ABSTRACT
BACKGROUND: To evaluate the efficacy of topical ivermectin 1% ointment, for the treatment of Demodex blepharitis. METHODS: A retrospective study was designed to review electronic medical records of patients seen between January 2017 and December 2022, who had a diagnosis of Demodex blepharitis, treated with topical ivermectin 1% with at least 6 months of follow-up (Centro de Ojos Quilmes, Buenos Aires, Argentina). The presence of collarettes was graded from 0 to 4. An imaging system (Keratograph) was used, to evaluate tear meniscus height (TMH), non-invasive tear break-up time (NIKBUT), and degree of conjunctival redness. In addition, the ocular surface disease index (OSDI) test was performed. Results were compared before and after ivermectin treatment, which was performed once a day for 2 months. RESULTS: A total of 2157 patients (4314 eyes) were included. The mean age was 50.43 ± 15.3 years, and the follow-up time was 26.1 ± 8.5 months. No one discontinued treatment due to intolerance, although 14 cases (0.6 %) reported occasional discomfort. The grade of collarettes decreased with statistical significance, from 3.37 ± 0.7 to 0.1 ± 0.3 (p < 0.01), as well as conjunctival redness from 1.32 ± 0.3 to 0.94 ± 0.4 (p < 0.01) and OSDI score from 58.74 ± 17.9 to 17.1 ± 10.5 (p = 0.02). TMH and NIKBUT improved without statistical difference. CONCLUSION: Treatment with ivermectin 1% topical ointment, once daily for 2 months, was effective in reducing the presence of collarettes and in improving symptoms in patients with Demodex blepharitis.
Subject(s)
Blepharitis , Mite Infestations , Humans , Adult , Middle Aged , Aged , Ivermectin , Retrospective Studies , Blepharitis/diagnosis , Blepharitis/drug therapy , Mite Infestations/diagnosis , Mite Infestations/drug therapy , OintmentsABSTRACT
PURPOSE: To review the prevalence and describe the characteristics, of cases with late-onset intracorneal ring segments (ICRS) keratopathy in a multicenter study. METHODS: A retrospective multicentric case-series study was performed in a specialized keratoconus service, from Buenos Aires, Argentina. An electronic clinical chart from patients with ICRS keratopathy between January 1999 and January 2019 was reviewed. We included cases with late-onset distal-apical ICRS keratopathy, which was defined as a persistent corneal lesion developed 12 months or later after implantation, located over, around, or closer to the ICRS. All the surgeries were performed by a manual corneal tunnel creation technique. Samples were taken to rule out infectious etiology. RESULTS: From 5217 eyes that underwent ICRS implantation, 13 cases (0.24%) were detected. The keratopathy onset was 72 ± 42.98 months (29-133) after ICRS implantation. Cultures were negative in all cases. An ICRS exchange was made for five cases in stage I and four in stage II. Four cases presented with partial ICRS extrusion in stage III. ICRS exchange was possible in two of them and a penetration keratoplasty was necessary for the rest. All cases remained stable 1 year after surgical procedures. CONCLUSIONS: A late-onset distal-apical ICRS keratopathy was detected with low prevalence (0.24%) in a large sample. It was classified into three stages according to its severity. Different treatments were selected for each stage, obtaining stable results 1 year after treatment.
Subject(s)
Keratoconus , Prosthesis Implantation , Humans , Prosthesis Implantation/methods , Prostheses and Implants , Retrospective Studies , Corneal Topography , Keratoconus/diagnosis , Keratoconus/epidemiology , Keratoconus/surgery , Eye, Artificial , Corneal Stroma/surgery , Corneal Stroma/pathology , Refraction, OcularABSTRACT
A new technique that allows implanting intracorneal ring-segments (ICRS) from the limbal zone is described. Using a femtosecond laser (FSL), a 360° corneal tunnel is created with an internal diameter of 5.4 mm and an external diameter of 7.0 mm, with a wider area (0.2 mm inner and 0.2 mm outer) in the upper 60° of the tunnel (called landing zone). Next, a 4.36 mm-long corneal-limbal incision was created with the FSL, which connects to the bubbles created in the landing zone. The entire procedure was performed using intraoperative optical coherence tomography (OCT). Once the two incisions were connected using blunt-edged Mac Pherson forceps, the bubbles were released from the surgical plane. The programmed ICRS(s), 6 mm in diameter, are then placed in the corneal tunnel from the limbal incision with the aid of Sinskey forceps. Finally, when the ICRS is in place, the surgery is complete.
ABSTRACT
Objetivo: avaliar o estágio atual da cirurgia refrativa na América Latina. Material e método: questionário analisando aspectos demográficos de cada país, técnicas realizadas, custo de equipamentos e preços cobrados por serviços säo estudados. Também säo analisadas as sugestöes e críticas ao estado atual da cirurgia refrativa em diferentes regiöes. Os questionários foram respondidos pelos representantes da International Society of Refractive Surgery. A data de término da pesquisa foi de 30/03/97. Resultados: Duas centenas de Excimer Lasers funcionam na América Latina. Os preços dos serviços variam de 200 a 2200 USD com variaçöes regionais. Queixas como comportamento antiético, alto preço dos equipamentos e baixo preço dos serviços se constituem nos ..
Subject(s)
Humans , Laser Therapy/trends , Latin AmericaABSTRACT
Se ha realizado una búsqueda bibliográfica de todos los estudios biométricos normales y patológicos de 0 a 14 años publicados hasta la fecha, para evaluar y correlacionar los resultados entre los pacientes normales y los portadores de Glaucoma Congénito. Pudiéndose demostrar las diferentes respuestas de estas ante condiciones patológicas y cuáles son los cambios observados de mayor significado clínico
Subject(s)
Biometry/methods , Eye/anatomy & histology , Glaucoma/congenital , Ultrasonography , Glaucoma/diagnosisABSTRACT
Se ha realizado una búsqueda bibliográfica de todos los estudios biométricos normales y patológicos de 0 a 14 años publicados hasta la fecha, para evaluar y correlacionar los resultados entre los pacientes normales y los portadores de Glaucoma Congénito. Pudiéndose demostrar las diferentes respuestas de estas ante condiciones patológicas y cuáles son los cambios observados de mayor significado clínico (AU)
