Search | VHL Regional Portal

1.

[The influence of beta-blockers on glycogen metabolism in the rat liver in physical exercise (author's transl)]. / Der Effekt von beta-Rezeptorenblockern auf den Glykogenstoffwechsel der Rattenleber unter körperlicher Belastung.

Kindler, J; Clasing, D; Alfes, H; Schulz, V.

Arzneimittelforschung ; 28(8): 1376-81, 1978.

Article in German | MEDLINE | ID: mdl-37854

Subject(s)

Adrenergic beta-Antagonists/pharmacology , Liver Glycogen/metabolism , Liver/metabolism , Physical Exertion , Animals , Female , Liver/anatomy & histology , Liver/drug effects , Rats , Time Factors

2.

The biogenic amines in the carotid body.

Alfes, H; Kindler, J; Knoche, H; Matthiessen, D; Möllmann, H; Pagnucco, R.

Prog Histochem Cytochem ; 10(2): 1-69, 1977.

Article in English | MEDLINE | ID: mdl-341223

Subject(s)

Biogenic Amines/metabolism , Carotid Body/metabolism , Adrenal Medulla/metabolism , Adrenal Medulla/ultrastructure , Animals , Biogenic Amines/analysis , Carotid Body/analysis , Carotid Body/ultrastructure , Cats , Cytoplasmic Granules/metabolism , Horses , Male , Nitrogen Fixation , Rabbits , Vacuoles/ultrastructure

3.

Electron microscopic autoradiographic localization of carbocromene in the coronary vessel walls and myocardium.

Alfes, H; Mölmann, H; Bigalke, C; Nitz, R E; Ostrowski, J; Schraven, E; Kindler, J.

Basic Res Cardiol ; 70(1): 58-64, 1975.

Article in English | MEDLINE | ID: mdl-1122219

ABSTRACT

The ultrastructural distribution of 14-C- and the 3-H-carbocromene in monkeys and rats showed a characteristic pattern in the coronary artery wall and the heart muscle. The radioactivity was found to be located on the coronary vessel wall mainly in the tunica media over the smooth muscle cells and in the myocardium over the contractile elements and the mitochondria.

Subject(s)

Coronary Vessels/metabolism , Coumarins/metabolism , Glycolates/metabolism , Myocardium/metabolism , Administration, Oral , Animals , Autoradiography , Carbon Radioisotopes , Coronary Vessels/ultrastructure , Heart Atria , Heart Ventricles , Injections, Intravenous , Male , Microradiography , Microscopy, Electron , Mitochondria, Muscle/metabolism , Myocardium/ultrastructure , Myofibrils/metabolism , Rats , Sarcoplasmic Reticulum/metabolism , Tritium

4.

[Distribution of 14C-carbocromen in the monkey brain]. / Verteilung von 14C- carbocromen im affenhirn

Bigalke, C; Möllmann, H; Kuckuck, L; Kindler, J; Alfes, H; Schraven, E; Nitz, R E.

Arzneimittelforschung ; 24(5): 765-81, 1974 May.

Article in German | MEDLINE | ID: mdl-4211395

Subject(s)

Brain/metabolism , Coumarins/metabolism , Animals , Autoradiography , Brain Chemistry , Brain Mapping , Carbon Radioisotopes , Cerebellum/analysis , Coumarins/analysis , Densitometry , Diencephalon/analysis , Diethylamines/analysis , Diethylamines/metabolism , Glycolates/analysis , Glycolates/metabolism , Haplorhini , Limbic System/analysis , Macaca , Medulla Oblongata/analysis , Mesencephalon/analysis , Microscopy, Electron , Occipital Lobe/analysis , Parietal Lobe/analysis , Rats , Telencephalon/analysis , Time Factors

5.

[Site of action of the coronary medication, carbochromen]. / Une contribution a l'etude du point d'action du medicament coronaire, le carbochromene

Alfes, H; Schraven, E; Möllmann, H; Ostrowski, J; Bigalke, G; Nitz, R E.

Brux Med ; 54(5): 303-8, 1974 May.

Article in French | MEDLINE | ID: mdl-4214587

Subject(s)

Coumarins/pharmacology , Glycolates/pharmacology , Myocardium/metabolism , Animals , Autoradiography , Carbon Radioisotopes , Chemical Phenomena , Chemistry , Coronary Disease/drug therapy , Coumarins/metabolism , Glycolates/metabolism , Haplorhini , In Vitro Techniques , Isotope Labeling , Rats , Spectrophotometry , Time Factors , Vasodilator Agents

6.

[Site of action of the coronary drug carbocromen]. / Ein Beitrag zum Angriffspunkt des Koronartherapeutikums Carbocromen.

Alfes, H; Schraven, E; Möllmann, H; Ostrowski, J; Bigalke, G; Nitz, R E.

Fortschr Med ; 91(19): 837-43, 1973 Jul 05.

Article in German | MEDLINE | ID: mdl-4198875

Subject(s)

Coumarins/pharmacology , Heart/drug effects , Vasodilator Agents/pharmacology , Animals , Autoradiography , Coronary Circulation/drug effects , Coronary Vessels/drug effects , Coumarins/metabolism , Ethylamines/metabolism , Ethylamines/pharmacology , Glycolates/metabolism , Glycolates/pharmacology , Glycolysis/drug effects , Haplorhini , Myocardium/metabolism , Vasodilator Agents/metabolism

7.

[Influence of synthetic glucocorticoids and of metopirone on ketosteroid-containing cells of the postnatal rabbit thymus (author's transl)]. / Einfluss von synthetischen glucocorticoiden und von metopiron auf ketosteroidhaltige zellen des postnatalen kaninchenthymus.

Henning, W; Möllmann, H; Kindler, J; Reisch, J; Alfes, H.

Z Zellforsch Mikrosk Anat ; 143(1): 37-44, 1973.

Article in German | MEDLINE | ID: mdl-4788141

Subject(s)

Glucocorticoids/pharmacology , Metyrapone/pharmacology , Thymus Gland/drug effects , Adrenalectomy , Age Factors , Animals , Animals, Newborn , Betamethasone/pharmacology , Body Weight , Glucocorticoids/administration & dosage , Glucocorticoids/metabolism , Hydrocortisone/pharmacology , Injections, Intramuscular , Injections, Intraperitoneal , Ketosteroids/metabolism , Methods , Metyrapone/administration & dosage , Organ Size , Rabbits , Splenectomy , Thymectomy , Thymus Gland/growth & development , Thymus Gland/metabolism

8.

[Topochemical demonstration of carbonyl compounds in the thymus (author's transl)]. / Topochemischer Nachweis von carbonylhaltigen Verbindungen im Thymus.

Möllmann, H; Henning, W; Reisch, J; Kindler, J; Alfes, H.

Z Zellforsch Mikrosk Anat ; 142(4): 465-77, 1973.

Article in German | MEDLINE | ID: mdl-4128964

Subject(s)

Ketosteroids/analysis , Thymus Gland/analysis , Animals , Connective Tissue , Fluorescence , Histocytochemistry , Mast Cells , Methods , Microscopy, Electron , Rabbits , Staining and Labeling

9.

[Pharmacodynamic studies after short- and long-term treatment with radioactively labelled 3-(beta-diethylamino-ethyl)-4-methyl-7-carbethoxy-2-oxo-(1,2-chromene)-hydrochloride in animal experiments]. / Pharmakodynamische Untersuchungen nach Kurz- und Langzeit-Behandlung mit radioaktiv markiertem 3-(beta-Diäthylamino-äthyl)-4-methyl-7-carbäthoxy-methoxy-2-oxo-(1,2-chromen)-hydrochlorid im Tierexperiment.

Möllmann, H; Alfes, H; Schraven, E; Ostrowski, J; Nitz, R E; Bigalke, C.

Arzneimittelforschung ; 22(8): 1242-50, 1972 Aug.

Article in German | MEDLINE | ID: mdl-4629173

Subject(s)

Coumarins/metabolism , Glycolates/metabolism , Administration, Oral , Animals , Carbon Isotopes , Coumarins/administration & dosage , Coumarins/urine , Feces/analysis , Female , Fetus/metabolism , Glycolates/administration & dosage , Glycolates/urine , Half-Life , Injections, Intraperitoneal , Intestinal Absorption , Male , Mice , Myocardium/metabolism , Pregnancy , Pregnancy, Animal , Rats , Time Factors , Whole-Body Counting

10.

[Studies on the distribution of carbochromen- 14 C in rats. Organ distribution and whole-body autoradiography after i.v. administration]. / Untersuchungen zur Verteilung von 14 C-carbochromen bei Ratten. Verteilung in den Organen und Ganztier-Autoradiographie nach i.v. Applikation.

Schraven, E; Möllmann, H; Nitz, R E; Alfes, H.

Arzneimittelforschung ; 22(3): 479-87, 1972 Mar.

Article in German | MEDLINE | ID: mdl-5067914

Subject(s)

Coumarins/metabolism , Vasodilator Agents/metabolism , Animals , Autoradiography , Brain/metabolism , Carbon Isotopes , Ethylamines/metabolism , Glycolates/metabolism , Kidney/metabolism , Liver/metabolism , Lung/metabolism , Male , Myocardium/metabolism , Rats , Time Factors

11.

[Ultrastructural distribution of 14 C- and 3 H-labelled carbocromen in the heart]. / Die ultrastrukturelle Verteilung von 14 C- und 3 H-markiertem Carbochromen im Herzen.

Möllmann, H; Schraven, E; Alfes, H; Nitz, R E.

Arzneimittelforschung ; 22(3): 487-92, 1972 Mar.

Article in German | MEDLINE | ID: mdl-5067915

Subject(s)

Coumarins/metabolism , Myocardium/metabolism , Vasodilator Agents/metabolism , Animals , Autoradiography , Carbon Isotopes , Ethylamines/metabolism , Glycolates/metabolism , Injections, Intravenous , Microscopy, Electron , Mitochondria/metabolism , Myofibrils/metabolism , Rats , Tritium

12.

[Absorption and distribution of carbocromen- 14 C in the central nervous system of the rat]. / Aufnahme und Verteilung von Carbochromen- 14 C im Zentralnervensystem der Ratte.

Möllmann, H; Schraven, E; Warntjen, H; Nitz, R E; Alfes, H.

Arzneimittelforschung ; 22(3): 492-502, 1972 Mar.

Article in German | MEDLINE | ID: mdl-5067916

Subject(s)

Central Nervous System/metabolism , Coumarins/metabolism , Vasodilator Agents/metabolism , Amygdala/metabolism , Animals , Autoradiography , Basal Ganglia/metabolism , Brain/metabolism , Carbon Isotopes , Cerebral Cortex/metabolism , Ethylamines/metabolism , Glycolates/metabolism , Hippocampus/metabolism , Rats , Septal Nuclei/metabolism , Spinal Cord/metabolism , Thalamus/metabolism

13.

[Comparative studies on grain size distribution and nature of particles of some corticoid crystal suspensions]. / Vergleichende Untersuchungen der Korngrössenverteilung und Partidelbeschaffenheit einiger Coricoid-Kristallsuspensionen.

Möllmann, H; von Klot-Heydenfeldt, B; Niemeyer, D H; Alfes, H.

Int Z Klin Pharmakol Ther Toxikol ; 5(4): 434-43, 1972 Feb.

Article in German | MEDLINE | ID: mdl-5046054

Subject(s)

Adrenal Cortex Hormones , Crystallography , Delayed-Action Preparations , Acetates , Betamethasone , Chemistry, Organic , Methylprednisolone , Microscopy, Electron, Scanning , Microscopy, Polarization , Optics and Photonics , Organic Chemistry Phenomena , Prednisolone , Suspensions , Triamcinolone , Triamcinolone Acetonide , Weights and Measures , X-Ray Diffraction

14.

[Electron microscopic and fluorescence microscopic studies of biogenic amines in the rabbit glomus caroticum after treatment with reserpine and PCPA]. / Experimenteller Beitrag zur Kenntnis der biogenen amine im glomus caroticum des Kaninchens. Elektronen- und fluoreszenzmikroskopische Untersuchungen nach Reserpin- und PCPA-Applikation.

Möllmann, H; Knoche, H; Niemeyer, D H; Alfes, H; Kienecker, E W; Decker, S.

Z Zellforsch Mikrosk Anat ; 124(2): 238-46, 1972.

Article in German | MEDLINE | ID: mdl-4258968

Subject(s)

Amines , Carotid Body/analysis , Animals , Axons/cytology , Biogenic Amines/analysis , Carotid Body/cytology , Carotid Body/drug effects , Catecholamines , Chemoreceptor Cells/cytology , Cytoplasmic Granules , Fenclonine/pharmacology , Fluorescence , Indoles , Male , Microscopy, Electron , Microscopy, Fluorescence , Mitochondria , Rabbits , Reserpine/pharmacology , Serotonin

15.

[Microspectrofluorometric studies of biogenic amines in the rabbit glomus caroticum after reserpine and PCPA treatment]. / Mikrospektrofluorometrische Untersuchungen der biogenen Amine im Glomus caroticum des Kaninchens nach Reserpin- und PCPA-Applikation.

Möllmann, H; Niemeyer, D H; Alfes, H; Knoche, H.

Z Zellforsch Mikrosk Anat ; 126(1): 104-15, 1972.

Article in German | MEDLINE | ID: mdl-4259704

Subject(s)

Amines/analysis , Carotid Body/analysis , Animals , Biogenic Amines/analysis , Catecholamines , Fenclonine/administration & dosage , Fluorescence , Fluorometry , Indoles , Male , Rabbits , Reserpine/administration & dosage , Serotonin , Spectrum Analysis

16.

[Ultrastructural changes in the rabbit heart following short-term high dosed 60Co whole body irradiation]. / Ultrastrukturelle Veränderungen am Kaninchenherzen nach kurzzeitiger hochdosierter 60Co-Ganzkörperbestrahlung.

Möllmann, H; Decker, S; Alfes, H; Reisch, J.

Strahlentherapie ; 141(4): 451-6, 1971 Apr.

Article in German | MEDLINE | ID: mdl-5557120

Subject(s)

Heart/radiation effects , Radiation Effects , Animals , Cobalt Isotopes , Endoplasmic Reticulum/radiation effects , Microscopy, Electron , Mitochondria, Muscle/radiation effects , Myocardium/pathology , Myofibrils/radiation effects , Rabbits , Radiometry , Time Factors

17.

[Influence of physical stress before and after swim training on hepatic tissue and serum enzyme values in rats]. / Der Einfluss körperlicher Belastung vor und nach Schwimmtraining auf das Leberparenchym und den Serumenzymspiegel bei Rattern.

Möllmann, H; Braun, D; Clasing, D; Alfes, H.

Pflugers Arch ; 328(4): 292-306, 1971.

Article in German | MEDLINE | ID: mdl-5107271

Subject(s)

Enzymes/blood , Liver/pathology , Physical Exertion , Adaptation, Physiological , Alanine Transaminase/blood , Animals , Aspartate Aminotransferases/blood , Cytoplasm , Exercise Test , Female , Fructose-Bisphosphate Aldolase/blood , L-Lactate Dehydrogenase/blood , Liver/metabolism , Liver Glycogen , Microscopy, Electron , Mitochondria, Liver , Rats , Ribosomes , Swimming

18.

[Identification of central stimulants (coping drugs) by mass spectrometry of their NBD-derivatives]. / Die Identifizierung von zentralstimulierenden Arzneistoffen (Dopingmitteln) durch die Massenspektrometrie ihrer NBD-Derivate.

Clasing, D; Alfes, H; Reisch, J; Kommert, H J; Jantos, N; Möllmann, H.

Schweiz Z Sportmed ; 19(3): 41-8, 1971.

Article in German | MEDLINE | ID: mdl-5156562

Subject(s)

Imidazoles/analysis , Phenethylamines/isolation & purification , Spectrum Analysis , Chromatography, Thin Layer , Epinephrine/urine , Humans , Mass Spectrometry , Nitrobenzenes , Substance-Related Disorders

19.

[Comparative studies on the concentration of various trace elements in specific areas of the human brain using neutron activation analysis]. / Vergleichende Untersuchungen über die Konzentration einiger Spurenelemente in menschlichen Vergleichende Untersuchungen über die Konzentration einiger Spurenelemente in menschlichen Hirnarealen durch Neutronenaktivierungsanaylse.

Henke, G; Möllmann, H; Alfes, H.

Z Neurol ; 199(4): 283-94, 1971.

Article in German | MEDLINE | ID: mdl-4104832

Subject(s)

Brain Chemistry , Trace Elements/analysis , Activation Analysis , Barium/analysis , Cesium/analysis , Copper/analysis , Gold/analysis , Humans , Iron/analysis , Lanthanum/analysis , Rubidium/analysis , Selenium/analysis , Silver/analysis , Spectrum Analysis , Zinc/analysis

20.

[Light and electron microscopic findings on liver parenchyma of rabbits after a short-time high-dosage Co60 irradiation]. / Licht- und elektronenmikroskopische Befunde am Leberparenchym von Kaninchen nach kurzzeitiger hochdosierter Co60-Bestrahlung.

Möllmann, H; Reisch, J; Alfes, H; Meyborg, F.

Strahlentherapie ; 140(5): 525-32, 1970 Nov.

Article in German | MEDLINE | ID: mdl-5497599

Subject(s)

Animals , Cobalt Isotopes , Cytoplasm/radiation effects

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