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1.
J Pak Med Assoc ; 69(9): 1365-1368, 2019 Sep.
Article in English | MEDLINE | ID: mdl-31511726

ABSTRACT

The oesophagus can be a site for a variety of lesions including inflammatory disorders, infections, mechanical conditions, toxic and physical injuries, vascular disorders and neoplastic conditions. hence the oesophageal diseases have a wide spectrum of pathological features. An understanding of histopathological details of oesophageal diseases is essential for their accurate diagnosis and management. The main objective of our study was to provide a comprehensive audit of oesophageal diseases in the province of Madinah in Saudi Arabia. From January 2006 to December 2017, were viewed the histopathological patterns of oesophageal lesions in patients at a tertiary care referral hospital who were diagnosed with oesophageal disease after upper gastroendoscopy. Of the 201 patients, 144 (71.6%) cases were found to be non-neoplastic and 57 (28.4%) cases were neoplastic. Our findings were comparable with earlier studies that helped establish a baseline of an oesophageal disease pattern, on the basis of histopathological examinations.


Subject(s)
Esophageal Diseases/epidemiology , Adenocarcinoma/epidemiology , Adenocarcinoma/pathology , Adolescent , Adult , Aged , Aged, 80 and over , Barrett Esophagus/epidemiology , Barrett Esophagus/pathology , Candidiasis/epidemiology , Candidiasis/pathology , Carcinoma, Squamous Cell/epidemiology , Carcinoma, Squamous Cell/pathology , Eosinophilic Esophagitis/epidemiology , Eosinophilic Esophagitis/pathology , Esophageal Diseases/pathology , Esophageal Neoplasms/epidemiology , Esophageal Neoplasms/pathology , Esophagitis, Peptic/epidemiology , Esophagitis, Peptic/pathology , Female , Humans , Hyperplasia , Lymphoma/epidemiology , Lymphoma/pathology , Male , Middle Aged , Neuroendocrine Tumors/epidemiology , Neuroendocrine Tumors/pathology , Polyps/epidemiology , Polyps/pathology , Retrospective Studies , Saudi Arabia/epidemiology , Young Adult
2.
J Pak Med Assoc ; 65(7): 785-7, 2015 Jul.
Article in English | MEDLINE | ID: mdl-26160092

ABSTRACT

Metaplastic Breast Carcinoma (MBC) is a group of rare breast cancers; squamous cell carcinoma (SCC) is its most common member. Due to rarity of the condition, frequent case reports have been published of late. In the last one year alone, there were about a dozen such reports. Here we report a case of primary squamous cell carcinomain a 62-year-old female, with a 3.5cm mass in the left breast. Biopsy and mastectomy reports confirmed Metaplastic carcinoma, with 21 benign lymph nodes.. The tumour was triple negative and cytokeratin 5/6 positive. We are reporting the first case of squamous cell carcinoma of breast from our region, and we recommended large multi centre studies.


Subject(s)
Breast Neoplasms/pathology , Carcinoma, Squamous Cell/pathology , Breast Neoplasms/metabolism , Carcinoma, Squamous Cell/metabolism , Female , Humans , Keratins/metabolism , Middle Aged
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