ABSTRACT
Os autores apresentam uma revisäo da literatura recente sobre a síndrome metabólica mionefropática associada à oclusäo arterial aguda, que inclui sua epidemiologia, aspectos clínicos, diagnóstico e tratamento. Trata-se de um tema ainda pouco divulgado em nosso meio, apesar de sua grande morbimortalidade, sendo, muitas vezes, subdiagnosticado pela freqüente associaçäo com outras doenças cardiovasculares.
Subject(s)
Humans , Arterial Occlusive Diseases/complications , Rhabdomyolysis/etiology , Acute Disease , Arterial Occlusive Diseases/physiopathology , Arterial Occlusive Diseases/therapy , Prognosis , Rhabdomyolysis/physiopathology , Rhabdomyolysis/therapyABSTRACT
A persistência do canal arterial ocorre com freqüência em neonatos prematuros, provocando um grave quadro de disfunçao cardiopulmonar. O tratamento envolve duas abordagens, sendo uma clínica e outra cirúrgica. A operaçao para a ligadura do canal arterial é praticada desde 1938. O enfoque clínico preconiza o uso da indometacina, com o intuito de promover a oclusao do canal arterial. O presente trabalho tem por objetivo avaliar os resultados obtidos com o tratamento cirúrgico da persistência do canal arterial, através de toracotomia e ligadura em 14 pacientes, incluindo crianças de baixo peso e neonatos prematuros com quadro clínico instável. A principal indicaçao cirúrgica, nestes casos, foi a presença de insuficiência respiratória aguda e insuficiência cardíaca. A técnica empregada foi a tripla ligadura do canal arterial. Nos 14 casos nao obtivemos nenhum tipo de complicaçao e sem mortalidade. A presença de uma Unidade de Tratamento Intensivo Neonatal (U.T.I) no Hospital foi de extremo valor no preparo dos pacientes e na evoluçao no período de pós-operatório. Este trabalho comprova a eficácia do método cirúrgico empregado, com baixas taxas de morbidade e mortalidade e a importância da U.T.I neonatal no acompanhamento dos pacientes.
Subject(s)
Humans , Male , Female , Infant, Newborn , Infant , Child, Preschool , Cardiac Output, Low/surgery , Infant, Premature, Diseases/surgery , Ductus Arteriosus, Patent/surgery , Infant, Low Birth Weight , Respiratory Insufficiency/surgery , Intensive Care Units, Neonatal , Intubation , Length of StaySubject(s)
Humans , Female , Adult , Arteriovenous Fistula/diagnosis , Pulmonary Artery , Pulmonary Veins , Arteriovenous Fistula/surgerySubject(s)
Humans , Child, Preschool , Child , Adolescent , Adult , Middle Aged , Myocardium , Heart Arrest, Induced , PotassiumABSTRACT
Thirteen patients were submitted to direct myocardial revascularization (saphenous vein graft) without the use of an artificial oxygenator. The perfusion was done by a left ventricle-to-aorta bypass and autogenous oxygenation. Most patients had three grafts implanted plus endarterectomy of the distal right coronary artery. There was one hospital death that was apparently not related to the method used. Perfusion time ranged from 45 minutes to 4 hours. Body temperature during perfusion was kept between 25 and 30 degrees C. Perfusion flow was maintained between 25 to 50 ml per kg of body weight per minute. Ischemic, hypothermic cardiac arrest was employed. We demonstrated for the first time that perfusion for this kind of heart surgery could be done with no artificial oxygenators and, apparently, is safer for the patients. There were no bleeding problems even in perfusions as long as 4 hours. There was no respiratory dysfunction, and artificial respiration was used for only 6 to 12 hours. The patients awoke at the end of surgery with no signs or symptoms of central nervous system damage, and vasopressor drugs were rarely used after surgery. Although the experience is very small, it suggests that many postoperative problems, especially those related to bleeding and respiratory dysfunction may be reduced or eliminated by this new method.