Subject(s)
Melanoma/pathology , Sentinel Lymph Node Biopsy , Skin Neoplasms/pathology , Aged , Female , Humans , Male , Middle Aged , Predictive Value of Tests , Prognosis , Risk Assessment , TelemedicineSubject(s)
Melanoma/diagnosis , Neck/pathology , Nevus, Sebaceous of Jadassohn/diagnosis , Warts/pathology , Adult , Biopsy , Dermoscopy/methods , Diagnostic Errors , Humans , Keratosis/pathology , Melanocytes/pathology , Melanoma/pathology , Nevus, Sebaceous of Jadassohn/pathology , Papilloma/pathology , Pigmentation Disorders/pathology , Skin Neoplasms/pathology , Skin PigmentationABSTRACT
Functional disorders within dermatology present as various constellations of skin symptoms, but without evidence of organic pathology. Examples can include mucocutaneous pain syndromes, functional pruritus, somatoform pain disorder and rarer entities, such as undifferentiated somatoform idiopathic anaphylaxis and multiple chemical sensitivity syndrome. These conditions can have a significant impact on a patient's quality of life, and can present challenges in communication, investigation and management. The aetiology of functional disorders is not fully understood, but with an effective collaborative approach, a psychological explanation for these symptoms is often found. A structured approach to assessment can lead to a confident diagnosis, and understanding a patient's belief system and the impact of symptoms on their functioning can give better grounding for successful management. Treatment is dependent on the level of the patient's engagement with healthcare professionals, and often takes a measured and rehabilitative approach. Psychological therapies have been shown to be effective, often alongside both psychopharmacological and topical medications.
Subject(s)
Anaphylaxis , Chronic Pain , Environmental Illness , Pruritus , Somatoform Disorders , Anaphylaxis/diagnosis , Anaphylaxis/therapy , Chronic Pain/diagnosis , Chronic Pain/therapy , Environmental Illness/diagnosis , Environmental Illness/therapy , Humans , Pruritus/diagnosis , Pruritus/therapy , Somatoform Disorders/diagnosis , Somatoform Disorders/therapyABSTRACT
Functional - or somatoform - symptoms are those that arise with no proven organic pathology. Also known as 'medically unexplained' symptoms, they can present in any medical speciality, including dermatology. Mucocutaneous pain syndromes and functional pruritus are two examples of functional disorders encountered by dermatologists. Patients presenting with somatoform symptoms have paradoxically complex and often subjectively severe symptomatology, yet minimal abnormalities on clinical examination or investigation. Such disparity can be frustrating and distressing for patients and clinicians alike, and there are many pitfalls regarding overinvestigation and misleading communication. However, with an honest and open approach - sometimes requiring collaboration with psychological services - management of functional symptoms can be effective, and patients can be successfully rehabilitated.
Subject(s)
Chronic Pain , Environmental Illness/psychology , Somatoform Disorders , Anaphylaxis , Chronic Pain/etiology , Chronic Pain/psychology , Humans , Pruritus/diagnosisSubject(s)
Dermatologic Agents/adverse effects , Isotretinoin/adverse effects , Mental Health/statistics & numerical data , Mood Disorders/chemically induced , Acne Vulgaris/drug therapy , Acne Vulgaris/psychology , Depression/chemically induced , Depression/epidemiology , Depression/psychology , Dermatologists/statistics & numerical data , Dermatology/organization & administration , Humans , Mood Disorders/epidemiology , Mood Disorders/psychology , Prevalence , Risk Factors , Scotland/epidemiology , Suicide, Completed/statistics & numerical data , Surveys and QuestionnairesSubject(s)
Idiopathic Pulmonary Fibrosis , Psoriasis , Humans , Immunosuppressive Agents , MethotrexateSubject(s)
Dermatologic Agents/adverse effects , Idiopathic Pulmonary Fibrosis/chemically induced , Methotrexate/adverse effects , Psoriasis/drug therapy , Aged, 80 and over , Dermatologic Agents/administration & dosage , Dermatologic Agents/therapeutic use , Fatal Outcome , Humans , Methotrexate/administration & dosage , Methotrexate/therapeutic useSubject(s)
Antipruritics/administration & dosage , Pruritus/therapy , Administration, Cutaneous , Adult , Aged , Complementary Therapies , Drug Eruptions/complications , Ectoparasitic Infestations/complications , Emotions , Endocrine System Diseases/complications , Forecasting , Hematologic Diseases/complications , Humans , Infections/complications , Iron Deficiencies , Iron Overload/complications , Liver Diseases/complications , Mental Disorders/complications , Neoplasms/complications , Nervous System Diseases/complications , Phototherapy/methods , Primary Health Care , Pruritus/diagnosis , Pruritus/etiology , Uremia/complicationsSubject(s)
Carcinoma, Squamous Cell/etiology , Ear Auricle/pathology , Ear Neoplasms/etiology , Epidermal Cyst/complications , Papillomavirus Infections/complications , Skin Neoplasms/etiology , Aged , Biopsy , Cell Transformation, Neoplastic , Epidermal Cyst/pathology , Epidermal Cyst/virology , Humans , Male , PapillomaviridaeABSTRACT
The incidence, clinical characteristics and management of lentigo maligna (LM) were assessed in a university hospital setting in 2005 and 2014. Multiple clinical variables were compared, and 28 and 43 cases, respectively were identified during the two time periods. The most common site of presentation was the cheek (50% vs. 44%), and an accurate clinical diagnosis of LM was made in 60% vs. 72%) of cases. Most of the patients received surgical treatment (75% in 2005 vs. 97% in 2014), with 47% and 33% of excisions, respectively, remaining involved at the peripheral surgical margin. During the 10-year follow-up for the 2005 cohort, 7 of the 28 patients had recurrence (3 of whom already had previously involved margins following surgery). This study shows that making an accurate clinical diagnosis of LM remains a significant challenge. Although surgery has become the preferred management option, achieving clear excision remains difficult, with involved margins increasing the risk of local recurrence and need for further intervention.