ABSTRACT
Mujer de 55 años que refiere pérdida visual progresiva en el ojo derecho presenta un escotoma juncional en un estudio campimétrico. Se practica resonancia magnética, que muestra un aneurisma de la arteria cerebral media derecha con compromiso quiasmático ipsolateral
The case concerns a 55 year-old female patient with progressive visual decrease in her right eye that showed a junctional scotoma in the visual field study. A magnetic resonance scan was performed, which showed a right middle cerebral artery aneurysm with ipsolateral chiasmatic involvement
Subject(s)
Humans , Female , Middle Aged , Intracranial Aneurysm/complications , Scotoma/etiology , Aneurysm, Ruptured/complications , Delayed Diagnosis , Dry Eye Syndromes/complications , Dyspnea/etiology , Fatal Outcome , Intracranial Aneurysm/diagnostic imaging , Magnetic Resonance Imaging , Nerve Compression Syndromes/etiology , Optic Chiasm/physiopathology , Scotoma/physiopathology , Subarachnoid Hemorrhage/etiology , Tomography, Optical Coherence , Visual Field Tests , Visual FieldsABSTRACT
The case concerns a 55 year-old female patient with progressive visual decrease in her right eye that showed a junctional scotoma in the visual field study. A magnetic resonance scan was performed, which showed a right middle cerebral artery aneurysm with ipsolateral chiasmatic involvement.
Subject(s)
Intracranial Aneurysm/complications , Scotoma/etiology , Aneurysm, Ruptured/complications , Delayed Diagnosis , Dry Eye Syndromes/complications , Dyspnea/etiology , Fatal Outcome , Female , Humans , Intracranial Aneurysm/diagnostic imaging , Magnetic Resonance Imaging , Middle Aged , Nerve Compression Syndromes/etiology , Optic Chiasm/physiopathology , Scotoma/physiopathology , Subarachnoid Hemorrhage/etiology , Tomography, Optical Coherence , Visual Field Tests , Visual FieldsABSTRACT
CASO CLÍNICO: Mujer de 40 años, infectada 6 meses antes de acudir a consulta por el virus del Zika. Dos semanas después comenzó con pérdida de agudeza visual (AV) progresiva e indolora que fue tratada con corticoides tópicos. Su AV mejoró, pero desde entonces refiere pérdida de campo visual (CV) y ceguera nocturna. En la exploración oftalmológica presenta graves secuelas compatibles con neurorretinopatía autoinmune. Dada la relación temporal con la infección por zika se diagnostica de neurorretinopatía autoinmune no paraneoplásica por zika. Se instaura terapia inmunosupresora con bolos de corticoides e infliximab. Discusión: El virus del Zika puede desencadenar una neurorretinopatía autoinmune no paraneoplásica. El diagnóstico es fundamentalmente clínico. Precisa tratamiento inmunosupresor, siendo de máxima importancia el diagnóstico precoz
CASE REPORT: A 40-year-old woman diagnosed with Zika virus infection 6 months before she arrived at this hospital. She referred to a progressive and painless vision loss, of 2 weeks onset after the infection diagnosis. She was treated with topical steroids. Previous visual acuity was recovered, but she still refers to reduced visual field and nyctalopia. Ophthalmologic examination revealed severe retinal sequels, compatible with autoimmune retinopathy. Based on the clinical features and the temporal relationship with Zika virus infection, non-para-neoplastic autoimmune retinopathy was diagnosed and managed with steroids and infliximab. DISCUSSION: Zika virus can trigger a non-para-neoplastic autoimmune retinopathy. The diagnosis is based on clinical features, and requires early immunosuppressive therapy
Subject(s)
Humans , Female , Adult , Zika Virus Infection/complications , Autoimmunity , Retinal Diseases/diagnosis , Retinal Diseases/immunology , Early Diagnosis , Paraneoplastic Syndromes, Nervous System/diagnosis , Zika Virus Infection/drug therapy , Immunosuppressive Agents/therapeutic use , Adrenal Cortex Hormones/therapeutic use , Infliximab/therapeutic useABSTRACT
CASE REPORT: A 40-year-old woman diagnosed with Zika virus infection 6 months before she arrived at this hospital. She referred to a progressive and painless vision loss, of 2 weeks onset after the infection diagnosis. She was treated with topical steroids. Previous visual acuity was recovered, but she still refers to reduced visual field and nyctalopia. Ophthalmologic examination revealed severe retinal sequels, compatible with autoimmune retinopathy. Based on the clinical features and the temporal relationship with Zika virus infection, non-para-neoplastic autoimmune retinopathy was diagnosed and managed with steroids and infliximab. DISCUSSION: Zika virus can trigger a non-para-neoplastic autoimmune retinopathy. The diagnosis is based on clinical features, and requires early immunosuppressive therapy.
Subject(s)
Autoimmune Diseases of the Nervous System/virology , Retinal Diseases/immunology , Retinal Diseases/virology , Zika Virus Infection/complications , Adult , Female , HumansABSTRACT
CASO CLÍNICOS: Presentamos los casos de dos pacientes con carcinoma basocelular periocular palpebral, que recibieron imiquimod tópico al 5%, con buena respuesta. Ambos presentaban un estado funcional que desaconsejaba el tratamiento quirúrgico. CONCLUSIÓN: La crema de imiquimod al 5% ha demostrado ser una alternativa eficaz al tratamiento quirúrgico de tumores basocelulares perioculares, especialmente en aquellos casos en los que la cirugía no es posible
CLINICAL CASE: The cases are presented of two patients with periocular basal cell carcinoma of the eyelid who received topical imiquimod 5%, with a good response. Both had a functional state that contraindicated surgical treatment. CONCLUSION: Imiquimod cream 5% was shown to be an effective alternative to surgical treatment of periocular basal cell carcinoma, especially in those cases where surgery is not possible
Subject(s)
Humans , Male , Female , Middle Aged , Aged, 80 and over , Carcinoma, Basal Cell/pathology , Eyelid Neoplasms/pathology , Immunologic Factors/therapeutic use , Carcinoma, Basal Cell/drug therapy , Eyelid Neoplasms/drug therapy , Administration, Topical , AIDS-Related Opportunistic Infections/diagnosisABSTRACT
CASO CLÍNICO: Una mujer de 33 años consulta por conjuntivitis granulomatosa unilateral, adenopatías regionales homolaterales y fiebre. Se demuestra una infección por Bartonella henselae mediante inmunofluorescencia indirecta y se establece el diagnóstico de síndrome oculoglandular de Parinaud. La evolución después de tratamiento con doxiciclina oral es satisfactoria. Discusión: El síndrome oculoglandular de Parinaud es la manifestación ocular más frecuente de una infección por Bartonella henselae
CLINICAL CASE: 33-year old woman presents with unilateral granulomatous conjunctivitis, ipsilateral regional lymphadenopathy and fever. A Bartonella henselae infection is demonstrated by indirect immunofluorescence, and a diagnosis of a Parinauds oculoglandular syndrome is established. Outcome after treatment with oral doxycycline is satisfactory. Discussion: Parinauds oculoglandular syndrome is the most frequent ocular manifestation of a Bartonella henselae infection
Subject(s)
Humans , Female , Adult , Ocular Motility Disorders/diagnosis , Conjunctivitis/etiology , Cat-Scratch Disease/complications , Bartonella Infections/complications , Bartonella henselae/pathogenicity , Doxycycline/therapeutic useABSTRACT
CLINICAL CASE: A 33-year old woman presents with unilateral granulomatous conjunctivitis, ipsilateral regional lymphadenopathy and fever. A Bartonella henselae infection is demonstrated by indirect immunofluorescence, and a diagnosis of a Parinaud's oculoglandular syndrome is established. Outcome after treatment with oral doxycycline is satisfactory. DISCUSSION: Parinaud's oculoglandular syndrome is the most frequent ocular manifestation of a Bartonella henselae infection.
Subject(s)
Bartonella henselae/isolation & purification , Cat-Scratch Disease/complications , Ocular Motility Disorders/etiology , Adult , Amoxicillin-Potassium Clavulanate Combination/therapeutic use , Animals , Anti-Bacterial Agents/therapeutic use , Antibodies, Bacterial/blood , Bartonella henselae/immunology , Cat-Scratch Disease/drug therapy , Cat-Scratch Disease/microbiology , Cats , Doxycycline/therapeutic use , Female , Fluorescent Antibody Technique, Indirect , Humans , Leg Injuries/complications , Leg Injuries/microbiology , Ocular Motility Disorders/diagnosis , Ocular Motility Disorders/drug therapy , Tomography, X-Ray Computed , Wound Infection/complications , Wound Infection/microbiologyABSTRACT
CLINICAL CASES: The cases are presented of two patients with periocular basal cell carcinoma of the eyelid who received topical imiquimod 5%, with a good response. Both had a functional state that contraindicated surgical treatment. CONCLUSION: Imiquimod cream 5% was shown to be an effective alternative to surgical treatment of periocular basal cell carcinoma, especially in those cases where surgery is not possible.