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1.
APSP J Case Rep ; 5(2): 17, 2014 May.
Article in English | MEDLINE | ID: mdl-25057470

ABSTRACT

Gossypiboma (GP) or retained surgical sponge is one of the rare surgical complications which can happen despite precautions. Because of the medico-legal issues, it is under-reported. An 8-year-old thalassemic girl, with a history of splenectomy and cholecystectomy, presented to us with acute intestinal obstruction and required surgical exploration. Intraluminal gossypiboma obstructing the ileum was found. Though a rare cause, gossypiboma should also be included in the differential diagnoses of postoperative intestinal obstruction.

2.
Indian J Pharmacol ; 45(3): 293-4, 2013.
Article in English | MEDLINE | ID: mdl-23833377

ABSTRACT

Duodenal ulcer perforation in pediatric age group is an uncommon entity; hence, it is not usually considered in the differential diagnosis of acute abdomen in these patients. It is important for the emergency physician to consider perforated peptic ulcer in the differential diagnosis of children presenting with acute abdominal pain, gastrointestinal bleeding, or shock. We report a 6½-year-old male child with thalassemia major who presented to emergency room with an acute abdomen and shock, who was subsequently found to have a perforated duodenal ulcer, probably related to use of oral chelating agent, deferasirox. Although, gastrointestinal symptoms like nausea, vomiting, and abdominal pain has been mentioned as infrequent adverse event in the scientific product information of deferasirox, in our current knowledge this is the first case report of perforated duodenal ulcer after oral deferasirox. The severity of this event justifies the reporting of this case. This patient had an atypical presentation in that there were no signs or symptoms of peptic ulcer disease before perforation and shock he was successfully managed with open surgery after initial resuscitation and stabilization of his general condition.


Subject(s)
Benzoates/adverse effects , Duodenal Ulcer/chemically induced , Iron Chelating Agents/adverse effects , Peptic Ulcer Perforation/chemically induced , Triazoles/adverse effects , Child , Deferasirox , Duodenal Ulcer/diagnosis , Humans , Male , Peptic Ulcer Perforation/diagnosis , beta-Thalassemia/drug therapy
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