelet filter bank (BOWFB) has been employed to extract subbands (SBs) from 30 seconds of electroencephalogram (EEG) epochs. Three EEG channels, namely: Fz_Cz, Cz_Oz, and C4_M1, are employed to yield an optimum outcome. The Hjorth parameters extracted from SBs were then fed to different machine learning algorithms. To gain an understanding of the model, in this study, we used SHAP (Shapley Additive explanations) method. For subjects suffering from the aforementioned diseases, the model utilized features derived from all channels and employed an ensembled bagged trees (EnBT) classifier. The highest accuracy of 86.8%, 87.3%, 85.0%, 84.5%, and 83.8% is obtained for the insomniac, PLM, apniac, good sleepers and complete datasets, respectively. Using these techniques and datasets, the study aims to enhance sleep stage classification accuracy and improve understanding of sleep disorders such as insomnia, PLM, and sleep apnea.
Subject(s)
Automation , Sleep Initiation and Maintenance Disorders , Wavelet Analysis , Humans , Sleep Initiation and Maintenance Disorders/physiopathology , Sleep Initiation and Maintenance Disorders/diagnosis , Sleep Apnea Syndromes/diagnosis , Sleep Apnea Syndromes/physiopathology , Male , Polysomnography , Female , Middle Aged , Aged , Nocturnal Myoclonus Syndrome/diagnosis , Nocturnal Myoclonus Syndrome/physiopathology , Sleep/physiology , Sleep Stages , Signal Processing, Computer-AssistedABSTRACT
The paper presents a validation of novel multichannel ballistocardiography (BCG) measuring system, enabling heartbeat detection from information about movements during myocardial contraction and dilatation of arteries due to blood expulsion. The proposed methology includes novel sensory system and signal processing procedure based on Wavelet transform and Hilbert transform. Because there are no existing recommendations for BCG sensor placement, the study focuses on investigation of BCG signal quality measured from eight different locations within the subject's body. The analysis of BCG signals is primarily based on heart rate (HR) calculation, for which a J-wave detection based on decision-making processes was used. Evaluation of the proposed system was made by comparing with electrocardiography (ECG) as a gold standard, when the averaged signal from all sensors reached HR detection sensitivity higher than 95% and two sensors showed a significant difference from ECG measurement.
Subject(s)
Ballistocardiography , Electrocardiography , Heart Rate , Humans , Ballistocardiography/methods , Heart Rate/physiology , Electrocardiography/methods , Male , Adult , Female , Signal Processing, Computer-Assisted , Young Adult , Wavelet AnalysisABSTRACT
The surging popularity of virtual reality (VR) technology raises concerns about VR-induced motion sickness, linked to discomfort and nausea in simulated environments. Our method involves in-depth analysis of EEG data and user feedback to train a sophisticated deep learning model, utilizing an enhanced GRU network for identifying motion sickness patterns. Following comprehensive data pre-processing and feature engineering to ensure input accuracy, a deep learning model is trained using supervised and unsupervised techniques for classifying and predicting motion sickness severity. Rigorous training and validation procedures confirm the model's robustness across diverse scenarios. Research results affirm our deep learning model's 84.9% accuracy in classifying and predicting VR-induced motion sickness, surpassing existing models. This information is vital for improving the VR experience and advancing VR technology.
Subject(s)
Deep Learning , Electroencephalography , Motion Sickness , Virtual Reality , Humans , Motion Sickness/physiopathology , Electroencephalography/methods , Adult , Male , Female , Wavelet Analysis , Young AdultABSTRACT
Epilepsy is one of the most well-known neurological disorders globally, leading to individuals experiencing sudden seizures and significantly impacting their quality of life. Hence, there is an urgent necessity for an efficient method to detect and predict seizures in order to mitigate the risks faced by epilepsy patients. In this paper, a new method for seizure detection and prediction is proposed, which is based on multi-class feature fusion and the convolutional neural network-gated recurrent unit-attention mechanism (CNN-GRU-AM) model. Initially, the Electroencephalography (EEG) signal undergoes wavelet decomposition through the Discrete Wavelet Transform (DWT), resulting in six subbands. Subsequently, time-frequency domain and nonlinear features are extracted from each subband. Finally, the CNN-GRU-AM further extracts features and performs classification. The CHB-MIT dataset is used to validate the proposed approach. The results of tenfold cross validation show that our method achieved a sensitivity of 99.24% and 95.47%, specificity of 99.51% and 94.93%, accuracy of 99.35% and 95.16%, and an AUC of 99.34% and 95.15% in seizure detection and prediction tasks, respectively. The results show that the method proposed in this paper can effectively achieve high-precision detection and prediction of seizures, so as to remind patients and doctors to take timely protective measures.
Subject(s)
Deep Learning , Electroencephalography , Epilepsy , Seizures , Humans , Electroencephalography/methods , Seizures/diagnosis , Epilepsy/diagnosis , Epilepsy/physiopathology , Neural Networks, Computer , Wavelet Analysis , Algorithms , Signal Processing, Computer-AssistedABSTRACT
Seizure is a common neurological disorder that usually manifests itself in recurring seizure, and these seizures can have a serious impact on a person's life and health. Therefore, early detection and diagnosis of seizure is crucial. In order to improve the efficiency of early detection and diagnosis of seizure, this paper proposes a new seizure detection method, which is based on discrete wavelet transform (DWT) and multi-channel long- and short-term memory-like spiking neural P (LSTM-SNP) model. First, the signal is decomposed into 5 levels by using DWT transform to obtain the features of the components at different frequencies, and a series of time-frequency features in wavelet coefficients are extracted. Then, these different features are used to train a multi-channel LSTM-SNP model and perform seizure detection. The proposed method achieves a high seizure detection accuracy on the CHB-MIT dataset: 98.25% accuracy, 98.22% specificity and 97.59% sensitivity. This indicates that the proposed epilepsy detection method can show competitive detection performance.
Subject(s)
Electroencephalography , Neural Networks, Computer , Seizures , Wavelet Analysis , Humans , Seizures/diagnosis , Seizures/physiopathology , Electroencephalography/methods , Memory, Short-Term/physiology , Models, Neurological , Memory, Long-Term/physiology , Sensitivity and SpecificityABSTRACT
BACKGROUND: Electrocardiograms (ECGs) are vital for diagnosing cardiac conditions but obtaining clean signals in Left Ventricular Assist Device (LVAD) patients is hindered by electromagnetic interference (EMI). Traditional filters have limited efficacy. There is a current need for an easy and effective method. METHODS: Raw ECG data obtained from 5 patients with LVADs. LVAD types included HeartMate II, III at multiple impeller speeds, and a case with HeartMate III and a ProtekDuo. ECG spectral profiles were examined ensuring the presence of diverse types of EMI in the study. ECGs were then processed with four denoising techniques: Moving Average Filter, Finite Impulse Response Filter, Fast Fourier Transform, and Discrete Wavelet Transform. RESULTS: Discrete Wavelet Transform proved as the most promising method. It offered a one solution fits all, enabling automatic processing with minimal user input while preserving crucial high-frequency components and reducing LVAD EMI artifacts. CONCLUSION: Our study demonstrates the practicality and efficiency of Discrete Wavelet Transform in obtaining high-fidelity ECGs in LVAD patients. This method could enhance clinical diagnosis and monitoring.
Subject(s)
Algorithms , Electrocardiography , Heart-Assist Devices , Wavelet Analysis , Humans , Electrocardiography/methods , Artifacts , Reproducibility of Results , Sensitivity and Specificity , Male , Diagnosis, Computer-Assisted/methods , Female , Middle Aged , Signal-To-Noise RatioABSTRACT
Traditional brightness-mode ultrasound imaging is primarily constrained by the low specificity among tissues and the inconsistency among sonographers. The major cause is the imaging method that represents the amplitude of echoes as brightness and ignores other detailed information, leaving sonographers to interpret based on organ contours that depend highly on specific imaging planes. Other ultrasound imaging modalities, color Doppler imaging or shear wave elastography, overlay motion or stiffness information to brightness-mode images. However, tissue-specific scattering properties and spectral patterns remain unknown in ultrasound imaging. Here we demonstrate that the distribution (size and average distance) of scattering particles leads to characteristic wavelet spectral patterns, which enables tissue recognition and high-contrast ultrasound imaging. Ultrasonic wavelet spectra from similar particle distributions tend to cluster in the eigenspace according to principal component analysis, whereas those with different distributions tend to be distinguishable from one another. For each distribution, a few wavelet spectra are unique and act as a fingerprint to recognize the corresponding tissue. Illumination of specific tissues and organs with designated colors according to the recognition results yields high-contrast ultrasound imaging. The fully-colorized tissue-specific ultrasound imaging potentially simplifies the interpretation and promotes consistency among sonographers, or even enables the applicability for non-professionals.
Subject(s)
Wavelet Analysis , Color , Ultrasonography/methods , Phantoms, Imaging , Animals , Principal Component Analysis , HumansABSTRACT
Anticancer peptides (ACPs) perform a promising role in discovering anti-cancer drugs. The growing research on ACPs as therapeutic agent is increasing due to its minimal side effects. However, identifying novel ACPs using wet-lab experiments are generally time-consuming, labor-intensive, and expensive. Leveraging computational methods for fast and accurate prediction of ACPs would harness the drug discovery process. Herein, a machine learning-based predictor, called PLMACPred, is developed for identifying ACPs from peptide sequence only. PLMACPred adopted a set of encoding schemes representing evolutionary-property, composition-property, and protein language model (PLM), i.e., evolutionary scale modeling (ESM-2)- and ProtT5-based embedding to encode peptides. Then, two-dimensional (2D) wavelet denoising (WD) was employed to remove the noise from extracted features. Finally, ensemble-based cascade deep forest (CDF) model was developed to identify ACP. PLMACPred model attained superior performance on all three benchmark datasets, namely, ACPmain, ACPAlter, and ACP740 over tenfold cross validation and independent dataset. PLMACPred outperformed the existing models and improved the prediction accuracy by 18.53%, 2.4%, 7.59% on ACPmain, ACPalter, ACP740 dataset, respectively. We showed that embedding from ProtT5 and ESM-2 was capable of capturing better contextual information from the entire sequence than the other encoding schemes for ACP prediction. For the explainability of proposed model, SHAP (SHapley Additive exPlanations) method was used to analyze the feature effect on the ACP prediction. A list of novel sequence motifs was proposed from the ACP sequence using MEME suites. We believe, PLMACPred will support in accelerating the discovery of novel ACPs as well as other activities of microbial peptides.
Subject(s)
Antineoplastic Agents , Computational Biology , Machine Learning , Peptides , Peptides/chemistry , Antineoplastic Agents/chemistry , Computational Biology/methods , Humans , Databases, Protein , Algorithms , Wavelet AnalysisABSTRACT
The paper addresses the issue of ensuring the authenticity and copyright of medical images in telemedicine applications, with a specific emphasis on watermarking methods. While several systems only concentrate on identifying tampering in medical images, others also provide the capacity to restore the tampered regions upon detection. While several authentication techniques in medical imaging have successfully achieved their goals, previous research underscores a notable deficiency: the resilience of these schemes against unintentional attacks has not been sufficiently examined or emphasized in previous research. This indicates the need for further development and investigation in improving the robustness of medical image authentication techniques against unintentional attacks. This research proposes a Reversible-Zero Watermarking approach as a solution to address these problems. The new approach merges the advantages of both the reversible and zero watermarking techniques. This system is comprised of two parts. The first part is a zero-watermarking technique that uses VGG19-based feature extraction and watermark information to establish an ownership share. The second part incorporates this ownership share into the image in a reversible manner using a combination of a discrete wavelet transform, an integer wavelet transform, and a difference expansion. Research findings confirm that the suggested watermarking approach for medical images demonstrates substantial enhancements compared to current methodologies. Research findings indicate that NC values are often around 0.9 for different attacks, whereas BER values are close to 0. It demonstrates exceptional qualities in being imperceptible, distinguishable, and robust. Additionally, the system provides a persistent verification feature that functions independently of disputes or third-party storage, making it the preferred choice in the domain of medical image watermarking.
Subject(s)
Computer Security , Humans , Diagnostic Imaging/methods , Algorithms , Telemedicine , Image Processing, Computer-Assisted/methods , Wavelet AnalysisABSTRACT
OBJECTIVE: Motivated by Health Care 4.0, this study aims to reducing the dimensionality of traditional EEG features based on manual extracted features, including statistical features in the time and frequency domains. METHODS: A total of 22 multi-scale features were extracted from the UNM and Iowa datasets using a 4th order Butterworth filter and wavelet packet transform. Based on single-channel validation, 29 channels with the highest R2 scores were selected from a pool of 59 common channels. The proposed channel selection scheme was validated on the UNM dataset and tested on the Iowa dataset to compare its generalizability against models trained without channel selection. RESULTS: The experimental results demonstrate that the proposed model achieves an optimal classification accuracy of 100%. Additionally, the generalization capability of the channel selection method is validated through out-of-sample testing based on the Iowa dataset Conclusions: Using single-channel validation, we proposed a channel selection scheme based on traditional statistical features, resulting in a selection of 29 channels. This scheme significantly reduced the dimensionality of EEG feature vectors related to Parkinson's disease by 50%. Remarkably, this approach demonstrated considerable classification performance on both the UNM and Iowa datasets. For the closed-eye state, the highest classification accuracy achieved was 100%, while for the open-eye state, the highest accuracy reached 93.75%.