ABSTRACT
Three cases of a newly described rare odontogenic tumor are reported. One patient died with pulmonary metastases, one had an associated odontogenic cyst and one exhibited regional lymph node metastasis. The cases lend support to the odontogenic origin and metastatic capability of the clear cell odontogenic tumor. The authors recommend aggressive therapy and believe that the tumor should be considered a clear cell odontogenic carcinoma.
Subject(s)
Lung Neoplasms/secondary , Lymphatic Metastasis , Mandibular Neoplasms/pathology , Odontogenic Tumors/pathology , Aged , Aged, 80 and over , Ameloblastoma/pathology , Female , Humans , Immunohistochemistry , Lung Neoplasms/pathology , Male , Middle Aged , Neoplasm Invasiveness , Neoplasm Recurrence, Local , Odontogenic Tumors/secondarySubject(s)
Immobilization , Mandible , Maxilla , Obesity, Morbid/therapy , Obesity/therapy , Adult , Female , Follow-Up Studies , Humans , Male , MethodsABSTRACT
Multiple oral plexiform neuromas in a 14-year-old white girl prompting screening of the patient with respect to the multiple endocrine neoplasia (MEN) type-III syndrome, verified the existence of a thyroid medullary carcinoma and the diagnosis MEN-type III. Total thyroidectomy was performed, but extensive tumour infiltration prevented radical tumour excision. The condition being relatively infrequent, the important life-saving role of dental practitioners and oral surgeons in its recognition and early diagnosis is emphasized.