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1.
BMC Surg ; 24(1): 106, 2024 Apr 13.
Article in English | MEDLINE | ID: mdl-38614997

ABSTRACT

BACKGROUND: Pericardial defect that occurs after intrapericardial pneumonectomy can cause many fatal complications, and closing the defect with mesh is a widely used surgical method to prevent these complications. METHODS: Data of patients who underwent intrapericardial pneumonectomy and pericardial resection in our clinic between October 2010 and June 2022 were retrospectively reviewed. Patients were divided into two groups, those who had prolene mesh used to close the pericardial defect and those who underwent the "Rug Weave" technique we proposed as an alternative, and the results were compared. RESULTS: The study included 23 patients, one of whom was female. All patients underwent surgery due to malignancy. The vast majority of the patients had a diagnosis of squamous cell lung carcinoma (86.9%). Atrium was added to three patients and rib resection was added to one patient during intrapericardial pneumonectomy and pericardial resection. There was no significant difference between the two groups in terms of average age, gender, and length of hospital stay. There was no significant difference between the two groups in terms of complications, including atrial fibrillation, which is commonly seen in these patients (p = 0.795). The Rug Weave group had an average defect width of 23.96 cm2 and was found to be advantageous in terms of overall survival compared to the mesh group (p = 0.017). CONCLUSIONS: The "Rug Weave" technique we proposed for closing pericardial defects after pneumonectomy can be used as a cheaper method safely and effectively that reduces complications as much as the traditional method of using mesh.


Subject(s)
Heart Diseases , Lung Neoplasms , Humans , Female , Retrospective Studies , Pneumonectomy , Pericardium/surgery , Lung Neoplasms/surgery
2.
Mil Med ; 2024 Apr 08.
Article in English | MEDLINE | ID: mdl-38587902

ABSTRACT

INTRODUCTION: Health services in the theater/district areas often contain difficulties. Although telemedicine has a huge potential to support medics in the area, there are challenges as well. Our aim is to evaluate the telemedicine support that can be provided to the medics from the perspective of course instructors. MATERIALS AND METHODS: Our study was carried out in The University of Health Sciences, Türkiye. All of the instructors of a medic course were asked to fill a 13-question questionnaire and Likert-type scale, sent via e-mail. Among 79 instructors, 71 of them (55 physicians, 16 nonphysicians) responded and were included in the study. The distributions of the categorical variables in the groups were analyzed with the Pearson Chi-square. RESULTS: Of the 71 participants, 37 (52.11%) stated that there is a need for legal and ethical regulations for telemedicine (medical liability, malpractice, obtaining consent from the casualties, civilians, cross border missions, and rank-related problems) and patients' rights, additionally, to clarify the responsibilities of the doctors giving telemedicine support and the medics in the area. It was observed that physicians' and nonphysician group's opinions about the telepsychotherapy were statistically significantly different (χ2 = 8.675, P = .013). CONCLUSIONS: Most of the instructors believed that telemedicine could carry the knowledge and skills of specialist physicians to the field of operation. Access to high-quality health services in a short time through telemedicine support can increase the courage and commitment of the personnel. It is thought that with telemedicine, medics will not feel alone in the field, their worries about making wrong decisions will decrease, and their knowledge and skills will increase. Participants were particularly concerned about who will be held responsible for problems arising from interventions carried out using telemedicine, and strict legal and medical regulations are needed.

3.
Mol Ecol Resour ; 24(5): e13960, 2024 Jul.
Article in English | MEDLINE | ID: mdl-38676702

ABSTRACT

There is growing interest in uncovering genetic kinship patterns in past societies using low-coverage palaeogenomes. Here, we benchmark four tools for kinship estimation with such data: lcMLkin, NgsRelate, KIN, and READ, which differ in their input, IBD estimation methods, and statistical approaches. We used pedigree and ancient genome sequence simulations to evaluate these tools when only a limited number (1 to 50 K, with minor allele frequency ≥0.01) of shared SNPs are available. The performance of all four tools was comparable using ≥20 K SNPs. We found that first-degree related pairs can be accurately classified even with 1 K SNPs, with 85% F1 scores using READ and 96% using NgsRelate or lcMLkin. Distinguishing third-degree relatives from unrelated pairs or second-degree relatives was also possible with high accuracy (F1 > 90%) with 5 K SNPs using NgsRelate and lcMLkin, while READ and KIN showed lower success (69 and 79% respectively). Meanwhile, noise in population allele frequencies and inbreeding (first-cousin mating) led to deviations in kinship coefficients, with different sensitivities across tools. We conclude that using multiple tools in parallel might be an effective approach to achieve robust estimates on ultra-low-coverage genomes.


Subject(s)
Benchmarking , Pedigree , Polymorphism, Single Nucleotide , Benchmarking/methods , Humans , Gene Frequency , DNA, Ancient/analysis , Computer Simulation , Genetics, Population/methods , Computational Biology/methods
4.
Updates Surg ; 2024 Mar 17.
Article in English | MEDLINE | ID: mdl-38494568

ABSTRACT

PURPOSE: Bronchopleural fistula most commonly occurs after pneumonectomies, with high morbidity and mortality. A preventive approach is essential. Risk factors can be classified depending on the patient, anatomy, surgical technique, and other causes. METHODS: Patients (n = 370) who underwent pneumonectomy between 2010 and 2020 were evaluated. The digital media and archive files of the patients (n = 299) were reviewed retrospectively. RESULTS: While 271 patients (90.6%) were male, 28 (9.4%) were female. The mean age was 56.63 years. The bronchopleural fistula rate was 14.7% (44/299). Serum protein deficiency, right pneumonectomy, completion pneumonectomy, bronchial manual suturing, advanced stage, prolongation of time after neoadjuvant therapy, length of drain and hospital stay, tissue support for the stump, and short bronchial stump were significant for bronchopleural fistula. Smoking in patients operated on for malignancy and low serum albumin value in benign and chronic infectious diseases were significant in terms of fistula. In patients who developed bronchopleural fistula, the 5-year survival rate was 18.4%. CONCLUSION: The most important risk factors in bronchopleural fistula depend on the surgical technique and so are completely preventable. Contrary to the literature, short stump and tissue support to the stump were found to be risk factors for fistula. In addition, the effect of the time between neoadjuvant therapy and operation should be examined in further studies.

5.
J Pediatr Urol ; 2024 Mar 15.
Article in English | MEDLINE | ID: mdl-38523048

ABSTRACT

BACKGROUND: Maximum voided volumes (MVV) and maximum bladder capacities (MBC) are important parameters in the evaluation of lower urinary tract functions in children. However, consistency of MVV and MBC measurements between voiding diary (VD), uroflowmetry (UF) and cystometrography (CMG) in children with non-neurogenic lower urinary tract dysfunction (LUTD) has not been addressed specifically. OBJECTIVE: We aimed to compare the MVV in VD and UF and MBC in CMG in children with non-neurogenic LUT dysfunction and investigate for possible factors for discrepancies. MATERIALS AND METHODS: Children with non-neurogenic LUTD were retrospectively evaluated with a focus on VD, UF, and CMG. VD applied for 2 days and MVV recorded except for first urine in morning. UF repeated in children with <50% of expected bladder capacity (EBC) for age. Highest value and post voiding residual urine (PVR) was recorded. CMG was performed if these conditions were present: High PVR or LUT dysfunction resistant to standard urotherapy (conservative management with biofeedback) and medical therapy (oral anticholinergics) or LUT dysfunction accompanied by VUR or recurrent UTI. MBC in CMG was recorded according to International Children Continence Society (ICCS) standards. MVV and MBC in VD, UF, CMG were compared and possible factors for discrepancy were investigated. RESULTS: 54 children (median age: 10 (4-17) years) were included in the study. 39 (72.2%) were girls, 15 (27.8%) were boys. Median MVV was 232.50 (20-600) ml in VD, 257.50 (69-683) ml in UF and MBC was 184 (31-666) ml in CMG (p = 0.012) (Summary Table). In the subgroup analysis, it was shown that the bladder capacities obtained from all three tests were not compatible with each other in children younger than 10 years of age, in girls, in those with recurrent urinary tract infection, detrusor overactivity, high PVR and normal flow pattern (p = 0.003, p = 0.016, p = 0.029, p < 0.001, p = 0.045, p = 0.03, respectively). DISCUSSION: There is a discrepancy between bladder capacities obtained from VD, UF and CMG In children with non-neurogenic LUT dysfunction. In particular, the lower capacity obtained from invasive urodynamic tests may be related to the poor compliance of children during the procedure. Therefore, when invasive urodynamics is required in these cases, we recommend that maximum cystometric capacity to be evaluated by comparing with voided volumes at UF, VD and other clinical signs and symptoms, and urodynamic parameters in more detail. CONCLUSION: MVV in VD and UF are comparable, but MBC in CMG is lower in children with non-neurogenic LUTD selected for invasive urodynamic studies. More attention should be paid to bladder capacity obtained from urodynamic studies in children exhibiting the characteristics identified in the subgroup analysis. We believe that evaluating bladder capacity values, especially obtained from invasive studies, in conjunction with clinical findings can prevent misdiagnosis, over investigation and overtreatment in children with non-neurogenic LUTD.

6.
Updates Surg ; 76(1): 299-303, 2024 Jan.
Article in English | MEDLINE | ID: mdl-37558972

ABSTRACT

BACKGROUND: Oxidized regenerated cellulose (ORC) is commonly used to control small intraoperative bleedings in lung cancer surgery. However, difficulties in its absorption may lead to complications that can mimic malignancy recurrence in the affected areas, and may require further examination. METHODS: Between 2015 and 2022, patients who underwent malignant tumour resection and lymph node dissection and were subsequently evaluated for suspected lymph node recurrence and underwent EBUS-guided needle biopsy were included in the study. Pathology reports of these patients showed an ORC-related foreign body type granulomatous reaction. Such reactions, caused by delayed absorption of ORC, can mimic malignancy recurrence and result in unnecessary biopsies. RESULTS: In a total of 13 patients (10 males), pathology was observed in 18 lymph node areas after malignant resection and lymph node dissection, and ORC was detected in subcarinal and inferior paratracheal lymph node areas in all patients. The average age of the patients was calculated as 63.1 years (range 51-74). The mean SUVmax value observed in these lymph node areas on PET/CT was 5.22 (range 0-14.36). Although the SUVmax value decreased as the time between surgery and EBUS increased, no statistically significant difference was observed (p = 0.100). CONCLUSION: The study suggests that in cases of suspected unexpected lymph node recurrence in postoperative follow-up of lung cancer, it is important for clinicians to communicate with the surgeon and re-evaluate the use of ORC by reviewing the operative notes. This may help in determining an appropriate further investigation strategy.


Subject(s)
Cellulose , Lung Neoplasms , Positron Emission Tomography Computed Tomography , Male , Humans , Middle Aged , Aged , Retrospective Studies , Lymphatic Metastasis/pathology , Neoplasm Recurrence, Local/pathology , Lung Neoplasms/diagnosis , Lung Neoplasms/surgery , Lung Neoplasms/pathology , Lymph Nodes/pathology , Neoplasm Staging
7.
Indian J Pathol Microbiol ; 66(4): 786-789, 2023.
Article in English | MEDLINE | ID: mdl-38084533

ABSTRACT

Background: Orthopedia homeobox protein (OTP), highlighted as a sensitive and specific marker for pulmonary carcinoids, may provide a more objective criterion for subclassification. Materials and Methods: A total of 110 patients who underwent surgery for pulmonary carcinoids (2009-2019) were included. Gender, age, application complaint, tumor diameter and location, typical and atypical tumor type, lymph node involvement, stage, recurrence, and survival data were evaluated retrospectively with OTP nuclear staining. Results: The sensitivity of OTP was 66.4%. OTP in subclassifying pulmonary carcinoids was not significant. There was no significant relationship between OTP and lymph node involvement, recurrence, and survival. Conclusion: OTP does not provide significant results in the subclassification of typical and atypical carcinoid tumors and the evaluation of recurrence and survival of carcinoid tumor cases.


Subject(s)
Adenoma , Carcinoid Tumor , Carcinoma, Neuroendocrine , Lung Neoplasms , Humans , Retrospective Studies , Homeodomain Proteins/metabolism , Biomarkers, Tumor/analysis , Nerve Tissue Proteins/analysis , Nerve Tissue Proteins/metabolism , Carcinoid Tumor/diagnosis , Carcinoid Tumor/surgery , Lung Neoplasms/diagnosis , Carcinoma, Neuroendocrine/pathology
8.
Arch Ital Urol Androl ; 95(3): 11662, 2023 Oct 03.
Article in English | MEDLINE | ID: mdl-37791547

ABSTRACT

AIM: The voiding diary (VD) yields crucial insights into voiding volumes (VV), voiding frequency (VF), and management habits in children with lower urinary tract (LUT) dysfunction. It is recommended to be conducted for a minimum of 2 days. Nevertheless, certain studies have indicated similarities in voided volumes between days in a three-day VD. This study aims to compare VV and VF values across days based on bladder capacity and symptom scores. MATERIALS AND METHODS: Children who applied to the pediatric urology clinic due to LUT symptoms between 2022 and 2023 were included in the study. Retrospective evaluation was conducted on the records. Children with neurological deficits and incomplete data were excluded from the study. All children were assessed following the guidelines of ICCS and EUA and underwent a 3-day voiding diary. Mean VV and VF values of the whole group for each day were compared and subgroup analyzes were performed in terms of gender, Voiding Dysfunction Symptom Score (VDSS), bladder capacity (BC), and diagnoses. RESULTS: A total of 109 (53 girls (48.6%), 56 boys (51.4%)) children with a median age of 8 (3-17) were included in the study. 77 (70.6%) children were diagnosed with overactive bladder, 8 (7.4%) with dysfunctional voiding, and 24 (22%) with monosymptomatic enuresis nocturne. The mean VVs between days were similar in the whole group (p = 0.759). Moreover, the mean VV of the first day was similar to the average of both the first two days and the three days (p = 0.021, p = 0.490). Also, the maximum and minimum VVs were similar between days (p = 0.942, p = 0.160, respectively). In subgroup analyses based on gender, bladder capacity, and symptom score, mean VV was also found to be similar. VF values were found to be significantly different between days. There was also a difference between VF values in children with VDSS > 8.5 (p = 0.012) and BC/EBC (%) > 65 (p = 0.030). In subgroup analysis for diagnoses, mean and maximum VV and VF were similar between the groups, except for VF (p = 0.026) in OAB. CONCLUSION: While the voided volumes of children with non-neurogenic LUT dysfunctions appear to be consistent across the days of the VD, variations in VF might arise, especially among children with a VDSS of > 8.5 and normal bladder capacity. As a result, we believe that using a VD spanning at least two days could enhance diagnostic accuracy and help prevent unnecessary treatment.


Subject(s)
Urinary Bladder, Overactive , Urinary Incontinence , Male , Female , Humans , Child , Urinary Bladder , Retrospective Studies , Urination
9.
Environ Sci Pollut Res Int ; 30(52): 112357-112367, 2023 Nov.
Article in English | MEDLINE | ID: mdl-37831266

ABSTRACT

Air pollution, a pressing global issue, encompasses various harmful elements, with heavy metals being particularly significant pollutants affecting all forms of life. Effective monitoring and regulation of heavy metal concentrations, especially in the atmosphere, is pivotal. Employing trees as biomonitors emerges as a potent tool, particularly in retrospectively assessing long-term heavy metal contamination trends. This study aims to furnish insights into both tin (Sn) pollutants and the most suitable species for monitoring and mitigating such pollution. Within this study's ambit, samples were collected from Pinus pinaster, Cupressus arizonica, Picea orientalis, Cedrus atlantica, and Pseudotsuga menziesii species in Duzce Province. This area, ranked as the fourth-most air-polluted in Europe according to the World Air Pollution Report, was examined to discern changes in Sn concentration across species, organs, orientations, and age groups over the last four decades. The findings revealed varying potentials for Sn accumulation among the species. Specifically, Pinus pinaster and Picea orientalis were identified as suitable species for monitoring Sn pollution, while Cupressus arizonica, Cedrus atlantica, and Pseudotsuga menziesii exhibited potential for reducing Sn pollution.


Subject(s)
Air Pollutants , Air Pollution , Environmental Pollutants , Metals, Heavy , Picea , Pinus , Pseudotsuga , Tin , Retrospective Studies , Air Pollution/analysis , Metals, Heavy/analysis , Cedrus , Environmental Monitoring , Air Pollutants/analysis
10.
Rev Assoc Med Bras (1992) ; 69(9): e20230475, 2023.
Article in English | MEDLINE | ID: mdl-37729373

ABSTRACT

OBJECTIVE: Foreign body aspiration is one of the childhood emergencies that thoracic surgeons are interested in, and it can cause morbidity and mortality. Although the relationship between various behavioral problems related to children and foreign body aspiration has been investigated so far, there is no study investigating the relationship between maternal temperament and anxiety sensitivity. This study aimed to investigate the relationship between maternal emotional temperament, anxiety sensitivity, and foreign body aspiration. METHODS: Mothers of 18 children with foreign body aspiration have been evaluated by a thoracic surgeon, and 18 healthy controls have also been included in the study. Maternal emotional temperament has been measured with the Temperament Evaluation of Memphis, Pisa, Paris, and San Diego - Auto questionnaire scale, and anxiety sensitivity has been measured with the Anxiety Sensitivity Index-3. RESULTS: There has been no statistically significant difference between groups in terms of maternal emotional temperament and anxiety sensitivity. In the logistic regression analysis conducted to determine the predictors of foreign body aspiration, it is determined that the mother's anxious temperament has predicted foreign body aspiration significantly. CONCLUSION: As a result of the study, it can be concluded that mothers' anxious temperament can be considered a risk factor for foreign body aspiration because it affects parenting skills and children's ability to manage behavioral problems. Consistent results could be able to be obtained with studies including larger samples on the subject.


Subject(s)
Foreign Bodies , Temperament , Child , Humans , Female , Anxiety , Anxiety Disorders , Mothers , Foreign Bodies/complications
11.
Rev. Assoc. Med. Bras. (1992, Impr.) ; 69(9): e20230475, set. 2023. tab
Article in English | LILACS-Express | LILACS | ID: biblio-1514733

ABSTRACT

SUMMARY OBJECTIVE: Foreign body aspiration is one of the childhood emergencies that thoracic surgeons are interested in, and it can cause morbidity and mortality. Although the relationship between various behavioral problems related to children and foreign body aspiration has been investigated so far, there is no study investigating the relationship between maternal temperament and anxiety sensitivity. This study aimed to investigate the relationship between maternal emotional temperament, anxiety sensitivity, and foreign body aspiration. METHODS: Mothers of 18 children with foreign body aspiration have been evaluated by a thoracic surgeon, and 18 healthy controls have also been included in the study. Maternal emotional temperament has been measured with the Temperament Evaluation of Memphis, Pisa, Paris, and San Diego - Auto questionnaire scale, and anxiety sensitivity has been measured with the Anxiety Sensitivity Index-3. RESULTS: There has been no statistically significant difference between groups in terms of maternal emotional temperament and anxiety sensitivity. In the logistic regression analysis conducted to determine the predictors of foreign body aspiration, it is determined that the mother's anxious temperament has predicted foreign body aspiration significantly. CONCLUSION: As a result of the study, it can be concluded that mothers' anxious temperament can be considered a risk factor for foreign body aspiration because it affects parenting skills and children's ability to manage behavioral problems. Consistent results could be able to be obtained with studies including larger samples on the subject.

12.
Thorac Res Pract ; 24(1): 34-39, 2023 Jan.
Article in English | MEDLINE | ID: mdl-37503597

ABSTRACT

OBJECTIVE: External reporting is frequently used due to the significant increase in computed tomography examinations in recent years and the insufficient number of personnel in internal reporting. We aimed to evaluate the adequacy of outsourcing reporting. MATERIAL AND METHODS: Patients who were seen or hospitalized as a consultation by thoracic surgeons with thoracic computed tomography between January 2021 and January 2022 were included in the study retrospectively. Computed tomography results reported by radiologists working in our hospital were grouped as "internal reports," and the results reported externally by a company were grouped as "outsourcing reports." The total number of computed tomography examinations taken during the same period and the number of examinations reported by a daily average radiologist were also determined. False-negative findings in internal and outsourcing reports were evaluated and statistically compared between groups. RESULTS: A total of 84 702 computed tomography scans were taken in 2021. In external reporting, 1 physician reported an average of 202.83 computed tomography scans per day (74 033 per year). A total of 350 thorax computed tomography reports were evaluated. A total of 304 (86.9%) thorax computed tomography examinations were reported with external reporting and 46 (13.1%) with internal reporting. False-negative findings other than those reported were found in 81 reports (23.1%). A significantly higher deficiency was observed in external reporting (77/304) compared to internal reporting (4/46). (P = .013). CONCLUSION: The effectiveness of external reporting was found to be lower than internal reporting due to a possible lack of communication and audit problems. In order to minimize the errors and related liability arising from external reporting, primarily a legal standardization is required with realistic reporting numbers of external reporting.

13.
Environ Sci Pollut Res Int ; 30(30): 75273-75280, 2023 Jun.
Article in English | MEDLINE | ID: mdl-37211569

ABSTRACT

Urban heat island density and occurrence are closely related to land use/land cover and land surface temperature variation. The effect of UHI can be described quantitatively with the urban thermal area variance index. This study aims to evaluate the UHI effect of the city of Samsun with the UTFVI index. LST data from 2000 ETM + and 2020 OLI/TIRS Landsat images were used to analyze UHI. The results showed that the UHI effect increased in Samsun's coastline band in 20 years. As a result of the field analysis made from the UTFVI maps created, in 20 years, 84% decrease in the none slice, 104% increase in the weak slice, 10% decrease in the middle slice, 15% decrease in the strong slice, 8% increase in the stronger slice, and 179% increase in the strongest slice are observed. The slice with the most intense increase is in the strongest slice and reveals the UHI effect.


Subject(s)
Hot Temperature , Urbanization , Cities , Climate Change , Environmental Monitoring/methods , Temperature
14.
J Spec Oper Med ; 23(3): 13-17, 2023 Oct 05.
Article in English | MEDLINE | ID: mdl-37169529

ABSTRACT

BACKGROUND: Today, asymmetric conflict and terrorism pose a threat to not only soldiers but also civilians, forcing the North Atlantic Treaty Organization (NATO) to confront new threats and rethink its strategy. Various studies have shown that telemedicine is one of these advancements and that it can eventually bring expert advice to the field. Telemedicine, on the other hand, is new in Turkey and has yet to be implemented in the field. The aim of this study is to evaluate the support of health personnel with telemedicine from the perspective of military physicians. METHODS: This study was carried out between 20 August 2021 and 5 October 2021 with the participation of 47 military physicians working as research assistants in a training and research hospital. A questionnaire consisting of 17 questions was used to evaluate military physicians' perspectives on telemedicine and their expectations from it. RESULTS: Forty-six of the participants stated that they wanted a healthcare provider/expert opinion to consult about the patient/injured while they were on field and that telemedicine could be used within the scope of field medicine (4.51 ± 0.62). They also stated that telemedicine centers should employ emergency medicine specialists in particular (n = 40, 85.1%). The participants agreed that these centers would be quite useful, particularly for medical evacuations (n = 42, 89.4%). CONCLUSION: Telemedicine's long-term viability in our country is thought to be contingent upon it covering medical conditions that are practical, require fewer technical intricacies, and appeal to emergency health services. The openness of the personnel to innovation and change is expected to improve harmony and cooperation.

15.
Thorac Cardiovasc Surg ; 71(6): 497-503, 2023 09.
Article in English | MEDLINE | ID: mdl-36736368

ABSTRACT

BACKGROUND: Complexities in TNM staging in epithelioid malignant pleural mesothelioma (MPM) may lead to errors in treatment selection, leading to major surgical interventions in patients with low survival expectations. METHODS: Sixty-nine stage I epithelioid MPM patients, including 27 patients treated with pleurectomy/decortication (P/D) and multimodal therapy (MMT) (the P/D [MMT] group), and 42 patients treated with chemotherapy or chemoradiotherapy (the CRT group), were included in the study. After an initial evaluation of overall survival, all patients were grouped in terms of histopathological parameters and treatment types, and then, a secondary survival evaluation was performed for the groups. RESULTS: Forty-one patients were male, the mean age was 61.8 years. The median survival time was 26 months in the P/D (MMT) group, and 19.6 months in the CRT group, but the difference was not statistically significant. After grouping according to pathological criteria, a median survival time of 32.4 ± 2.9 months in the P/D (MMT) group and 21.9 ± 3.2 months in the CRT group was obtained among patients with histopathological low-grade tumors. Among patients with high-grade tumors, the median survival time was 18.3 ± 2.6 months in the P/D (MMT) group and 17 ± 4.4 months in the CRT group. Among patients with low-grade tumors, the P/D (MMT) group had longer survival. Median survival times were similar among patients with high-grade tumors. CONCLUSION: In epithelioid MPM, histopathological grading by video-assisted thoracic surgery pleural biopsy can prove accurate in selecting patients for P/D and MMT.


Subject(s)
Lung Neoplasms , Mesothelioma, Malignant , Mesothelioma , Pleural Neoplasms , Humans , Male , Middle Aged , Female , Mesothelioma/pathology , Mesothelioma/therapy , Patient Selection , Lung Neoplasms/surgery , Treatment Outcome
16.
J Therm Biol ; 112: 103434, 2023 Feb.
Article in English | MEDLINE | ID: mdl-36796891

ABSTRACT

It is inevitable that the global climate change, which has important effects on the climate throughout the world, would have significant effects on the biocomfort zones. Hence, how global climate change will change the biocomfort zones should be determined and the data to be obtained should be used in urban planning projects. In the current study, SSPs 245 and SSPs 585 scenarios were taken as a basis, and the potential effects of global climate change on the biocomfort zones in Mugla province, Türkiye were investigated. Within the scope of the present study, the current status of biocomfort zones in Mugla and their possible conditions in years 2040, 2060, 2080, and 2100 were compared using DI and ETv methods. At the end of the study, it was estimated that, according DI method, 14.13% of Mugla province are in cold zone, 31.96% in cool zone, and 53.71% in comfortable zone. According to the SSPs 585 scenario, together with the increase in temperature, the cold and cool zones will totally disappear in year 2100, comfortable zones will decrease to 31.22%, and approx. 68.78% of the province will be in hot zone. According to the calculations made using ETv method, Mugla province currently consists of moderately cold zones by 2%, quite cold zones by 13.16%, slightly cold zones by 57.06%, and mild zones by 27.79%. Based on the SSPs 585 scenario for the year 2100, it is projected that Mugla will consist of slightly cool zones by 1.41%, mild zones by 14.42%, and comfortable zones by 68.06%, besides warm zones by 16.11% which are not present at this moment. This finding suggests that especially the cooling costs will increase and the air-conditioning systems to be used will negatively affect the global climate change through the energy consumption and the gases used.


Subject(s)
Climate Change , Cold Temperature , Temperature , Seasons
17.
Surg Endosc ; 37(1): 471-478, 2023 01.
Article in English | MEDLINE | ID: mdl-35999314

ABSTRACT

BACKGROUND: Biliary cannulation can be challenging even for expert endoscopists, and rescue techniques are limited. Our objective was to determine the feasibility and safety of partial ampullary endoscopic mucosal resection (PA-EMR), a novel technique for biliary cannulation. METHODS: Monocentric, retrospective analysis of a prospectively maintained database in a tertiary referral university hospital. Fourteen patients who required endoscopic retrograde cholangiopancreatography (ERCP) and underwent PA-EMR between January 1, 2020 and January 31, 2021 were included. For biliary cannulation of prominent papillae, PA-EMR was performed using a standard polypectomy snare, alone or in combination with needle-knife sphincterotomy. In patients with non-prominent papilla, the papillary mucosa was elevated with the aid of methylene blue injection before resection and combined with needle-knife fistulotomy when needed. The rate of technical success and adverse events was assessed. RESULTS: The bile duct cannulation success was 99% in the first attempt and 100% overall with the PA-EMR technique. Only one patient experienced mild bleeding, which spontaneously stopped. CONCLUSION: PA-EMR is an effective technique that may be considered as a rescue technique for difficult biliary cannulation in expert hands. Future studies including larger cohorts and comparisons with other techniques are warranted to further confirm the feasibility and safety of this novel technique.


Subject(s)
Endoscopic Mucosal Resection , Sphincterotomy, Endoscopic , Humans , Sphincterotomy, Endoscopic/methods , Retrospective Studies , Feasibility Studies , Treatment Outcome , Catheterization/methods , Cholangiopancreatography, Endoscopic Retrograde/methods
18.
Environ Sci Pollut Res Int ; 30(11): 29180-29189, 2023 Mar.
Article in English | MEDLINE | ID: mdl-36409417

ABSTRACT

Urbanization, which is defined as an irreversible global-scale problem nowadays, necessitates the foundation of new settlement areas. In general, no sufficient scientific assessment and analysis were performed during these processes, and thus, various natural disasters cost the loss of many lives and properties every year. Nevertheless, considering the areas that are risky in terms of natural disasters during the selection of settlement areas might prevent a large-scale loss of lives and properties because of natural disasters. Within the scope of this study, it was aimed to determine suitable settlement areas in the Alanya district, which is one of the significant points of interest for tourists in our country and has a large population and new settlement areas because of this increasing population. Within this scope, besides the risks of flood and landslide that are the most important natural disasters in the region, and a forest fire that is among the most significant risks for the region, also the biocomfort zones were included in the assessments. As a result of the study, it was determined that the most important natural disaster risk was flooding in a large portion of the region and that only 6.72% of the study area was suitable for settlement in terms of all the criteria examined in the present study.


Subject(s)
Disasters , Landslides , Disasters/prevention & control , Geographic Information Systems , Floods , Urbanization
19.
Anxiety Stress Coping ; 36(1): 38-51, 2023 Jan.
Article in English | MEDLINE | ID: mdl-36288403

ABSTRACT

BACKGROUND AND OBJECTIVES: The adverse effects of the COVID-19 pandemic both necessitate and obstruct emotional regulation and coping mechanisms. Despite growing interest in the connection between stress and spirituality, multilevel studies addressing day-level variance to understand how spiritual experiences and emotional regulation are linked with stress during this unique situation are scarce. This study aims to analyze how daily spiritual experiences (DSE) and daily emotional labor (EL) connect with the daily stress levels of employees during the pandemic. DESIGN AND METHOD: Data collected from 132 employees for five consecutive workdays (660 d-level, 132 person-level responses) were analyzed via Hierarchical Linear Modeling. RESULTS: Multilevel analysis provided evidence for the negative association between DSE and daily stress. The "faking emotions" and "hiding emotions" dimensions of daily EL were positively and significantly related to daily stress, while the "deep acting" dimension demonstrated no significant relationship. There was no evidence for the moderator role of DSE in the relationship between daily EL and stress. CONCLUSION: The form of daily EL is crucial to understanding how it associates with daily stress. Although its buffering role on the adverse effects of EL is not significant, DSE directly relates to lower stress levels.


Subject(s)
COVID-19 , Pandemics , Humans , Multilevel Analysis , Emotions , Adaptation, Psychological
20.
Environ Sci Pollut Res Int ; 30(7): 18748-18754, 2023 Feb.
Article in English | MEDLINE | ID: mdl-36219289

ABSTRACT

Today, most of people's time is spent indoors. Air pollution indoors is much higher than outdoors. Therefore, the effect of indoor air on human health is much more than the outside air. One of the most effective methods of reducing indoor air pollution is the use of plants. However, in order for the plants to be used effectively for this purpose, it is first necessary to determine which plants are the most effective in reducing which pollutants. Within the scope of this study, the Al accumulation potential of seven ornamental plants, which are frequently used in interior architectural designs, was evaluated. Within the scope of the study, the variation of Al concentrations on the basis of species and environment was determined in plants grown in control, smoking environment, and traffic environment. As a result of the study, it was determined that Al concentrations changed statistically significantly both on the basis of environment and species, and the species with the highest Al accumulation potential was difenbahya.


Subject(s)
Air Pollutants , Air Pollution, Indoor , Air Pollution , Environmental Pollutants , Humans , Air Pollutants/analysis , Air Pollution/analysis , Air Pollution, Indoor/analysis , Plants , Environmental Monitoring
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