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Filter membrane-based automated therapeutic plasma exchange: a report of two cases from Nigeria.

Arogundade, Fatiu A; Sanusi, Abubakr A; Akinbodewa, Akinwunmi A; Hassan, Muzamil O; Omotosho, Bolanle O; Balogun, Rasheed A; Akinsola, Adewale.

J Clin Apher ; 28(1): 78-83, 2013 Feb.

Article in English | MEDLINE | ID: mdl-23420598

ABSTRACT

These case reports demonstrated the diagnostic dilemma encountered in patients with systemic lupus erythematosus and thrombotic thrombocytopenic purpura particularly in settings with limited diagnostic facilities and laboratory support. The similarities in the diagnostic criteria for both conditions make clear distinction as well as management decisions difficult. We present the difficulties encountered with both the diagnosis and the management of these two patients that were managed in our facility.

Subject(s)

Lupus Erythematosus, Systemic/complications , Plasma Exchange/methods , Puerperal Disorders/therapy , Purpura, Thrombotic Thrombocytopenic/etiology , Acute Kidney Injury/etiology , Acute Kidney Injury/therapy , Adult , Automation , Combined Modality Therapy , Developing Countries , Fatal Outcome , Female , Filtration , Humans , Immunosuppressive Agents/therapeutic use , Lupus Erythematosus, Systemic/diagnosis , Lupus Erythematosus, Systemic/drug therapy , Lupus Nephritis/chemically induced , Lupus Nephritis/drug therapy , Lupus Nephritis/etiology , Lupus Nephritis/therapy , Membranes, Artificial , Nigeria , Phytotherapy/adverse effects , Plasma Exchange/economics , Plasma Exchange/instrumentation , Platelet Transfusion/adverse effects , Pregnancy , Pregnancy Complications/drug therapy , Pregnancy Complications/immunology , Puerperal Disorders/immunology , Purpura, Thrombotic Thrombocytopenic/drug therapy , Purpura, Thrombotic Thrombocytopenic/therapy , Young Adult

ABSTRACT

Subject(s)

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