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1.
Radiographics ; 41(5): 1387-1407, 2021.
Article in English | MEDLINE | ID: mdl-34270355

ABSTRACT

With the expansion in cross-sectional imaging over the past few decades, there has been an increase in the number of incidentally detected renal masses and an increase in the incidence of renal cell carcinomas (RCCs). The complete characterization of an indeterminate renal mass on CT or MR images is challenging, and the authors provide a critical review of the best imaging methods and essential, important, and optional reporting elements used to describe the indeterminate renal mass. While surgical staging remains the standard of care for RCC, the role of renal mass CT or MRI in staging RCC is reviewed, specifically with reference to areas that may be overlooked at imaging such as detection of invasion through the renal capsule or perirenal (Gerota) fascia. Treatment options for localized RCC are expanding, and a multidisciplinary group of experts presents an overview of the role of advanced medical imaging in surgery, percutaneous ablation, transarterial embolization, active surveillance, and stereotactic body radiation therapy. Finally, the arsenal of treatments for advanced renal cancer continues to grow to improve response to therapy while limiting treatment side effects. Imaging findings are important in deciding the best treatment options and to monitor response to therapy. However, evaluating response has increased in complexity. The unique imaging findings associated with antiangiogenic targeted therapy and immunotherapy are discussed. An invited commentary by Remer is available online. Online supplemental material is available for this article. ©RSNA, 2021.


Subject(s)
Carcinoma, Renal Cell , Embolization, Therapeutic , Kidney Neoplasms , Carcinoma, Renal Cell/diagnostic imaging , Carcinoma, Renal Cell/therapy , Humans , Kidney , Kidney Neoplasms/diagnostic imaging , Kidney Neoplasms/therapy , Magnetic Resonance Imaging
2.
Magn Reson Imaging Clin N Am ; 28(3): 447-456, 2020 Aug.
Article in English | MEDLINE | ID: mdl-32624161

ABSTRACT

Add "which is a" before "distribution"? Texture analysis (TA) is a form of radiomics that refers to quantitative measurements of the histogram, distribution and/or relationship of pixel intensities or gray scales within a region of interest on an image. TA can be applied to MR images of the abdomen and pelvis, with the main strength quantitative analysis of pixel intensities and heterogeneity rather than subjective/qualitative analysis. There are multiple limitations of MRTA. Despite these limitations, there is a growing body of literature supporting MRTA. This review discusses application of MRTA to the abdomen and pelvis.


Subject(s)
Digestive System Neoplasms/diagnostic imaging , Endometrial Neoplasms/diagnostic imaging , Kidney Neoplasms/diagnostic imaging , Magnetic Resonance Imaging/methods , Prostatic Neoplasms/diagnostic imaging , Rectal Neoplasms/diagnostic imaging , Abdomen/diagnostic imaging , Female , Humans , Male , Pelvis/diagnostic imaging
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