Subject(s)
Antirheumatic Agents , Arthritis, Psoriatic , Humans , Certolizumab Pegol/adverse effects , Arthritis, Psoriatic/drug therapy , Antirheumatic Agents/therapeutic use , Alopecia/chemically induced , Alopecia/diagnosis , Alopecia/drug therapy , Polyethylene Glycols/therapeutic use , Treatment OutcomeSubject(s)
Exanthema , Lymphoma , Male , Humans , Testis , Exanthema/diagnosis , Exanthema/etiology , Diagnostic ErrorsABSTRACT
Acne fulminans (AF) is a rare, acute, and severe form of acne vulgaris often associated with systemic symptoms. Its treatment is challenging and controversial. We report a case of isotretinoin-induced AF (IIAF) in a 12-year-old boy resistant to traditional therapies (oral steroids and isotretinoin). The patient was successfully treated with adalimumab that can be considered an effective off-label option in the treatment of resistant IIAF in children.
Subject(s)
Acne Vulgaris/therapy , Coronavirus Infections/prevention & control , Dermatology/organization & administration , Infection Control/standards , Pandemics/prevention & control , Pneumonia, Viral/prevention & control , Telemedicine/organization & administration , Acne Vulgaris/diagnosis , Adolescent , Adult , Betacoronavirus/pathogenicity , COVID-19 , Coronavirus Infections/complications , Coronavirus Infections/epidemiology , Coronavirus Infections/transmission , Dermatology/standards , Dermatology/trends , Female , Humans , Infection Control/organization & administration , Infection Control/trends , Infectious Disease Transmission, Patient-to-Professional/prevention & control , Infectious Disease Transmission, Professional-to-Patient/prevention & control , Male , Office Visits/trends , Pneumonia, Viral/complications , Pneumonia, Viral/epidemiology , Pneumonia, Viral/transmission , SARS-CoV-2 , Severity of Illness Index , Telemedicine/standards , Telemedicine/trends , Waiting Lists , Young AdultABSTRACT
The pathogenic mechanism of hypersensitivity reactions (HSRs) to monoclonal antibodies is not fully understood. HSRs can occur after the first exposure or multiple exposures and include acute infusion reactions induced by cytokine release, besides Type I, Type III, and Type IV reactions.). We reported a case of anaphylactic reaction to certolizumab pegol in a patient affected by psoriatic arthritis and a possible management of this condition.
