Primary pure squamous cell carcinoma of the breast diagnosed by fine-needle aspiration cytology: a case study using liquid-based cytology.

Pure primary squamous cell carcinoma (SCC) is an extremely rare type of breast tumor. We report one of such cases in a 32-year-old woman, diagnosed by fine-needle aspiration cytology (FNAC). Aspiration smears were characterized by squamous cells, both isolated and in aggregates, at various stages of maturation. The tumor was excised, and the histologic sections confirmed the cytologic diagnosis. Pure primary SCC of the breast has a distinctive cytomorphologic appearance, and diagnosis of this tumor by FNAC is possible. For its diagnosis, the exclusion of SCC of local cutaneous structures and metastasis of distant squamous carcinoma are mandatory.

[Resolution of Ménétrier's disease after eradication of Helicobacter pylori infection]. / Resolución de la enfermedad de Ménétrier tras la erradicación de la infección por Helicobacter pylori.

Ménétrier's disease is an infrequent clinical entity characterized by thickening of the gastric folds secondary to hyperplasia of the foveolar mucosa cells, frequently associated with loss of enteric proteins and hypoalbuminemia. Its etiology is unknown, although in the last few years it has been related to Helicobacter pylori infection. We present the case of a 38-year-old man with protein-losing gastroenteropathy caused by Ménétrier's disease, in whom eradication of H. pylori infection was followed by symptom improvement and resolution of hypoalbuminemia. In agreement with the criteria of other authors, we investigate the presence of H. pylori infection in all patients with Ménétrier's disease. When positive, the first-line treatment consists of eradication therapy.

Malignant retroperitoneal paraganglioma with intranuclear vacuoles in a fine needle aspirate. A case report.

The cytologic findings in fine needle aspiration smears and cell blocks from a malignant retroperitoneal paraganglioma with subsequent histologic confirmation are described. The aspirate contained clusters of cells with ill-defined borders, often varied in size, round or oval nuclei and marked anisokaryosis. An unusual feature was the presence of prominent intranuclear vacuoles in some cells. The histologic and ultrastructural findings, as well as the results of histochemical and immunodiagnostic staining, are also presented.

[Rhinoscleroma. A case report with nasal and laryngeal involvement]. / Rinoescleroma. Presentación de un caso con afectación nasal y laríngea.

We present a case of rhinoscleroma that were studied in a spanish patient. The location was nasal and extranasal, appearing in the larynx. The diagnosis was established by the morphological picture. A review is given of the geographical distribution of this disease and the principal diagnostic procedures are outlined with special emphasis ou the most reliable staining methods (PAS, Gram), immunofluorescence, immunoperoxydase reactions and electron microscopic study are discussed.

[Melanoma of female distal urethra: apropos of a case]. / Melanoma de uretra distal femenina: a propósito de un caso.

A case is presented of melanoma located at the distal urethra in a 74-year-old patient who underwent local surgery. At present the survival rate is 5 years and local relapse and metastases of one inguinal ganglion has been observed. The different clinical, diagnostic and therapeutic aspects of this neoplasia are discussed.