ABSTRACT
BACKGROUND: Transient tachypnea of the newborn (TTN) is one of the most common causes of neonatal respiratory distress (RD). However, distinguishing TTN from other causes of RD may be difficult during the first 12:24 h after birth. Lung ultrasonography (LUS) has been successfully utilized in the diagnosis and differential diagnosis of neonatal RD. This study aimed to investigate the diagnostic value of LUS for early diagnosis of TTN as well as differentiate it from other causes of neonatal RD in near and full term Egyptian neonates. METHODS: LUS was performed in 65 near and full term neonates presented with RD within the first 12:24 hours of admission in NICU of Suez Canal University, Ismailia, Egypt. RESULTS: Among the 65 neonates included in the study, 73.8% were diagnosed to have TTN, 18.5% were diagnosed to have pneumonia, 4.6% had meconium aspiration syndrome (MAS) and 3.1% had respiratory distress syndrome (RDS). The Double lung point has 69.6% sensitivity, 100% specificity, 100% PPV and 39.1% NPV for detecting TTN. We have novel data showing a positive correlation between the degree of alveolar-interstitial syndrome (AIS) and the type of oxygen support offered to neonates diagnosed with TTN. CONCLUSION: We found LUS to be a reliable and non-invasive tool for the early diagnosis of TTN and its differentiation from other causes of neonatal RD in near and full term Egyptian neonates.
Subject(s)
Lung/diagnostic imaging , Respiratory Distress Syndrome, Newborn/diagnostic imaging , Transient Tachypnea of the Newborn/diagnostic imaging , Ultrasonography , Diagnosis, Differential , Early Diagnosis , Female , Gestational Age , Humans , Infant, Low Birth Weight , Infant, Newborn , Infant, Premature , Lung/physiopathology , Male , Predictive Value of Tests , Reproducibility of Results , Respiratory Distress Syndrome, Newborn/physiopathology , Transient Tachypnea of the Newborn/physiopathologyABSTRACT
PURPOSE: The aim of this study was to report the MRI findings that can suggest a vaso-occlusive crisis in cases of febrile osseous pain in children suffering from sickle cell disease. MATERIALS AND METHODS: MRI (T1 and T2 weighted sequences and T1 weighted sequence with fat saturation before and after gadolinium injection) was performed in 10 children with sickle cell disease, presenting with febrile osseous pain. The diagnosis of vaso-occlusive crisis was made after fast improvement due to symptomatic treatment and negative bacteriological result. RESULTS: MRI was abnormal in all cases. A multifocal localisation was found in 2 cases. Bone marrow abnormalities were constant. In 10 cases, high T1 and T2 signal and metaphyso-diaphysial lesions were noted. Heterogeneous medullar enhancement with "ink stain" feature was constant. Early periosteal abnormalities were noted in 8 cases with inflammatory or stratified features. Cortical thinning was found in 1 case. Soft tissue abnormalities were observed in 5 cases with inflammatory features in 4. CONCLUSION: Multifocal synchronous localisation, medullar abnormalities resulting from hemoglobin degradation, heterogeneous enhancement, early periosteal abnormalities and associated soft tissues swelling are MRI findings suggesting acute vaso-occlusive disease.
Subject(s)
Anemia, Sickle Cell/complications , Bone Diseases/etiology , Magnetic Resonance Imaging/methods , Adolescent , Anemia, Sickle Cell/physiopathology , Bone Diseases/diagnosis , Bone Marrow Diseases/diagnosis , Bone and Bones/blood supply , Bone and Bones/pathology , Child , Child, Preschool , Contrast Media , Female , Fever/physiopathology , Follow-Up Studies , Gadolinium , Humans , Male , Pain/physiopathology , Periostitis/diagnosis , Vascular Diseases/diagnosis , Vascular Diseases/etiologyABSTRACT
Retroperitoneal bronchogenic cysts are rare and those located in the diaphragm are exceptional. We describe an additional case of bronchogenic cyst of the left crus of diaphragm. Diagnosis of a diaphragmatic lesion was confirmed during laparotomy and complete resection was successful. Final diagnosis was done on pathology.